727 research outputs found
NEMO-SN1 (Western Ionian Sea, off Eastern Sicily): A Cabled Abyssal Observatory with Tsunami Early Warning Capability
The NEMO-SN1 (NEutrino Mediterranean Observatory - Submarine
Network 1) seafloor observatory is located in the central
Mediterranean, Western Ionian Sea, off Eastern Sicily Island (Southern
Italy) at 2100 m water depth, 25 km from the harbour of the city of
Catania. It is a prototype of cabled deep-sea multiparameter
observatory, and the first operating with real-time data transmission in
Europe since 2005. NEMO-SN1 is also the first-established node of
EMSO (European Multidisciplinary Seafloor Observatory,
http://emso-eu.org), one of the European large-scale research
infrastructures. EMSO will address long-term monitoring of
environmental processes related to marine ecosystems, climate change
and geo-hazards. NEMO-SN1 will perform geophysical and
environmental long-term monitoring by acquiring seismological,
geomagnetic, gravimetric, accelerometric, physico-oceanographic,
hydro-acoustic, bio-acoustic measurements to study earthquake and
tsunami generation, and to characterize ambient noise which includes
marine mammal sounds, and environmental and anthropogenic sources.
NEMO-SN1 is also equipped with a prototype tsunami detector, based
on the simultaneous measurement of the seismic and bottom pressure
signals and a new high performance tsunami detection algorithm.
NEMO-SN1 will be a permanent tsunami early warning node in
Western Ionian Sea, an area where very destructive earthquakes have
occurred in the past, some of them tsunamigenic (e.g., 1693, M=7.5;
1908, M=7.4).
Another important feature of NEMO-SN1 is the installation of a low
frequency-high sensibility hydrophone and two (scalar and vector,
respectively) magnetometers. The objective is to improve the tsunami
detection capability of SN1 through the recognition of tsunami-induced
hydro-acoustic and electro-magnetic precursors.SubmittedRhodes, Greece3A. Ambiente Marinorestricte
MODY 2: report of two cases with a new gene mutation in GCK
La diabetes MODY (Maturity Onset Diabetes of the Young) comprende un grupo heterogéneo de enfermedades monogénicas que se caracterizan por la disfunción de las células β. Se estima que ellas son responsables de 2-5% de los casos de diabetes. Se conocen más de 200 mutaciones en el gen de la glucoquinasa (GCK). En este trabajo se expone el caso de dos hermanas en las cuales se realizó el diagnóstico de MODY 2 a través del estudio genético, hallándose una mutación del gen de la GCK no descripto previamente en la bibliografía.MODY (maturity onset diabetes of the young) includes a heterogeneous group of monogenic diseases which are characterized by dysfunction of beta cells. It accounts for 2-5% of all cases of diabetes. Over 200 mutations in the glucokinase (GCK) gene are known. In this paper we discuss the cases of two sisters in which the diagnosis of MODY 2 was performed by genetic studies, and report the finding of a mutation in the GCK gene not previously described in the literature.Fil: Chiarpenello, J.. Centro de Endocrinología de Rosario; Argentina. Provincia de Santa Fe. Ministerio de Salud y Medio Ambiente - Rosario. Hospital Provincial del Centenario; ArgentinaFil: Fernández, L.. Provincia de Santa Fe. Ministerio de Salud y Medio Ambiente - Rosario. Hospital Provincial del Centenario; ArgentinaFil: Riccobene, A.. Provincia de Santa Fe. Ministerio de Salud y Medio Ambiente - Rosario. Hospital Provincial del Centenario; ArgentinaFil: Baella, A.. Provincia de Santa Fe. Ministerio de Salud y Medio Ambiente - Rosario. Hospital Provincial del Centenario; ArgentinaFil: Strallnicof, M.. Provincia de Santa Fe. Ministerio de Salud y Medio Ambiente - Rosario. Hospital Provincial del Centenario; ArgentinaFil: Castagnani, V.. Provincia de Santa Fe. Ministerio de Salud y Medio Ambiente - Rosario. Hospital Provincial del Centenario; ArgentinaFil: Herrera, M.. Provincia de Santa Fe. Ministerio de Salud y Medio Ambiente - Rosario. Hospital Provincial del Centenario; ArgentinaFil: Sermasi, V.. Provincia de Santa Fe. Ministerio de Salud y Medio Ambiente - Rosario. Hospital Provincial del Centenario; ArgentinaFil: Laurenti, N.. Provincia de Santa Fe. Ministerio de Salud y Medio Ambiente - Rosario. Hospital Provincial del Centenario; ArgentinaFil: Carretto, H.. Provincia de Santa Fe. Ministerio de Salud y Medio Ambiente - Rosario. Hospital Provincial del Centenario; Argentina. Centro de Endocrinología de Rosario; ArgentinaFil: Baquedano, María Sonia. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Córdoba. Centro de Investigaciones en Bioquímica Clínica e Inmunología; Argentin
The Particle Physics Reach of High-Energy Neutrino Astronomy
We discuss the prospects for high-energy neutrino astronomy to study particle
physics in the energy regime comparable to and beyond that obtainable at the
current and planned colliders. We describe the various signatures of
high-energy cosmic neutrinos expected in both neutrino telescopes and air
shower experiments and discuss these measurements within the context of
theoretical models with a quantum gravity or string scale near a TeV,
supersymmetry and scenarios with interactions induced by electroweak
instantons. We attempt to access the particle physics reach of these
experiments.Comment: Mini-review article for New Journal of Physics, "Focus on Neutrinos"
issue. 27 pages, 11 figure
ESONET LIDO Demonstration Mission: the East Sicily node
Off East Sicily (at 2100 m depth, 25 km off the harbour of Catania) a prototype of a cabled deep-sea observatory
(NEMO-SN1) was set up and has been operational in real-time since 2005 (the cabled deep-sea multi-parameter
station SN1, equipped with geophysical and environmental sensors and the cabled NEMO-OνDE, equipped with
4 broadband hydrophones). The Western Ionian Sea is one of the node sites for the upcoming European permanent
underwater network (EMSO). Within the activities of the EC project ESONET-NoE some demonstration missions
have been funded. The LIDO-DM (Listening to the Deep Ocean-Demonstration Mission) is one of these and is re-
lated to two sites, East Sicily and Iberian Margin (Gulf of Cadiz), the main aims being geo-hazards monitoring and
warning (seismic, tsunami, and volcanic) and bio-acoustics. The LIDO-DM East Sicily installation represents a fur-
ther major step within ESONET-NoE, resulting in a fully integrated system for multidisciplinary deep-sea science,
capable to transmit and distribute data in real time to the scientific community and to the general public. LIDO-DM
East Sicily hosts a large number of sensors aimed at monitoring and studying oceanographic and environmental
parameters (by means of CTD, ADCP, 3-C single point current meter, turbidity meter), geophysical phenomena
(low frequency hydrophones, accelerometer, gravity meter, vector and scalar magnetometers, seismometer, abso-
lute and differential pressure gauges), ocean noise monitoring and identification and tracking of biological acoustic
sources in deep sea. The latter will be performed using two tetrahedral arrays of 4 hydrophones, located at a relative
distance of about 5 km, and at about 25 km from the shore. The whole system will be connected and powered from
shore, by means of the electro-optical cable net installed at the East Sicily Site Infrastructure, and synchronised
with GPS. Sensors data sampling is performed underwater and transmitted via optical fibre link, with optimal S/N
ratio for all signals. This will also permit real-time data acquisition, analysis and distribution on-shore. Innova-
tive electronics for the off-shore data acquisition and transmission systems has been designed, built and tested.
A dedicated computing and networking infrastructure for data acquisition, storage and distribution through the
internet has been also created. The deployment and connection of the deep sea structures will be performed using
the dedicated ROV and Deep Sea Shuttle handling facilities (PEGASO, owned by INGV and INFN). LIDO-DM
constitutes the enhancement of the Western Ionian site in view of the EMSO Research Infrastructure.PublishedVienna1.8. Osservazioni di geofisica ambientaleope
The development, usability, and reliability of the Electronic Patient Visit Assessment (ePVA) for head and neck cancer
Background: Annually, over 65,000 persons are diagnosed with head and neck cancer in the United States. During treatment, up to 50% of patients become severely symptomatic with pain, fatigue, mouth sores, and inability to eat. Long term complications are lymphedema, fibrosis, dysphagia, and musculoskeletal impairment. Patients’ ability to perform daily activities and to interact socially may be impaired, resulting in poor quality of life. A pragmatic, clinically useful assessment is needed to ensure early detection and intervention for patients to report symptoms and functional limitations over time. We developed the Electronic Patient Visit Assessment (ePVA) that enables patients to report 42 symptoms related to head and neck cancer and 17 limitations of functional status. This manuscript reports (I) the development of the ePVA, (II) the content validity of the ePVA, and (III) the usability and reliability of the ePVA. Methods: Usability was evaluated using the “Think Aloud” technique to guide the iterative process to refine the ePVA based on participants’ evaluations. After signing the informed consent, 30 participants with head and neck cancer completed the ePVA using digital tablet devices while thinking aloud about ease of use. All patient conversations were recorded and professionally transcribed. Reliability of the ePVA symptom and functional limitation measures was estimated using the Kuder-Richardson test. Convergent validity of the ePVA was evaluated using the European Organization for Research and Treatment of Cancer (EORTC) QLQ-C30 global QoL/health scale. Transcribed qualitative data were analyzed using directed content analysis approach. Quantitative analyses consisted of descriptive statistics and correlation analyses. Results: Among participants, 90% strongly agreed or agreed that the ePVA system was easy to use and 80% were very satisfied. Only minor usability problems were reported due to formatting and software “bugs”. Reporting of usability problems decreased in frequency over the study period and no usability problems were reported by the last 3 participants who completed the ePVA. Based on participants’ suggestions during the iterative process, refinement of the ePVA included increased touch sensitivity of the touch screen technology and customized error messages to improve ease of use. The ePVA also recorded patient reported symptoms (mouth symptoms: 93%, fibrosis: 60%, fatigue: 60%). The ePVA demonstrated acceptable reliability (alpha =0.82–0.85) and convergent validity (ePVA total number of reported symptoms and function limitations was negatively correlated with EORTC QLQ-C30 global QOL/health scale: r=−0.55038, P<0.01). Conclusions: The ePVA was rigorously developed, accepted by patients with satisfaction, and demonstrated acceptable reliability and convergent validity. Future research will use data generated by the ePVA to determine the impact of symptom trajectories on functional status, treatment interruptions and terminations, and health resource use in head and neck cancer
NEMO: A Project for a km Underwater Detector for Astrophysical Neutrinos in the Mediterranean Sea
The status of the project is described: the activity on long term
characterization of water optical and oceanographic parameters at the Capo
Passero site candidate for the Mediterranean km neutrino telescope; the
feasibility study; the physics performances and underwater technology for the
km; the activity on NEMO Phase 1, a technological demonstrator that has
been deployed at 2000 m depth 25 km offshore Catania; the realization of an
underwater infrastructure at 3500 m depth at the candidate site (NEMO Phase 2).Comment: Proceeding of ISCRA 2006, Erice 20-27 June 200
continuous monitoring of noise levels in the gulf of catania ionian sea study of correlation with ship traffic
Abstract Acoustic noise levels were measured in the Gulf of Catania (Ionian Sea) from July 2012 to May 2013 by a low frequency
Measurement of the atmospheric muon flux with the NEMO Phase-1 detector
The NEMO Collaboration installed and operated an underwater detector
including prototypes of the critical elements of a possible underwater km3
neutrino telescope: a four-floor tower (called Mini-Tower) and a Junction Box.
The detector was developed to test some of the main systems of the km3
detector, including the data transmission, the power distribution, the timing
calibration and the acoustic positioning systems as well as to verify the
capabilities of a single tridimensional detection structure to reconstruct muon
tracks. We present results of the analysis of the data collected with the NEMO
Mini-Tower. The position of photomultiplier tubes (PMTs) is determined through
the acoustic position system. Signals detected with PMTs are used to
reconstruct the tracks of atmospheric muons. The angular distribution of
atmospheric muons was measured and results compared with Monte Carlo
simulations.Comment: Astrop. Phys., accepte
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