The role of proximal and distal influences on relationship termination adjustment in college students

The purpose of the present study was to investigate gender and age differences in dealing with a romantic relationship breakup, as well as to investigate the role that distal (childhood events and childhood attachment) and proximal (personality, perceived stress, coping, and adult attachment) influence one\u27s adjustment to an ended romantic relationship. Participants for this study included 252 (160 women and 92 men) college students, with age ranges from 18 to 39. Two (Age) X Two (Gender) analyses of covariance were computed to assess mean differences for all variables. Women reported higher Neuroticism, Extraversion, and Agreeableness scores than men, whereas men displayed higher levels of Openness to Experience than did women. Regarding coping, women utilized (on average) more instrumental support than did men. Men experienced significantly more life events during the period from sixth to eighth grade than did women. In addition, regarding total life events, older female students had the fewest childhood life events whereas older male students had the highest numbers of childhood life events. Multiple regression analyses were then used to determine the influence of eight covariates on relationship termination adjustment (RTA). One covariate, commitment to the former relationship, was a significant predictor of the three measures of RTA (grief, disentanglement, and self-worth). Finally, structural equation modeling was used. Five structural models (each utilizing one of the five traits (Neuroticism, Extraversion, Openness, Agreeableness, and Conscientiousness) measured by the NEO-FFI were compared regarding the respective model\u27s ability to most comprehensively explain and predict RTA. Of these five models, the Neuroticism structural model of RTA had a good fit (CFI = .98) to the data and provided the most significant pathways relevant to the developmental outcome (RTA) of all the models computed. Based on this model, multiple group comparisons regarding both gender and age were performed to determine if these variables act as moderators in RTA. In both comparisons, neither gender nor age acted as a moderator regarding how one deals with an ended relationship. Future research needs to examine the developmental trajectories involved in adjusting to an ended romantic relationship

Episioplasty In The Broodmare

Episioplasty or plastic repair of the vulvo-perineal region is indicated in the case of the barren broodmare whose infertility is due to faulty conformation in this region or to vulvar defects. By means of this relatively simple operation, otherwise useless mares may be returned to the ranks of valuable producers

Study of the Effects of the Arkansas River Chloride Control Projects and the Need for a Water Quality Monitoring System

Civil Engineerin

Elucidating cannabinoids’ effects on Ewing’s sarcoma tumor vasculature

To elucidate the mechanism by which AJA affects Ewing’s Sarcoma cellular pathways, we conducted an angiogenic array to observe AJA’s effects on fifty-five different angiogenic proteins. The angiogenic array showed potential upregulation of TIMP-1, an angiogenic inhibitor, but similar results have yet to be replicated in subsequent ELISA’s. Solid tumors commonly have high vascular densities and increased interstitial fluid pressures (IFP), which reduce the efficacy of treatments by inhibiting the absorption of therapeutic drugs. To determine the effects of AJA and CBD on IFP, and thus on vasculature in vivo, we measured IFP levels in mouse xenograft ES tumors. AJA and CBD both produced significant decreases in IFP within thirty minutes of injection, affirming their potential as legitimate cancer treatments

ESTRO IORT Task Force/ACROP recommendations for intraoperative radiation therapy in borderline-resected pancreatic cancer

Radiation therapy (RT) is a valuable component of multimodal treatment for localized pancreatic cancer. Intraoperative radiation therapy (IORT) is a very precise RT modality to intensify the irradiation effect for cancer involving upper abdominal structures and organs, generally delivered with electrons (IOERT). Unresectable, borderline and resectable disease categories benefit from dose-escalated chemoradiation strategies in the context of active systemic therapy and potential radical surgery. Prolonged preoperative treatment may act as a filter for selecting patients with occult resistant metastatic disease. Encouraging survival rates have been documented in patients treated with preoperative chemoradiation followed by radical surgery and IOERT (>20 months median survival, >35% survival at 3 years). Intensive preoperative treatment, including induction chemotherapy followed by chemoradiation and an IOERT boost, appears to prolong long-term survival within the subset of patients who remain relapse-free for>2 years (>30 months median survival; >40% survival at 3 years). Improvement of local control through higher RT doses has an impact on the survival of patients with a lower tendency towards disease spread. IOERT is a well-accepted approach in the clinical scenario (maturity and reproducibility of results), and extremely accurate in terms of dose-deposition characteristics and normal tissue sparing. The technique can be adapted to systemic therapy and surgical progress. International guidelines (National Comprehensive Cancer Network or NCCN guidelines) currently recommend use of IOERT in cases of close surgical margins and residual disease. We hereby report the ESTRO/ACROP recommendations for performing IOERT in borderline-resectable pancreatic cancer