The Mutual Interpretation of Active and Passive Microwave Sensor Outputs

Mutual interpretation of active and passive microwave sensor output

Proximity-Concentration Trade-Off

Betrachtet man die großen Industrieunternehmen in Osterreich, weisen diese einen sehr unterschiedlichen Internationalisierungsgrad auf. Diese Heterogenität der großen Industrieunternehmen wirft die industriepolitisch relevante Frage auf, warum manche Unternehmen mittels Direktinvestitionen internationalisieren, während sich andere auf das Exportieren beschränken. Fragt man nach der Erklärungen für unterschiedliche Internationalisierungsgrade, hat neben vielen anderen Gründen der "Proximity - Concentration Trade-off" in der Literatur Bedeutung erlangt. Ziel dieser Studie ist es, diesen "Proximity - Concentration Trade-off" für drei ausgewählte österreichische Industrieunternehmen, welche die drei oben genannten Gruppen von Unternehmen repräsentieren, genauer zu dokumentieren: Agrolinz als ein Unternehmen, welches ausschließlich exportiert, Wienerberger als ein Unternehmen, welches ausschließlich über Tochtergesellschaften internationalisiert und die Voest als ein Unternehmen, welches beide Aktivitäten setzt. Die Auswahl der Unternehmen erfolgt anhand der Produkteigenschaften, welche durch hohe Transportkosten und hohe Skalenerträge in der Produktion gekennzeichnet sind. Es wird ermittelt, welche Rolle die Faktoren "proximity" und "concentration" als Determinanten der Entscheidung zur Direktinvestition spielen. Die Ergebnisse zeigen, dass die Skalenerträge und die Transportkosten sowie die Struktur bzw. die Größe bzw. die Kenntnis des Gastlandmarktes bestimmend für die Wahl der Alternativen "Direktinvestitionen und Exporte" als Form der Auslandsmarktbearbeitung sind. Keines der untersuchten Unternehmen wird seine Internationalisierungsstrategie in absehbarer Zukunft verändern.Foreign Direct Investment

Engaging inhabitants into energy transition in climate and energy model (CEM) regions: case studies of Freistadt, Ebreichsdorf and Baden

Austria has settled a target to reach 34% of renewable energy sources in final energy consumption by 2020. The Climate and Energy Model (CEM) regions are the major vehicles for implementation of this target. Until now little research was done on existing participatory governance measures in the Austrian CEM regions, which involve not only stakeholders but also inhabitants into decision-making processes on energy transition. The aim of this paper is to collect information about existing participatory governance measures in three CEMs, such as Freistadt, Baden and Ebreichsdorf, and to analyze these measures by using methodologies developed by Arnstein in his ladder of participation. Our results show that the majority of existing measures are at the level of providing information and awareness building. However, there are also some measures, such as energy groups, which allow all interested inhabitants for providing feedback about proposed in their CEM projects. Other measures, such as Helios or Badener Sonnerkraft, allow for financial participation of inhabitants in deployment of renewable energy projects in their region

Depth Estimation via Affinity Learned with Convolutional Spatial Propagation Network

Depth estimation from a single image is a fundamental problem in computer vision. In this paper, we propose a simple yet effective convolutional spatial propagation network (CSPN) to learn the affinity matrix for depth prediction. Specifically, we adopt an efficient linear propagation model, where the propagation is performed with a manner of recurrent convolutional operation, and the affinity among neighboring pixels is learned through a deep convolutional neural network (CNN). We apply the designed CSPN to two depth estimation tasks given a single image: (1) To refine the depth output from state-of-the-art (SOTA) existing methods; and (2) to convert sparse depth samples to a dense depth map by embedding the depth samples within the propagation procedure. The second task is inspired by the availability of LIDARs that provides sparse but accurate depth measurements. We experimented the proposed CSPN over two popular benchmarks for depth estimation, i.e. NYU v2 and KITTI, where we show that our proposed approach improves in not only quality (e.g., 30% more reduction in depth error), but also speed (e.g., 2 to 5 times faster) than prior SOTA methods.Comment: 14 pages, 8 figures, ECCV 201

Allogeneic mesenchymal stromal cells overexpressing mutant human Hypoxia-inducible factor 1-α (HIF1-α) in an ovine model of acute myocardial infarction

Background-Bone marrow mesenchymal stromal cells (BMMSCs) are cardioprotective in acute myocardial infarction (AMI) because of release of paracrine angiogenic and prosurvival factors. Hypoxia-inducible factor 1-α (HIF1-α), rapidly degraded during normoxia, is stabilized during ischemia and upregulates various cardioprotective genes. We hypothesized that BMMSCs engineered to overexpress mutant, oxygen-resistant HIF1-α would confer greater cardioprotection than nontransfected BMMSCs in sheep with AMI. Methods and Results-Allogeneic BMMSCs transfected with a minicircle vector encoding mutant HIF1-α (BMMSC-HIF) were injected in the peri-infarct of sheep (n=6) undergoing coronary occlusion. Over 2 months, infarct volume measured by cardiac magnetic resonance (CMR) imaging decreased by 71.7±1.3% (P < 0.001), and left ventricular (LV) percent ejection fraction (%EF) increased near 2-fold (P < 0.001) in the presence of markedly decreased end-systolic volume. Sheep receiving nontransfected BMMSCs (BMMSC; n=6) displayed less infarct size limitation and percent LVEF improvement, whereas in placebo-treated animals (n=6), neither parameters changed over time. HIF1-α-transfected BMMSCs (BMMSC-HIF) induced angio-/arteriogenesis and decreased apoptosis by HIF1-mediated overexpression of erythropoietin, inducible nitrous oxide synthase, vascular endothelial growth factor, and angiopoietin-1. Cell tracking using paramagnetic iron nanoparticles in 12 additional sheep revealed enhanced long-term retention of BMMSC-HIF. Conclusions-Intramyocardial delivery of BMMSC-HIF reduced infarct size and improved LV systolic performance compared to BMMSC, attributed to increased neovascularization and cardioprotective effects induced by HIF1-mediated overexpression of paracrine factors and enhanced retention of injected cells. Given the safety of the minicircle vector and the feasibility of BMMSCs for allogeneic application, this treatment may be potentially useful in the clinic.Fil: Hnatiuk, Anna. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Instituto de Medicina Traslacional, Trasplante y Bioingeniería. Fundación Favaloro. Instituto de Medicina Traslacional, Trasplante y Bioingeniería; ArgentinaFil: Ong, Sang-Ging. Stanford University School of Medicine; Estados UnidosFil: Olea, Fernanda Daniela. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Instituto de Medicina Traslacional, Trasplante y Bioingeniería. Fundación Favaloro. Instituto de Medicina Traslacional, Trasplante y Bioingeniería; ArgentinaFil: Locatelli, Paola. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Instituto de Medicina Traslacional, Trasplante y Bioingeniería. Fundación Favaloro. Instituto de Medicina Traslacional, Trasplante y Bioingeniería; ArgentinaFil: Riegler, Johannes. Stanford University School of Medicine; Estados UnidosFil: Lee, Won Hee. Stanford University School of Medicine; Estados UnidosFil: Jen, Cheng Hao. University of London; Reino UnidoFil: De Lorenzi, Andrea. Fundación Favaloro; ArgentinaFil: Giménez, Carlos Sebastián. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Instituto de Medicina Traslacional, Trasplante y Bioingeniería. Fundación Favaloro. Instituto de Medicina Traslacional, Trasplante y Bioingeniería; ArgentinaFil: Laguens, Rubén. Universidad Favaloro; ArgentinaFil: Wu, Joseph C.. Stanford University School of Medicine; Estados UnidosFil: Crottogini, Alberto José. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Instituto de Medicina Traslacional, Trasplante y Bioingeniería. Fundación Favaloro. Instituto de Medicina Traslacional, Trasplante y Bioingeniería; Argentin

Comparison of Magnetic Resonance Imaging and Serum Biomarkers for Detection of Human Pluripotent Stem Cell-Derived Teratomas.

The use of cells derived from pluripotent stem cells (PSCs) for regenerative therapies confers a considerable risk for neoplastic growth and teratoma formation. Preclinical and clinical assessment of such therapies will require suitable monitoring strategies to understand and mitigate these risks. Here we generated human-induced pluripotent stem cells (iPSCs), selected clones that continued to express reprogramming factors after differentiation into cardiomyocytes, and transplanted these cardiomyocytes into immunocompromised rat hearts post-myocardial infarction. We compared magnetic resonance imaging (MRI), cardiac ultrasound, and serum biomarkers for their ability to delineate teratoma formation and growth. MRI enabled the detection of teratomas with a volume &gt;8 mm(3). A combination of three plasma biomarkers (CEA, AFP, and HCG) was able to detect teratomas with a volume &gt;17 mm(3) and with a sensitivity of more than 87%. Based on our findings, a combination of serum biomarkers with MRI screening may offer the highest sensitivity for teratoma detection and tracking