Prandtl-Blasius temperature and velocity boundary layer profiles in turbulent Rayleigh-B\'{e}nard convection

The shape of velocity and temperature profiles near the horizontal conducting plates in turbulent Rayleigh-B\'{e}nard convection are studied numerically and experimentally over the Rayleigh number range $10^8\lesssim Ra\lesssim3\times10^{11}$ and the Prandtl number range $0.7\lesssim Pr\lesssim5.4$. The results show that both the temperature and velocity profiles well agree with the classical Prandtl-Blasius laminar boundary-layer profiles, if they are re-sampled in the respective dynamical reference frames that fluctuate with the instantaneous thermal and velocity boundary-layer thicknesses.Comment: 10 pages, 6 figure

Horizontal Structures of Velocity and Temperature Boundary Layers in 2D Numerical Turbulent Rayleigh-B\'{e}nard Convection

We investigate the structures of the near-plate velocity and temperature profiles at different horizontal positions along the conducting bottom (and top) plate of a Rayleigh-B\'{e}nard convection cell, using two-dimensional (2D) numerical data obtained at the Rayleigh number Ra=10^8 and the Prandtl number Pr=4.4 of an Oberbeck-Boussinesq flow with constant material parameters. The results show that most of the time, and for both velocity and temperature, the instantaneous profiles scaled by the dynamical frame method [Q. Zhou and K.-Q. Xia, Phys. Rev. Lett. 104, 104301 (2010) agree well with the classical Prandtl-Blasius laminar boundary layer (BL) profiles. Therefore, when averaging in the dynamical reference frames, which fluctuate with the respective instantaneous kinematic and thermal BL thicknesses, the obtained mean velocity and temperature profiles are also of Prandtl-Blasius type for nearly all horizontal positions. We further show that in certain situations the traditional definitions based on the time-averaged profiles can lead to unphysical BL thicknesses, while the dynamical method also in such cases can provide a well-defined BL thickness for both the kinematic and the thermal BLs.Comment: 16 pages, 16 figure

Optimal Taylor-Couette flow: direct numerical simulations

We numerically simulate turbulent Taylor-Couette flow for independently rotating inner and outer cylinders, focusing on the analogy with turbulent Rayleigh-B\'enard flow. Reynolds numbers of $Re_i=8\cdot10^3$ and $Re_o=\pm4\cdot10^3$ of the inner and outer cylinders, respectively, are reached, corresponding to Taylor numbers Ta up to $10^8$. Effective scaling laws for the torque and other system responses are found. Recent experiments with the Twente turbulent Taylor-Couette ($T^3C$) setup and with a similar facility in Maryland at very high Reynolds numbers have revealed an optimum transport at a certain non-zero rotation rate ratio $a = -\omega_o / \omega_i$ of about $a_{opt}=0.33-0.35$. For large enough $Ta$ in the numerically accessible range we also find such an optimum transport at non-zero counter-rotation. The position of this maximum is found to shift with the driving, reaching a maximum of $a_{opt}=0.15$ for $Ta=2.5\cdot10^7$. An explanation for this shift is elucidated, consistent with the experimental result that $a_{opt}$ becomes approximately independent of the driving strength for large enough Reynolds numbers. We furthermore numerically calculate the angular velocity profiles and visualize the different flow structures for the various regimes. By writing the equations in a frame co-rotating with the outer cylinder a link is found between the local angular velocity profiles and the global transport quantities.Comment: Under consideration for publication in JFM, 31 pages, 25 figure

Boundary layer structure in turbulent thermal convection and its consequences for the required numerical resolution

Results on the Prandtl-Blasius type kinetic and thermal boundary layer thicknesses in turbulent Rayleigh-B\'enard convection in a broad range of Prandtl numbers are presented. By solving the laminar Prandtl-Blasius boundary layer equations, we calculate the ratio of the thermal and kinetic boundary layer thicknesses, which depends on the Prandtl number Pr only. It is approximated as $0.588Pr^{-1/2}$ for $Pr\ll Pr^*$ and as $0.982 Pr^{-1/3}$ for $Pr^*\ll\Pr$, with $Pr^*= 0.046$. Comparison of the Prandtl--Blasius velocity boundary layer thickness with that evaluated in the direct numerical simulations by Stevens, Verzicco, and Lohse (J. Fluid Mech. 643, 495 (2010)) gives very good agreement. Based on the Prandtl--Blasius type considerations, we derive a lower-bound estimate for the minimum number of the computational mesh nodes, required to conduct accurate numerical simulations of moderately high (boundary layer dominated) turbulent Rayleigh-B\'enard convection, in the thermal and kinetic boundary layers close to bottom and top plates. It is shown that the number of required nodes within each boundary layer depends on Nu and Pr and grows with the Rayleigh number Ra not slower than \sim\Ra^{0.15}. This estimate agrees excellently with empirical results, which were based on the convergence of the Nusselt number in numerical simulations

Flow reversals in thermally driven turbulence

We analyze the reversals of the large scale flow in Rayleigh-B\'enard convection both through particle image velocimetry flow visualization and direct numerical simulations (DNS) of the underlying Boussinesq equations in a (quasi) two-dimensional, rectangular geometry of aspect ratio 1. For medium Prandtl number there is a diagonal large scale convection roll and two smaller secondary rolls in the two remaining corners diagonally opposing each other. These corner flow rolls play a crucial role for the large scale wind reversal: They grow in kinetic energy and thus also in size thanks to plume detachments from the boundary layers up to the time that they take over the main, large scale diagonal flow, thus leading to reversal. Based on this mechanism we identify a typical time scale for the reversals. We map out the Rayleigh number vs Prandtl number phase space and find that the occurrence of reversals very sensitively depends on these parameters.Comment: 4 pages, 4 figure

Thermal boundary layer profiles in turbulent Rayleigh-B\'enard convection in a cylindrical sample

We numerically investigate the structures of the near-plate temperature profiles close to the bottom and top plates of turbulent Rayleigh-B\'{e}nard flow in a cylindrical sample at Rayleigh numbers Ra=10^8 to Ra=2\times10^{12} and Prandtl numbers Pr=6.4 and Pr=0.7 with the dynamical frame method [Q. Zhou and K.-Q. Xia, Phys. Rev. Lett. 104, 104301 (2010)] thus extending previous results for quasi-2-dimensional systems to 3D systems for the first time. The dynamical frame method shows that the measured temperature profiles in the spatially and temporally local frame are much closer to the temperature profile of a laminar, zero-pressure gradient boundary layer according to Pohlhausen than in the fixed reference frame. The deviation between the measured profiles in the dynamical reference frame and the laminar profiles increases with decreasing Pr, where the thermal BL is more exposed to the bulk fluctuations due to the thinner kinetic BL, and increasing Ra, where more plumes are passing the measurement location.Comment: 5 pages, 2 figure

Biological properties of poly-L-lysine/DNA complexes generated by cooperative binding of the polycation

We have evaluated the effect of NaCl concentration on the mode of binding of poly-L-lysine to DNA and the resulting structural and functional features of the condensed DNA particles using DNA precipitation, DNase I resistance, electron microscopy, and receptor-mediated gene transfer assays. At a high concentration of NaCl and in the presence of excess DNA, poly-L-lysine interacted with DNA cooperatively, fully condensing some of the DNA and leaving the rest of the DNA unbound. At low NaCl concentrations, poly-L-lysine molecules interacted with DNA in a noncooperative fashion, i.e. they bind randomly to the whole population of DNA molecules. Cooperative binding of poly-L-lysine to DNA occurred over a narrow range of NaCl concentrations, and the specific salt concentration depended on the length of the poly-L-lysine. The ability of condensed DNA to withstand digestion by DNase I was correlated with the structural features of the condensed DNA as determined by electron microscopy. Using our condensation procedure, cooperative binding of poly-L-lysine to DNA is a necessary prerequisite for the preparation of condensed DNA having a spherical shape and a diameter of 15-30 nm. Condensed DNA, containing galactosylated poly-L-lysine, was evaluated further for the extent and specificity of receptor-mediated gene transfer into HuH-7 human hepatoma cells via the asialoglycoprotein receptor. Efficient receptor-mediated transfection occurred only when condensed DNA complexes had a spherical shape with a diameter of 15-30 nm; asialofetuin, a natural ligand for the asialoglycoprotein receptor, inhibited this process by up to 90%. Our results support the importance of appropriate DNA condensation for the uptake and ultimate expression of DNA in hepatic cells

Logarithmic temperature profiles in turbulent Rayleigh-B\'enard convection

We report results for the temperature profiles of turbulent Rayleigh-B\'enard convection (RBC) in the interior of a cylindrical sample of aspect ratio $\Gamma \equiv D/L = 0.50$ ($D$ and $L$ are the diameter and height respectively). Results from experiment over the Rayleigh number range 4\times 10^{12} \alt Ra \alt 10^{15} for a Prandtl number \Pra \simeq 0.8 and from direct numerical simulation (DNS) at $Ra = 2 \times 10^{12}$ for \Pra = 0.7 are presented. We find that the temperature varies as $A*ln(z/L) + B$ where $z$ is the distance from the bottom or top plate. This is the case in the classical as well as in the ultimate state of RBC. From DNS we find that $A$ in the classical state decreases in the radial direction as the distance from the side wall increases and becomes small near the sample center

Hydrodynamic stability and mode coupling in Keplerian flows: local strato-rotational analysis

Aims. Qualitative analysis of key (but yet unappreciated) linear phenomena in stratified hydrodynamic Keplerian flows: (i) the occurrence of a vortex mode, as a consequence of strato-rotational balance, with its transient dynamics; (ii) the generation of spiral-density waves (also called inertia-gravity or $g\Omega$ waves) by the vortex mode through linear mode coupling in shear flows. Methods. Non-modal analysis of linearized Boussinesq equations written in the shearing sheet approximation of accretion disk flows. Results. It is shown that the combined action of rotation and stratification introduces a new degree of freedom -- vortex mode perturbation -- which is linearly coupled with the spiral-density waves. These two modes are jointly able to extract energy from the background flow and they govern the disk dynamics in the small-scale range. The transient behavior of these modes is determined by the non-normality of the Keplerian shear flow. Tightly leading vortex mode perturbations undergo substantial transient growth, then, becoming trailing, inevitably generate trailing spiral-density waves by linear mode coupling. This course of events -- transient growth plus coupling -- is particularly pronounced for perturbation harmonics with comparable azimuthal and vertical scales and it renders the energy dynamics similar to the 3D unbounded plane Couette flow case. Conclusions. Our investigation strongly suggests that the so-called bypass concept of turbulence, which has been recently developed by the hydrodynamic community for spectrally stable shear flows, can also be applied to Keplerian disks. This conjecture may be confirmed by appropriate numerical simulations that take in account the vertical stratification and consequent mode coupling in the high Reynolds number regime.Comment: A&A (accepted

Metástase, uma visão atualizada

Os autores revisam a Cascata Metastática, nome que designa a seqüência de fenômenos que levam à implantação da célula metastática e sua multiplicação no órgão alvo. Através de uma revisão atualizada da literatura pertinente, expõem as múltiplas teorias e experimentos que tentam esclarecer os complexos mecanismos bioquímicos e enzimáticos que envolvem este fascinante processo, bem como sua implicação terapêutica