5,600 research outputs found
Transferring orbital and spin angular momenta of light to atoms
Light beams carrying orbital angular momentum, such as Laguerre-Gaussian
beams, give rise to the violation of the standard dipolar selection rules
during the interaction with matter yielding, in general, an exchange of angular
momentum larger than hbar per absorbed photon. By means of ab initio 3D
numerical simulations, we investigate in detail the interaction of a hydrogen
atom with intense Gaussian and Laguerre-Gaussian light pulses. We analyze the
dependence of the angular momentum exchange with the polarization, the orbital
angular momentum, and the carrier-envelope phase of light, as well as with the
relative position between the atom and the light vortex. In addition, a
quantum-trajectory approach based on the de Broglie-Bohm formulation of quantum
mechanics is used to gain physical insight into the absorption of angular
momentum by the hydrogen atom
SQG-Differential Evolution for difficult optimization problems under a tight function evaluation budget
In the context of industrial engineering, it is important to integrate
efficient computational optimization methods in the product development
process. Some of the most challenging simulation-based engineering design
optimization problems are characterized by: a large number of design variables,
the absence of analytical gradients, highly non-linear objectives and a limited
function evaluation budget. Although a huge variety of different optimization
algorithms is available, the development and selection of efficient algorithms
for problems with these industrial relevant characteristics, remains a
challenge. In this communication, a hybrid variant of Differential Evolution
(DE) is introduced which combines aspects of Stochastic Quasi-Gradient (SQG)
methods within the framework of DE, in order to improve optimization efficiency
on problems with the previously mentioned characteristics. The performance of
the resulting derivative-free algorithm is compared with other state-of-the-art
DE variants on 25 commonly used benchmark functions, under tight function
evaluation budget constraints of 1000 evaluations. The experimental results
indicate that the new algorithm performs excellent on the 'difficult' (high
dimensional, multi-modal, inseparable) test functions. The operations used in
the proposed mutation scheme, are computationally inexpensive, and can be
easily implemented in existing differential evolution variants or other
population-based optimization algorithms by a few lines of program code as an
non-invasive optional setting. Besides the applicability of the presented
algorithm by itself, the described concepts can serve as a useful and
interesting addition to the algorithmic operators in the frameworks of
heuristics and evolutionary optimization and computing
Structural efficiency of percolation landscapes in flow networks
Complex networks characterized by global transport processes rely on the
presence of directed paths from input to output nodes and edges, which organize
in characteristic linked components. The analysis of such network-spanning
structures in the framework of percolation theory, and in particular the key
role of edge interfaces bridging the communication between core and periphery,
allow us to shed light on the structural properties of real and theoretical
flow networks, and to define criteria and quantities to characterize their
efficiency at the interplay between structure and functionality. In particular,
it is possible to assess that an optimal flow network should look like a "hairy
ball", so to minimize bottleneck effects and the sensitivity to failures.
Moreover, the thorough analysis of two real networks, the Internet
customer-provider set of relationships at the autonomous system level and the
nervous system of the worm Caenorhabditis elegans --that have been shaped by
very different dynamics and in very different time-scales--, reveals that
whereas biological evolution has selected a structure close to the optimal
layout, market competition does not necessarily tend toward the most customer
efficient architecture.Comment: 8 pages, 5 figure
Silencing Early Viral Replication in Macrophages and Dendritic Cells Effectively Suppresses Flavivirus Encephalitis
West Nile (WN) and St. Louis encephalitis (SLE) viruses can cause fatal
neurological infection and currently there is neither a specific treatment nor
an approved vaccine for these infections. In our earlier studies, we have
reported that siRNAs can be developed as broad-spectrum antivirals for the
treatment of infection caused by related viruses and that a small peptide called
RVG-9R can deliver siRNA to neuronal cells as well as macrophages. To increase
the repertoire of broad-spectrum antiflaviviral siRNAs, we screened 25 siRNAs
targeting conserved regions in the viral genome. Five siRNAs were found to
inhibit both WNV and SLE replication in vitro reflecting broad-spectrum
antiviral activity and one of these was also validated in vivo. In addition, we
also show that RVG-9R delivers siRNA to macrophages and dendritic cells,
resulting in effective suppression of virus replication. Mice were challenged
intraperitoneally (i.p.) with West Nile virus (WNV) and treated i.v. with
siRNA/peptide complex. The peritoneal macrophages isolated on day 3 post
infection were isolated and transferred to new hosts. Mice receiving macrophages
from the anti-viral siRNA treated mice failed to develop any disease while the
control mice transferred with irrelevant siRNA treated mice all died of
encephalitis. These studies suggest that early suppression of viral replication
in macrophages and dendritic cells by RVG-9R-mediated siRNA delivery is key to
preventing the development of a fatal neurological disease
Analytical Bethe Ansatz for closed and open gl(n)-spin chains in any representation
We present an "algebraic treatment" of the analytical Bethe Ansatz. For this
purpose, we introduce abstract monodromy and transfer matrices which provide an
algebraic framework for the analytical Bethe Ansatz. It allows us to deal with
a generic gl(n)-spin chain possessing on each site an arbitrary
gl(n)-representation. For open spin chains, we use the classification of the
reflection matrices to treat all the diagonal boundary cases. As a result, we
obtain the Bethe equations in their full generality for closed and open spin
chains. The classifications of finite dimensional irreducible representations
for the Yangian (closed spin chains) and for the reflection algebras (open spin
chains) are directly linked to the calculation of the transfer matrix
eigenvalues. As examples, we recover the usual closed and open spin chains, we
treat the alternating spin chains and the closed spin chain with impurity
High rate, fast timing Glass RPC for the high {\eta} CMS muon detectors
The HL-LHC phase is designed to increase by an order of magnitude the amount
of data to be collected by the LHC experiments. To achieve this goal in a
reasonable time scale the instantaneous luminosity would also increase by an
order of magnitude up to . The region of the forward
muon spectrometer () is not equipped with RPC stations. The
increase of the expected particles rate up to (including a
safety factor 3) motivates the installation of RPC chambers to guarantee
redundancy with the CSC chambers already present. The actual RPC technology of
CMS cannot sustain the expected background level. The new technology that will
be chosen should have a high rate capability and provides a good spatial and
timing resolution. A new generation of Glass-RPC (GRPC) using low-resistivity
(LR) glass is proposed to equip at least the two most far away of the four high
muon stations of CMS. First the design of small size prototypes and
studies of their performance in high-rate particles flux is presented. Then the
proposed designs for large size chambers and their fast-timing electronic
readout are examined and preliminary results are provided.Comment: 14 pages, 11 figures, Conference proceeding for the 2016 Resistive
Plate Chambers and Related Detector
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Measurements of differential and double-differential Drell-Yan cross sections in proton-proton collisions at [Formula: see text][Formula: see text].
Measurements of the differential and double-differential Drell-Yan cross sections in the dielectron and dimuon channels are presented. They are based on proton-proton collision data at [Formula: see text] recorded with the CMS detector at the LHC and corresponding to an integrated luminosity of 19.7[Formula: see text]. The measured inclusive cross section in the [Formula: see text] peak region (60-120[Formula: see text]), obtained from the combination of the dielectron and dimuon channels, is [Formula: see text], where the statistical uncertainty is negligible. The differential cross section [Formula: see text] in the dilepton mass range 15-2000[Formula: see text] is measured and corrected to the full phase space. The double-differential cross section [Formula: see text] is also measured over the mass range 20 to 1500[Formula: see text] and absolute dilepton rapidity from 0 to 2.4. In addition, the ratios of the normalized differential cross sections measured at [Formula: see text] and 8[Formula: see text] are presented. These measurements are compared to the predictions of perturbative QCD at next-to-leading and next-to-next-to-leading (NNLO) orders using various sets of parton distribution functions (PDFs). The results agree with the NNLO theoretical predictions computed with fewz 3.1 using the CT10 NNLO and NNPDF2.1 NNLO PDFs. The measured double-differential cross section and ratio of normalized differential cross sections are sufficiently precise to constrain the proton PDFs
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Search for decays of stopped long-lived particles produced in proton-proton collisions at [Formula: see text].
A search has been performed for long-lived particles that could have come to rest within the CMS detector, using the time intervals between LHC beam crossings. The existence of such particles could be deduced from observation of their decays via energy deposits in the CMS calorimeter appearing at times that are well separated from any proton-proton collisions. Using a data set corresponding to an integrated luminosity of 18.6[Formula: see text] of 8[Formula: see text] proton-proton collisions, and a search interval corresponding to 281 h of trigger livetime, 10 events are observed, with a background prediction of [Formula: see text] events. Limits are presented at 95 % confidence level on gluino and top squark production, for over 13 orders of magnitude in the mean proper lifetime of the stopped particle. Assuming a cloud model of R-hadron interactions, a gluino with mass [Formula: see text]1000[Formula: see text] and a top squark with mass [Formula: see text]525[Formula: see text] are excluded, for lifetimes between 1 [Formula: see text]s and 1000[Formula: see text]. These results are the most stringent constraints on stopped particles to date
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Measurement of the [Formula: see text] production cross section in the all-jets final state in pp collisions at [Formula: see text][Formula: see text].
The cross section for [Formula: see text] production in the all-jets final state is measured in pp collisions at a centre-of-mass energy of 8 [Formula: see text] at the LHC with the CMS detector, in data corresponding to an integrated luminosity of 18.4 [Formula: see text]. The inclusive cross section is found to be [Formula: see text] [Formula: see text]. The normalized differential cross sections are measured as a function of the top quark transverse momenta, [Formula: see text], and compared to predictions from quantum chromodynamics. The results are reported at detector, parton, and particle levels. In all cases, the measured top quark [Formula: see text] spectra are significantly softer than theoretical predictions
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