Elderly day care centers: Recommendations for improvement

Indexación: Scopus.Introduction: Chile has become a country that continues to grow at an accelerated pace. One of the key pieces of the Comprehensive Policy for Positive Aging for Chile is the development of Day Centers for the Elderly (CDPM) directed elderly at the foot of the dependency. Objective: To know the perception of a group of PMs, their caregivers and professionals of their participation in the CDPM with the purpose of designing recommendations to improve this new type of geriatric service established in the country. Methodology: Qualitative descriptive study performed in 30 participants through 4 focus groups: 2 in elderly (n=12), 1 with caregivers (n=8) and 1 with center professionals (n=10). Results: Two main comprehensive categories were identified: 1) Perception of benefits for elderly: improvement of functionality, increase of well-being and insertion of the social mayor, 2) Recommendations for improvement of CDPM: Criteria for inclusive income, flexibility and diversity in activities stipulated and Improvements in egress. Conclusions: The elderly, their caregivers and the professionals who attend them are consistent in pointing out that elderly assistance to this type of service reports benefits in its functionality, well-being and social insertion. This study contributes to broadening the understanding of results in the uses of CDPM by reporting an experience in a particular social context. © 2018 Spanish Publishers Associate. All rights reserved.Introduction: Chile has become a country that continues to grow at an accelerated pace. One of the key pieces of the Comprehensive Policy for Positive Aging for Chile is the development of Day Centers for the Elderly (CDPM) directed elderly at the foot of the dependency. Objective: To know the perception of a group of PMs, their caregivers and professionals of their participation in the CDPM with the purpose of designing recommendations to improve this new type of geriatric service established in the country. Methodology: Qualitative descriptive study performed in 30 participants through 4 focus groups: 2 in elderly (n=12), 1 with caregivers (n=8) and 1 with center professionals (n=10). Results: Two main comprehensive categories were identified: 1) Perception of benefits for elderly: improvement of functionality, increase of well-being and insertion of the social mayor, 2) Recommendations for improvement of CDPM: Criteria for inclusive income, flexibility and diversity in activities stipulated and Improvements in egress. Conclusions: The elderly, their caregivers and the professionals who attend them are consistent in pointing out that elderly assistance to this type of service reports benefits in its functionality, well-being and social insertion. This study contributes to broadening the understanding of results in the uses of CDPM by reporting an experience in a particular social context.http://www.gerokomos.com/wp-content/uploads/2018/03/29-1-2018-009.pd

Astrometry of OH/IR stars using 1612 MHz hydroxyl masers. I. Annual parallaxes of WX Psc and OH138.0+7.2

We report on the measurement of the trigonometric parallaxes of 1612 MHz hydroxyl masers around two asymptotic giant branch stars, WX Psc and OH138.0+7.2, using the NRAO Very Long Baseline Array with in-beam phase referencing calibration. We obtained a 3-sigma upper limit of <=5.3 mas on the parallax of WX Psc, corresponding to a lower limit distance estimate of >~190 pc. The obtained parallax of OH138.0+7.2 is 0.52+/-0.09 mas (+/-18%), corresponding to a distance of 1.9(+0.4,-0.3) kpc, making this the first hydroxyl maser parallax below one milliarcsecond. We also introduce a new method of error analysis for detecting systematic errors in the astrometry. Finally, we compare our trigonometric distances to published phase-lag distances toward these stars and find a good agreement between the two methods.Comment: Preprint, accepted for publication in The Astronomical Journal (January 17, 2017

Functional proteomics outlines the complexity of breast cancer molecular subtypes

Breast cancer is a heterogeneous disease comprising a variety of entities with various genetic backgrounds. Estrogen receptor-positive, human epidermal growth factor receptor 2-negative tumors typically have a favorable outcome; however, some patients eventually relapse, which suggests some heterogeneity within this category. In the present study, we used proteomics and miRNA profiling techniques to characterize a set of 102 either estrogen receptor-positive (ER+)/progesterone receptorpositive (PR+) or triple-negative formalin-fixed, paraffin-embedded breast tumors. Protein expressionbased probabilistic graphical models and flux balance analyses revealed that some ER+/PR+ samples had a protein expression profile similar to that of triple-negative samples and had a clinical outcome similar to those with triple-negative disease. This probabilistic graphical model-based classification had prognostic value in patients with luminal A breast cancer. This prognostic information was independent of that provided by standard genomic tests for breast cancer, such as MammaPrint, OncoType Dx and the 8-gene Score

The VSOP 5 GHz Active Galactic Nucleus Survey. V. Imaging Results for the Remaining 140

In 1997 February, the Japanese radio astronomy satellite HALCA was launched to provide the space-bourne element for the VLBI Space Observatory Program (VSOP) mission. Approximately 25% of the mission time was dedicated to the VSOP survey of bright compact active galactic nuclei (AGNs) at 5 GHz. This paper, the fifth in the series, presents images and models for the remaining 140 sources not included in the third paper in the series, which contained 102 sources. For most sources, the plots of the (u,v) coverage, the visibility amplitude versus (u,v) distance, and the high-resolution image are presented. Model fit parameters to the major radio components are determined, and the brightness temperature of the core component for each source is calculated. The brightness temperature distributions for all of the sources in the VSOP AGN survey are discussed

Key Science Goals for the Next-Generation Event Horizon Telescope

The Event Horizon Telescope (EHT) has led to the first images of a supermassive black hole, revealing the central compact objects in the elliptical galaxy M87 and the Milky Way. Proposed upgrades to this array through the next-generation EHT (ngEHT) program would sharply improve the angular resolution, dynamic range, and temporal coverage of the existing EHT observations. These improvements will uniquely enable a wealth of transformative new discoveries related to black hole science, extending from event-horizon-scale studies of strong gravity to studies of explosive transients to the cosmological growth and influence of supermassive black holes. Here, we present the key science goals for the ngEHT and their associated instrument requirements, both of which have been formulated through a multi-year international effort involving hundreds of scientists worldwide

Anti-inflammatory effect of bee pollen ethanol extract from Cistus sp. of Spanish on carrageenan-induced rat hind paw edema

<p>Abstract</p> <p>Background</p> <p>Bee pollen, a honeybee product, is the feed for honeybees prepared themselves by pollens collecting from plants and has been consumed as a perfect food in Europe, because it is nutritionally well balanced. In this study, we aimed to investigate the anti-inflammatory effect of bee pollen from <it>Cistus </it>sp. of Spanish origin by a method of carrageenan-induced paw edema in rats, and to investigate the mechanism of anti-inflammatory action and also to elucidate components involved in bee pollen extracted with ethanol.</p> <p>Methods</p> <p>The bee pollen bulk, its water extract and its ethanol extract were administered orally to rats. One hour later, paw edema was produced by injecting of 1% solution of carrageenan, and paw volume was measured before and after carrageenan injection up to 5 h. The ethanol extract and water extract were measured COX-1 and COX-2 inhibitory activities using COX inhibitor screening assay kit, and were compared for the inhibition of NO production in LPS-stimulated RAW 264.7 cells. The constituents of bee pollen were purified from the ethanol extract subjected to silica gel or LH-20 column chromatography. Each column chromatography fractions were further purified by repeated ODS or silica gel column chromatography.</p> <p>Results</p> <p>The bee pollen bulk mildly suppressed the carrageenan-induced paw edema and the water extract showed almost no inhibitory activity, but the ethanol extract showed relatively strong inhibition of paw edema. The ethanol extract inhibited the NO production and COX-2 but not COX-1 activity, but the water extract did not affect the NO production or COX activities. Flavonoids were isolated and purified from the ethanol extract of bee pollen, and identified at least five flavonoids and their glycosides.</p> <p>Conclusions</p> <p>It is suggested that the ethanol extract of bee pollen show a potent anti-inflammatory activity and its effect acts <it>via </it>the inhibition of NO production, besides the inhibitory activity of COX-2. Some flavonoids included in bee pollen may partly participate in some of the anti-inflammatory action. The bee pollen would be beneficial not only as a dietary supplement but also as a functional food.</p

Very long baseline interferometry with the SKA

Adding VLBI capability to the SKA arrays will greatly broaden the science of the SKA, and is feasible within the current specifications. SKA-VLBI can be initially implemented by providing phased-array outputs for SKA1-MID and SKA1-SUR and using these extremely sensitive stations with other radio telescopes, and in SKA2 by realising a distributed configuration providing baselines up to thousands of km, merging it with existing VLBI networks. The motivation for and the possible realization of SKA-VLBI is described in this paper

Lipoprotein lipase activity and mass, apolipoprotein C-II mass and polymorphisms of apolipoproteins E and A5 in subjects with prior acute hypertriglyceridaemic pancreatitis

Journal Article; Research Support, Non-U.S. Gov't;BACKGROUND Severe hypertriglyceridaemia due to chylomicronemia may trigger an acute pancreatitis. However, the basic underlying mechanism is usually not well understood. We decided to analyze some proteins involved in the catabolism of triglyceride-rich lipoproteins in patients with severe hypertriglyceridaemia. METHODS Twenty-four survivors of acute hypertriglyceridaemic pancreatitis (cases) and 31 patients with severe hypertriglyceridaemia (controls) were included. Clinical and anthropometrical data, chylomicronaemia, lipoprotein profile, postheparin lipoprotein lipase mass and activity, hepatic lipase activity, apolipoprotein C II and CIII mass, apo E and A5 polymorphisms were assessed. RESULTS Only five cases were found to have LPL mass and activity deficiency, all of them thin and having the first episode in childhood. No cases had apolipoprotein CII deficiency. No significant differences were found between the non-deficient LPL cases and the controls in terms of obesity, diabetes, alcohol consumption, drug therapy, gender distribution, evidence of fasting chylomicronaemia, lipid levels, LPL activity and mass, hepatic lipase activity, CII and CIII mass or apo E polymorphisms. However, the SNP S19W of apo A5 tended to be more prevalent in cases than controls (40% vs. 23%, NS). CONCLUSION Primary defects in LPL and C-II are rare in survivors of acute hypertriglyceridaemic pancreatitis; lipase activity measurements should be restricted to those having their first episode during childhood.Part of the studies were financed by grants from the Swedish Research Council and from the King Gustaf V and Queen Victoria Research Fund and by grants from Grupos de Investigacion y Desarrollo Tecnologico de la Junta de Andalucia (Grupo consolidado CTS- 159).Ye