261 research outputs found
Absolute Calibration of a 200 MeV Proton Polarimeter for Use with the Brookhaven Linac
This work was supported by the National Science Foundation Grant NSF PHY 81-14339 and by Indiana Universit
Search for Small Trans-Neptunian Objects by the TAOS Project
The Taiwan-America Occultation Survey (TAOS) aims to determine the number of
small icy bodies in the outer reach of the Solar System by means of stellar
occultation. An array of 4 robotic small (D=0.5 m), wide-field (f/1.9)
telescopes have been installed at Lulin Observatory in Taiwan to simultaneously
monitor some thousand of stars for such rare occultation events. Because a
typical occultation event by a TNO a few km across will last for only a
fraction of a second, fast photometry is necessary. A special CCD readout
scheme has been devised to allow for stellar photometry taken a few times per
second. Effective analysis pipelines have been developed to process stellar
light curves and to correlate any possible flux changes among all telescopes. A
few billion photometric measurements have been collected since the routine
survey began in early 2005. Our preliminary result of a very low detection rate
suggests a deficit of small TNOs down to a few km size, consistent with the
extrapolation of some recent studies of larger (30--100 km) TNOs.Comment: 4 pages, 3 figures, IAU Symposium 23
Anisotropic superconductivity mediated by phonons in layered compounds with weak screening effect
Anisotropic pairing interactions mediated by phonons are examined in layer
systems. It is shown that the screening effects become weaker when the layer
spacing increases. Then the anisotropic components of the pairing interactions
increase with the screening length since the momentum dependence changes. As a
result, various types of anisotropic superconductivity occur depending on the
parameter region. For example, p-wave superconductivity occurs when the
short-range part of Coulomb repulsion is strong and the layer spacing is large.
Two kinds of inter-layer pairing may occur when the layer spacing is not too
large. Although the phonon contribution to the d-wave pairing interaction is
weaker than the p-wave interaction, it increases with the layer spacing.
Relevance of the present results to organic superconductors, high-T_c cuprates,
and Sr_2RuO_4 is discussed.Comment: 8 pages, 5 figures, (Latex, revtex.sty, epsf.sty
Strong rejuvenation in a chiral-glass superconductor
The glassy paramagnetic Meissner phase of a BiSrCaCuO
superconductor ( = 8.18) is investigated by squid magnetometry, using
``dc-memory'' experiments employed earlier to study spin glasses. The
temperature dependence of the zero-field-cooled and thermo-remanent
magnetization is recorded on re-heating after specific cooling protocols, in
which single or multiple halts are performed at constant temperatures. The
'spin' states equilibrated during the halts are retrieved on re-heating. The
observed memory and rejuvenation effects are similar to those observed in
Heisenberg-like spin glasses.Comment: REVTeX 4 style; 5 pages, 5 figure
Bell-inequality violation with "thermal" radiation
The model of a quantum-optical device for a conditional preparation of
entangled states from input mixed states is presented. It is demonstrated that
even thermal or pseudo-thermal radiation can be entangled in such a way, that
Bell-inequalities are violated
Anomalous c-axis charge dynamics in copper oxide materials
Within the t-J model, the c-axis charge dynamics of the copper oxide
materials in the underdoped and optimally doped regimes is studied by
considering the incoherent interlayer hopping. It is shown that the c-axis
charge dynamics is mainly governed by the scattering from the in-plane
fluctuation. In the optimally doped regime, the c-axis resistivity is a linear
in temperatures, and shows the metallic-like behavior for all temperatures,
while the c-axis resistivity in the underdoped regime is characterized by a
crossover from the high temperature metallic-like behavior to the low
temperature semiconducting-like behavior, which are consistent with experiments
and numerical simulations.Comment: 6 pages, Latex, Three figures are adde
Observation and Assignment of Silent and Higher Order Vibrations in the Infrared Transmission of C60 Crystals
We report the measurement of infrared transmission of large C60 single
crystals. The spectra exhibit a very rich structure with over 180 vibrational
absorptions visible in the 100 - 4000 cm-1 range. Many silent modes are
observed to have become weakly IR-active. We also observe a large number of
higher order combination modes. The temperature (77K - 300K) and pressure (0 -
25KBar) dependencies of these modes were measured and are presented. Careful
analysis of the IR spectra in conjunction with Raman scattering data showing
second order modes and neutron scattering data, allow the selection of the 46
vibrational modes C60. We are able to fit *all* of the first and second order
data seen in the present IR spectra and the previously published Raman data
(~300 lines total), using these 46 modes and their group theory allowed second
order combinations.Comment: REVTEX v3.0 in LaTeX. 12 pages. 8 Figures by request. c60lon
Large-scale pharmacogenomic study of sulfonylureas and the QT, JT and QRS intervals: CHARGE Pharmacogenomics Working Group
Sulfonylureas, a commonly used class of medication used to treat type 2 diabetes, have been associated with an increased risk of cardiovascular disease. Their effects on QT interval duration and related electrocardiographic phenotypes are potential mechanisms for this adverse effect. In 11 ethnically diverse cohorts that included 71 857 European, African-American and Hispanic/Latino ancestry individuals with repeated measures of medication use and electrocardiogram (ECG) measurements, we conducted a pharmacogenomic genome-wide association study of sulfonylurea use and three ECG phenotypes: QT, JT and QRS intervals. In ancestry-specific meta-analyses, eight novel pharmacogenomic loci met the threshold for genome-wide significance (P<5 × 10−8), and a pharmacokinetic variant in CYP2C9 (rs1057910) that has been associated with sulfonylurea-related treatment effects and other adverse drug reactions in previous studies was replicated. Additional research is needed to replicate the novel findings and to understand their biological basis
A powerful statistical framework for generalization testing in GWAS, with application to the HCHS/SOL
In genome-wide association studies (GWAS), “generalization” is the replication of genotype-phenotype association in a population with different ancestry than the population in which it was first identified. Current practices for declaring generalizations rely on testing associations while controlling the family-wise error rate (FWER) in the discovery study, then separately controlling error measures in the follow-up study. This approach does not guarantee control over the FWER or false discovery rate (FDR) of the generalization null hypotheses. It also fails to leverage the two-stage design to increase power for detecting generalized associations. We provide a formal statistical framework for quantifying the evidence of generalization that accounts for the (in)consistency between the directions of associations in the discovery and follow-up studies. We develop the directional generalization FWER (FWERg) and FDR (FDRg) controlling r-values, which are used to declare associations as generalized. This framework extends to generalization testing when applied to a published list of Single Nucleotide Polymorphism-(SNP)-trait associations. Our methods control FWERg or FDRg under various SNP selection rules based on P-values in the discovery study. We find that it is often beneficial to use a more lenient P-value threshold than the genome-wide significance threshold. In a GWAS of total cholesterol in the Hispanic Community Health Study/Study of Latinos (HCHS/SOL), when testing all SNPs with P-values < 5 × 10-8 (15 genomic regions) for generalization in a large GWAS of whites, we generalized SNPs from 15 regions. But when testing all SNPs with P-values < 6.6 × 10-5 (89 regions), we generalized SNPs from 27 regions
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