Guiding Transformation: How Medical Practices Can Become Patient-Centered Medical Homes

Describes in detail eight change concepts as a guide to transforming a practice into a patient-centered medical home, including engaged leadership, quality improvement strategy, continuous and team-based healing relationships, and enhanced access

Experience Corps: Effects on Student Reading

Experience Corps: Effects on Student Readin

3,121 Miles Away

Illustration of a map with a womans face in U.S.A and a mans fance in Ireland and an envelopehttps://scholarsjunction.msstate.edu/cht-sheet-music/9165/thumbnail.jp

Evaluation of Experience Corps: Student Reading Outcomes

Analyzes the impact of Experience Corps tutoring on elementary school students' reading comprehension as measured by four tests. Considers factors such as gender, race/ethnicity, grade, classroom behavior, English proficiency, and special education needs

ON the CONSERVATION of the VERTICAL ACTION in GALACTIC DISKS

We employ high-resolution N-body simulations of isolated spiral galaxy models, from low-amplitude, multi-armed galaxies to Milky Way-like disks, to estimate the vertical action of ensembles of stars in an axisymmetrical potential. In the multi-armed galaxy the low-amplitude arms represent tiny perturbations of the potential, hence the vertical action for a set of stars is conserved, although after several orbital periods of revolution the conservation degrades significantly. For a Milky Way-like galaxy with vigorous spiral activity and the formation of a bar, our results show that the potential is far from steady, implying that the action is not a constant of motion. Furthermore, because of the presence of high-amplitude arms and the bar, considerable in-plane and vertical heating occurs that forces stars to deviate from near-circular orbits, reducing the degree at which the actions are conserved for individual stars, in agreement with previous results, but also for ensembles of stars. If confirmed, this result has several implications, including the assertion that the thick disk of our Galaxy forms by radial migration of stars, under the assumption of the conservation of the action describing the vertical motion of stars. © 2016. The American Astronomical Society. All rights reserved

A focus on L dwarfs with trigonometric parallaxes

This is an author-created, un-copyedited version of an article published in Publications of the Astronomical Society of the Pacific. Under embargo until 14 May 2019. IOP Publishing Ltd is not responsible for any errors or omissions in this version of the manuscript or any version derived from it. The Version of Record is available online at https://doi.org/10.1088/1538-3873/aaacc5.We report new parallax measurements for ten L and early T type dwarfs, five of which have no previous published values, using observations over 3 years at the robotic Liverpool Telescope. The resulting parallaxes and proper motions have median errors of 2\,mas and 1.5\,mas/year respectively. Their space motions indicate they are all Galactic disk members. We combined this sample with other objects with astrometry from the Liverpool Telescope and with published literature astrometry to construct a sample of 260 L and early T type dwarfs with measured parallaxes, designated the Astrometry Sample. We study the kinematics of the Astrometry Sample, and derived a solar motion of $(U,V,W)_{\bigodot} = (7.9\pm1.7,13.2\pm1.2,7.2\pm1.0)$\,\kms~ with respect to the local standard of rest, in agreement with recent literature. We derive a kinematic age of 1.5-1.7\,Gyr for the Astrometry Sample assuming the age increases monotonically with the total velocity for a given disk sample. This kinematic age is less than half literature values for other low mass dwarf samples. We believe this difference arises for two reasons (1) the sample is mainly composed of mid to late L dwarfs which are expected to be relatively young and (2) the requirement that objects have a measured parallax biases the sample to the brighter examples which tend to be younger.Peer reviewedFinal Accepted Versio

Aerosol emission from the respiratory tract:an analysis of aerosol generation from oxygen delivery systems

INTRODUCTION: continuous positive airway pressure (CPAP) and high-flow nasal oxygen (HFNO) provide enhanced oxygen delivery and respiratory support for patients with severe COVID-19. CPAP and HFNO are currently designated as aerosol-generating procedures despite limited high-quality experimental data. We aimed to characterise aerosol emission from HFNO and CPAP and compare with breathing, speaking and coughing. MATERIALS AND METHODS: Healthy volunteers were recruited to breathe, speak and cough in ultra-clean, laminar flow theatres followed by using CPAP and HFNO. Aerosol emission was measured using two discrete methodologies, simultaneously. Hospitalised patients with COVID-19 had cough recorded using the same methodology on the infectious diseases ward. RESULTS: In healthy volunteers (n=25 subjects; 531 measures), CPAP (with exhalation port filter) produced less aerosol than breathing, speaking and coughing (even with large >50 L/min face mask leaks). Coughing was associated with the highest aerosol emissions of any recorded activity. HFNO was associated with aerosol emission, however, this was from the machine. Generated particles were small (<1 µm), passing from the machine through the patient and to the detector without coalescence with respiratory aerosol, thereby unlikely to carry viral particles. More aerosol was generated in cough from patients with COVID-19 (n=8) than volunteers. CONCLUSIONS: In healthy volunteers, standard non-humidified CPAP is associated with less aerosol emission than breathing, speaking or coughing. Aerosol emission from the respiratory tract does not appear to be increased by HFNO. Although direct comparisons are complex, cough appears to be the main aerosol-generating risk out of all measured activities

Using airborne LiDAR Survey to explore historic-era archaeological landscapes of Montserrat in the eastern Caribbean

This article describes what appears to be the first archaeological application of airborne LiDAR survey to historic-era landscapes in the Caribbean archipelago, on the island of Montserrat. LiDAR is proving invaluable in extending the reach of traditional pedestrian survey into less favorable areas, such as those covered by dense neotropical forest and by ashfall from the past two decades of active eruptions by the Soufrière Hills volcano, and to sites in localities that are inaccessible on account of volcanic dangers. Emphasis is placed on two aspects of the research: first, the importance of ongoing, real-time interaction between the LiDAR analyst and the archaeological team in the field; and second, the advantages of exploiting the full potential of the three-dimensional LiDAR point cloud data for purposes of the visualization of archaeological sites and features

Quantum entanglement for systems of identical bosons: I. General features

These two accompanying papers are concerned with two mode entanglement for systems of identical massive bosons and the relationship to spin squeezing and other quantum correlation effects. Entanglement is a key quantum feature of composite systems in which the probabilities for joint measurements on the composite sub-systems are no longer determined from measurement probabilities on the separate sub-systems. There are many aspects of entanglement that can be studied. This two-part review focuses on the meaning of entanglement, the quantum paradoxes associated with entangled states, and the important tests that allow an experimentalist to determine whether a quantum state—in particular, one for massive bosons is entangled. An overall outcome of the review is to distinguish criteria (and hence experiments) for entanglement that fully utilize the symmetrization principle and the super-selection rules that can be applied to bosonic massive particles. In the first paper (I), the background is given for the meaning of entanglement in the context of systems of identical particles. For such systems, the requirement is that the relevant quantum density operators must satisfy the symmetrization principle and that global and local super-selection rules prohibit states in which there are coherences between differing particle numbers. The justification for these requirements is fully discussed. In the second quantization approach that is used, both the system and the sub-systems are modes (or sets of modes) rather than particles, particles being associated with different occupancies of the modes. The definition of entangled states is based on first defining the non-entangled states—after specifying which modes constitute the sub-systems. This work mainly focuses on the two mode entanglement for massive bosons, but is put in the context of tests of local hidden variable theories, where one may not be able to make the above restrictions. The review provides the detailed arguments necessary for the conclusions of a recent paper, where the question of how to rigorously demonstrate the entanglement of a two-mode Bose–Einstein condensate (BEC) has been examined. In the accompanying review paper (II), we consider spin squeezing and other tests for entanglement that have been proposed for two-mode bosonic systems. We apply the approach of review (I) to determine which tests, and which modifications of the tests, are useful for detecting entanglement in massive bosonic (BEC), as opposed to photonic, systems. Several new inequalities are derived, a theory for the required two-mode interferometry is presented, and key experiments to date are analyzed

Mathematical modelling of polyamine metabolism in bloodstream-form trypanosoma brucei: An application to drug target identification

© 2013 Gu et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are creditedThis article has been made available through the Brunel Open Access Publishing Fund.We present the first computational kinetic model of polyamine metabolism in bloodstream-form Trypanosoma brucei, the causative agent of human African trypanosomiasis. We systematically extracted the polyamine pathway from the complete metabolic network while still maintaining the predictive capability of the pathway. The kinetic model is constructed on the basis of information gleaned from the experimental biology literature and defined as a set of ordinary differential equations. We applied Michaelis-Menten kinetics featuring regulatory factors to describe enzymatic activities that are well defined. Uncharacterised enzyme kinetics were approximated and justified with available physiological properties of the system. Optimisation-based dynamic simulations were performed to train the model with experimental data and inconsistent predictions prompted an iterative procedure of model refinement. Good agreement between simulation results and measured data reported in various experimental conditions shows that the model has good applicability in spite of there being gaps in the required data. With this kinetic model, the relative importance of the individual pathway enzymes was assessed. We observed that, at low-to-moderate levels of inhibition, enzymes catalysing reactions of de novo AdoMet (MAT) and ornithine production (OrnPt) have more efficient inhibitory effect on total trypanothione content in comparison to other enzymes in the pathway. In our model, prozyme and TSHSyn (the production catalyst of total trypanothione) were also found to exhibit potent control on total trypanothione content but only when they were strongly inhibited. Different chemotherapeutic strategies against T. brucei were investigated using this model and interruption of polyamine synthesis via joint inhibition of MAT or OrnPt together with other polyamine enzymes was identified as an optimal therapeutic strategy.The work was carried out under a PhD programme partly funded by Prof. Ray Welland, School of Computing Science, University of Glasgo