264 research outputs found

    What You See Is Not What You Know: Deepfake Image Manipulation

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    Research indicates that deceitful videos tend to spread rapidly online and influence people’s opinions and ideas. Because of this, video misinformation via deepfake video manipulation poses a significant online threat. This study aims to discover what factors can influence viewers’ capability of distinguishing deepfake videos from genuine video footage. This work focuses on exploring deepfake videos’ potential use for deception and misinformation by exploring people’s ability to determine whether videos are deepfakes in a survey consisting of deepfake videos and original unedited videos. The participants viewed a set of four videos and were asked to judge whether the videos shown were deepfakes or originals. The survey varied the familiarity that the viewers had with the subjects of the videos. Also, the number of videos shown at one time was manipulated. This survey showed that familiarity of subjects has a statistically significant impact on how well people can determine a deepfake. Notably, however, almost two thirds of study participants (102 out of 154, or 66.23%) were unable to correctly identify a sequence of just four videos as either genuine or deepfake. Overall, the study provides insights into possible methods for countering disinformation and deception resulting from the misuse of deepfakes

    What You See Is Not What You Know: Studying Deception in Deepfake Video Manipulation

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    Research indicates that deceitful videos tend to spread rapidly online and influence people’s opinions and ideas. Because of this, video misinformation via deepfake video manipulation poses a significant online threat. This study aims to discover what factors can influence viewers’ capability to distinguish deepfake videos from genuine video footage. This work focuses on exploring deepfake videos’ potential use for deception and misinformation by exploring people’s ability to determine whether videos are deepfakes in a survey consisting of deepfake videos and original unedited videos. The participants viewed a set of four videos and were asked to judge whether the videos shown were deepfakes or originals. The survey varied the familiarity that the viewers had with the subjects of the videos. Also, the number of videos shown at one time was manipulated. This survey showed that familiarity with subjects has a statistically significant impact on how well people can determine a deepfake. Notably, however, almost two-thirds of study participants (102 out of 154, or 66.23%) were unable to correctly identify a sequence of just four videos as either genuine or deepfake. This study provides insights into possible considerations for countering disinformation and deception resulting from the misuse of deepfakes

    Cumulative and temporal associations between antimicrobial prescribing and community-associated <i>Clostridium difficile</i> infection:population-based case-control study using administrative data

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    Background. Community-associated (CA) Clostridium difficile infection (CDI) is a major public health problem. This study estimates the magnitude of the association between temporal and cumulative prescription of antimicrobials in primary care and CA-CDI. CA-CDI is defined as cases without prior hospitalisation in the previous 12 weeks who were either tested outside of hospital or tested within 2 days of admission to hospital. Methods. Three National patient level datasets –covering CDI cases, community prescriptions and hospitalisations were linked by the NHS Scotland unique patient identifier, the community health index, CHI. All validated cases of CDI from August 2010 to July 2013 were extracted and up to six population-based controls were matched to each case from the CHI register for Scotland. Statistical analysis used conditional logistic regression. Results. 1446 unique cases of CA-CDI were linked with 7964 age, sex and location matched controls. Cumulative exposure to any antimicrobial in the previous 6 months has a monotonic dose-response association with CA-CDI. Individuals with excess of 28 defined daily doses (DDD) to any antimicrobial (19.9% of cases) had an odds ratio (OR)=4.4 (95% CI:3.4-5.6) compared to those unexposed. Individuals exposed to 29+ DDD of high risk antimicrobials (cephalosporins, clindamycin co-amoxiclav, or fluoroquinolones) had an OR=17.9 (95% CI:7.6-42.2). Elevated CA-CDI risk following high risk antimicrobial exposure was greatest in the first month (OR=12.5 (8.9-17.4)) but was still present 4-6 months later (OR=2.6 (1.7-3.9)). Cases exposed to 29+DDD had prescription patterns more consistent with repeated therapeutic courses, using different antimicrobials, than long term prophylactic use. Conclusions. This analysis demonstrated temporal and dose-response associations between CA-CDI risk and antimicrobials with an impact of exposure to high risk antimicrobials remaining 4-6 months later

    Residual effect of community antimicrobial exposure on risk of hospital onset healthcare associated Clostridioides difficile infection:a case-control study using national linked data

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    Background: Associations between antimicrobial exposure in the community and community-associated Clostridioides difficile infection (CA-CDI) are well documented but associations with healthcare-associated CDI (HA-CDI) are less clear. This study estimates the association between antimicrobial prescribing in the community and HA-CDI. Methods: A matched case–control study was conducted by linking three national patient level datasets covering CDI cases, community prescriptions and hospitalizations. All validated cases of HA-CDI (August 2010 to July 2013) were extracted and up to three hospital-based controls were matched to each case on the basis of gender, age, hospital and date of admission. Conditional logistic regression was applied to estimate the association between antimicrobial prescribing in the community and HA-CDI. A sensitivity analysis was conducted to consider the impact of unmeasured hospital antimicrobial prescribing. Results: Nine-hundred and thirty unique cases of HA-CDI with onset in hospital and no hospital discharge in the 12 weeks prior to index admission were linked with 1810 matched controls. Individuals with prior prescription of any antimicrobial in the community had an odds ratio (OR) = 1.41 (95% confidence interval (CI) 1.13–1.75) for HA-CDI compared with those without. Individuals exposed to high-risk antimicrobials (cephalosporins, clindamycin, co-amoxiclav or fluoroquinolones) had an OR = 1.86 (95% CI: 1.33–2.59). After accounting for the likely impact of unmeasured hospital prescribing, the community exposure, particulary to high-risk antimicrobials, was still associated with elevated HA-CDI risk. Conclusions: Community antimicrobial exposure is an independent risk factor for HA-CDI and should be considered as part of the risk assessment of patients developing diarrhoea in hospital

    A classification system for global wave energy resources based on multivariate clustering

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    Better understanding of the global wave climate is required to inform wave energy device design and large-scale deployment. Spatial variability in the global wave climate is analysed here to provide a range of characteristic design wave climates. K-means clustering was used to split the global wave resource into 6 classes in a device agnostic, data-driven method using data from the ECMWF ERA5 reanalysis product. Classification using two sets of input data were considered: a simple set (based on significant wave height and peak wave period) and a comprehensive set including a wide range of relevant wave climate parameters. Both classifications gave resource classes with similar characteristics; 55% of tested locations were assigned to the same class. Two classes were low energy, found in enclosed seas and sheltered regions. Two classes were moderate wave energy classes; one swell dominated and the other in areas with wave action often generated by more local storms. Of the two higher energy classes; one was more often found in the northern hemisphere and the other, most energetic, predominantly on the tips of continents in the southern hemisphere. These classes match existing regional understanding of resource. Consideration of publicly available device power matrices showed good performance was primarily realised for the two highest energy resource classes (25–30% of potential deployment locations); it is suggested that effort should focus on optimising devices for additional resource classes. The authors hypothesise that the low-risk, low variability, swell dominated moderate wave energy class would be most suitable for future exploitation
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