Acetabular dysplasia and the risk of developing hip osteoarthritis at 2,5,8, and 10 years follow-up in a prospective nationwide cohort study (CHECK).

Objective: To assess the relationship between acetabular dysplasia (AD) and the risk of incident and end-stage radiographic hip osteoarthritis (RHOA) over 2,5,8 and 10 years. Design: Individuals (n = 1002) aged between 45 and 65 from the prospective Cohort Hip and Cohort Knee (CHECK) were studied. Anteroposterior pelvic radiographs were obtained at baseline and 2,5,8, and 10-years follow-up. False profile radiographs were obtained at baseline. AD was defined as a lateral center edge angle, an anterior center edge angle, or both <25° at baseline. The risk of developing RHOA was determined at each follow-up moment. Incident RHOA was defined by Kellgren & Lawrence (KL) grade ≥2 or total hip replacement (THR), end-stage RHOA by a KL grade ≥3 or THR. Associations were expressed in odds ratios (OR) using logistic regression with generalized estimating equations. Results: AD was associated with the development of incident RHOA at 2 years follow-up (OR 2.46, 95% CI 1.00–6.04), 5 years follow-up (OR 2.28, 95% CI 1.20–4.31), and 8 years follow-up (OR 1.86, 95%CI 1.22–2.83). AD was only associated with end-stage RHOA at 5 years follow-up (OR 3.75, 95% CI 1.02–13.77). No statistically significant associations were observed between AD and RHOA at 10-years follow-up. Conclusion: Baseline AD in individuals between 45 and 65 years is associated with an increased risk of developing RHOA within 2- and 5 years. However, this association seems to weaken after 8 years and disappears after 10 years

Inquérito sorológico de sífilis em adultos: Planaltina, DF, Brasil, 1977 A prevalence survey of syphilis in adults: Planaltina, DF, Brazil, 1977

Foram feitas reações sorológicas para lues - VDRL qualitativo e quantitativo - em 1502 trabalhadores de ambos os sexos, com idade compreendida entre 15 e 54 anos, moradores de Planaltina, cidade satélite do Distrito Federal, e que procuraram o hospital local, durante o ano de 1977, para exame de saúde. No setor residencial, a prevalência de soros reagentes nesse período foi de 2,3%, com taxas mais elevadas no sexo feminino, em pessoas idosas e em pessoas casadas. Na zona boêmia, de cada três prostitutas, uma apresentou sorologia positiva. Este achado reveste-se de gravidade por ser Brasília local de intenso movimento populacional.<br>In 1977, VDRL was used for serologic testing of 1502 adult male and female blue collar workers, 15 through 54 years old, residents of Planaltina, a Brasilia bedroom community. When prostitutes were excluded from the results, the prevalence rate for positive results was 2.3% being more elevated among women, married people and older ages; whereas, one in every three prostitutes showed positive. Brasilia's intense mobility rate makes this a grave public health problem