Measurement of optical response of a detuned resonant sideband extraction gravitational wave detector

We report on the optical response of a suspended-mass detuned resonant sideband extraction (RSE) interferometer with power recycling. The purpose of the detuned RSE configuration is to manipulate and optimize the optical response of the interferometer to differential displacements (induced by gravitational waves) as a function of frequency, independently of other parameters of the interferometer. The design of our interferometer results in an optical gain with two peaks: an RSE optical resonance at around 4 kHz and a radiation pressure induced optical spring at around 41 Hz. We have developed a reliable procedure for acquiring lock and establishing the desired optical configuration. In this configuration, we have measured the optical response to differential displacement and found good agreement with predictions at both resonances and all other relevant frequencies. These results build confidence in both the theory and practical implementation of the more complex optical configuration being planned for Advanced LIGO

Measurement of Optical Response of a Detuned Resonant Sideband Extraction Interferometer

We report on the optical response of a suspended-mass detuned resonant sideband extraction (RSE) interferometer with power recycling. The purpose of the detuned RSE configuration is to manipulate and optimize the optical response of the interferometer to differential displacements (induced by gravitational waves) as a function of frequency, independently of other parameters of the interferometer. The design of our interferometer results in an optical gain with two peaks: an RSE optical resonance at around 4 kHz and a radiation pressure induced optical spring at around 41 Hz. We have developed a reliable procedure for acquiring lock and establishing the desired optical configuration. In this configuration, we have measured the optical response to differential displacement and found good agreement with predictions at both resonances and all other relevant frequencies. These results build confidence in both the theory and practical implementation of the more complex optical configuration being planned for Advanced LIGO.Comment: 6 pages, 4 figures, for submission to Phys Rev Letter

Bioinspired silica as drug delivery systems and their biocompatibility

Silica nanoparticles have been shown to have great potential as drug delivery systems (DDS), however, their fabrication often involves harsh chemicals and energy intensive laborious methods. This work details the employment of a bioinspired "green" method for the controlled synthesis of silica, use of the products to entrap and release drug molecules and their cytotoxicity in order to develop novel DDS. Bioinspired silica synthesis occurs at pH 7, room temperature and in less than 5 minutes, resulting in a rapid, cheaper and greener route. Drugs were loaded into silica during the silica formation, thus allowing a one step and one pot method for simultaneous silica synthesis and drug loading. We established that the drug release profile can be modulated by synthetic parameters, which can allow design of tailored DDS. A systematic investigation using a two level factorial design was adopted in order to identify the key synthetic parameters and quantify their effects on silica formation, drug loading and drug release. The observation that these new DDS are considerably less cytotoxic than their current counterparts, and exhibit additional benefits such as green synthesis and ease of functionalization, strengthens the argument for their future use in DDS and other biomedical applications. © 2014 the Partner Organisations

Le tea party français:Mirror movements and grassroots protest

The presence of grassroots social protest movements which agitate against economic concerns is a prevalent issue in modern politics. While populism on both the political left and right is evident in national electoral contests there also exists activism at the grassroots level. The campaigns of the Bonnets Rouges in Brittany witnessed many ideas and understandings similar to the Tea Party protests in the United States. Both founded movements based upon historical nostalgia, both mobilised against economic discontent and both perceived themselves to be rooted outside the conventional political parameters of left and right. In this article we examine whether there is evidence of movements learning from one another and how peer-peer observation of grassroots activism may influence activist organization

Simultaneous generation of many RNA-seq libraries in a single reaction

Although RNA-seq is a powerful tool, the considerable time and cost associated with library construction has limited its utilization for various applications. RNAtag-Seq, an approach to generate multiple RNA-seq libraries in a single reaction, lowers time and cost per sample, and it produces data on prokaryotic and eukaryotic samples that are comparable to those generated by traditional strand-specific RNA-seq approaches

Nurturing the talent pipeline for an emerging global workforce

Passion. IMSA’s ability to produce thinkers and problem solvers doesn’t just breed pragmatists who know what it takes to be successful – it also gives students the chance to discover their passion. The more they try and the more they experience, the more they discover what they love. The chance to pursue passion means graduates have a greater sense of vision – and a greater chance of realizing their true potential. IMSA teaches students to be global citizens in a diverse world. IMSA embraces diverse perspectives enriching understanding and the knowledge, attitudes, and skills required to function as multicultural citizens in a global world. The false perception that IMSA is just a school for smart kids might blind people from seeing what truly makes IMSA special. There are plenty of places to be smart – IMSA shares in the responsibility to enable students to be successful in the emerging future of a global workforce

The impact of quality and accessibility of primary care on emergency admissions for a range of chronic ambulatory care sensitive conditions (ACSCs) in Scotland:longitudinal analysis

Funding This research was funded by the Chief Scientist Office (grant CZH/4/916). Health Economics Research Unit is funded by the Chief Scientist Office of the Scottish Government Health Directorate. AL is funded by the Medical Research Council (MC_UU_12017/13) and the Chief Scientist Office of the Scottish Government Health Directorate (SPHSU13)Peer reviewedPublisher PD

1936: Abilene Christian College Bible Lectures - Full Text

Delivered in the auditorium of Abilene Christian College, Abilene, Texas, February 193

Estimating Natal Origins of Migratory Juvenile Northern Goshawks Using Stable Hydrogen Isotopes

From 2004 to 2007, we collected hatch-year feathers from 44 juvenile Northern Goshawks (Accipiter gentilis) captured at our Rocky Mountain Front banding station near Lincoln, Montana. Due to the relative scarcity and secretive nature of goshawks, little is understood about their migration patterns or the geographic origins of birds encountered at research sites. Most studies suggest goshawks are partial migrants, often moving <100km, but select band returns and radio and satellite telemetry have shown some individuals occasionally travel thousands of kilometers. We performed a stable hydrogen isotope analysis on the feathers we collected from young goshawks to determine their predicted natal origin. We found that 68% of goshawks had predicted natal origins relatively close to our capture site, 25% from areas in northwestern Canada and eastern Alaska, and 7% somewhere significantly south or east of our capture site. We did not find any significant patterns with sex and passage date or latitudinal origin, nor did we find a meaningful relationship between latitudinal origin and passage date. Our findings support the current understandings of goshawk migration, with a majority of individuals traveling short distances from their natal grounds and a few outliers traveling great distances, not always in a southerly direction