1,489 research outputs found
Engaging youth in post-disaster research: Lessons learned from a creative methods approach
Children and youth often demonstrate resilience and capacity in the face of disasters. Yet, they are typically not given the opportunities to engage in youth-driven research and lack access to official channels through which to contribute their perspectives to policy and practice during the recovery process. To begin to fill this void in research and action, this multi-site research project engaged youth from disaster-affected communities in Canada and the United States. This article presents a flexible youth-centric workshop methodology that uses participatory and arts-based methods to elicit and explore youthâs disaster and recovery experiences. The opportunities and challenges associated with initiating and maintaining partnerships, reciprocity and youth-adult power differentials using arts-based methods, and sustaining engagement in post-disaster settings, are discussed. Ultimately, this work contributes to further understanding of the methods being used to conduct research for, with, and about youth.Keywords: youth, disaster recovery, engagement, resilience, arts-based methods, participatory researc
FRB Email from Katie S Cox to Beverly Smith Re New Filing Citigroup Inc Citi Financial Mortgage
First observed wild birth and acoustic record of a possible infanticide attempt on a common bottlenose dolphin (Tursiops truncatus)
Author Posting. © The Author(s), 2015. This is the author's version of the work. It is posted here by permission of Society for Marine Mammalogy for personal use, not for redistribution. The definitive version was published in Marine Mammal Science 32 (2016): 376â385, doi:10.1111/mms.12248.We observed the birth of a common bottlenose dolphin (Tursiops truncatus) followed immediately by a possible infanticide attempt in the estuary near Savannah, Georgia. Our report is unique in several ways: first, we witnessed the birth of the calf; second, we observed infanticidal behavior almost immediately afterward; and third, we obtained acoustic recordings concurrent with the possible infanticidal behavior. Our observations provide insight into aggressive, possible infanticidal, behavior in bottlenose dolphins.Boat time and support was provided by Department of Education/Title VII Award P382G090003. Additional support was provided by EDGE (Enhancing Diversity in Geosciences Education through Costal Research in Port City) NSF award GEO-0194680.2016-07-1
Exploring Touch as a Positive Workplace Behavior
Whereas most research has focused on the negative aspects of touch in the workplace (i.e. sexual harassment), this study focuses upon the positive use of touch. In an effort to explain individual differences in the use of workplace touch, three sequential studies are used to introduce the concepts of workplace touch self-efficacy and workplace touch initiation anxiety. In Study 1 we develop scales to assess the constructs. Study 2 provides an initial examination of the construct validity of the measures developed in Study 1. Results of Study 3 indicate that supervisor reports of touch self-efficacy and physiological touch anxiety are related to subordinate reports of supervisor touch. Additionally, results show that supervisor use of touch is related to several indicators of supervisor social effectiveness. Finally, sex of the supervisor appears to play a role in workplace touch as female supervisors report less touch anxiety, greater touch self-efficacy and more use of touch than male supervisors
Preventable deaths involving opioids in England and Wales, 2013â2022: a systematic case series of coronersâ reports
Background
Opioid deaths have increased in England and Wales. Coronersâ Prevention of Future Deaths reports (PFDs) provide important insights that may enable safer use and avert harms, yet reports implicating opioids have not been synthesized. We aimed to identify opioid-related PFDs and explore coronersâ concerns to prevent future deaths.
Methods
In this systematic case series, we screened 3897 coronial PFDs dated between 01 July 2013 and 23 February 2022, obtained by web scraping the UKâs Courts and Tribunals Judiciary website. PFDs were included when an opioid was implicated in the death. Included PFDs were descriptively analysed, and content analysis was used to assess concerns reported by coroners.
Results
Opioids were involved in 219 deaths reported in PFDs (5·6% of PFDs), equating to 4418 years of life lost (median 33 years/person). Morphine (29%), methadone (23%) and diamorphine (16%) were the most common implicated opioids. Coroners most frequently raised concerns regarding systems and protocols (52%) or safety issues (15%). These concerns were most often addressed to National Health Service (NHS) organizations (51%), but response rates were low overall (47%).
Conclusions
Opioids could be used more safely if coronersâ concerns in PFDs were addressed by national organizations such as NHS bodies, government agencies and policymakers, as well as individual prescribing clinicians
A cybernetic participatory approach for policy system of systems mapping: Case study of Inclusive Economies
Traditional participatory systems modelling demands synchronous time from many experts and face-to-face interaction. This is not always feasible (e.g., during a pandemic) and can restrict which participants can be included. There are additional limitations in the effectiveness of physical paper-based modelling when handling large complex systems with numerous variables and links between them. The key challenge facing practitioners is then how can we retain the benefits of traditional participatory modelling whilst exploiting the advantages of new technologies? This paper contributes to development of an original systematic methodology inspired by Cybernetic principles. The proposed method, referred to as 5X â standing for Expose, Explore, Exploit, Explain, and Expand â offers a fully virtual co-produced environment for iterative cycle of stakeholder engagement and feedback before, during and after workshops, leading to developing more confidence in systems mapping, and promoting knowledge across policy areas. A primary application of the proposed method in a real policy setting illustrates its capability to generate a shared policy understanding of a complex inclusive economy system, where there is conflicting or dispersed knowledge about system structure, refine this understanding through online feedback channels and dynamic visualisations, and transfer this understanding to wider policy and academic partners
The Naturalistic Flight Deck System: An Integrated System Concept for Improved Single-Pilot Operations
This paper reviews current and emerging operational experiences, technologies, and human-machine interaction theories to develop an integrated flight system concept designed to increase the safety, reliability, and performance of single-pilot operations in an increasingly accommodating but stringent national airspace system. This concept, know as the Naturalistic Flight Deck (NFD), uses a form of human-centered automation known as complementary-automation (or complemation) to structure the relationship between the human operator and the aircraft as independent, collaborative agents having complimentary capabilities. The human provides commonsense knowledge, general intelligence, and creative thinking, while the machine contributes specialized intelligence and control, extreme vigilance, resistance to fatigue, and encyclopedic memory. To support the development of the NFD, an initial Concept of Operations has been created and selected normal and non-normal scenarios are presented in this document
Multivariate modeling to identify patterns in clinical data: the example of chest pain
<p>Abstract</p> <p>Background</p> <p>In chest pain, physicians are confronted with numerous interrelationships between symptoms and with evidence for or against classifying a patient into different diagnostic categories. The aim of our study was to find natural groups of patients on the basis of risk factors, history and clinical examination data which should then be validated with patients' final diagnoses.</p> <p>Methods</p> <p>We conducted a cross-sectional diagnostic study in 74 primary care practices to establish the validity of symptoms and findings for the diagnosis of coronary heart disease. A total of 1199 patients above age 35 presenting with chest pain were included in the study. General practitioners took a standardized history and performed a physical examination. They also recorded their preliminary diagnoses, investigations and management related to the patient's chest pain. We used multiple correspondence analysis (MCA) to examine associations on variable level, and multidimensional scaling (MDS), k-means and fuzzy cluster analyses to search for subgroups on patient level. We further used heatmaps to graphically illustrate the results.</p> <p>Results</p> <p>A multiple correspondence analysis supported our data collection strategy on variable level. Six factors emerged from this analysis: âchest wall syndromeâ, âvital threatâ, âstomach and bowel painâ, âangina pectorisâ, âchest infection syndromeâ, and â self-limiting chest painâ. MDS, k-means and fuzzy cluster analysis on patient level were not able to find distinct groups. The resulting cluster solutions were not interpretable and had insufficient statistical quality criteria.</p> <p>Conclusions</p> <p>Chest pain is a heterogeneous clinical category with no coherent associations between signs and symptoms on patient level.</p
Multivariate proteomic profiling identifies novel accessory proteins of coated vesicles.
Despite recent advances in mass spectrometry, proteomic characterization of transport vesicles remains challenging. Here, we describe a multivariate proteomics approach to analyzing clathrin-coated vesicles (CCVs) from HeLa cells. siRNA knockdown of coat components and different fractionation protocols were used to obtain modified coated vesicle-enriched fractions, which were compared by stable isotope labeling of amino acids in cell culture (SILAC)-based quantitative mass spectrometry. 10 datasets were combined through principal component analysis into a "profiling" cluster analysis. Overall, 136 CCV-associated proteins were predicted, including 36 new proteins. The method identified >93% of established CCV coat proteins and assigned >91% correctly to intracellular or endocytic CCVs. Furthermore, the profiling analysis extends to less well characterized types of coated vesicles, and we identify and characterize the first AP-4 accessory protein, which we have named tepsin. Finally, our data explain how sequestration of TACC3 in cytosolic clathrin cages causes the severe mitotic defects observed in auxilin-depleted cells. The profiling approach can be adapted to address related cell and systems biological questions
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