512 research outputs found

    Subatomic electronic feature from dynamic motion of Si dimer defects in Bi nanolines on Si(001)

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    Scanning tunneling microscopy (STM) reveals unusual sharp features in otherwise defect-free Bi nanolines self-assembled on Si(001). They appear as subatomic thin lines perpendicular to the Bi nanoline at positive biases and as atomic size beads at negative biases. Density functional theory (DFT) simulations show that these features can be attributed to buckled Si dimers substituting for Bi dimers in the nanoline, where the sharp feature is the counterintuitive signature of these dimers flipping during scanning. The perfect correspondence between the STM data and the DFT simulation demonstrated in this paper highlights the detailed understanding we have of the complex Bi-Si(001) Haiku system. This discovery has applications in the patterning of Si dangling bonds for nanoscale electronic

    Insight into the Charge Density Wave Gap from Contrast Inversion in Topographic STM Images

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    Charge density waves (CDWs) are understood in great detail in one dimension, but they remain largely enigmatic in two-dimensional systems. In particular, numerous aspects of the associated energy gap and the formation mechanism are not fully understood. Two long-standing riddles are the amplitude and position of the CDW gap with respect to the Fermi level ( E F ) and the frequent absence of CDW contrast inversion (CI) between opposite bias scanning tunneling microscopy (STM) images. Here, we find compelling evidence that these two issues are intimately related. Combining density functional theory and STM to analyze the CDW pattern and modulation amplitude in 1 T − TiSe 2 , we find that CI takes place at an unexpected negative sample bias because the CDW gap opens away from E F , deep inside the valence band. This bias becomes increasingly negative as the CDW gap shifts to higher binding energy with electron doping. This study shows the importance of CI in STM images to identify periodic modulations with a CDW and to gain valuable insight into the CDW gap, whose measurement is notoriously controversial

    Quantum authentication with key recycling

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    We show that a family of quantum authentication protocols introduced in [Barnum et al., FOCS 2002] can be used to construct a secure quantum channel and additionally recycle all of the secret key if the message is successfully authenticated, and recycle part of the key if tampering is detected. We give a full security proof that constructs the secure channel given only insecure noisy channels and a shared secret key. We also prove that the number of recycled key bits is optimal for this family of protocols, i.e., there exists an adversarial strategy to obtain all non-recycled bits. Previous works recycled less key and only gave partial security proofs, since they did not consider all possible distinguishers (environments) that may be used to distinguish the real setting from the ideal secure quantum channel and secret key resource.Comment: 38+17 pages, 13 figures. v2: constructed ideal secure channel and secret key resource have been slightly redefined; also added a proof in the appendix for quantum authentication without key recycling that has better parameters and only requires weak purity testing code

    Abschätzung der größenaufgelösten Partikelkonzentration und -zusammensetzung anhand wetterlagenorientierter experimenteller Messungen

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    Der Bericht "Abschätzung der größenaufgelösten Partikelkonzentration und -zusammensetzung anhand wetterlagenorientierter experimenteller Messungen" repräsentiert das REGKLAM-Produkt 2.2b. Auf der Grundlage von Experimenten wurde die heutige Situation analysiert und Szeanarien für einen Temperaturanstiegt sowie für eine Änderung der Anströmcharakteristik erarbeitet. Da die PM10-Massenkonzentrationen bereits heute Grenzwerte überschreiten und im Rahmen der klimatischen Veränderung nicht mit einer wesentlichen Abnahme zu rechnen ist, bleibt es auch zukünftig eine wichtige Herausforderung, die Emissionen von Partikeln und deren Vorläufersubstanzen sowohl in der Stadt als auch in der großräumigen Umgebung zu vermeiden

    Sexual Size Dimorphism and Body Condition in the Australasian Gannet

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    Funding: The research was financially supported by the Holsworth Wildlife Research Endowment. Acknowledgments We thank the Victorian Marine Science Consortium, Sea All Dolphin Swim, Parks Victoria, and the Point Danger Management Committee for logistical support. We are grateful for the assistance of the many field volunteers involved in the study.Peer reviewedPublisher PD

    A sex-chromosome mutation in Silene latifolia

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    Silene latifolia is dioecious, yet rare hermaphrodites have been found, and such natural mutants can provide valuable insight into genetic mechanisms. Here, we describe a hermaphrodite-inducing mutation that is almost certainly localized to the gynoecium-suppression region of the Y chromosome in S. latifolia. The mutant Y chromosome was passed through the megaspore, and the presence of two X chromosomes was not necessary for seed development in the parent. This result supports a lack of degeneration of the Y chromosome in S. latifolia, consistent with the relatively recent formation of the sex chromosomes in this species. When crossed to wild-type plants, hermaphrodites performed poorly as females, producing low seed numbers. When hermaphrodites were pollen donors, the sex ratio of offspring they produced through crosses was biased towards females. This suggests that hermaphroditic S. latifolia would fail to thrive and potentially explains the rarity of hermaphrodites in natural populations of S. latifolia. These results indicate that the Y chromosome in Silene latifolia remains very similar to the X, perhaps mostly differing in the primary sex determination regions

    Sodium Iodate Selectively Injuries the Posterior Pole of the Retina in a Dose-Dependent Manner: Morphological and Electrophysiological Study

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    Sequential morphological and functional features of retinal damage in mice exposed to different doses (40 vs. 20 mg/kg) of sodium iodate (NaIO3) were analyzed. Retinal morphology, apoptosis (TUNEL assay), and function (electroretinography; ERG) were examined at several time points after NaIO3 administration. The higher dose of NaIO3 caused progressive degeneration of the whole retinal area and total suppression of scotopic and photopic ERG. In contrast, the lower dose induced much less severe degeneration in peripheral part of retina along with a moderate decline of b- and a-wave amplitudes in ERG, corroborating the presence of regions within retina that retain their function. The peak of photoreceptor apoptosis was found on the 3rd day, but the lower dose induced more intense reaction within the central retina than in its peripheral region. In conclusion, these results indicate that peripheral area of the retina reveals better resistance to NaIO3 injury than its central part

    Exploring the Gain of Function Contribution of AKT to Mammary Tumorigenesis in Mouse Models

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    Elevated expression of AKT has been noted in a significant percentage of primary human breast cancers, mainly as a consequence of the PTEN/PI3K pathway deregulation. To investigate the mechanistic basis of the AKT gain of function-dependent mechanisms of breast tumorigenesis, we explored the phenotype induced by activated AKT transgenes in a quantitative manner. We generated several transgenic mice lines expressing different levels of constitutively active AKT in the mammary gland. We thoroughly analyzed the preneoplastic and neoplastic mammary lesions of these mice and correlated the process of tumorigenesis to AKT levels. Finally, we analyzed the impact that a possible senescent checkpoint might have in the tumor promotion inhibition observed, crossing these lines to mammary specific p53(R172H) mutant expression, and to p27 knock-out mice. We analyzed the benign, premalignant and malignant lesions extensively by pathology and at molecular level analysing the expression of proteins involved in the PI3K/AKT pathway and in cellular senescence. Our findings revealed an increased preneoplastic phenotype depending upon AKT signaling which was not altered by p27 or p53 loss. However, p53 inactivation by R172H point mutation combined with myrAKT transgenic expression significantly increased the percentage and size of mammary carcinoma observed, but was not sufficient to promote full penetrance of the tumorigenic phenotype. Molecular analysis suggest that tumors from double myrAKT;p53(R172H) mice result from acceleration of initiated p53(R172H) tumors and not from bypass of AKT-induced oncogenic senescence. Our work suggests that tumors are not the consequence of the bypass of senescence in MIN. We also show that AKT-induced oncogenic senescence is dependent of pRb but not of p53. Finally, our work also suggests that the cooperation observed between mutant p53 and activated AKT is due to AKT-induced acceleration of mutant p53-induced tumors. Finally, our work shows that levels of activated AKT are not essential in the induction of benign or premalignant tumors, or in the cooperation of AKT with other tumorigenic signal such as mutant p53, once AKT pathway is activated, the relative level of activity seems not to determine the phenotype
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