Structural design studies of a supersonic cruise arrow wing configuration

Structural member cross sections were sized with a system of integrated computer programs to satisfy strength and flutter design requirements for several variants of the arrow wing supersonic cruise vehicle. The resulting structural weights provide a measure of the structural efficiency of the planform geometry, structural layout, type of construction, and type of material including composites. The material distribution was determined for a baseline metallic structure and the results indicate that an approximate fatigue constraint has an important effect on the structural weight required for strength but, in all cases, additional material had to be added to satisfy flutter requirements with lighter mass engines with minimum fuel onboard. The use of composite materials on the baseline configuration was explored and indicated increased structural efficiency. In the strength sizing, the all-composite construction provided a lower weight design than the hybrid construction which contained composites only in the wing cover skins. Subsequent flutter analyses indicated a corresponding lower flutter speed

Developing a core outcome set for periodontal trials

Acknowledgments The authors wish to thank all patients and professionals who took part in the Delphi process and face-to-face consensus meeting. We wish to thank Jillian Sutherland, Shirley Bell, Margaret Mooney and Lorna Barnsley for helping to organise the face-to-face consensus meeting. Patient participant recruitment to this study was facilitated by SHARE–the Scottish Health Research Register. SHARE is supported by NHS Research Scotland and the Chief Scientists Office Funding: TL received research funding for the core outcome set development for the prevention and management of periodontal diseases which was provided by the Tattershall fund, Dundee Dental School. This grant provided funds for the e-Delphi software, SHARE services and the face-to-face consensus meeting travel and catering costs. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscriptPeer reviewedPublisher PD

Case Report Kingella kingae Causing Septic Arthritis of the Knee in an Immunocompetent Adult

The bacterium Kingella kingae is a species of Gram-negative coccobacillus usually found in the oropharynx. This is an emerging pathogen reported to cause bacteraemia, endocarditis, and osteoarticular infections in children and endocarditis in the immunocompromised adult. However, there are few cases of isolated joint infections reported in the immunocompetent adult. Due to specific isolation techniques required, delay in diagnosis can compromise patient outcome. We report a rare case of septic arthritis of the knee in an immunocompetent adult caused by K. kingae

The 1996 Soft State Transitions of Cygnus X-1

We report continuous monitoring of Cygnus X-1 in the 1.3 to 200 keV band using ASM/RXTE and BATSE/CGRO for about 200 days from 1996 February 21 to 1996 early September. During this period Cygnus X-1 experienced a hard-to-soft and then a soft-to-hard state transition. The low-energy X-ray (1.3-12 keV) and high-energy X-ray (20-200 keV) fluxes are strongly anti-correlated during this period. During the state transitions flux variations of about a factor of 5 and 15 were seen in the 1.3-3.0 keV and 100-200 keV bands, respectively, while the average 4.8-12 keV flux remains almost unchanged. The net effect of this pivoting is that the total 1.3-200 keV luminosity remained unchanged to within about 15%. The bolometric luminosity in the soft state may be as high as 50-70% above the hard state luminosity, after color corrections for the luminosity below 1.3 keV. The blackbody component flux and temperature increase in the soft state is probably caused by a combination of the optically thick disk mass accretion rate increase and a decrease of the inner disk radius.Comment: 18 pages, 1 PostScript figure. Accepted for ApJ

Infrared Spectroscopy of Symbiotic Stars. IV. V2116 Ophiuchi/GX 1+4, The Neutron Star Symbiotic

We have computed, based on 17 infrared radial velocities, the first set of orbital elements for the M giant in the symbiotic binary V2116 Ophiuchi. The giant's companion is a neutron star, the bright X-ray source GX 1+4. We find an orbital period of 1161 days by far the longest of any known X-ray binary. The orbit has a modest eccentricity of 0.10 with an orbital circularization time of less than 10^6 years. The large mass function of the orbit significantly restricts the mass of the M giant. Adopting a neutron-star mass of 1.35M(Sun), the maximum mass of the M giant is 1.22M(Sun), making it the less massive star. Derived abundances indicate a slightly subsolar metallicity. Carbon and nitrogen are in the expected ratio resulting from the red-giant first dredge-up phase. The lack of O-17 suggests that the M-giant has a mass less than 1.3M(Sun), consistent with our maximum mass. The red giant radius is 103R(Sun), much smaller than the estimated Roche lobe radius. Thus, the mass loss of the red giant is via a stellar wind. Although the M giant companion to the neutron star has a mass similar to the late-type star in low-mass X-ray binaries, its near-solar abundances and apparent runaway velocity are not fully consistent with the properties of this class of stars.Comment: In press to The Astrophysical Journal (10 April 2006 issue). 23 page

Participant recruitment to FiCTION, a primary dental care trial – survey of facilitators and barriers

Objective To identify reasons behind a lower than expected participant recruitment rate within the FiCTION trial, a multi-centre paediatric primary dental care randomised controlled trial (RCT). Subjects (materials) and methods An online survey, based on a previously published tool, consisting of both quantitative and qualitative responses, completed by staff in dental practices recruiting to FiCTION. Ratings from quantitative responses were aggregated to give overall scores for factors related to participant recruitment. Qualitative responses were independently grouped into themes. Results Thirty-nine anonymous responses were received. Main facilitators related to the support received from the central research team and importance of the research question. The main barriers related to low child eligibility rates and the integration of trial processes within routine workloads. Conclusions These findings have directed strategies for enhancing participant recruitment at existing practices and informed recruitment of further practices. The results help provide a profile of the features required of practices to successfully screen and recruit participants. Future trials in this setting should consider the level of interest in the research question within practices, and ensure trial processes are as streamlined as possible. Research teams should actively support practices with participant recruitment and maintain enthusiasm among the entire practice team

Battery-operated Independent Radiation Detector Data Report from Exploration Flight Test 1

Citation: Bahadori AA, Semones EJ, Gaza R, Kroupa M, Rios RR, Stoffle NN, Campbell-Ricketts T, Pinsky LS, and Turecek D 2015 Battery-operated Independent Radiation Detector Data Report from Exploration Flight Test 1 NASA/TP-2015-218575 NASA Johnson Space Center: Houston, TX http://ston.jsc.nasa.gov/collections/TRS/397.refer.htmlThis report summarizes the data acquired by the Battery-operated Independent Radiation Detector (BIRD) during Exploration Flight Test 1 (EFT-1). The BIRD, consisting of two redundant subsystems isolated electronically from the Orion Multi-Purpose Crew Vehicle (MPCV), was developed to fly on the Orion EFT-1 to acquire radiation data throughout the mission. The BIRD subsystems successfully triggered using on-board accelerometers in response to launch accelerations, acquired and archived data through landing, and completed the shut down routine when battery voltage decreased to a specified value. The data acquired are important for understanding the radiation environment within the Orion MPCV during transit through the trapped radiation belts

The convective storm initiation project

Copyright @ 2007 AMSThe Convective Storm Initiation Project (CSIP) is an international project to understand precisely where, when, and how convective clouds form and develop into showers in the mainly maritime environment of southern England. A major aim of CSIP is to compare the results of the very high resolution Met Office weather forecasting model with detailed observations of the early stages of convective clouds and to use the newly gained understanding to improve the predictions of the model. A large array of ground-based instruments plus two instrumented aircraft, from the U.K. National Centre for Atmospheric Science (NCAS) and the German Institute for Meteorology and Climate Research (IMK), Karlsruhe, were deployed in southern England, over an area centered on the meteorological radars at Chilbolton, during the summers of 2004 and 2005. In addition to a variety of ground-based remote-sensing instruments, numerous rawin-sondes were released at one- to two-hourly intervals from six closely spaced sites. The Met Office weather radar network and Meteosat satellite imagery were used to provide context for the observations made by the instruments deployed during CSIP. This article presents an overview of the CSIP field campaign and examples from CSIP of the types of convective initiation phenomena that are typical in the United Kingdom. It shows the way in which certain kinds of observational data are able to reveal these phenomena and gives an explanation of how the analyses of data from the field campaign will be used in the development of an improved very high resolution NWP model for operational use.This work is funded by the National Environment Research Council following an initial award from the HEFCE Joint Infrastructure Fund

Core outcomes in periodontal trials:study protocol for core outcome set development

Abstract Background There are a large number of clinical outcome measures used to assess the effectiveness of prevention and management strategies of periodontal diseases. This heterogeneity causes difficulties when trying to synthesise data for systematic reviews or clinical guidelines, reducing their impact. Core outcome sets are an agreed, standardised list of outcomes that should be measured and reported in all trials in specific clinical areas. We aim to develop a core outcome set for effectiveness trials investigating the prevention and management of periodontal disease in primary or secondary care. Methods To identify existing outcomes we screened the Cochrane systematic reviews and their included studies on the prevention and management of periodontal diseases. The core outcome set will be defined by consensus of key stakeholders using an online e-Delphi process and face-to-face meeting. Key stakeholders involved in the development will include: patients, dentists, hygienists/therapists, specialists, clinical researchers and policy-makers. Stakeholders will be asked to prioritise outcomes and feedback will be provided in the next round(s). Stakeholders will have an opportunity to add outcomes found in the Cochrane review screening process at the end of the first round. If consensus is not reached after the second round we will provide feedback prior to a third round. Remaining outcomes will be discussed at a face-to-face meeting and agreement will be measured via defined consensus rules of outcome inclusion. Discussion The inclusive consensus process should provide a core outcome set that is relevant to all key stakeholders. We will actively disseminate our findings to help improve clinical trials, systematic reviews and clinical guidelines with the ultimate aim of improving the prevention and management of periodontal diseases. Trial registration COMET ( http://www.comet-initiative.org/studies/details/265?result=true ). Registered on August 2012

Managing carious lesions:consensus recommendations on carious tissue removal

The International Caries Consensus Collaboration undertook a consensus process and here presents clinical recommendations for carious tissue removal and managing cavitated carious lesions, including restoration, based on texture of demineralized dentine. Dentists should manage the disease dental caries and control activity of existing cavitated lesions to preserve hard tissues and retain teeth long-term. Entering the restorative cycle should be avoided as far as possible. Controlling the disease in cavitated carious lesions should be attempted using methods which are aimed at biofilm removal or control first. Only when cavitated carious lesions either are noncleansable or can no longer be sealed are restorative interventions indicated. When a restoration is indicated, the priorities are as follows: preserving healthy and remineralizable tissue, achieving a restorative seal, maintaining pulpal health, and maximizing restoration success. Carious tissue is removed purely to create conditions for long-lasting restorations. Bacterially contaminated or demineralized tissues close to the pulp do not need to be removed. In deeper lesions in teeth with sensible (vital) pulps, preserving pulpal health should be prioritized, while in shallow or moderately deep lesions, restoration longevity becomes more important. For teeth with shallow or moderately deep cavitated lesions, carious tissue removal is performed according toselective removal to firm dentine.In deep cavitated lesions in primary or permanent teeth,selective removal to soft dentineshould be performed, although in permanent teeth,stepwise removalis an option. The evidence and, therefore, these recommendations support less invasive carious lesion management, delaying entry to, and slowing down, the restorative cycle by preserving tooth tissue and retaining teeth long-term.status: publishe