957 research outputs found

    Preserving Music Recitals

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    Session "Local Digitization Case Studies: Making Local Collections Global", presented at the Electronic Resources and Libraries Conference, Austin, Texas, April 5, 2017.This session seeks to present a series of impactful case studies showcasing locally designed and implemented digitization workflows that serve the source material and its designated community while complimenting the institutional context

    Argentina: Pandemia, aislamiento y parálisis de la producción audiovisual

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    La crisis preexistente de la fcción nacional que Obitel Argentina reporta al menos desde el año 2010 se agudizó en el contexto de pandemia cuando los canales de aire estrenaron apenas cuatro títulos argentinos que representaron 61 horas y una coproducción, la cifra más bajadesde que llevamos registro. Los canales líderes, en especial Telefe,obtuvieron buenos resultados de audiencia programando numerosas telenovelas de origen brasileño y turco. Si es cierto que las corporacionesmediáticas tienen todo su pasado por delante, la pandemia les permitióreponer con éxito moderado algunas fcciones que fueron sucesos ensus emisiones originales. Los datos que aquí exponemos muestran lacompleta parálisis de la producción nacional, un incremento abrupto einusual de reposiciones de distinto origen, el retorno de las narco telenovelas a la TV abierta y el rol destacado de la Televisión Pública en laemisión de un número signifcativo de títulos nacionales, algunos estrenos, y especialmente reposiciones (Nicolosi, 2021) que permitierona los actores el cobro de las regalías por derechos de intérprete, un datorelevante en un contexto crítico y de virtual parálisis para la industriade la fcción en su conjunto.Fil: Kirchheimer, Monica Susana. Universidad Nacional de las Artes; Argentina. Universidad de Buenos Aires. Facultad de Ciencias Sociales. Instituto de Investigaciones "Gino Germani"; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaFil: Rivero, Ezequiel Alexander. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universidad Nacional de Quilmes. Departamento de Ciencias Sociales; Argentin

    Supplementation of arachidonic acid rich oil in European sea bass juveniles (Dicentrarchus labrax) diets: Effects on growth performance, tissue fatty acid profile and lipid metabolism

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    The aim of this study was to evaluate the effects of increasing dietary arachidonic acid (ARA) levels (from 1 up to 6 % of total fatty acids) on European sea bass (Dicentrarchus labrax) juveniles growth performance, tissue fatty acid profile, liver morphology as well as long chain polyunsaturated fatty acids (LC-PUFA) biosynthesis, triglyceride and cholesterol synthesis and lipid transport. A diet with total fish oil (FO) replacement and defatted fish meal (FM) containing a 0.1 g ARA g-1 diet was added to the experimental design as a negative control diet. Dietary ARA inclusion levels below 0.2 g ARA g-1 diet significantly worsened growth even only 30 days after the start of the feeding trial, whereas dietary ARA had no effect on fish survival. Liver, muscle and whole body fatty acid profile mainly reflected dietary contents and ARA content increased accordingly with ARA dietary levels. Tissue eicosapentaenoic acid (EPA), docosapentaenoic acid (DPA) and docosahexaenoic acid (DHA) levels were positively correlated among them. Hepatic lipid vacuolization increased with reduced dietary ARA levels. Expressions of fatty acyl desaturase 2 and 3-hydroxy-3-methylglutaryl-coenzyme genes were up-regulated in fish fed the negative control diet compared to the rest of the dietary treatments denoting the influence of ARA on lipid metabolism. Results obtained highlight the need to include adequate n-6 levels and not only n-3 LC-PUFA levels in European sea bass diets. Keywords: Dicentrarchus labrax, arachidonic acid, growth performance, tissue fatty acid profile, lipid metabolis

    Redes sociais e qualidade de vida relacionada à saúde em estudantes universitários

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    Introduction: Social networks provide young people with the opportunity to be in touch with society and their environment, for which they spend a great amount of time to seek acceptance from their peers. Materials and Methods: A cross-sectional descriptive correlational study was conducted on a sample of 400 students. Two questionnaires were used to collect information. For variable comparison, Spearman’s rank correlation coefficient and Chi-squared test were used. Results: 354 (88.5%) of university students have a mobile device with internet connection; 184 (46%) use 3 to 4 social networks and 196 (49%) use them for about 1 to 4 hours a day. 157 (39.2%) claimed that their studies were not affected by using social networks. As for general health, Colombians scored 58.5 and Mexicans 38.3 on a scale of 0 to 100. Discussion: Young people spend most of their time using social networks, being particularly interested in social relationships with their peers. Some studies suggest an association between internet misuse and physical and psychosocial health problems. Conclusions: Social network use behavior and quality of life perception are similar in Colombia and Mexico. In addition, social networks are moderately used as an academic and socialization tool. There is a need for opportunities to share with peers in which social networks are not used as a mediator. Como citar este artículo: Hanna MI, Ocampo MM, Janna NM, Mena MC, Torreglosa LD. Redes sociales y calidad de vida relacionada con la salud en estudiantes universitarios. Rev Cuid. 2020; 11(1): e953. http://dx.doi.org/10.15649/cuidarte.953Introducción: Las redes sociales permite a los jóvenes estar en contacto con la sociedad y su entorno, gran cantidad del tiempo lo emplean en su uso, buscando aceptación por sus pares. Materiales y Métodos: Investigación descriptiva, transversal, correlacional. La muestra estuvo conformada por 400 estudiantes. La información se recolectó, mediante la utilización de dos cuestionarios. Para la comparación entre las variables, se empleó el coeficiente de correlación de Spearman y Chi cuadrado. Resultados: 354 (88,5%) de los universitarios tienen un dispositivo móvil con conexión a internet; 184 (46%) consultan entre 3 a 4 redes sociales, aproximadamente de 1 a 4 horas diarias 196 (49%).  157 (39.2%) manifestaron no ver afectada la academia por el uso de redes sociales. La salud general, en una escala de 0 a 100, obtuvo una puntuación de 58,5 por los colombianos y de 38,3 en los mexicanos. Discusión: Los jóvenes dedican mayor cantidad de su tiempo en el uso de redes sociales, siendo su interés especial, las relaciones entre pares. Algunos estudios coinciden en que existe una asociación entre el mal uso del internet y problemas de salud físicos y psicosociales. Conclusiones: El comportamiento de uso de las redes sociales y la percepción de calidad de vida es similar en Colombia y en México; además consideran que son usadas moderadamente como herramienta académica y de socialización. Es necesario espacios para compartir con iguales, en los cuales no se necesite de las redes sociales como mediador. Como citar este artículo: Hanna MI, Ocampo MM, Janna NM, Mena MC, Torreglosa LD. Redes sociales y calidad de vida relacionada con la salud en estudiantes universitarios. Rev Cuid. 2020; 11(1): e953. http://dx.doi.org/10.15649/cuidarte.953Introdução: As redes sociais permitem que os jovens entrem em contato com a sociedade e seu ambiente, para o qual passam muito tempo a procurar a aceitação por parte dos seus semelhantes. Materiais e Métodos: Um estudo transversal descritivo e correlacional foi realizado em uma amostra de 400 alunos. As informações foram coletadas por meio de dois questionários. Para a comparação de variáveis, foram utilizados o coeficiente de correlação de postos de Spearman e o teste do qui-quadrado. Resultados: 354 (88,5%) dos universitários possuem telefone celular com conexão à Internet; 184 (46%) utilizam de 3 a 4 redes sociais e 196 (49%) as utilizam por cerca de 1 a 4 horas por dia. 157 (39,2%) afirmaram que a academia não foi afetada pelo uso de redes sociais. A saúde geral, em uma escala de 0 a 100, obteve 58,5 para os colombianos e 38,3 para os mexicanos. Discussão: Os jovens passam mais tempo usando redes sociais, com seu interesse especial nas relações com os seus semelhantes. Alguns estudos sugerem uma associação entre uso indevido da internet e problemas de saúde físicos e psicossociais. Conclusões: O comportamento de uso das redes sociais e a percepção de qualidade de vida são semelhantes na Colômbia e no México. Além disso, as redes sociais são usadas ​​moderadamente como uma ferramenta acadêmica e de socialização. Você precisa de espaços para compartilhar com iguais, nos quais não precisa de redes sociais como mediador. Como citar este artículo: Hanna MI, Ocampo MM, Janna NM, Mena MC, Torreglosa LD. Redes sociales y calidad de vida relacionada con la salud en estudiantes universitarios. Rev Cuid. 2020; 11(1): e953. http://dx.doi.org/10.15649/cuidarte.95

    Comportamiento de indicadores de calidad en Instituciones Prestadoras de Servicios de Salud. Montería, 2015

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    Objective: To determine the performance of quality indicators in Health Services Providers (IPS) of second and third level of care, in Monteria. Methodology: Quantitative descriptive study, a retrospective analysis of the performance of the results of a series of quality indicators was carried out. The information was obtained from the Health Quality Indicators Database of the Ministry of Health and Social Protection. The population and sample was 13 IPS of the second and third level of care, which reported information to the Ministry of Health and Social Protection. The study was conducted in 2015; however, data were also found from year 2013, therefore, information was collected from the last three periods (2011-2013). Results: 57% of the reports correspond to IPS of the third level. The rate of readmissions of hospitalized patients was 5.06 X 100; In-hospital mortality after 48 hours was 6.8 x 1000, the average number of infections associated with care was 7.5 per 100 hospitalized patients, the management of adverse events threw an average of 84%, it was also evident the lack of data reported by some IPS. Conclusions: IPS must establish mechanisms that guarantee the analysis of indicators as close to real time as possible, in order to make timely decisions. The measurement of quality indicators will allow for a better monitoring of the control entities.Objetivo. Determinar el comportamiento de los indicadores de calidad en Instituciones Prestadoras de Servicios de Salud (IPS) de segundo y tercer nivel de atención, en la ciudad de Montería. Metodología. Estudio descriptivo cuantitativo, se realizó análisis retrospectivo del comportamiento de los resultados de una serie de indicadores de calidad. La información se obtuvo de la Base de datos de indicadores de calidad en salud del Ministerio de Salud y Protección Social. La población y muestra fue de 13 IPS de segundo y tercer nivel de atención, que reportaron información ante el Ministerio de Salud y de la Protección Social, el estudio se realizó en el año 2015; sin embargo, se encontraron datos hasta el año 2013, por lo tanto, se recolectó información de los tres últimos períodos (2011 -2013). Resultados. El 57% de los reportes corresponden a IPS de tercer nivel. La tasa de reingresos de pacientes hospitalizados, fue de 5,06 X 100; la mortalidad intrahospitalaria después de 48 horas fue de 6,8 x 1000, el promedio de infecciones asociadas a la atención fue de 7,5 por cada 100 pacientes hospitalizados, la gestión de los eventos adversos obtuvo un promedio de 84%, además se evidenció la falta de reporte de datos por parte de algunas IPS. Conclusiones. Las IPS deben establecer mecanismos, que garanticen el análisis de indicadores lo más cercano al tiempo real, para tomar decisiones oportunas. La medición de indicadores de calidad, permitirá un mejor monitoreo a los entes de control

    Population genomics reveals evolution and variation of Saccharomyces cerevisiae in the human and insects gut

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    The quest to discover the variety of ecological niches inhabited by Saccharomyces cerevisiae has led to research in areas as diverse as wineries, oak trees, and insect guts. The discovery of fungal communities in the human gastrointestinal tract suggested the host's gut as a potential reservoir for yeast adaptation. Here we report the existence of yeast populations associated with the human gut (HG) that differ from those isolated from other human body sites. Phylogenetic analysis on 12 microsatellite loci and 1,715 combined CDSs from whole‐genome sequencing revealed three subclusters of HG strains with further evidence of clonal colonization within the host's gut. The presence of such subclusters was supported by other genomic features, such as copy number variation, absence/introgressions of CDSs and relative polymorphism frequency. Functional analysis of CDSs specific of the different subclusters suggested possible alterations in cell wall composition and sporulation features. The phenotypic analysis combined with immunological profiling of these strains further showed that sporulation was related with strain‐specific genomic characteristics in the immune recognition pattern. We conclude that both genetic and environmental factors involved in cell wall remodeling and sporulation are the main drivers of adaptation in S. cerevisiae populations in the human gut

    Effects of dietary arachidonic acid in European sea bass (Dicentrarchus labrax) distal intestine lipid classes and gut health

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    The use of low fishmeal/fish oil in marine fish diets affects dietary essential fatty acids (EFAs) composition and concentration and, subsequently, may produce a marginal deficiency of those fatty acids with a direct impact on the fish intestinal physiology. Supplementation of essential fatty acids is necessary to cover the requirements of the different EFAs, including the ones belonging to the n-6 series, such as arachidonic acid (ARA). ARA, besides its structural role in the configuration of the lipid classes of the intestine, plays an important role in the functionality of the gut-associated immune tissue (GALT). The present study aimed to test five levels of dietary ARA (ARA0.5 (0.5%), ARA1 (1%), ARA2 (2%), ARA4 (4%), and ARA6 (6%)) for European sea bass (Dicentrarchus labrax) juveniles in order to determine (a) its effect in selected distal intestine (DI) lipid classes composition and (b) how these changes affected gut bacterial translocation rates and selected GALT-related gene expression pre and post challenge. No differences were found between distal intestines of fish fed with the graded ARA levels in total neutral lipids and total polar lipids. However, DI of fish fed with the ARA6 diet presented a higher (P

    Characterization of cervico-vaginal microbiota in women developing persistent high-risk Human Papillomavirus infection

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    Abstract Changes in cervico-vaginal microbiota with Lactobacillus depletion and increased microbial diversity facilitate human papillomavirus (HPV) infection and might be involved in viral persistence and cancer development. To define the microbial Community State Types (CSTs) associated with high-risk HPV−persistence, we analysed 55 cervico-vaginal samples from HPV positive (HPV+) women out of 1029 screened women and performed pyrosequencing of 16S rDNA. A total of 17 samples from age-matched HPV negative (HPV−) women were used as control. Clearance or Persistence groups were defined by recalling women after one year for HPV screening and genotyping. A CST IV subgroup, with bacterial genera such as Gardnerella, Prevotella, Megasphoera, Atopobium, frequently associated with anaerobic consortium in bacterial vaginosis (BV), was present at baseline sampling in 43% of women in Persistence group, and only in 7.4% of women in Clearance group. Atopobium genus was significantly enriched in Persistence group compared to the other groups. Sialidase-encoding gene from Gardnerella vaginalis, involved in biofilm formation, was significantly more represented in Persistence group compared to the other groups. Based on these data, we consider the CST IV-BV as a risk factor for HPV persistence and we propose Atopobium spp and sialidase gene from G. vaginalis as microbial markers of HPV−persistence

    Unravelling the Encapsulation of DNA and Other Biomolecules in HAp Microcalcifications of Human Breast Cancer Tissues by Raman Imaging

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    Microcalcifications are detected through mammography screening and, depending on their morphology and distribution (BI-RADS classification), they can be considered one of the first indicators of suspicious cancer lesions. However, the formation of hydroxyapatite (HAp) calcifications and their relationship with malignancy remains unknown. In this work, we report the most detailed three-dimensional biochemical analysis of breast cancer microcalcifications to date, combining 3D Raman spectroscopy imaging and advanced multivariate analysis in order to investigate in depth the molecular composition of HAp calcifications found in 26 breast cancer tissue biopsies. We demonstrate that DNA has been naturally adsorbed and encapsulated inside HAp microcalcifications. Furthermore, we also show the encapsulation of other relevant biomolecules in HAp calcifications, such as lipids, proteins, cytochrome C and polysaccharides. The demonstration of natural DNA biomineralization, particularly in the tumor microenvironment, represents an unprecedented advance in the field, as it can pave the way to understanding the role of HAp in malignant tissues
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