60 research outputs found

    Museu de Anatomia: instrumento de democratização do ensino e da inclusão social

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    Anais do 35º Seminário de Extensão Universitária da Região Sul - Área temática: EducaçãoIntrodução: Os museus são instituições culturais que possibilitam a ocorrência de conexões entre o saber científico e a sociedade, constituindo um verdadeiro espaço educacional não formal. Infelizmente, muitas vezes, esses espaços não dispõem de características estruturais e/ou de profissionais capacitados para que a Pessoa com Deficiência possa desfrutar dos bens culturais, com sentimento de pertencimento social. Nesse contexto, o Museu de Anatomia se mostra como instrumento de democratização do conhecimento que busca a cada ano implementar medidas para multiplicar as possibilidades de acesso para todos os tipos de visitantes. Objetivo: Descrever o Projeto de Extensão Museu de Anatomia e suas ações na busca pela democratização do ensino e da inclusão social. Metodologia: O Museu de Anatomia é organizado anualmente na forma de exposição temporária, sendo expostas peças anatômicas e réplicas de obras de arte. Na última edição, foram implementadas medidas para possibilitar acessibilidade a Pessoas com Deficiência auditiva, motora ou intelectual, como tradutores de libras, utilização de legendas virtuais (tablets) e atividades interativas e guiadas por tutores treinados. Resultados: Em 2017, o Museu de Anatomia recebeu 6.366 visitantes, acolhendo 79 instituições de ensino regular e especial ao longo de duas semanas de exposição. Considerações finais: o Museu de Anatomia tem cumprido seu papel como instrumento de democratização do ensino e também de inclusão social quando valoriza as diferenças e promove a acessibilidad

    Cluster analysis applied to recognition of different types of friable siliceous itabirites from Brucutu Mine.

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    A an?lise de agrupamento ? uma t?cnica de estat?stica multivariada que permite separar as unidades amostrais em grupos homog?neos internamente e heterog?neos externamente. Neste estudo essa t?cnica foi aplicada, atrav?s do software R, com o objetivo de estratificar em subgrupos os min?rios classificados como itabiritos silicosos fri?veis da Mina de Brucutu, Quadril?tero Ferr?fero-MG. A matriz de dados era composta por 3.519 amostras e 10 vari?veis granulom?tricas e qu?micas. A an?lise hier?rquica de agrupamento mostrou que as amostras podem ser subdivididas em quatro grupos, e ent?o, as mesmas foram agrupadas pelo m?todo n?o hier?rquico K-means. Atrav?s da an?lise das caracter?sticas de cada grupo formado, os mesmos foram classificados e relacionados com a geologia da jazida. A Tipologia 1 (itabirito silicoso fri?vel rico e fino), ? localizada no topo do dep?sito e estratigraficamente acima das rochas intrusivas m?ficas. A Tipologia 2 (itabirito silicoso fri?vel pobre e grosseiro) ? marcado pela dire??o NW-SE, evento Brasiliano. A Tipologia 3 (itabirito silicoso fri?vel pobre e fino) ? dispersa ao longo do dep?sito, dificultando sua correla??o com alguma fase geol?gica. A Tipologia 4 (itabirito semi-compacto pobre) concentra-se na regi?o SW do dep?sito.Cluster analysis is a multivariate statistical technique that allows to separate the sample units into internally homogeneous and externally heterogeneous groups. In this study the cluster analysis was applied through R software, with the aim of stratifying into subgroups the ores classified as friable siliceous itabirite from the Brucutu Mine, Quadril?tero Ferr?fero, state of Minas Gerais, Brazil. The data matrix consists of 3519 samples and 10 variables related to granulometric and chemical data. The hierarchical clustering analysis showed that the samples could be subdivided into four groups, and then they were grouped by the non-hierarchical K-means method. Through the analysis of the features of each group formed they were classified and related to the geology of the deposit. Typology 1 (friable, Fe-rich and fine siliceous itabirite) is located at the top of the deposit and stratigraphically above the intrusive mafic rocks. Typology 2 (? friable, low grade and coarse siliceous itabirite) is marked by NW-SE direction, Brasiliano event. Typology 3 (friable, low grade and fine siliceous itabirite) is dispersed throughout the deposit, making it difficult to correlate with some geological phase. Typology 4 (low grade semi-compact itabirite) is demarcated by concentration in the SW region of the reservoir

    Upper Airway Expansion in Disabled Children

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    Breathing is essential for life in all of its stages. Cellular, mitochondrial respiration requires an adequate supply of oxygen, provided by the air we breathe, after airway conduction, treatment by the lungs, and transport to tissues. At different stages of life, pediatric dentists and orthodontists can intervene in the upper airway, expanding it, which helps with ventilation. The greater airway space, if used, contributes in different ways to the child’s development and the recovery of respiratory problems and should always be present as a weapon that physicians and the population should know. The value of the techniques becomes even more important when applied to children and young people with disabilities who can significantly improve their development and performance. Rapid Maxillary Expansion and Extraoral Traction Appliances are two important pediatric resources to treat these children. Clinical practice of the authors, is discussed, emphasizing the importance of early intervention and the need for multi and interdisciplinary collaboration in the follow-up of disabled people

    Influence of Temporary Cements on the Bond Strength of Self-Adhesive Cement to the Metal Coronal Substrate

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    This research evaluated the influence of temporary cements (eugenol-containing [EC] or eugenol-free [EF]) on the tensile strength of Ni-Cr copings fixed with self-adhesive resin cement to the metal coronal substrate. Thirty-six temporary crowns were divided into 4 groups (n=9) according to the temporary cements: Provy, Dentsply (eugenol-containing), Temp Cem, Vigodent (eugenol-containing), RelyX Temp NE, 3M ESPE (eugenol-free) and Temp Bond NE, Kerr Corp (eugenol-free). After 24 h of temporary cementation, tensile strength tests were performed in a universal testing machine at a crosshead speed of 0.5 mm/min and 1 kN (100 kgf) load cell. Afterwards, the cast metal cores were cleaned by scraping with curettes and air jet. Thirty-six Ni-Cr copings were cemented to the cast metal cores with self-adhesive resin cement (RelyX U200, 3M ESPE In conclusion, the Provy eugenol-containing temporary cement was associated with the highest bond strength among the resin cements when Ni-Cr copings were cemented to cast metal cores. However, the eugenol cannot be considered a determining factor in increased bond strength, since the other tested cements (1 eugenol-containing and 2 eugenol-free) were similar

    Produção de álcool em gel 70% com diferentes precursores poliméricos / Production of alcohol in gel 70% with different polymeric precursors

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    O presente estudo propõe a utilização de polímeros alternativos para a obtenção de álcool em gel 70% como ferramenta de higiene no combate ao Covid-19. Além da carboximetilcelulose, foram utilizados polímeros comerciais, descritos como derivados da celulose, Carbomex e Maxcarb, os quais apresentam propriedades gelificantes em potencial em diversas áreas. As formulações foram obtidas utilizando diferentes concentrações dos agentes gelificantes com água, glicerina e etanol. Os materiais iniciais, bem como as formulações obtidas, foram caracterizados por diferentes técnicas, incluindo Difração de Raios X, Relaxometria, Análise termogravimétrica.Os resultados das análises de Raios X indicaram uma maior cristalinidade do material obtido com Maxcarb e Carbomex quando comparados à Carboximetilcelulose. A análise termogravimétrica dos materiais indicou que o Maxcarb possui o maior valor de temperatura de degradação. Com as análises de relaxometria foi possível obter os tempos de relaxação dos materiais em solução e nos estado sólido. A Carboximetilcelulose apresentou menor valor de relaxação spin-rede quando comparado ao Maxcarb e Carbomex que apresentaram menores valores

    Sulfated-Polysaccharide Fraction from Red Algae Gracilaria caudata Protects Mice Gut Against Ethanol-Induced Damage

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    The aim of the present study was to investigate the gastroprotective activity of a sulfated-polysaccharide (PLS) fraction extracted from the marine red algae Gracilaria caudata and the mechanism underlying the gastroprotective activity. Male Swiss mice were treated with PLS (3, 10, 30 and 90 mg·kg−1, p.o.), and after 30 min, they were administered 50% ethanol (0.5 mL/25 g−1, p.o.). One hour later, gastric damage was measured using a planimeter. Samples of the stomach tissue were also obtained for histopathological assessment and for assays of glutathione (GSH) and malondialdehyde (MDA). Other groups were pretreated with l-NAME (10 mg·kg−1, i.p.), dl-propargylglycine (PAG, 50 mg·kg−1, p.o.) or glibenclamide (5 mg·kg−1, i.p.). After 1 h, PLS (30 mg·kg−1, p.o.) was administered. After 30 min, ethanol 50% was administered (0.5 mL/25g−1, p.o.), followed by sacrifice after 60 min. PLS prevented-ethanol-induced macroscopic and microscopic gastric injury in a dose-dependent manner. However, treatment with l-NAME or glibenclamide reversed this gastroprotective effect. Administration of propargylglycine did not influence the effect of PLS. Our results suggest that PLS has a protective effect against ethanol-induced gastric damage in mice via activation of the NO/KATP pathway

    SARS-CoV-2 introductions and early dynamics of the epidemic in Portugal

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    Genomic surveillance of SARS-CoV-2 in Portugal was rapidly implemented by the National Institute of Health in the early stages of the COVID-19 epidemic, in collaboration with more than 50 laboratories distributed nationwide. Methods By applying recent phylodynamic models that allow integration of individual-based travel history, we reconstructed and characterized the spatio-temporal dynamics of SARSCoV-2 introductions and early dissemination in Portugal. Results We detected at least 277 independent SARS-CoV-2 introductions, mostly from European countries (namely the United Kingdom, Spain, France, Italy, and Switzerland), which were consistent with the countries with the highest connectivity with Portugal. Although most introductions were estimated to have occurred during early March 2020, it is likely that SARS-CoV-2 was silently circulating in Portugal throughout February, before the first cases were confirmed. Conclusions Here we conclude that the earlier implementation of measures could have minimized the number of introductions and subsequent virus expansion in Portugal. This study lays the foundation for genomic epidemiology of SARS-CoV-2 in Portugal, and highlights the need for systematic and geographically-representative genomic surveillance.We gratefully acknowledge to Sara Hill and Nuno Faria (University of Oxford) and Joshua Quick and Nick Loman (University of Birmingham) for kindly providing us with the initial sets of Artic Network primers for NGS; Rafael Mamede (MRamirez team, IMM, Lisbon) for developing and sharing a bioinformatics script for sequence curation (https://github.com/rfm-targa/BioinfUtils); Philippe Lemey (KU Leuven) for providing guidance on the implementation of the phylodynamic models; Joshua L. Cherry (National Center for Biotechnology Information, National Library of Medicine, National Institutes of Health) for providing guidance with the subsampling strategies; and all authors, originating and submitting laboratories who have contributed genome data on GISAID (https://www.gisaid.org/) on which part of this research is based. The opinions expressed in this article are those of the authors and do not reflect the view of the National Institutes of Health, the Department of Health and Human Services, or the United States government. This study is co-funded by Fundação para a Ciência e Tecnologia and Agência de Investigação Clínica e Inovação Biomédica (234_596874175) on behalf of the Research 4 COVID-19 call. Some infrastructural resources used in this study come from the GenomePT project (POCI-01-0145-FEDER-022184), supported by COMPETE 2020 - Operational Programme for Competitiveness and Internationalisation (POCI), Lisboa Portugal Regional Operational Programme (Lisboa2020), Algarve Portugal Regional Operational Programme (CRESC Algarve2020), under the PORTUGAL 2020 Partnership Agreement, through the European Regional Development Fund (ERDF), and by Fundação para a Ciência e a Tecnologia (FCT).info:eu-repo/semantics/publishedVersio
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