Metodología para diagnosticar la gestión de la política laboral en el municipio Viñales

Aim: To design a methodology that contributes to labor managementcharacterization in the touristic municipality of Viñales, province of Pinar delRio, Cuba.Methods and techniques: The systemic method facilitated the conception ofthe methodology, depending on the elements of the executing cycle, whichmake up suitable input to identify the complex inter-sector grid thatcharacterizes performance and decision-making in the implementation of laborpolicies. Interviews and surveys were used to determine the measurementmethod. Awareness creation workshops were delivered. The analysis andsynthesis method was conducted for decomposition and relations of theoreticalaspects. Minitab 19 was used for statistical analysis.Results: The methodology was proposed to identify distinctive findings, andthe materialization of statements directed to the treatment of interests andrequirements in the working context of Viñales.Conclusions: This approach to labor policy management permitted theconfirmation of its traditional character. It shows little response to theparticularities of the municipality, and reveals the absence of integration,misuse of potentialities, and the wiil to collaborate of the private sector, whichare relevant elements to increase the development of new ways of performing,that can be adapted to the particular surrounding. Objetivo: Una metodología, cuya aplicación contribuya a caracterizar la gestión de la política laboral en el turístico municipio de Viñales, provincia Pinar del Río, Cuba. Métodos y técnicas: El método sistémico propició la concepción de la metodología a partir de los elementos del ciclo directivo que constituyen un insumo competente para identificar el complejo entramado interactoral que caracteriza el desempeño y la toma de decisiones en la implementación de la política laboral. En la delimitación del método de medición se usaron las entrevistas y encuestas como fuentes de información. Se desarrollaron talleres de sensibilización. Los procedimientos de análisis y síntesis se aplicaron en la descomposición y relación de los aspectos teóricos. Se empleó el software estadístico Minitab versión 19. Los procedimientos de análisis y síntesis se aplicaron en la descomposición y relación de los aspectos teóricos. Resultados: La propuesta de una metodología para el levantamiento de los hallazgos representativos y la concreción de planteamientos dirigidos al tratamiento de intereses y demandas en el contexto laboral del municipio de Viñales.  Conclusiones: El acercamiento a la gestión de la política laboral permitió comprobar su carácter tradicional; denota la poca respuesta a las particularidades del municipio y revela la falta de integración y desaprovechamiento de las potencialidades y disposición de colaboración del sector privado, elementos relevantes para impulsar el desarrollo de nuevas formas de hacer contextualizadas al medio.&nbsp

Anderson localization and Brewster anomalies in photonic disordered quasiperiodic lattices

ABSTRACT: A comprehensive study of the properties of light propagation through one-dimensional photonic disordered quasiperiodic superlattices, composed of alternating layers with random thicknesses of air and a dispersive metamaterial, is theoretically performed. The superlattices consist of the successive stacking of N quasiperiodic Fibonacci or Thue-Morse heterostructures. The width of the slabs in the photonic superlattice may randomly fluctuate around its mean value, which introduces a structural disorder into the system. It is assumed that the left-handed layers have a Drude-type dispersive response for both the dielectric permittivity and magnetic permeability, and Maxwell’s equations are solved for oblique incidence by using the transfer-matrix formalism. The influence of both quasiperiodicity and structural disorder on the localization length and Brewster anomalies are thoroughly discussed

Suppression of Anderson localization of light in one-dimensional disordered photonic superlattices

ABSTRACT: The localization properties of electromagnetic modes in one-dimensional disordered photonic superlattices are theoretically studied. The multilayered system is considered to be composed of alternating stacks of two different random-thickness slabs, characterized by nondispersive and/or frequency-dependent electric permittivities and magnetic permeabilities. Results for the localization length are evaluated by using an analytical model for weakly disordered systems as well as its general definition through the transmissivity properties of the heterostructure. Good agreement between both results is observed only for small amplitudes of disorder. The critical frequencies at which the localization length diverges are correctly predicted in the whole frequency spectrum by the analytical model and confirmed via the corresponding numerical calculations. The λ2 dependence of the localization length, previously observed in disordered heterostructures made of material of positive refractive indexes, are confirmed in the present work. In addition, new λ4 and λ−4 dependencies of the localization length in positive-negative disordered photonic superlattices are obtained, under certain specific conditions, in the long and short wavelength limits, respectively. The asymptotic behavior of the localization length in these limits is essentially determined by the particular frequency dispersion that characterizes the metamaterial used in the left-handed layers. When the effects of absorption are considered, then a divergence of the localization length is still observed, under some conditions, in the short wavelength limit

Metodología para diagnosticar la gestión de la política laboral en el municipio Viñales

Aim: To design a methodology that contributes to labor management characterization in the touristic municipality of Viñales, province of Pinar del Rio, Cuba. Methods and techniques: The systemic method facilitated the conception of the methodology, depending on the elements of the executing cycle, which make up suitable input to identify the complex inter-sector grid that characterizes performance and decision-making in the implementation of labor policies. Interviews and surveys were used to determine the measurement method. Awareness creation workshops were delivered. The analysis and synthesis method was conducted for decomposition and relations of theoretical aspects. Minitab 19 was used for statistical analysis. Results: The methodology was proposed to identify distinctive findings, and the materialization of statements directed to the treatment of interests and requirements in the working context of Viñales. Conclusions: This approach to labor policy management permitted the confirmation of its traditional character. It shows little response to the particularities  of  the  municipality,  and  reveals  the  absence  of  integration, misuse of potentialities, and the wiil to collaborate of the private sector, which are relevant elements to increase the development of new ways of performing, that can be adapted to the particular surrounding

Human genetic selection on the MTHFR 677C>T polymorphism

<p>Abstract</p> <p>Background</p> <p>The prevalence of genotypes of the 677C>T polymorphism for the MTHFR gene varies among humans. In previous studies, we found changes in the genotypic frequencies of this polymorphism in populations of different ages, suggesting that this could be caused by an increase in the intake of folate and multivitamins by women during the periconceptional period. The aim was to analyze changes in the allelic frequencies of this polymorphism in a Spanish population, including samples from spontaneous abortions (SA).</p> <p>Methods</p> <p>A total of 1305 subjects born in the 20th century were genotyped for the 677C>T polymorphism using allele specific real-time PCR with Taqman^®probes. A section of our population (n = 276) born in 1980–1989 was compared with fetal samples (n = 344) from SA of unknown etiology from the same period.</p> <p>Results</p> <p>An increase in the frequency of the T allele (0.38 vs 0.47; p < 0.001) and of the TT genotype (0.14 vs 0.24; p < 0.001) in subjects born in the last quarter of the century was observed. In the 1980–1989 period, the results show that the frequency of the wild type genotype (CC) is about tenfold lower in the SA samples than in the controls (0.03 vs 0.33; p < 0.001) and that the frequency of the TT genotype increases in the controls (0.19 to 0.27) and in the SA samples (0.20 to 0.33 (p < 0.01)); r = 0.98.</p> <p>Conclusion</p> <p>Selection in favor of the T allele has been detected. This selection could be due to the increased fetal viability in early stages of embryonic development, as is deduced by the increase of mutants in both living and SA populations.</p

Lo tangible e intangible del diseño

1 archivo PDF (366 páginas)"El Departamento de Evaluación del Diseño, en el Tiempo de la División de Ciencias y Artes para el Diseño de la Universidad Autónoma Metropolitana, Azcapotzalco, publica este libro colectivo, donde se aborda la discusión y el análisis sobre "Lo tangible e intangible del diseño". Este libro tiene como finalidad el profundizar en distintas posiciones teóricas, metodológicas y empíricas, donde un grupo interdisciplinario de profesores investigadores del Departamento de Evaluación, desde la arquitectura, los estudios urbanos, la educación, la historia, la semiótica, el diseño de la comunicación gráfica y el industrial; buscan convergencias y discuten divergencias que puedan generar servir como referentes intelectuales y teóricos, en el diseño. Este libro es resultado del Cuarto Coloquio Departamental: Lo tangible e Intangible del Diseño. Evaluación de Objetos, Espacios, Mensajes, realizado durante el mes de septiembre del año 2004, el cual se constituyó como un espacio para el intercambio de experiencias académicas y profesionales, desde una perspectiva interdisciplinaria, centrada en la reflexión y la discusión sobre la manera de cómo se puede analizar, definir y evaluar, lo tangible y lo intangible en el diseño"

Trail Marking by Caterpillars of the Silverspot Butterfly Dione Juno Huascuma

A pheromone is implicated in the trail marking behavior of caterpillars of the nymphalid silverspot butterfly, Dione juno huascuma (Reakirt) (Lepidoptera: Heliconiinae) that feed gregariously on Passiflora (Malpighiales: Passifloraceae) vines in Mexico. Although they mark pathways leading from one feeding site to another with silk, this study shows that the silk was neither adequate nor necessary to elicit trail following behavior. Caterpillars marked trails with a long-lived pheromone that was deposited when they brushed the ventral surfaces of the tips of their abdomens along branch pathways. The caterpillars distinguished between pathways deposited by different numbers of siblings and between trails of different ages. Caterpillars also preferentially followed the trails of conspecifics over those of another nymphalid, Nymphalis antiopa L., the mourning cloak butterfly

DNA Methylation-Independent Reversion of Gemcitabine Resistance by Hydralazine in Cervical Cancer Cells

BACKGROUND: Down regulation of genes coding for nucleoside transporters and drug metabolism responsible for uptake and metabolic activation of the nucleoside gemcitabine is related with acquired tumor resistance against this agent. Hydralazine has been shown to reverse doxorubicin resistance in a model of breast cancer. Here we wanted to investigate whether epigenetic mechanisms are responsible for acquiring resistance to gemcitabine and if hydralazine could restore gemcitabine sensitivity in cervical cancer cells. METHODOLOGY/PRINCIPAL FINDINGS: The cervical cancer cell line CaLo cell line was cultured in the presence of increasing concentrations of gemcitabine. Down-regulation of hENT1 & dCK genes was observed in the resistant cells (CaLoGR) which was not associated with promoter methylation. Treatment with hydralazine reversed gemcitabine resistance and led to hENT1 and dCK gene reactivation in a DNA promoter methylation-independent manner. No changes in HDAC total activity nor in H3 and H4 acetylation at these promoters were observed. ChIP analysis showed H3K9m2 at hENT1 and dCK gene promoters which correlated with hyper-expression of G9A histone methyltransferase at RNA and protein level in the resistant cells. Hydralazine inhibited G9A methyltransferase activity in vitro and depletion of the G9A gene by iRNA restored gemcitabine sensitivity. CONCLUSIONS/SIGNIFICANCE: Our results demonstrate that acquired gemcitabine resistance is associated with DNA promoter methylation-independent hENT1 and dCK gene down-regulation and hyper-expression of G9A methyltransferase. Hydralazine reverts gemcitabine resistance in cervical cancer cells via inhibition of G9A histone methyltransferase