22 research outputs found
US Cosmic Visions: New Ideas in Dark Matter 2017: Community Report
Get PDFThis white paper summarizes the workshop "U.S. Cosmic Visions: New Ideas in Dark Matter" held at University of Maryland on March 23-25, 2017
Proton MR Spectroscopy–Detectable Major Neurotransmitters of the Brain: Biology and Possible Clinical Applications
No full textSuper-paramagnetic iron oxide nanoparticles for use in extrapulmonary tuberculosis diagnosis
Get PDFAbstractThe limited sensitivity of serological tests for mycobacterial antigens has encouraged the development of a nanoparticle probe specific for the extrapulmonary form of Mycobacterium tuberculosis (Mtb). We developed an innovative probe comprised of super-paramagnetic iron oxide (SPIO) nanoparticles conjugated with Mtb surface antibody (MtbsAb-nanoparticles) to provide ultrasensitive imaging of biomarkers involved in extrapulmonary Mtb infection. MtbsAb-nanoparticles were significantly conjugated with Mtb bacilli. The extent of contrast enhancement reduction on magnetic resonance imaging (MRI) for Mtb and human monocytic THP1 cells was proportional to the concentration of MtbsAb-nanoparticles. When MtbsAb-nanoparticles were intravenously injected into mice bearing Mtb granulomas, the granulomatous site showed a 14-fold greater reduction in signal intensity enhancement on T2-weighted MR images compared with an opposing site that received PBS injection. Mtb sAb-nanoparticles represent a new non-invasive technology for the diagnosis of extrapulmonary Mtb
Expression of ACTH-induced corticosteroid biosynthesis in newborn rat adrenocortical cells cultured in serum-free and carrier protein-free medium containing a cholesterol-?-cyclodextrin complex
No full textSimulation and monetization of collateral airborne infection risk improvements from ultraviolet germicidal irradiation for coil maintenance
No full textField measurement and modeling of UVC cooling coil irradiation for heating, ventilating, and air conditioning energy use reduction (RP-1738)—Part 2: Energy, indoor air quality, and economic modeling
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Super-paramagnetic iron oxide nanoparticles for use in extrapulmonary tuberculosis diagnosis
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