1,084 research outputs found
The psychology of computer displays in the modern mission control center
Work at NASA's Western Aeronautical Test Range (WATR) has demonstrated the need for increased consideration of psychological factors in the design of computer displays for the WATR mission control center. These factors include color perception, memory load, and cognitive processing abilities. A review of relevant work in the human factors psychology area is provided to demonstrate the need for this awareness. The information provided should be relevant in control room settings where computerized displays are being used
The Evolution of International Criminal Tribunals
International criminal justice is a relatively new and uniquely distinct system of criminal justice. It combines international law and criminal law from various legal systems. Historically, international law applied only to States; however, it is now applied to individuals through its merging with criminal law. The majority of States have been genuinely unwilling or unable to prosecute those most responsible for the planning and commission of international crimes. This lack of genuine willingness to prosecute perpetrators of genocide, war crimes, and crimes against humanity has resulted in the recent creation of multiple international criminal tribunals. The emergence of international and quasi-international criminal tribunals should not reflect the assumption that the idea of such courts is new. On the contrary, the idea and discussions for creating international criminal tribunals have been with us for well over a century. This article traces the evolution of international criminal tribunals starting from 1864. Each major debate to establish an international criminal tribunal is closely analyzed. The article concludes with analysis of the International Criminal Court
Anthropology in Florida
Any attempt to investigate the origin and customs of the aborigines of Florida through reliance on written materials is almost immediately frustrated by the paucity of such material and the scantiness of data available. Even an attempt to summarize the work done by field investigators leads to the baffling task of trying to reconcile conflicting theories, a condition that arises from the fact that the conclusions reached as to the origin, antiquity, and life of the early peoples of Florida are so indefinite. Yet there are few regions in the United States more abundantly supplied with mounds that call for further investigation
The United States And International Criminal Tribunals: An Historical Analysis
The relationship between the United States and international criminal tribunals has lasted for almost 100 years at least
Racial Strains in Florida
This paper was prepared for and read before the annual meeting of the Florida Historical Society, held at Rollins College, February 29 last
A refined sub-grid model for black hole accretion and AGN feedback in large cosmological simulations
In large scale cosmological hydrodynamic simulations simplified sub-grid
models for gas accretion onto black holes and AGN feedback are commonly used.
Such models typically depend on various free parameters, which are not well
constrained. We present a new advanced model containing a more detailed
description of AGN feedback, where those parameters reflect the results of
recent observations. The model takes the dependency of these parameters on the
black hole properties into account and describes a continuous transition
between the feedback processes acting in the so-called radio-mode and
quasar-mode. In addition, we implement a more detailed description of the
accretion of gas onto black holes by distinguishing between hot and cold gas
accretion. Our new implementations prevent black holes from gaining too much
mass, particularly at low redshifts so that our simulations are now very
successful in reproducing the observed present-day black hole mass function.
Our new model also suppresses star formation in massive galaxies slightly more
efficiently than many state-of-the-art models. Therefore, the simulations that
include our new implementations produce a more realistic population of
quiescent and star-forming galaxies compared to recent observations, even if
some discrepancies remain. In addition, the baryon conversion efficiencies in
our simulation are - except for the high mass end - consistent with
observations presented in literature over the mass range resolved by our
simulations. Finally, we discuss the significant impact of the feedback model
on the low-luminous end of the AGN luminosity function.Comment: 25 pages, 19 figures. MNRAS accepted. Magneticum website:
http://www.magneticum.or
Origin and properties of dual and offset active galactic nuclei in a cosmological simulation at z=2
In the last few years, it became possible to observationally resolve galaxies
with two distinct nuclei in their centre. For separations smaller than 10kpc,
dual and offset active galactic nuclei (AGN) are distinguished: in dual AGN,
both nuclei are active, whereas in offset AGN only one nucleus is active. To
study the origin of such AGN pairs, we employ a cosmological, hydrodynamic
simulation with a large volume of (182Mpc)^3 from the set of Magneticum
Pathfinder Simulations. The simulation self-consistently produces 35 resolved
black hole (BH) pairs at redshift z=2, with a comoving distance smaller than
10kpc. 14 of them are offset AGN and nine are dual AGN, resulting in a fraction
of (1.2 \pm 0.3)% AGN pairs with respect to the total number of AGN. In this
paper, we discuss fundamental differences between the BH and galaxy properties
of dual AGN, offset AGN and inactive BH pairs and investigate their different
triggering mechanisms. We find that in dual AGN the BHs have similar masses and
the corresponding BH from the less massive progenitor galaxy always accretes
with a higher Eddington ratio. In contrast, in offset AGN the active BH is
typically more massive than its non-active counterpart. Furthermore, dual AGN
in general accrete more gas from the intergalactic medium than offset AGN and
non-active BH pairs. This highlights that merger events, particularly minor
mergers, do not necessarily lead to strong gas inflows and thus, do not always
drive strong nuclear activity.Comment: 17 pages, 18 figures, accepted for publication in MNRAS, website:
http://www.magneticum.or
The Proprotein Convertase Encoded by amontillado (amon) Is Required in Drosophila Corpora Cardiaca Endocrine Cells Producing the Glucose Regulatory Hormone AKH
Peptide hormones are potent signaling molecules that coordinate animal physiology, behavior, and development. A key step in activation of these peptide signals is their proteolytic processing from propeptide precursors by a family of proteases, the subtilisin-like proprotein convertases (PCs). Here, we report the functional dissection of amontillado (amon), which encodes the Drosophila homolog of the mammalian PC2 protein, using cell-type specific inactivation and rescue experiments, and we show that amon is required in the islet-like adipokinetic hormone (AKH)–producing cells that regulate sugar homeostasis. In Drosophila, AKH acts analogously to vertebrate glucagon to increase circulating sugar levels from energy stores, while insulin-like peptides (DILPs) act to decrease sugar levels. amon mutant larvae have significantly reduced hemolymph sugar levels, and thus phenocopy larvae where the AKH–producing cells in the corpora cardiaca have been ablated. Reduction of amon expression in these cells via cell-specific RNA inactivation also results in larvae with reduced sugar levels while expression of amon in AKH cells in an amon mutant background rescues hypoglycemia. Hypoglycemia in larvae resulting from amon RNA inactivation in the AKH cells can be rescued by global expression of the akh gene. Finally, mass spectrometric profiling shows that the production of mature AKH is inhibited in amon mutants. Our data indicate that amon function in the AKH cells is necessary to maintain normal sugar homeostasis, that amon functions upstream of akh, and that loss of mature AKH is correlated with loss of amon activity. These observations indicate that the AKH propeptide is a proteolytic target of the amon proprotein convertase and provide evidence for a conserved role of PC2 in processing metabolic peptide hormones
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