Maternal Characteristics and Child Problem Behaviors: A Comparison of Foster and Biological Mothers

The purpose of this exploratory study was to compare the parenting behavior, stress and support of foster mothers and biological mothers of young children. A sample of 60 mothers of young children (30 foster mothers, 30 biological mothers) completed measures of parenting behavior, parenting stress, child problem behaviors, and perceived social support. Findings indicated that biological mothers were single and younger than foster mothers. In addition, biological mothers utilized more verbal and corporal discipline than foster mothers, experienced greater parental distress and received less social support for their parenting. Implications of these findings are discussed

Unusually High Body Mass in Virginia Meadow Voles

We used monthly capture-mark-recapture information to determine growth rates and life spans for 2 populations of meadow voles studied for 28 and 29 months in eastern Virginia in order to learn whether the exceptionally large body masses of some voles were due to rapid growth, long lives, or both. On 1 study grid, 64 males (19%) and 43 nonpregnant females (11%) were ≥70 g, with the largest male being 89 g. Mostly positive growth rates (averaging 1.1-3.9 g/month) were recorded, even in autumn and winter months, times when meadow voles are losing mass in northern populations, where most studies of body growth have been conducted. Periods of low mean body mass were associated with low population density more than high body mass was associated with high population density. Patterns of body mass dynamics were related more to season than to density in our populations. We concluded that the large body masses we observed in some voles were due more to long field lives than to unusually high rates of body growth

Water-soluble material on aerosols collected within volcanic eruption clouds

In February and March of 1978, filter samplers mounted on an aircraft were used to collect the aerosol fraction of the eruption clouds from three active Guatemalan volcanoes (Fuego, Pacaya, and Santiaguito). The samples were collected on Teflon (Fluoropore) filters with a nominal pore diameter of 0.5μm. The mass of air sampled by the filters ranged from 0.15 to 6.6 kg. The particulate material collected consisted of fragments of angular silicate ash and droplets of what is interpreted as dilute H2SO4 and HCl. After collection of the samples, each filter was rinsed with 60 ml of distilled-deionized water. Splits of each extract were centrifuged to remove particles greater than or equal to 0.1 μm in diameter, acidified, and analyzed for B, Ba, Be, Ca, Cd, Co, Cu, Fe, Li, Mg, Mn, Mo, Na, Pb, Si, Sr, V, and Zn by inductively coupled plasma—optical emission spectroscopy. Separate splits were analyzed for F and Cl by specific-ion-electrode methods and for U by a fission track technique. The elements dissolved in the aqueous extracts represent components of water-soluble material either formed directly in the eruption cloud or derived from interaction of ash particles and aerosol components of the plume. Calculations of enrichment factors, based upon concentration ratios, showed the elements most enriched in the extracts relative to bulk ash composition were Cd, Cu, V, F, Cl, Zn, and Pb. These elements represent a subset (with the addition of Cl and F) of elements previously reported enriched in atmospheric aerosols in remote regions as well as in volcanic areas. This suggests that some of the enriched elements were widely dispersed as volatile halides emitted from a volcanic source

Collaborative International Research in Clinical and Longitudinal Experience Study in NMOSD

Objective To develop a resource of systematically collected, longitudinal clinical data and biospecimens for assisting in the investigation into neuromyelitis optica spectrum disorder (NMOSD) epidemiology, pathogenesis, and treatment. Methods To illustrate its research-enabling purpose, epidemiologic patterns and disease phenotypes were assessed among enrolled subjects, including age at disease onset, annualized relapse rate (ARR), and time between the first and second attacks. Results As of December 2017, the Collaborative International Research in Clinical and Longitudinal Experience Study (CIRCLES) had enrolled more than 1,000 participants, of whom 77.5% of the NMOSD cases and 71.7% of the controls continue in active follow-up. Consanguineous relatives of patients with NMOSD represented 43.6% of the control cohort. Of the 599 active cases with complete data, 84% were female, and 76% were anti-AQP4 seropositive. The majority were white/Caucasian (52.6%), whereas blacks/African Americans accounted for 23.5%, Hispanics/ Latinos 12.4%, and Asians accounted for 9.0%. The median age at disease onset was 38.4 years, with a median ARR of 0.5. Seropositive cases were older at disease onset, more likely to be black/African American or Hispanic/Latino, and more likely to be female. Conclusions Collectively, the CIRCLES experience to date demonstrates this study to be a useful and readily accessible resource to facilitate accelerating solutions for patients with NMOSD

Understanding Policies, Projects, Initiatives & Strategies as a Valuable Source of Research Data in Educational Context

Policies, Projects, Initiatives, and Strategies (PPIS) are often developed and implemented in education to improve educational outcomes in the country and the globe. While these efforts are typically evaluated using various metrics, there is growing interest in using PPIS as a research data source to gain insights into their development and impact. This paper provides a comprehensive review of the existing literature on the use of PPIS. We begin by defining PPIS and describing the four components (Policies, Projects, Initiatives, and Strategies) while highlighting the significance of using PPIS data. We then review selected studies that have successfully used PPIS as a research data source, including examples from developed and developing countries. We also provide a thorough review of previous research studies that used PPIS data; practical guidance on how researchers can access and analyze PPIS data; the legal and ethical considerations and emerging trends that must be considered. Finally, utilizing PPIS data can inform decision-making and policy development in the field of education, which can promote positive change. Therefore, researchers need to consider utilizing PPIS data to gain insights into policy implementation and effectiveness, ultimately improving educational systems and outcomes. Keywords: Policies, Projects, Initiatives & Strategies (PPIS), Source of Research Data, Education Research DOI: 10.7176/JEP/15-4-06 Publication date:March 31st 202

Mineral Element Analyses of Switchgrass Biomass: Comparison of the Accuracy and Precision of Laboratories

Mineral concentration of plant biomass can affect its use in thermal conversion to energy. The objective of this study was to compare the precision and accuracy of university and private laboratories that conduct mineral analyses of plant biomass on a fee basis. Accuracy and precision of the laboratories was tested by having all laboratories conduct mineral analyses on subsamples of the same set of standard switchgrass (Panicum virgatum L.) samples and a certified standard. Laboratories differed significantly in both accuracy and precision even though several used the same analysis method indicating that the differences among laboratories were due to within laboratory procedures and quality control. Laboratories should be using sample standards to monitor both precision and accuracy of their mineral analyses. It would be advisable for researchers submitting samples to service laboratories to replicate the unknown samples to determine precision and to include replicated standards among the submitted samples to determine accuracy

Panel Discussion On The Management Of Allergies In Geriatric Patients†

Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/111236/1/jgs00790.pd

Superoxide dismutase downregulation in osteoarthritis progression and end-stage disease

Oxidative stress is proposed as an important factor in osteoarthritis (OA). To investigate the expression of the three superoxide dismutase (SOD) antioxidant enzymes in OA. SOD expression was determined by real-time PCR and immunohistochemistry using human femoral head cartilage. SOD2 expression in Dunkin–Hartley guinea pig knee articular cartilage was determined by immunohistochemistry. The DNA methylation status of the SOD2 promoter was determined using bisulphite sequencing. RNA interference was used to determine the consequence of SOD2 depletion on the levels of reactive oxygen species (ROS) using MitoSOX and collagenases, matrix metalloproteinase 1 (MMP-1) and MMP-13, gene expression. All three SOD were abundantly expressed in human cartilage but were markedly downregulated in end-stage OA cartilage, especially SOD2. In the Dunkin–Hartley guinea pig spontaneous OA model, SOD2 expression was decreased in the medial tibial condyle cartilage before, and after, the development of OA-like lesions. The SOD2 promoter had significant DNA methylation alterations in OA cartilage. Depletion of SOD2 in chondrocytes increased ROS but decreased collagenase expression. This is the first comprehensive expression profile of all SOD genes in cartilage and, importantly, using an animal model, it has been shown that a reduction in SOD2 is associated with the earliest stages of OA. A decrease in SOD2 was found to be associated with an increase in ROS but a reduction of collagenase gene expression, demonstrating the complexities of ROS function

Structure of an Early Intermediate in the M-State Phase of the Bacteriorhodopsin Photocycle

AbstractThe structure of an early M-intermediate of the wild-type bacteriorhodopsin photocycle formed by actinic illumination at 230K has been determined by x-ray crystallography to a resolution of 2.0Å. Three-dimensional crystals were trapped by illuminating with actinic light at 230K, followed by quenching in liquid nitrogen. Amide I, amide II, and other infrared absorption bands, recorded from single bacteriorhodopsin crystals, confirm that the M-substate formed represents a structure that occurs early after deprotonation of the Schiff base. Rotation about the retinal C13—C14 double bond appears to be complete, but a relatively large torsion angle of 26° is still seen for the C14—C15 bond. The intramolecular stress associated with the isomerization of retinal and the subsequent deprotonation of the Schiff base generates numerous small but experimentally measurable structural changes within the protein. Many of the residues that are displaced during the formation of the late M (MN) substate formed by three-dimensional crystals of the D96N mutant (Luecke et al., 1999b) are positioned, in early M, between their resting-state locations and the ones which they will adopt at the end of the M phase. The relatively small magnitude of atomic displacements observed in this intermediate, and the well-defined positions adopted by nearly all of the atoms in the structure, may make the formation of this structure favorable to model (simulate) by molecular dynamics

The Metropolis and Evangelical Life: Coherence and Fragmentation in the ‘Lost City of London’

This article examines the interplay of different processes of cultural and subjective fragmentation experienced by conservative evangelical Anglicans, based on an ethnographic study of a congregation in central London. The author focuses on the evangelistic speaking practices of members of this church to explore how individuals negotiate contradictory norms of interaction as they move through different city spaces, and considers their response to tensions created by the demands of their workplace and their religious lives. Drawing on Georg Simmel’s ‘The Metropolis and Mental Life’, the author argues that their faith provides a sense of coherence and unity that responds to experiences of cultural fragmentation characteristic of everyday life in the city, while simultaneously leading to a specific consciousness of moral fragmentation that is inherent to conservative evangelicalism