Dreams and Actualities: Danforth Fellows in Mid-Career

Three Distinct Groups of Fellows Teaching: Dreams and Development Graduate Fellowships for Women, 1965-1970 Becoming Professional Colleagues Love and Work A Sense of Institutional Drift Reference

Dreams and Actualities: Danforth Fellows in Mid-Career

Three Distinct Groups of Fellows Teaching: Dreams and Development Graduate Fellowships for Women, 1965-1970 Becoming Professional Colleagues Love and Work A Sense of Institutional Drift Reference

Effects of dietary ω-3 Polyunsaturated Fatty Acids (n-3 PUFA) in light sensitivity of retinas of mice models to prevent retinal damage

Light-induced retinal degeneration (LIRD) causes photoreceptor cell death in albino mice after exposure to high intensity light for a set period of time (6-24 hours). This causes retinal photoreceptor cell death through apoptosis. From several previous studies, Dr. Mandal’s lab concluded that de novo biosynthesis of ceramide mediates photoreceptor cell death in a LIRD model. Previous studies in Dr. Mandal’s lab has shown that mouse models with higher endogenous ω-3 Polyunsaturated Fatty Acids (n-3 PUFA) generates less ceramide upon neuronal injury and prevent neurodegeneration (Mol Neurobio 2021). There are currently not many available effective therapies for retinal degeneration in humans that have inherited diseases leading to blindness. We speculate that higher endogenous n-3 PUFA will prevent retinal degeneration in mouse model of light induced retinal degeneration. This project aimed to see a significant difference between LD-Control vs LD-PUFA. Results showed that there was a significant difference between NLD-Control vs LD-Control and NLD-PUFA vs LD-PUFA. Similar levels of degeneration of retinal photoreceptors occurred in n-3 PUFA and control. n-3 PUFA has shown inconclusive results for decreasing photoreceptor cell death. Further testing should be done to confirm the significance of the effect of n-3 PUFA in a mouse-model

Professor Gene Rice Oral History Interview

https://scholarlycommons.pacific.edu/raymond-college/1086/thumbnail.jp

A Third Way beyond the Old College Teacher-Scholar Model and the University Researcher Model of Faculty Excellence

In this forum, I want us to talk about the models of academic excellence. What makes for good work? What is it that gets rewarded? I’m convinced that if we really take a careful look at American higher education there are only two models that dominate our thinking about academic excellence, and the changing character of faculty work. I also think that we need a third way, which I will discuss after considering the two models that currently dominate

WARDA's Response to the Report of the Inter-Center Rice Review

Response on behalf of the board and management of WARDA to the report of the Inter Center Rice Review. These views were presented at the discussion of the report at TAC 60, and the CGIAR meeting in May 1993. WARDA questions the methodology by which the review panel arrived at the conclusion that CGIAR rice research in Sub Saharan Africa is overfunded relative to rice research in Asia, and its recommendation that core funds be reallocated accordingly

Enhanced survival but not amplification of Francisella spp. in the presence of free-living amoebae

Transmission of Francisella tularensis, the etiologic agent of tularemia, has been associated with various water sources. Survival of many waterborne pathogens within free-living amoeba (FLA) is well documented; however, the role of amoebae in the environmental persistence of F. tularensis is unclear. In this study, axenic FLA cultures of Acanthamoeba castellanii, Acanthamoeba polyphaga, and Vermamoeba vermiformis were each inoculated with virulent strains of F. tularensis (Types A and B), the attenuated live vaccine strain, and Francisella novicida. Experimental parameters included low and high multiplicity of infection and incubation temperatures of 25 and 30 °C for 0–10 days. Francisella spp. survival was enhanced by the presence of FLA; however, bacterial growth and protozoa infectivity were not observed. In contrast, co-infections of A. polyphaga and Legionella pneumophila, used as an amoeba pathogen control, resulted in bacterial proliferation, cytopathic effects, and amoebal lysis. Collectively, even though short-term incubation with FLA was beneficial, the long-term effects on Francisella survival are unknown, especially given the expenditure of available amoebal derived nutrients and the fastidious nature of Francisella spp. These factors have clear implications for the role of FLA in Francisella environmental persistence