Propiedades inmuno reguladoras de los linfocitos CD3+CD4-CD8-(doble negativos)

Tesis Univ. Complutense de MadridFac. de MedicinaTRUEpu

Propiedades inmuno reguladoras de los linfocitos CD3+CD4-CD8-(doble negativos)

Tesis Univ. Complutense de MadridFac. de MedicinaTRUEpu

The effects of European recommendations on the validation of lifelong learning: A quality assurance model for VET in Spain

Producción CientíficaValidation is an effective procedure for recognising the skills and knowledge acquired by individuals. However, the validation mechanisms in each country are not always easy to understand, especially due to a lack of information/data. The aim of this paper is to design a management system based on processes for the accreditation of professional competences acquired by work experience in Spain, considering European regulations. This is carried out through a contextualization of both regulatory frameworks through a bibliographic review, as well as the analysis of the quantitative and qualitative outcomes of the surveys that groups of experts involved in these tasks/procedures completed in Spain. All this has made it possible to design a model for the validation of learning acquired through professional experience as well as non-formal and informal channels in Europe and Spain, which facilitates the process of accreditation of competences

International correspondents in Spain facing Government and information sources. Evaluation of problems by analytic hierarchy process (AHP)

Correspondent

A meta-analytical review of the responses in the MMPI-2/MMPI-2-RF clinical and restructured scales of parents in child custody dispute

Parental attribute evaluation in relation to child custody comprises psychological and psychopathology. Additionally, defensiveness must be suspected on this setting. The worldwide reference psychometric measurement instrument for this purpose is the MMPI. With the aim of knowing the responses of parents litigating by child custody, a meta-analytic review of the responses to clinical and restructured scales was performed. A total of 21 primary studies (studies with a simulation design i.e., participants were instructed to answer as parents litigating by child custody were found were disregarded) were found, obtaining 291 effect sizes for clinical scales and 1 for restructured scales. The results showed positive, significant and generalizable mean true effect size in the Hy, Pd and Pa scales; a negative, significant and generalizable in the Ma and Si scales, and non-generalizable in the Pt y Sc scales; and a trivial mean true effect size in the Hs and D scales. Parent gender was studied as a moderator having no found differences between the responses of mothers and fathers. The implications of the results for forensic evaluation practices are discussed.La evaluación de las capacidades parentales para el ejercicio de la guarda y custodia de los hijos incluye el ajuste psicológico y la psicopato-logía. En esta evaluación, además, se ha de sospechar disimulación. El ins-trumento psicométrico de referencia para dicha evaluación es el MMPI. Para conocer de lo informado por los progenitores en disputa por la cus-todia nos planteamos una revisión meta-analítica de las escalas clínicas y las escalas clínicas reestructuradas. Encontramos 21 estudios primarios con progenitores (se descartaron los diseños de simulación de progenitores en disputa) de los que obtuvieron 291 tamaños del efecto para las escalas clí-nicas y 1 para las reestructuradas. Los resultados mostraron un tamaño del efecto promedio positivo, significativo, y generalizable en las escalas Hy, Pd y Pa; negativo, significativo y generalizable en las escalas Ma y Siy no gene-ralizable en las escalas Pty Sc; y un tamaño del efecto promedio insignifi-cante en las escalas Hsy D. Se estudió el género como moderador, no ha-llándose diferencias entre padres y madres. Se discuten las implicaciones de los resultados para la práctica forense.Esta investigación fue financiada, en parte, con un proyecto del Ministerio de Economía y Competitividad de España de refencia PSI2017-87278-RS

Diferencias territoriales en la mortalidad prematura y evitable en España

The study of premature mortality and evitable throw indicator of potential years of live, it lost discover important space differences in Spain, that traduce the uneven geography of the risk factors. In this work it have a first approximation of the thematic, that the end of this is the rules supply of the causes that indicated the lost years of potentials live in a country that like Spain have obtained the last phase of epidemic transition.El estudio de la mortalidad prematura y evitable a través del indicador de años potenciales de vida perdidos descubre importantes diferencias espaciales en España, que traducen la dispar geografía de los factores de riesgo. En este trabajo se hace una primera aproximación a esta temática con el fin de suministrar pautas sobre las causas que más inciden en la pérdida de anos potenciales de vida en un país que como España ha alcanzado la última fase de la transición epidemiológica. [fr] L'étude de la mortalité prématurée et évitable, moyenant l'indicateur d'annés potentielles de vie manquées, met en évidence d'importantes différences territoriales en Espagne, qui font apparaître la dissemblable géographie des facteurs de risque. A cet exposé, on fait une premiere approximation sur ce sujet afín de dournir des regles sur les causes qui ont une plus grande incidence lors de la perte d'annés potentielles de vie das un pays qui, comme l'espagne, a atteint la derniere phase de la transition épidémiologique

The validity and reliability of a new instrumented device for measuring ankle dorsiflexion range of motion

PURPOSE/BACKGROUND: A restriction in ankle dorsiflexion range of motion (ROM) has been linked to several clinical manifestations such as metatarsalgia, heel pain, nerve entrapment, ankle joint equinus, patellar and ankle injuries. The purpose of the present study was to examine the validity and reliability of the Leg Motion system for measuring ankle dorsiflexion ROM. STUDY DESIGN: Descriptive repeated-measures study. METHODS: Twenty-six healthy male university students were recruited to test the reliability of the Leg Motion system, which is a portable tool used for assessment of ankle dorsiflexion during the weight-bearing lunge test. The participants were tested two times separated by two weeks and measurements were performed at the same time of the day by the same single rater. To test the validity of the Leg Motion system, other maximal ankle dorsiflexion ROM assessments (goniometer, inclinometer and measuring tape) were measured in a single session (i.e., the first test session) during the weight-bearing lunge position using a standard goniometer, a digital inclinometer and a measuring tape measure with the ability to measure to the nearest 0.1 cm. RESULTS: Paired t-tests showed the absence of significant differences between right and left limb measurements of dorsiflexion in all tests. Mean values ± standard deviations were as follows: Leg Motion test (left 11.6cm±3.9; right 11.9cm ±4.0), tape measure (left 11.6cm±4.0; right 11.8cm±4.2), goniometer (left 40.6º±5.2; right 40.6º±5.2), and digital inclinometer (left 40.0º±5.8; right 39.9º±5.6). The Leg Motion composite values (i.e., average of the two legs) showed a significant (p<0.05) positive correlation with the tape measure (r=0.99), with the goniometer (r=0.66), and with the digital inclinometer (r=0.72). CONCLUSIONS: The results of the present study provide evidence to support the use of the Leg Motion system as a valid, portable, and easy to use alternative to the weight-bearing lunge test to assess ankle dorsiflexion ROM in healthy participants

Patrimonio académico como herramienta para el desarrollo de futuras carreras científicas

Desde hace tiempo la Unión Europea busca y fomenta la cooperación entre la Universidad y los Institutos de Educación Secundaria para el desarrollo de futuras carreras científicas. Después de varios proyectos de investigación competitivos desarrollados por separado, hemos encontrado importantes confluencias entre el patrimonio custodiado por la Universidad Complutense y el IES San Isidro; ambas instituciones cuentan con una larga historia y atesoran un patrimonio científico, artístico y educativo de gran interés que es necesario conectar y poner en valor. La universidad ha desarrollado varios programas de cooperación en varios niveles y muchas de ellos planteaban mostrar y experimentar con el fin de descubrir, propuesta en la que queremos ahondar y avanzar a través del patrimonio educativo

International correspondents in Spain facing Government and information sources. Evaluation of problems by analytic hierarchy process (AHP)

Correspondents have faced significant changes in the professional model of journalism and the deterioration of the profession due to the effects of the economic crisis in the journalism sector. This article proposes an approach to this reality in Spain, and does so by trying to determine what specific factors make the tasks of correspondents more difficult within the general context of the structural weakening of journalism. The methodology Analytic Hierarchy Process (AHP) is used for this purpose. This methodology is based on the idea that the complexity inherent to an evaluative decision in which multiple factors intertwine can be resolved by quantitatively ranking them, which allows identifying what is truly influential. In this study, a panel of correspondents was interviewed with open questions about hinderances to their work, next their answers were turned into a survey which was administered to the same panel. This led us to determine the relative weight of four challenges: 1. The lack of collaboration by the Government with correspondents; 2. The difficulty in accessing sources; 3. The agenda setting due to the loss of status of correspondents; 4. The clash with Spanish culture

Materials Research for HiPER Laser Fusion Facilities: Chamber Wall, Structural Material and Final Optics.

The European HiPER project aims to demonstrate commercial viability of inertial fusion energy within the following two decades. This goal requires an extensive Research &Development program on materials for different applications (e.g., first wall, structural components and final optics). In this paper we will discuss our activities in the framework of HiPER to develop materials studies for the different areas of interest. The chamber first wall will have to withstand explosions of at least 100 MJ at a repetition rate of 5-10 Hz. If direct drive targets are used, a dry wall chamber operated in vacuum is preferable. In this situation the major threat for the wall stems from ions. For reasonably low chamber radius (5-10 m) new materials based on W and C are being investigated, e.g., engineered surfaces and nanostructured materials. Structural materials will be subject to high fluxes of neutrons leading to deleterious effects, such as, swelling. Low activation advanced steels as well as new nanostructured materials are being investigated. The final optics lenses will not survive the extreme ion irradiation pulses originated in the explosions. Therefore, mitigation strategies are being investigated. In addition, efforts are being carried out in understanding optimized conditions to minimize the loss of optical properties by neutron and gamma irradiatio