Extreme wind speed distribution in a mixed wind climate

The meteorological services of mid-latitude countries record wind speeds averaged over 10 min or 1 h periods and peak wind speeds for the same averaging period or a full day. Design wind speeds based on the statistical analysis of this data in a mixed wind climate may prove to be imprecise and unsafe due to the occurrence of intense, small and rapid extreme wind events such as thunderstorm outflows. Considering the 6 year continuous high-frequency records registered in two Port areas of the Upper Tyrrhenian Sea, a preliminary but representative analysis of the extreme wind speed distribution has been carried out in a mixed wind climate area frequently struck by thunderstorms. Results show that wind speeds with a high return period are always related to thunderstorm outflows. The mixed extreme distribution asymptotically overlaps with that for thunderstorms for high return periods and always provides the highest wind speeds. Gathering the ensemble of all extreme values into a single set leads to underestimating of the extreme wind speed. The Italian code provides conservative estimates of the extreme wind speed that protect designers from thunderstorms as well. However, refined analyses of the local wind climate that ignore thunderstorm events may lead to severe underestimations of the design wind velocity

A New Paradigm to Address Threats for Virtualized Services

With the uptaking of virtualization technologies and the growing usage of public cloud infrastructures, an ever larger number of applications run outside of the traditional enterprise’s perimeter, and require new security paradigms that fit the typical agility and elasticity of cloud models in service creation and management. Though some recent proposals have integrated security appliances in the logical application topology, we argue that this approach is sub-optimal. Indeed, we believe that embedding security agents in virtualization containers and delegating the control logic to the software orchestrator provides a much more effective, flexible, and scalable solution to the problem. In this paper, we motivate our mindset and outline a novel framework for assessing cyber-threats of virtualized applications and services. We also review existing technologies that build the foundation of our proposal, which we are going to develop in the context of a joint research project

Near Infra-Red Spectroscopy: a low cost device

Abstract In vivo near infra-red spectroscopy ( NIRS) is based on interrogation of tissue with light, a non invasive measurement. Penetration with near infra-red wavelengths in tissues is greater than with visible light, and specific absorption by compounds relevant for diagnosis and monitoring enable safe and convenient in vivo measurement.. NIRS can be used for the early diagnosis of cerebral pathologies of vascular origin, cortical blood flow monitoring and the analysis of cortical activity. Recent advances in microelectronics make it possible to build small, portable, low-cost NIRS instruments capable of measuring chemical compounds relevant for diagnosis and monitoring. We have developed a low cost NIR module to be used for spectroscopy and imaging. This device is based on emitter -detector modules using laser diodes and PIN photodiodes, overcoming disadvantages of vacuum photomultipliers, and obviates the need for optical fibre connection. We have used intensity modulation with spatially resolved measurements. For measurements of (O2Hb) an (HHb) two wavelengths are sufficient. For each of them we measure demodulation and phase shift and hence the absorption coefficient and the reduced scattering coefficient, from which chromophore concentrations can be determined. Detector signal analysis and sequentially controlled switching is achieved using a Pentium III computer. The module has a cost below a few hundreds US dollars and it is quite small, and can be used for cortical oxygenation maps

Psychological treatments and psychotherapies in the neurorehabilitation of pain. Evidences and recommendations from the italian consensus conference on pain in neurorehabilitation

BACKGROUND: It is increasingly recognized that treating pain is crucial for effective care within neurological rehabilitation in the setting of the neurological rehabilitation. The Italian Consensus Conference on Pain in Neurorehabilitation was constituted with the purpose identifying best practices for us in this context. Along with drug therapies and physical interventions, psychological treatments have been proven to be some of the most valuable tools that can be used within a multidisciplinary approach for fostering a reduction in pain intensity. However, there is a need to elucidate what forms of psychotherapy could be effectively matched with the specific pathologies that are typically addressed by neurorehabilitation teams. OBJECTIVES: To extensively assess the available evidence which supports the use of psychological therapies for pain reduction in neurological diseases. METHODS: A systematic review of the studies evaluating the effect of psychotherapies on pain intensity in neurological disorders was performed through an electronic search using PUBMED, EMBASE, and the Cochrane Database of Systematic Reviews. Based on the level of evidence of the included studies, recommendations were outlined separately for the different conditions. RESULTS: The literature search yielded 2352 results and the final database included 400 articles. The overall strength of the recommendations was medium/low. The different forms of psychological interventions, including Cognitive-Behavioral Therapy, cognitive or behavioral techniques, Mindfulness, hypnosis, Acceptance and Commitment Therapy (ACT), Brief Interpersonal Therapy, virtual reality interventions, various forms of biofeedback and mirror therapy were found to be effective for pain reduction in pathologies such as musculoskeletal pain, fibromyalgia, Complex Regional Pain Syndrome, Central Post-Stroke pain, Phantom Limb Pain, pain secondary to Spinal Cord Injury, multiple sclerosis and other debilitating syndromes, diabetic neuropathy, Medically Unexplained Symptoms, migraine and headache. CONCLUSIONS: Psychological interventions and psychotherapies are safe and effective treatments that can be used within an integrated approach for patients undergoing neurological rehabilitation for pain. The different interventions can be specifically selected depending on the disease being treated. A table of evidence and recommendations from the Italian Consensus Conference on Pain in Neurorehabilitation is also provided in the final part of the pape

What is the role of the placebo effect for pain relief in neurorehabilitation? Clinical implications from the Italian consensus conference on pain in neurorehabilitation

Background: It is increasingly acknowledged that the outcomes of medical treatments are influenced by the context of the clinical encounter through the mechanisms of the placebo effect. The phenomenon of placebo analgesia might be exploited to maximize the efficacy of neurorehabilitation treatments. Since its intensity varies across neurological disorders, the Italian Consensus Conference on Pain in Neurorehabilitation (ICCP) summarized the studies on this field to provide guidance on its use. Methods: A review of the existing reviews and meta-analyses was performed to assess the magnitude of the placebo effect in disorders that may undergo neurorehabilitation treatment. The search was performed on Pubmed using placebo, pain, and the names of neurological disorders as keywords. Methodological quality was assessed using a pre-existing checklist. Data about the magnitude of the placebo effect were extracted from the included reviews and were commented in a narrative form. Results: 11 articles were included in this review. Placebo treatments showed weak effects in central neuropathic pain (pain reduction from 0.44 to 0.66 on a 0-10 scale) and moderate effects in postherpetic neuralgia (1.16), in diabetic peripheral neuropathy (1.45), and in pain associated to HIV (1.82). Moderate effects were also found on pain due to fibromyalgia and migraine; only weak short-term effects were found in complex regional pain syndrome. Confounding variables might have influenced these results. Clinical implications: These estimates should be interpreted with caution, but underscore that the placebo effect can be exploited in neurorehabilitation programs. It is not necessary to conceal its use from the patient. Knowledge of placebo mechanisms can be used to shape the doctor-patient relationship, to reduce the use of analgesic drugs and to train the patient to become an active agent of the therapy