311 research outputs found
Effects of drought on avian community structure
Droughts are expected to become more frequent under global climate change. Avifauna depend on precipitation for hydration, cover, and food. While there are indications that avian communities respond negatively to drought, little is known about the response of birds with differing functional and behavioral traits, what time periods and indicators of drought are most relevant, or how response varies geographically at broad spatial scales. Our goals were thus to determine (1) how avian abundance and species richness are related to drought, (2) whether community variations are more related to vegetation vigor or precipitation deviations and at what time periods relationships were strongest, (3) how response varies among avian guilds, and (4) how response varies among ecoregions with different precipitation regimes. Using mixed effect models and 1989–2005 North American Breeding Bird Survey data over the central United States, we examined the response to 10 precipitation- and greenness based metrics by abundance and species richness of the avian community overall, and of four behavioral guilds. Drought was associated with the most negative impacts on avifauna in the semiarid Great Plains, while positive responses were observed in montane areas. Our models predict that in the plains, Neotropical migrants respond the most negatively to extreme drought, decreasing by 13.2% and 6.0% in abundance and richness, while permanent resident abundance and richness increase by 11.5% and 3.6%, respectively in montane areas. In most cases, response of abundance was greater than richness and models based on precipitation metrics spanning 32-week time periods were more supported than those covering shorter time periods and those based on greenness. While drought is but one of myriad environmental variations birds encounter, our results indicate that drought is capable of imposing sizable shifts in abundance, richness, and composition on avian communities, an important implication of a more climatically variable future
Combined effects of heat waves and droughts on avian communities across the conterminous United States
Increasing surface temperatures and climatic variability associated with global climate change are expected to produce more frequent and intense heat waves and droughts in many parts of the world. Our goal was to elucidate the fundamental, but poorly understood, effects of these extreme weather events on avian communities across the conterminous United States. Specifically, we explored: (1) the effects of timing and duration of heat and drought events, (2) the effects of jointly occurring drought and heat waves relative to these events occurring in isolation, and (3) how effects vary among functional groups related to nest location and migratory habit, and among ecoregions with differing precipitation and temperature regimes. Using data from remote sensing, meteorological stations, and the North American Breeding Bird Survey, we used mixed effects models to quantify responses of overall and functional group abundance to heat waves and droughts (occurring alone or in concert) at two key periods in the annual cycle of birds: breeding and post-fledging. We also compared responses among species with different migratory and nesting characteristics, and among 17 ecoregions of the conterminous United States. We found large changes in avian abundances related to 100-year extreme weather events occurring in both breeding and post-fledging periods, but little support for an interaction among time periods. We also found that jointly-, rather than individually-occurring heat waves and droughts were both more common and more predictive of abundance changes. Declining abundance was the only significant response to post-fledging events, while responses to breeding period events were larger but could be positive or negative. Negative responses were especially frequent in the western U.S., and among ground-nesting birds and Neotropical migrants, with the largest single-season declines (36%) occurring among ground-nesting birds in the desert Southwest. These results indicate the importance of functional traits, timing, and geography in determining avian responses to weather extremes. Because dispersal to other regions appears to be an important avian response, it may be essential to maintain habitat refugia in a more climatically variable future
The spontaneous release of a high-molecular-weight aggregate containing immunoglobulin G from the surface of Ehrlich ascites tumor cells
The spontaneous release of tumor cell antigens from the cell surface into the circulation has been proposed as a mechanism whereby tumors may escape the immune response of the host. In this study we have found that Ehrlich ascites tumor cells after removal from the host (mouse) spontaneously release significant amounts of cell surface components during incubation for 1 h in cold isotonic buffer. Immunodiffusion studies revealed that immunoglobulin G (IgG) and a complement component (C3) are included in this spontaneously released material. These surface-bound humoral immune components are apparently released in the form of a high-molecular-weight aggregate (cell coat particle) as shown by ultracentrifugation and ultrafiltration experiments. Precipitation of IgG from the cell coat particle preparation with antibodies directed against mouse IgG followed by detergent gel electrophoresis of the immune precipitate revealed five major bands in addition to the heavy and light chains of IgG. These results suggest that host IgG is tightly bound to several other components at the cell surface, perhaps in the form of immune complexes. IgG is localized on the tumor cell surface in a highly heterogeneous pattern with the appearance of patches and caps in some cells as shown by immuno-fluorescence analysis. The possibility that humoral immune components bind to the tumor cell surface and result in the shedding of high-molecular-weight aggregates of cell surface antigens into extracellular fluids is discussed.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/38207/1/400090311_ftp.pd
Impact of Baseline Retinal Nonperfusion and Macular Retinal Capillary Nonperfusion on Outcomes in the COPERNICUS and GALILEO Studies
To evaluate the impact of baseline retinal capillary nonperfusion (RNP) and macular retinal capillary nonperfusion (MNP) status on outcomes at week 24 (W24)
Stability of Inhomogeneous Multi-Component Fermi Gases
Two-component equal-mass Fermi gases, in which unlike atoms interact through
a short-range two-body potential and like atoms do not interact, are stable
even when the interspecies s-wave scattering length becomes infinitely large.
Solving the many-body Schroedinger equation within a hyperspherical framework
and by Monte Carlo techniques, this paper investigates how the properties of
trapped two-component gases change if a third or fourth component are added. If
all interspecies scattering lengths are equal and negative, our calculations
suggest that both three- and four-component Fermi gases become unstable for a
certain critical set of parameters. The relevant length scale associated with
the collapse is set by the interspecies scattering length and we argue that the
collapse is, similar to the collapse of an attractive trapped Bose gas, a
many-body phenomenon. Furthermore, we consider a three-component Fermi gas in
which two interspecies scattering lengths are negative while the other
interspecies scattering length is zero. In this case, the stability of the
Fermi system is predicted to depend appreciably on the range of the underlying
two-body potential. We find parameter combinations for which the system appears
to become unstable for a finite negative scattering length and parameter
combinations for which the system appears to be made up of weakly-bound trimers
that consist of one fermion of each species.Comment: 15 pages, 8 figure
A general T-matrix approach applied to two-body and three-body problems in cold atomic gases
We propose a systematic T-matrix approach to solve few-body problems with
s-wave contact interactions in ultracold atomic gases. The problem is generally
reduced to a matrix equation expanded by a set of orthogonal molecular states,
describing external center-of-mass motions of pairs of interacting particles;
while each matrix element is guaranteed to be finite by a proper
renormalization for internal relative motions. This approach is able to
incorporate various scattering problems and the calculations of related
physical quantities in a single framework, and also provides a physically
transparent way to understand the mechanism of resonance scattering. For
applications, we study two-body effective scattering in 2D-3D mixed dimensions,
where the resonance position and width are determined with high precision from
only a few number of matrix elements. We also study three fermions in a
(rotating) harmonic trap, where exotic scattering properties in terms of mass
ratios and angular momenta are uniquely identified in the framework of
T-matrix.Comment: 14 pages, 4 figure
Effects of Timber Harvest on Amphibian Populations: Understanding Mechanisms from Forest Experiments
Accompanying appendix may be accessed at: http://hdl.handle.net/10355/1365Harvesting timber is a common form of land use that has the potential to cause declines in amphibian populations. It is essential to understand the behavior and fate of individuals and the resulting consequences for vital rates (birth, death, immigration, emigration) under different forest management conditions.We report on experimental studies conducted in three regions of the United States to identify mechanisms of responses by pond-breeding amphibians to timber harvest treatments. Our studies demonstrate that life stages related to oviposition and larval performance in
the aquatic stage are sometimes affected positively by clearcutting, whereas effects on juvenile and adult terrestrial stages are mostly negative
The Hyperspherical Four-Fermion Problem
The problem of a few interacting fermions in quantum physics has sparked
intense interest, particularly in recent years owing to connections with the
behavior of superconductors, fermionic superfluids, and finite nuclei. This
review addresses recent developments in the theoretical description of four
fermions having finite-range interactions, stressing insights that have emerged
from a hyperspherical coordinate perspective. The subject is complicated, so we
have included many detailed formulas that will hopefully make these methods
accessible to others interested in using them. The universality regime, where
the dominant length scale in the problem is the two-body scattering length, is
particularly stressed, including its implications for the famous BCS-BEC
crossover problem Derivations and relevant formulas are also included for the
calculation of challenging few-body processes such as recombination.Comment: 66 pages, 33 figure
Deep saltwater in Chalk of North-West Europe: origin, interface characteristics and development over geological time
Differentiation enhances aminolevulinic acid-dependent photodynamic treatment of LNCaP prostate cancer cells
Photodynamic therapy using 5-aminolevulinic acid (ALA)-induced protoporphyrin IX (PpIX) may be applied to the treatment of neoplasms in a variety of organs. In order to enhance existing regimens of photodynamic therapy, we investigated the effects of adding differentiation therapy to photodynamic therapy in human prostate cancer cells in vitro. The objective of differentiation therapy per se is to reverse the lack of differentiation in cancer cells using pharmacological agents. The motivation for this study was to exploit the differentiation-dependent expression of some heme enzymes to enhance tumour cell toxicity of ALA-photodynamic therapy. A short course of differentiation therapy was applied to increase PpIX formation during subsequent ALA exposure. Using the synthetic androgen R1881, isomers of retinoic acid, and analogues of vitamin D for 3 to 4 days, exogenous ALA-dependent PpIX formation in LNCaP cells was increased, along with markers for growth arrest and for differentiation. As a consequence of higher PpIX levels, cytotoxic effects of visible light exposure were also enhanced. Short-term differentiation therapy increased not only the overall PpIX production but also reduced that fraction of cells that contained low PpIX levels as demonstrated by flow cytometry and fluorescence microscopy. This study suggests that it will be feasible to develop protocols combining short-term differentiation therapy with photodynamic therapy for enhanced photosensitisation
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