Massive and massless higher spinning particles in odd dimensions

We study actions for massive bosonic particles of higher spins by dimensionally reducing an action for massless particles. For the latter we take a model with a SO(N) extended local supersymmetry on the worldline, that is known to describe massless (conformal) particles of higher spins in flat spacetimes of even dimensions. Dimensional reduction produces an action for massive spinning particles in odd dimensions. The field equations that emerge in a quantization a la Dirac are shown to be equivalent to the Fierz-Pauli ones. The massless limit generates a multiplet of massless states with higher spins, whose first quantized field equations have a geometric form with fields belonging to various types of Young tableaux. These geometric equations can be partially integrated to show their equivalence with the standard Fronsdal-Labastida equations. We covariantize our model to check whether an extension to curved spacetimes can be achieved. Restricting to (A)dS spaces, we find that the worldline gauge algebra becomes nonlinear, but remains first class. This guarantees consistency on such backgrounds. A light cone analysis confirms the presence of the expected propagating degrees of freedom. A covariant analysis is worked out explicitly for the massive case, which is seen to give rise to the Fierz-Pauli equations extended to (A)dS spaces. It is worth noting that in D=3 the massless limit of our model when N goes to infinity has the same field content of the Vasiliev's theory that accommodates each spin exactly once.Comment: 31 page

Particles with non abelian charges

Efficient methods for describing non abelian charges in worldline approaches to QFT are useful to simplify calculations and address structural properties, as for example color/kinematics relations. Here we analyze in detail a method for treating arbitrary non abelian charges. We use Grassmann variables to take into account color degrees of freedom, which however are known to produce reducible representations of the color group. Then we couple them to a U(1) gauge field defined on the worldline, together with a Chern-Simons term, to achieve projection on an irreducible representation. Upon gauge fixing there remains a modulus, an angle parametrizing the U(1) Wilson loop, whose dependence is taken into account exactly in the propagator of the Grassmann variables. We test the method in simple examples, the scalar and spin 1/2 contribution to the gluon self energy, and suggest that it might simplify the analysis of more involved amplitudes.Comment: 14 page

Use of Medicinal Cannabis and Synthetic Cannabinoids in Posttraumatic Stress Disorder (PTSD): a systematic review

Background and Objectives: Post-traumatic stress disorder (PTSD) is a common psychiatric disorder resulting from a traumatic event, is manifested through hyperarousal, anxiety, depressive symptoms, and sleep disturbances. Despite several therapeutic approaches being available, both pharmacological and psychological, recently a growing interest has developed in using cannabis and synthetic cannabinoids stems from their consideration as more efficient and better tolerated alternatives for the treatment of this condition. The present paper aims to evaluate the clinical and therapeutic potentials of medical cannabis and synthetic cannabinoids in treating PTSD patients. Methods: A systematic electronic search was performed, including all papers published up to May 2019, using the following keywords (((cannabis[Title/Abstract]) OR (synthetic cannabinoids [Title/Abstract])) AND ((PTSD[Title/Abstract]) OR (Posttraumatic stress disorder[Title/Abstract]))) for the topics ‘Cannabis’, ‘Synthetic Cannabinoids’, ‘PTSD’, and MESH terms, on the PubMed, Cochrane Library, and Web of Science online databases. For data gathering purposes, PRISMA guidelines were followed. Results were organized into two groups, considering cannabis and synthetic cannabinoids as different therapeutic approaches for PTSD. Results: Present data show that cannabis and synthetic cannabinoids, both acting on the endocannabinoids system, may have a potential therapeutic use for improving PTSD symptoms, e.g., reducing anxiety, modulating memory-related processes, and improving sleep. Conclusions: Even though the current literature suggests that cannabis and synthetic cannabinoids may have a role in the treatment of PTSD, there is currently limited evidence regarding their safety and efficacy. Therefore, additional research is needed in order to better understand the effectiveness and therapeutic usage of these drug classes and monitor their safety.Peer reviewe

Spinning particles and higher spin field equations

Relativistic particles with higher spin can be described in first quantization using actions with local supersymmetry on the worldline. First, we present a brief review of these actions and their use in first quantization. In a Dirac quantization scheme the field equations emerge as Dirac constraints on the Hilbert space, and we outline how they lead to the description of higher spin fields in terms of the more standard Fronsdal-Labastida equations. Then, we describe how these actions can be extended so that the propagating particle is allowed to take different values of the spin, i.e. carry a reducible representation of the Poincar ́e group. This way one may identify a four dimensional model that carries the same degrees of freedom of the minimal Vasiliev’s interacting higher spin field theory. Extensions to massive particles and to propagation on (A)dS spaces are also briefly commented upon

A worldline approach to colored particles

Relativistic particle actions are a useful tool to describe quantum field theory effective actions using a string-inspired first-quantized approach. Here we describe how to employ suitable particle actions in the computation of the scalar contribution to the one-loop gluon effective action. We use the well-known method of introducing auxiliary variables that create the color degrees of freedom. In a path integral they implement automatically the path ordering needed to ensure gauge invariance. It is known that the color degrees of freedom introduced this way form a reducible representation of the gauge group. We describe a method of projecting onto the fundamental representation (or any other chosen irrep, if desired) of the gauge group. Previously, we have discussed the case of anticommuting auxiliary variables. Choosing them to be in the fundamental representation allows to obtain, without any extra effort, also the situation in which the color is given by any antisymmetric tensor product of the fundamental. Here, we describe the novel case of bosonic auxiliary variables. They can be used equivalently for creating the color charges in the fundamental representation. In addition one gets, as a byproduct, the cases where the particle can have the color sitting in any symmetric tensor product of the fundamental. This is obtained by tuning to a different value a Chern Simons coupling, present in the model, which controls how the projection is achieved

Cardiotoxicity related to long-term trastuzumab therapy in metastatic breast cancer: the potential role of treatment duration and cardiac risk factors.

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Recycling of Lithium-Ion Batteries: Overview of Existing Processes, Analysis and Performance

Lithium-ion batteries (LIBs) have become a widespread technology for electrochemical energy storage in the current era of digitalization and transport electrification, being used as electric stationary storage as well as for powering electric vehicles, e-bikes and portable electronic devices such as smartphones and laptops. However, LIBs contain valuable materials, such as cobalt, nickel, lithium and graphite, whose supply has become critical to meet the increasing demand of batteries. Therefore, proper recycling processes are required in order to recover these materials from spent batteries and re-use them to produce new batteries in a sustainable cycle. This contribution provides an extensive survey of the main recycling routes available today, focusing specifically on pyrometallurgical and hydrometallurgical processes based in Europe, North America and Asia. Attention is also devoted to the recycling behaviour of individuals and companies and to the possible ways to increase their recycling rate. The comparison of different processes allows for the ranking of best practices as well as the drawbacks of different process units, with identification of which materials can be recovered, their recovery rate, and an assessment of the overall recycling efficiency of the process for different battery sizes (small and large, for portable electronics and electric vehicles, respectively). The analysis reveals that pyrometallurgical processes can flexibly treat different LIB chemistries but, since the electrolyte and graphite are burnt in the process, the global recycling efficiency cannot compete with hydrometallurgical processes, especially for small format batteries. Nevertheless, hydrometallurgical processes typically require preliminary mechanical separation treatments to separate the black mass, which contains valuable electrodic materials, as well as complex precipitation steps, which eventually reduce the material recovery rate and the applicability to diverse LIB chemistries. Finally, the study reports an analysis of the electrochemical performance of a battery made with recycled materials, showing that even if recycled cathodic materials had a lower gravimetric capacity and solid-state diffusivity, the performance of a recycled battery could be compensated by simple minor changes to the cell design which would ultimately decrease the specific energy density by a few percent compared to a LIB made with virgin materials