2,176 research outputs found

    The "supply-of-storage" for natural gas in California

    Get PDF
    Do natural gas storage decisions in California respond to futures price spreads? Daily data about flows into and out of storage facilities in California over 2001-2005 and daily price spreads are used to investigate whether the net injection profile is consistent with the "supply-of-storage" curve deduced by Working for wheat. Storage decisions in California do seem to be influenced by intertemporal signals on NYMEX, but the magnitude of the effect is small. Strong seasonal and weekly cycles determine the net injection profile to a considerable extent. Regulatory requirements and operational constraints also limit the size of the response to intertemporal arbitrage opportunities. Results are surprisingly sensitive to the level of aggregation considered.Resource /Energy Economics and Policy,

    Associations of Adiponectin with Adiposity, Insulin Sensitivity, and Diet in Young, Healthy, Mexican Americans and Non-Latino White Adults.

    Get PDF
    Low circulating adiponectin levels may contribute to higher diabetes risk among Mexican Americans (MA) compared to non-Latino whites (NLW). Our objective was to determine if among young healthy adult MAs have lower adiponectin than NLWs, independent of differences in adiposity. In addition, we explored associations between adiponectin and diet. This was an observational, cross-sectional study of healthy MA and NLW adults living in Colorado (U.S.A.). We measured plasma total adiponectin, adiposity (BMI, and visceral adipose tissue), insulin sensitivity (IVGTT), and self-reported dietary intake in 43 MA and NLW adults. Mean adiponectin levels were 40% lower among MA than NLW (5.8 ± 3.3 vs. 10.7 ± 4.2 µg/mL, p = 0.0003), and this difference persisted after controlling for age, sex, BMI, and visceral adiposity. Lower adiponectin in MA was associated with lower insulin sensitivity (R² = 0.42, p < 0.01). Lower adiponectin was also associated with higher dietary glycemic index, lower intake of vegetables, higher intake of trans fat, and higher intake of grains. Our findings confirm that ethnic differences in adiponectin reflect differences in insulin sensitivity, but suggest that these are not due to differences in adiposity. Observed associations between adiponectin and diet support the need for future studies exploring the regulation of adiponectin by diet and other environmental factors

    Modeling of the bubbling process in a planar co-flow configuration

    Get PDF
    This work presents an analytical model developed to describe the bubbling regime resulting from the injection of an air sheet of thickness 2H(o) with a mean velocity u(a) between two water streams of thickness H-w - H-o, moving at a uniform velocity u(w). Based on previous experimental and numerical characterizations of this flow, the gas stream is modeled as a two-dimensional sheet divided into three different parts in the streamwise direction: a neck that moves downstream at the water velocity, a gas ligament attached to the injector upstream of the neck, and a forming bubble downstream of the neck, whose uniform dimensionless half-thicknesses are eta(n)(tau), eta(l)(tau), eta(b)(tau) respectively, and the corresponding pressures are given by Pi(n)(tau), Pi(l)(tau), and Pi(b)(tau) Pi(n)(tau). Lengths are made dimensionless with H-o, and pressures with rho(a)u(a)(2) where rho(a) is the air density.This work has been supported by the Spanish MINECO (Subdi-rección General de Gestión de Ayudas a la Investigación), Junta de Andalucía, and European Funds under projects numbers DPI2014-59292-C3-1-P and DPI2014-59292-C3-3-P, and P11-TEP7495. Financial support from the University of Jaén, project UJA2013/08/05, is also acknowledged

    Mucopolysaccharidosis II, IV-A and VI: First Colombian Neuropsychological Characterization

    Get PDF
    The Mucopolysaccharidosis [MPS] are a group of orphan or rare genetic diseases characterized by lysosomal storage disorders which are recognized by bone malformations and neuropsychological implications that have not been studied so far. For this reason, the first cross-sectional descriptive study of neuropsychological nature was conducted on variants of the disease, Hunter Syndrome [MPS II], Morquio A Syndrome [MPS IV A] and Maroteaux-Lamy syndrome [MPS VI] in 21 children and adolescents aged 3 to 19 years old, at the Colombian Association of Patients with Lysosomal Storage Diseases [ACOPEL, for its Spanish acronym] in Bogotá, Colombia. Results indicate that for the different types of MPS tested is not easy to make a neuropsychological characterization and generalize these results to other populations. However, MPS type II shows moderate to severe cognitive deficit with a compromise in psychomotor development. Morquio A presents average intelligence, and MPS type VI points to deficits partially related to sensory impairment, implying significant differences between them. It is important to continue carrying on this type of studies to achieve a better classification of these diseases according to their cognitive functioning from the neuropsychological perspective

    Polymorphic members of the lag gene family mediate kin discrimination in Dictyostelium

    Get PDF
    Self and kin discrimination are observed in most kingdoms of life and are mediated by highly polymorphic plasma membrane proteins. Sequence polymorphism, which is essential for effective recognition, is maintained by balancing selection. Dictyostelium discoideum are social amoebas that propagate as unicellular organisms but aggregate upon starvation and form fruiting bodies with viable spores and dead stalk cells. Aggregative development exposes Dictyostelium to the perils of chimerism, including cheating, which raises questions about how the victims survive in nature and how social cooperation persists. Dictyostelids can minimize the cost of chimerism by preferential cooperation with kin, but the mechanisms of kin discrimination are largely unknown. Dictyostelium lag genes encode transmembrane proteins with multiple immunoglobulin (Ig) repeats that participate in cell adhesion and signaling. Here, we describe their role in kin discrimination. We show that lagB1 and lagC1 are highly polymorphic in natural populations and that their sequence dissimilarity correlates well with wild-strain segregation. Deleting lagB1 and lagC1 results in strain segregation in chimeras with wild-type cells, whereas elimination of the nearly invariant homolog lagD1 has no such consequences. These findings reveal an early evolutionary origin of kin discrimination and provide insight into the mechanism of social recognition and immunity

    Factores de riesgo asociados a la desnutrición en menores de 5 años del Centro de Salud de Curundú agosto a octubre de 1999

    Get PDF
    Objetivo general: Determinar factores de riesgo asociados a la desnutrición en los niños menores de 5 años del Corregimiento de Curundú en los meses de agosto a octubre de 1999. Objetivos específicos: 1. Describir las características de los casos y controles según las variables del estudio 2. Identificar factores socioeconómicos asociados a la desnutrición. 3. Identificar factores biosicosociales asociados a la desnutrición. 4. Identificar factores ambientales asociados a la desnutrición. 5. Identificar factores relacionados con servicios de salud. 6. Estimar la fuerza de asociación de los presuntos factores de riesgo con la desnutrición

    Novel Glass Material with Low Loss and Permittivity for 5G/6G Integrated Circuits

    Get PDF
    A new borosilicate glass with lower loss and permittivity than any commercial glass has been proposed in this contribution as a substrate or interposer for mm-wave and THz integrated electronics. The glass is composed of a microstructure enclosing high-purity boron rich areas and silicon rich areas. This phase-separated areas are several orders of magnitude smaller than the wavelength at 1 THz
    corecore