944 research outputs found
Social media, protest cultures and political subjectivities of the Arab spring
This article draws on phenomenological perspectives to present a case against resisting the objectification of cultures of protest and dissent. The generative, self-organizing properties of protest cultures, especially as mobilized through social media, are frequently argued to elude both authoritarian political structures and academic discourse, leading to new political subjectivities or âimaginariesâ. Stemming from a normative commitment not to over-determine such nascent subjectivities, this view has taken on a heightened resonance in relation to the recent popular uprisings in the Middle East and North Africa. The article argues that this view is based on an invalid assumption that authentic political subjectivities and cultures naturally emerge from an absence of constraint, whether political, journalistic or academic. The valorisation of amorphousness in protest cultures and social media enables affective and political projection, but overlooks politics in its institutional, professional and procedural forms
The comprehensive model system COSMO-ART - Radiative impact of aerosol on the state of the atmosphere on the regional scale
A new fully online coupled model system developed for the evaluation of the interaction of aerosol particles with the atmosphere on the regional scale is described. The model system is based on the operational weather forecast model of the Deutscher Wetterdienst. Physical processes like transport, turbulent diffusion, and dry and wet deposition are treated together with photochemistry and aerosol dynamics using the modal approach. Based on detailed calculations we have developed parameterisations to examine the impact of aerosol particles on photolysis and on radiation. Currently the model allows feedback between natural and anthropogenic aerosol particles and the atmospheric variables that are initialized by the modification of the radiative fluxes. The model system is applied to two summer episodes, each lasting five days, with a model domain covering Western Europe and adjacent regions. The first episode is characterised by almost cloud free conditions and the second one by cloudy conditions. The simulated aerosol concentrations are compared to observations made at 700 stations distributed over Western Europe. <br><br> For each episode two model runs are performed; one where the feedback between the aerosol particles and the atmosphere is taken into account and a second one where the feedback is neglected. Comparing these two sets of model runs, the radiative feedback on temperature and other variables is evaluated. <br><br> In the cloud free case a clear correlation between the aerosol optical depth and changes in global radiation and temperature is found. In the case of cloudy conditions the pure radiative effects are superposed by changes in the liquid water content of the clouds due to changes in the thermodynamics of the atmosphere. In this case the correlation between the aerosol optical depth and its effects on temperature is low. However, on average a decrease in the 2 m temperature is still found. <br><br> For the area of Germany we found on average for both cases a reduction in the global radiation of about 6 W m<sup>2</sup>, a decrease of the 2 m temperature of 0.1 K, and a reduction in the daily temperature range of &minus;0.13 K
Assessment of correlation energies based on the random-phase approximation
The random-phase approximation to the ground state correlation energy (RPA)
in combination with exact exchange (EX) has brought Kohn-Sham (KS) density
functional theory one step closer towards a universal, "general purpose first
principles method". In an effort to systematically assess the influence of
several correlation energy contributions beyond RPA, this work presents
dissociation energies of small molecules and solids, activation energies for
hydrogen transfer and non-hydrogen transfer reactions, as well as reaction
energies for a number of common test sets. We benchmark EX+RPA and several
flavors of energy functionals going beyond it: second-order screened exchange
(SOSEX), single excitation (SE) corrections, renormalized single excitation
(rSE) corrections, as well as their combinations. Both the single excitation
correction as well as the SOSEX contribution to the correlation energy
significantly improve upon the notorious tendency of EX+RPA to underbind.
Surprisingly, activation energies obtained using EX+RPA based on a KS reference
alone are remarkably accurate. RPA+SOSEX+rSE provides an equal level of
accuracy for reaction as well as activation energies and overall gives the most
balanced performance, which makes it applicable to a wide range of systems and
chemical reactions.Comment: 14 pages, 5 figures, full articl
Junkie love : romance and addiction on the big screen
This article investigates the filmic construction of two disparate but intertwining cultural practices: those engaging in the life-affirming rituals of romantic love and those performing the potentially self-destructive rituals of hard drug consumption. Discussing a number of key feature films from the (mini) genre âjunkie loveâ, it aims to show what happens when elements of mainstream romantic drama merge with the horror conventions of the heroin addiction film. Drawing amongst others on Murray Smithâs theory of âlevels of [spectator] engagementâ and Greg Smithâs concept of the âemotion systemâ, the article concludes that junkie love films, using tropes of the romantic tragedy in the tradition of Romeo and Juliet, present a more complex and nuanced approach to drug addicts than the predominantly condemnatory media coverageâone that arguably invites the spectatorâs understanding and compassion
Image resonance in the many-body density of states at a metal surface
The electronic properties of a semi-infinite metal surface without a bulk gap are studied by a formalism that is able to account for the continuous spectrum of the system. The density of states at the surface is calculated within the GW approximation of many-body perturbation theory. We demonstrate the presence of an unoccupied surface resonance peaked at the position of the first image state. The resonance encompasses the whole Rydberg series of image states and cannot be resolved into individual peaks. Its origin is the shift in spectral weight when many-body correlation effects are taken into account
An expression signature of the angiogenic response in gastrointestinal neuroendocrine tumours: correlation with tumour phenotype and survival outcomes.
BACKGROUND: Gastroenteropancreatic neuroendocrine tumours (GEP-NETs) are heterogeneous with respect to biological behaviour and prognosis. As angiogenesis is a renowned pathogenic hallmark as well as a therapeutic target, we aimed to investigate the prognostic and clinico-pathological role of tissue markers of hypoxia and angiogenesis in GEP-NETs. METHODS: Tissue microarray (TMA) blocks were constructed with 86 tumours diagnosed from 1988 to 2010. Tissue microarray sections were immunostained for hypoxia inducible factor 1α (Hif-1α), vascular endothelial growth factor-A (VEGF-A), carbonic anhydrase IX (Ca-IX) and somatostatin receptors (SSTR) 1â5, Ki-67 and CD31. Biomarker expression was correlated with clinico-pathological variables and tested for survival prediction using KaplanâMeier and Cox regression methods. RESULTS: Eighty-six consecutive cases were included: 51% male, median age 51 (range 16â82), 68% presenting with a pancreatic primary, 95% well differentiated, 51% metastatic. Higher grading (P=0.03), advanced stage (P<0.001), high Hif-1α and low SSTR-2 expression (P=0.03) predicted for shorter overall survival (OS) on univariate analyses. Stage, SSTR-2 and Hif-1α expression were confirmed as multivariate predictors of OS. Median OS for patients with SSTR-2+/Hif-1α-tumours was not reached after median follow up of 8.8 years, whereas SSTR-2-/Hif-1α+ GEP-NETs had a median survival of only 4.2 years (P=0.006). CONCLUSION: We have identified a coherent expression signature by immunohistochemistry that can be used for patient stratification and to optimise treatment decisions in GEP-NETs independently from stage and grading. Tumours with preserved SSTR-2 and low Hif-1α expression have an indolent phenotype and may be offered less aggressive management and less stringent follow up
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