8,531 research outputs found
Signal transmission through the dark-adapted retina of the toad (Bufo marinus). Gain, convergence, and signal/noise.
Responses to light were recorded from rods, horizontal cells, and ganglion cells in dark-adapted toad eyecups. Sensitivity was defined as response amplitude per isomerization per rod for dim flashes covering the excitatory receptive field centers. Both sensitivity and spatial summation were found to increase by one order of magnitude between rods and horizontal cells, and by two orders of magnitude between rods and ganglion cells. Recordings from two hyperpolarizing bipolar cells showed a 20 times response increase between rods and bipolars. At absolute threshold for ganglion cells (Copenhagen, D.R., K. Donner, and T. Reuter. 1987. J. Physiol. 393:667-680) the dim flashes produce 10-50-microV responses in the rods. The cumulative gain exhibited at each subsequent synaptic transfer from the rods to the ganglion cells serves to boost these small amplitude signals to the level required for initiation of action potentials in the ganglion cells. The convergence of rod signals through increasing spatial summation serves to decrease the variation of responses to dim flashes, thereby increasing the signal-to-noise ratio. Thus, at absolute threshold for ganglion cells, the convergence typically increases the maximal signal-to-noise ratio from 0.6 in rods to 4.6 in ganglion cells
kmos: A lattice kinetic Monte Carlo framework
Kinetic Monte Carlo (kMC) simulations have emerged as a key tool for
microkinetic modeling in heterogeneous catalysis and other materials
applications. Systems, where site-specificity of all elementary reactions
allows a mapping onto a lattice of discrete active sites, can be addressed
within the particularly efficient lattice kMC approach. To this end we describe
the versatile kmos software package, which offers a most user-friendly
implementation, execution, and evaluation of lattice kMC models of arbitrary
complexity in one- to three-dimensional lattice systems, involving multiple
active sites in periodic or aperiodic arrangements, as well as site-resolved
pairwise and higher-order lateral interactions. Conceptually, kmos achieves a
maximum runtime performance which is essentially independent of lattice size by
generating code for the efficiency-determining local update of available events
that is optimized for a defined kMC model. For this model definition and the
control of all runtime and evaluation aspects kmos offers a high-level
application programming interface. Usage proceeds interactively, via scripts,
or a graphical user interface, which visualizes the model geometry, the lattice
occupations and rates of selected elementary reactions, while allowing
on-the-fly changes of simulation parameters. We demonstrate the performance and
scaling of kmos with the application to kMC models for surface catalytic
processes, where for given operation conditions (temperature and partial
pressures of all reactants) central simulation outcomes are catalytic activity
and selectivities, surface composition, and mechanistic insight into the
occurrence of individual elementary processes in the reaction network.Comment: 21 pages, 12 figure
On the Possibility of Quantum Gravity Effects at Astrophysical Scales
The nonperturbative renormalization group flow of Quantum Einstein Gravity
(QEG) is reviewed. It is argued that at large distances there could be strong
renormalization effects, including a scale dependence of Newton's constant,
which mimic the presence of dark matter at galactic and cosmological scales.Comment: LaTeX, 18 pages, 4 figures. Invited contribution to the Int. J. Mod.
Phys. D special issue on dark matter and dark energ
Renormalization Group Flow of Quantum Gravity in the Einstein-Hilbert Truncation
The exact renormalization group equation for pure quantum gravity is used to
derive the non-perturbative \Fbeta-functions for the dimensionless Newton
constant and cosmological constant on the theory space spanned by the
Einstein-Hilbert truncation. The resulting coupled differential equations are
evaluated for a sharp cutoff function. The features of these flow equations are
compared to those found when using a smooth cutoff. The system of equations
with sharp cutoff is then solved numerically, deriving the complete
renormalization group flow of the Einstein-Hilbert truncation in . The
resulting renormalization group trajectories are classified and their physical
relevance is discussed. The non-trivial fixed point which, if present in the
exact theory, might render Quantum Einstein Gravity nonperturbatively
renormalizable is investigated for various spacetime dimensionalities.Comment: 58 pages, latex, 24 figure
Blue-fluorescence of NADPH as an indicator of marine primary production
Nicotinamide Adenine Dinucleotide Phosphate (NADPH) is the primary product of photosynthesisand can therefore serve as an indicator of biomass and photosynthetic activity. Pure NADPH whichis the reduced form of NADP shows an absorption maximum at 340 nm and a maximum of emissionat 460 nm. NADPH concentrations in terrestrial vegetation have already been studied since1957 in great detail with optical methods. However, its potential as a biomass parameter of oceanicphytoplankton which can be assessed in situ and remotely with fluorescence spectroscopy has notyet been investigated.In this paper, we report on laboratory investigations of the blue-fluorescence spectrum in algalsuspensions of Chlorella and Thalassiosira when excited with UV-A light. It is shown that cell densitiesof about 106 per litre as they are typically found under natural conditions are too low for precisedetection of NADPH fluorescence, while concentrated samples with 108-1010 cells per litre exhibitsignificant blue-fluorescence which can be related to NADPH. Inhibition of photosynthetic activityby addition of DCMU decreases the strength of blue-fluorescence remarkably. Since NADPHis an end product of photosynthesis, changes of PAR illumination levels should directly affect itsconcentration and hence the intensity of blue-fluorescence. However, no effect of illumination onblue-fluorescence could be observed in our study. Possible reasons of these observations are discussed,and perspectives for practical applications of the method used are proposed
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Evolutionary dynamics of the Yersinia enterocolitica complex
The genus Yersinia consists of a heterogeneous collection of organisms, comprising the highly pathogenic species Yersinia pestis, enteropathogens Yersinia pseudotuberculosis and Yersinia enterocolitica as well as environmental species. The evolutionary history of Y. pestis has been well documented, but information on the evolutionary relationship between the other Yersiniae is less characterized. Y. enterocolitica is a diverse species classed into six different biotypes (BT), but only a single genome sequence for high-pathogenic BT 1B was available at the start of the project
Nonperturbative renomalization group for Einstein gravity with matter
we investigate the exact renormalization group (RG) in Einstein gravity
coupled to N-component scalar field, working in the effective average action
formalism and background field method. The truncated evolution equation is
obtained for the Newtonian and cosmological constants. We have shown that
screening or antiscreening behaviour of the gravitational coupling depends
cricially on the choice of scalar-gravitational and the number of scalar
fields.Comment: 7 pages, LaTeX, a few typos correcte
Running Gauge Coupling in Asymptotically Safe Quantum Gravity
We investigate the non-perturbative renormalization group behavior of the
gauge coupling constant using a truncated form of the functional flow equation
for the effective average action of the Yang-Mills-gravity system. We find a
non-zero quantum gravity correction to the standard Yang-Mills beta function
which has the same sign as the gauge boson contribution. Our results fit into
the picture according to which Quantum Einstein Gravity (QEG) is asymptotically
safe, with a vanishing gauge coupling constant at the non-trivial fixed point.Comment: 27 page
A resonance without resonance: scrutinizing the diphoton excess at 750 GeV
Motivated by the recent diphoton excesses reported by both ATLAS and CMS
collaborations, we suggest that a new heavy spinless particle is produced in
gluon fusion at the LHC and decays to a couple of lighter pseudoscalars which
then decay to photons. The new resonances could arise from a new strongly
interacting sector and couple to Standard Model gauge bosons only via the
corresponding Wess-Zumino-Witten anomaly. We present a detailed recast of the
newest 13 TeV data from ATLAS and CMS together with the 8 TeV data to scan the
consistency of the parameter space for those resonances.Comment: 8 pages, 4 figures, extended discussion of underlying models, new
plots with varying mass of the heavy scalar, to appear in PL
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