Enhancing Education Through Technology: Prinicpal Leadership For Technology Integration In Schools

Principals need to acquire understanding of, and proficiency in, technology skills and integration to be effective instructional leaders. As issues concerning the lack of systemic change in school reform and technology integration persist, little research has been published concerning the extent to which technology leadership behaviors identified in the National Educational Technology Standards for Administrators (NETS-A; International Society for Technology in Education, 2002) are being implemented in schools. The purpose of this study is to analyze the extent to which Michigan elementary principals employ behaviors that support their role as effective technology leaders. Michigan K-6 school principals (n = 280) completed the Survey of Technology Experiences (Billheimer, 2007) developed from the six NETS-A standards (leadership and vision; learning and teaching; productivity and professional practice; support, management, and operations; assessment and evaluation; and social, legal, and ethical issues). Through this quantitative method, the study determined how principals rated the level of importance of the NETS-A and their interest in professional development. Through a qualitative method, this study describes the principal\u27s current practice and implementation of the NETS-A. Ten principals from K-6 schools participated in in-depths interviews of their training and practice for technology leadership. Results concluded that the most important issue in effective technology use in schools is presence of informed and effective principals. Many principals, regardless of the length of time spent in technology-related professional development, participation in on-line courses, or location of the school (urban, rural, suburban), did not feel comfortable with technology and had significant professional development needs as indicated by this study. There also was a need for principals to engage in collaborative networks to enhance their professional practice. Furthermore, consideration to innovative methods of professional development delivery, such as online and distance learning opportunities, need be available. Results of this study can be used to prepare Michigan principals for the emergence of a global society\u27s demand of technology competent principals and to align current perspectives of administrator preparation in regards to technology skills and technology leadership to the NETS-A standards

Stimulation of tPA-dependent provisional extracellular fibrin matrix degradation by human recombinant soluble melanotransferrin

AbstractTissue-type plasminogen activator (tPA) and its substrate plasminogen (Plg) are key components in the fibrinolytic system. We have recently demonstrated, that truncated human recombinant soluble melanotransferrin (sMTf) could stimulate the activation of Plg by urokinase plasminogen activator and inhibit angiogenesis. Since various angiogenesis inhibitors were shown to stimulate tPA-mediated plasminogen activation, we examined the effects of sMTf on tPA-dependent fibrinolysis. This study demonstrated that sMTf enhanced tPA-activation of Plg by 6-fold. sMTf also increased the release of [125I]-fibrin fragments by tPA-activated plasmin. Moreover, we observed that the interaction of sMTf with Plg provoked a change in the fibrin clot structure by cleaving the fibrin α and β chains. Overall, the present study shows that sMTf modulates tPA-dependent fibrinolysis by modifying the clot structure. These results also suggest that sMTf properties could involve enhanced dissolution of the provisional extracellular fibrin matrix

Sexual behaviour and condom use among university students in Madagascar

Although the number of known HIV-infected students in Madagascar increased significantly between 1989 and 1995, very little is known about student behaviour with regard to AIDS. The study objectives were: to describe Malagasy students\' sexual behaviour and condom use; to document students\' perceptions about condoms; and to study the relationships between students\' socio-demographic characteristics, their perceptions about condoms, and their condom use. The survey used a cross-sectional design and was conducted at the Antananarivo\'s university campus sites. Anonymous questionnaires were self-administered to 320 randomly selected students. Descriptive statistics and 95% confidence intervals were calculated. Logistic regressions were performed to identify the predictors of condom use. Participants\' average age was 24 years. Approximately 80% of the participants reported sexual experiences, and the average age at sexual debut was 19 years. Only 5.7% reported consistent condom use. Common reasons for non-use were steady relationships (75.6%), the perception that condoms were useful only during ovulation periods (8.7%), and the decrease of pleasure (6.4%). The predictors of condom use were male gender, and the perception that condoms were useful during ovulation periods. Risky sexual behaviours with regard to AIDS were prevalent in this community. An HIV prevention programme is recommended. Bien que le nombre connu des étudiants malgaches infectés par le VIH ait largement augmenté entre 1989 et 1995, l\'information sur le comportement des étudiants par rapport au SIDA est très limitée. Les objectifs de cette étude furent: 1) décrire le comportement sexuel des étudiants malgaches et l\'utilisation du préservatif, 2) documenter les perceptions des étudiants envers les préservatifs, 3) examiner dans quelle mesure l\'utilisation du préservatif par les étudiants varie en fonction de leurs caractéristiques sociodémographiques et leurs perceptions envers les préservatifs. Cette étude a été menée dans les sites du campus universitaire d\'Antananarivo en utilisant un devis transversal. Un questionnaire anonyme a été auto-administré à 320 étudiants sélectionnés au hasard. Des statistiques descriptives et intervalles de confiance à 95% ont été calculés. La régression logistique a été utilisée pour identifier les déterminants de l\'utilisation du préservatif. La moyenne d\'âge des participants était de 24 ans. Environ 80% des répondants ont signalé avoir eu des rapports sexuels et l\'âge moyen de premiers rapports était de 19 ans. Seulement 5,7% ont rapporté l\'utilisation systématique du préservatif. Les raisons de non utilisation furent les suivantes : être dans une relation stable (75,6%), la perception que le préservatif est uniquement utile durant la période d\'ovulation (8,7%) et la réduction du plaisir (6,4%). Le genre masculin et l\'argument d\'ovulation ont été identifiés comme prédicteurs d\'utilisation de préservatifs. Les comportements sexuels à risque vis-à-vis du SIDA étaient prédominants dans cette communauté. Un programme de prévention du VIH est recommandé. Keywords: Sexual behaviour, condoms, HIV, students, Madagascar. SAHARA J Vol. 5 (1) 2008: pp. 28-3

Salmonella genomic island 1 (SGI1) reshapes the mating apparatus of IncC conjugative plasmids to promote self-propagation.

IncC conjugative plasmids and Salmonella genomic island 1 (SGI1) and relatives are frequently associated with multidrug resistance of clinical isolates of pathogenic Enterobacteriaceae. SGI1 is specifically mobilized in trans by IncA and IncC plasmids (commonly referred to as A/C plasmids) following its excision from the chromosome, an event triggered by the transcriptional activator complex AcaCD encoded by these helper plasmids. Although SGI1 is not self-transmissible, it carries three genes, traNS, traHS and traGS, coding for distant homologs of the predicted mating pore subunits TraNC, TraHC and TraGC, respectively, encoded by A/C plasmids. Here we investigated the regulation of traNS and traHGS and the role of these three genes in the transmissibility of SGI1. Transcriptional fusion of the promoter sequences of traNS and traHGS to the reporter gene lacZ confirmed that expression of these genes is inducible by AcaCD. Mating experiments using combinations of deletion mutants of SGI1 and the helper IncC plasmid pVCR94 revealed complex interactions between these two mobile genetic elements. Whereas traNC and traHGC are essential for IncC plasmid transfer, SGI1 could rescue null mutants of each individual gene revealing that TraNS, TraHS and TraGS are functional proteins. Complementation assays of individual traC and traS mutants showed that not only do TraNS/HS/GS replace TraNC/HC/GC in the mating pore encoded by IncC plasmids but also that traGS and traHS are both required for SGI1 optimal transfer. In fact, remodeling of the IncC-encoded mating pore by SGI1 was found to be essential to enhance transfer rate of SGI1 over the helper plasmid. Furthermore, traGS was found to be crucial to allow DNA transfer between cells bearing IncC helper plasmids, thereby suggesting that by remodeling the mating pore SGI1 disables an IncC-encoded entry exclusion mechanism. Hence traS genes facilitate the invasion by SGI1 of cell populations bearing IncC plasmids

ICIS 2011 Panel Report: Are We on the Wrong Track and Do MIS Curricula Need to Be Reengineered?

The discipline of MIS has been going through extensive soul searching in recent years. Part of that soul searching deals with the question of whether we are teaching our students the right material considering the emerging apparent rift, caused in part by new technologies, between what the industry needs and what we teach. This article summarizes a panel on this topic held at the 32nd meeting of the International Conference on Information Systems (ICIS) in Shanghai 2011. The objective of the panel was to contrast what industry tells us they need and we do not give them, as presented by Gefen and Ragowsky based on several years of CIO roundtables and interviews, with a “balanced head” perspective presented by some of the most respected leaders in our field. The panel attracted an audience of approximately 160 attendees who took an active role in the discussion. Rather surprisingly, disagreements among the panelists were not as pronounced as might have been expected, and the audience mostly supported the antagonist position. We present this summary to our colleagues in MIS in the hope of eliciting a continued discussion on this crucial issue

Exploration and comparison of methods for combining population- and family-based genetic association using the Genetic Analysis Workshop 17 mini-exome

We examine the performance of various methods for combining family- and population-based genetic association data. Several approaches have been proposed for situations in which information is collected from both a subset of unrelated subjects and a subset of family members. Analyzing these samples separately is known to be inefficient, and it is important to determine the scenarios for which differing methods perform well. Others have investigated this question; however, no extensive simulations have been conducted, nor have these methods been applied to mini-exome-style data such as that provided by Genetic Analysis Workshop 17. We quantify the empirical power and false-positive rates for three existing methods applied to the Genetic Analysis Workshop 17 mini-exome data and compare relative performance. We use knowledge of the underlying data simulation model to make these assessments

The interaction of lean and building information modeling in construction

Lean construction and Building Information Modeling are quite different initiatives, but both are having profound impacts on the construction industry. A rigorous analysis of the myriad specific interactions between them indicates that a synergy exists which, if properly understood in theoretical terms, can be exploited to improve construction processes beyond the degree to which it might be improved by application of either of these paradigms independently. Using a matrix that juxtaposes BIM functionalities with prescriptive lean construction principles, fifty-six interactions have been identified, all but four of which represent constructive interaction. Although evidence for the majority of these has been found, the matrix is not considered complete, but rather a framework for research to explore the degree of validity of the interactions. Construction executives, managers, designers and developers of IT systems for construction can also benefit from the framework as an aid to recognizing the potential synergies when planning their lean and BIM adoption strategies

Scaling-up beginning farmers for wholesale production

With nearly 15 million people that live within 250 miles of Kansas City, the demand for local food is increasing. Local beginning farmers in the region want to reach an emerging wholesale market. However, selling directly to consumers demands different skills than the wholesale market requires. There are many educational programs offered in the region that are focused on direct to consumer sales. Unfortunately, there is a gap in educational programs that are offered to support beginning farmers that wish to expand into wholesale markets. In 2018, the Beginning Farmer Wholesale Project was started within the Growing Growers Kansas City program in congruence with the overall mission to improve the skills and livelihoods of the region’s growers. The project offers support and training to beginning farmers as they begin to navigate new market opportunities. It provides on-farm technical assistance, mentorship, opportunities to connect to wholesale buyers, a workshop series, a manual and an extensive foodshed GIS map. The ongoing project has seen several contributions to improving farmer access to wholesale markets. As of 2020, six workshops have been conducted that have covered a variety of farm production and marketing skills. Six farmer mentees have enrolled in the mentor program which enlists nine farmer mentors from across the region. Over twenty farmers have utilized the technical assistance service on their Kansas and Missouri farm operations and the farmer buyer matching program has resulted in thirteen beginning farmers gaining access to new markets. The project highlights the value of collaboration among organizations and the importance of offering multiple farmer services in order to improve wholesale access

Definition of medical event is to be based on the total source strength for evaluation of permanent prostate brachytherapy: A report from the American Society for Radiation Oncology

AbstractPurposeThe Nuclear Regulatory Commission deems it to be a medical event (ME) if the total dose delivered differs from the prescribed dose by 20% or more. A dose-based definition of ME is not appropriate for permanent prostate brachytherapy as it generates too many spurious MEs and thereby creates unnecessary apprehension in patients, and ties up regulatory bodies and the licensees in unnecessary and burdensome investigations. A more suitable definition of ME is required for permanent prostate brachytherapy.Methods and MaterialsThe American Society for Radiation Oncology (ASTRO) formed a working group of experienced clinicians to review the literature, assess the validity of current regulations, and make specific recommendations about the definition of an ME in permanent prostate brachytherapy.ResultsThe working group found that the current definition of ME in §35.3045 as “the total dose delivered differs from the prescribed dose by 20 percent or more” was not suitable for permanent prostate brachytherapy since the prostate volume (and hence the resultant calculated prostate dose) is dependent on the timing of the imaging, the imaging modality used, the observer variability in prostate contouring, the planning margins used, inadequacies of brachytherapy treatment planning systems to calculate tissue doses, and seed migration within and outside the prostate. If a dose-based definition for permanent implants is applied strictly, many properly executed implants would be improperly classified as an ME leading to a detrimental effect on brachytherapy. The working group found that a source strength-based criterion, of >20% of source strength prescribed in the post-procedure written directive being implanted outside the planning target volume is more appropriate for defining ME in permanent prostate brachytherapy.ConclusionsASTRO recommends that the definition of ME for permanent prostate brachytherapy should not be dose based but should be based upon the source strength (air-kerma strength) administered

The enhanced cognitive interview: expressions of uncertainty, motivation and its relation with report accuracy

The Enhanced Cognitive Interview (ECI) is one of the most widely studied and used methods to interview witnesses. However, ECI research has mainly focused on increasing report size and somewhat overlooked how to improve and evaluate report accuracy. No study evaluated if witnesses’ spontaneous expressions of uncertainty are accurate metacognitive judgments, nor if witnesses’ motivation during the interview affects report accuracy. This study examined how witnesses’ judgments of recall ‘uncertainty’ and their motivation perception could relate to report accuracy. Forty-four psychology students watched a mock robbery video recording and were interviewed 48 hours later with either the Portuguese version of the ECI or a Structured Interview (SI). Afterward, participants’ motivation was assessed and items of information were classified as ‘certainties’ or ‘uncertainties’. Results suggest that our ECI protocol was effective, since participants interviewed with the ECI produced more information without compromising accuracy. ‘Uncertainties’ were less accurate than ‘certainties’, and their exclusion raised overall, ECI, and SI, accuracy. More motivated participants had better recall accuracy. Accounting for witnesses’ motivation and spontaneous verbal expressions of uncertainty may be effective and time-saving procedures to increase accuracy. These are key points that professionals and researchers should consider