First Results from the X Ray Microscopy Beamline U41 PGM1 XM at BESSY II

The newly designed beamline U41 PGM1 XM at BESSY II for the Helmholtz Zentrum Berlin HZB transmission soft X ray microscope TXM was successfully set up and went in operation in 2017 [1]. During the commissioning of the beamline we determined the spectral resolution, horizontal focus value at the exit slit and the flux for different undulator harmonics. The experimental results meet the values from raytracing calculations. For the horizontal focus at the exit slit position we calculated a FWHM value of 108 m at 510 eV which is in good agreement with the experimental value of 107 m. The flux for photon energies higher than 550 eV is now much higher compared to the previous U41 SGM XM beamline [2] Fig.

An all-optical trap for a gram-scale mirror

We report on a stable optical trap suitable for a macroscopic mirror, wherein the dynamics of the mirror are fully dominated by radiation pressure. The technique employs two frequency-offset laser fields to simultaneously create a stiff optical restoring force and a viscous optical damping force. We show how these forces may be used to optically trap a free mass without introducing thermal noise; and we demonstrate the technique experimentally with a 1 gram mirror. The observed optical spring has an inferred Young's modulus of 1.2 TPa, 20% stiffer than diamond. The trap is intrinsically cold and reaches an effective temperature of 0.8 K, limited by technical noise in our apparatus.Comment: Major revision. Replacement is version that appears in Phy. Rev. Lett. 98, 150802 (2007

Treatment and control of bovine hypodermosis with ivermectin long-acting injection (IVOMEC® GOLD)

Background: The studies reported here were conducted to assess the efficacy of ivermectin long-acting injection (IVM LAI; IVOMEC® GOLD, Merial; 3.15 % w/v ivermectin) for the treatment and control of natural infestations of cattle by Hypoderma bovis and Hypoderma lineatum, which are the most economically important oestrid flies of cattle in the northern hemisphere. Methods: Cattle selected from herds with a history of Hypoderma infestation were grouped into blocks of three (Italy, 33 cattle; Germany, 30 cattle) or two (USA, 16 cattle) animals each, on the basis of positivity at the pre-treatment anti-Hypoderma antibody titres. Within each block, animals were randomly allocated to one of the following treatment regimens: saline (control); IVM LAI, administered at the predicted time of occurrence of first-instar larvae (Italy, Germany, USA); IVM LAI, administered at the predicted time of occurrence of second- and/or third-instar larvae (Italy, Germany). All treatments were administered by subcutaneous injection in correspondence of the area anterior to the shoulder at 1 ml/50 kg body weight, which corresponds to 630 mcg IVM/kg for IVM LAI. Results: No Hypoderma larvae emerged from animals treated with IVM LAI, whereas live H. lineatum (Italy) or H. bovis (Germany, USA) larvae were collected from saline-treated animals (P < 0.01). No adverse reactions to treatments were in any of the animals enrolled in the study. Conclusions: The results from this study demonstrate that ivermectin in a long-acting formulation is 100 % efficacious in the treatment of cattle naturally infested by H. bovis and H. lineatum larvae at all stages of development. IVM LAI can, therefore, be used as 'prophylactic' treatment for Hypoderma spp. infestations in absence of external evidence of their presence and thus prior to skin and carcass damage, and as 'therapeutic' treatment, when warbles are already present

Peanut agronomy experiments with five varieties in the Bundaberg and Kingaroy regions in the 2021-22 season

This report summarises the results of the peanut agronomy experiments conducted at Bundaberg and Kingaroy during the 2021-22 season as part of the above project. The experiments were laid out in a split-plot design with three replications at each location. Five peanut varieties, including Holt, Alloway, Kairi, Wheeler and P85-p112-151 (P85), were assigned to main plots, and four plant populations, 6, 12, 18, and 24 plants per m2, were assigned to subplots. All varieties were runner types except Wheeler, which represented a 'Virginia' type. Planting was done by the precision planting 20/20® and vSet® electronic seed metering system. The experiments were irrigated using irrigation scheduling software Aquaman via the web-based 'Yield Prophet'

A technological approach to the morphofunctional classification of seedlings of 50 Brazilian forest species.

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Demonstration of the metaphylactic use of gamithromycin against bacterial pathogens associated with bovine respiratory disease in a multicentre farm trial

On five commercial cattle rearing sites across Europe, a total of 802 young cattle at high risk of developing bovine respiratory disease (BRD) associated with the bacterial pathogens Mannheimia haemolytica or Pasteurella multocida and/or Mycoplasma bovis were enrolled into a multicentre, controlled field trial. Half were treated with a single dose of gamithromycin at 6 mg/kg bodyweight by subcutaneous injection and half received an injection of a saline placebo as the control. All animals were observed daily for 14 days for signs of BRD as defined by set criteria. The proportion of metaphylactic preventive treatment successes, defined as animals surviving to day 14 without signs of BRD, in the gamithromycin-treated group (86 per cent) was significantly (P=0.0012) higher than in the saline-treated controls (61 per cent). Morbidity among the treated animals was reduced by 64 per cent compared with the controls

Tensile Overload and Stress Intensity Shielding Investigations by Ultrasound

Growth of a fatigue crack is modified according to the development of contacts between the crack faces [1,2] creating shielding, thus canceling a portion of the crack driving force. These contacts develop through a number of mechanisms, including plastic deformation, sliding of the faces with respect to each other and the collection of debris such as oxide particles [3]. Compressive stresses are created on either side of the partially contacting crack faces resulting in opening loads that must be overcome in order to apply a driving force at the crack tip. In this way, the crack tip is shielded from a portion of the applied load, thus creating the need for modification [1] of the applied stress intensity range from ΔK = KImax − KImin to ΔKeff = KImax − KIsh. Determination of the contact size and density in the region of closure from ultrasonic transmission and diffraction experiments [4] has allowed estimation of the magnitude of Kish on a crack grown under constant ΔK conditions. The calculation has since [5] been extended to fatigue cracks grown with a tensile overload block. The calculation was also successful in predicting the growth rate of the crack after reinitiation had occurred. This paper reports the further extension to the effects of a variable ΔK on fatigue crack growth. In addition, this paper presents preliminary results on detection of the tightly closed crack extension present during the growth retardation period after application of a tensile overload as well as an observation of the crack surface during reinitiation of growth that presents some interesting questions

Characterization of Microstructural Effects on Fatigue Crack Closure

The growth of a fatigue crack is modified by the development of contacts between the crack faces1,2creating shielding and thus canceling a portion of the applied load. These contacts develop through a number of mechanisms, including plastic deformation, sliding of the faces with respect to each other and the creation and collection of debris such as oxide particles3. Compressive stresses are created on either side of the partially contacting crack faces resulting in opening loads that must be overcome in order to apply a driving force to the crack tip for growth. In this way, the crack tip is shielded from a portion of the applied load, thus creating the need for modification1 of the applied stress intensity range from ΔK = KImax — KImin to ΔK = KImax — KIsh. Determination of the contact size and density in the region of closure from ultrasonic transmission and diffraction experiments4has allowed estimation of the magnitude of KIsh on a crack grown under constant ΔK conditions. The calculation has since5 been extended to fatigue cracks grown with a tensile overload block. The calculation was also successful in predicting the growth rate of the crack after reinitiation had occurred. This paper reports the results of attempts to define the amount of retardation remaining before reinitiation of crack growth in terms of the parameters used by the distributed spring model

Achieving ground state and enhancing entanglement by recovering information

For cavity-assisted optomechanical cooling experiments, it has been shown in the literature that the cavity bandwidth needs to be smaller than the mechanical frequency in order to achieve the quantum ground state of the mechanical oscillator, which is the so-called resolved-sideband or good-cavity limit. We provide a new but physically equivalent insight into the origin of such a limit: that is information loss due to a finite cavity bandwidth. With an optimal feedback control to recover those information, we can surpass the resolved-sideband limit and achieve the quantum ground state. Interestingly, recovering those information can also significantly enhance the optomechanical entanglement. Especially when the environmental temperature is high, the entanglement will either exist or vanish critically depending on whether information is recovered or not, which is a vivid example of a quantum eraser.Comment: 9 figures, 18 page

Using the EngagedMD Multimedia Platform to Improve Informed Consent for Ovulation Induction, Intrauterine Insemination, and In Vitro Fertilization

Objective: To study patient and provider feedback on how a multimedia platform (EngagedMD) helps patients to understand the risks and consequences of in vitro fertilization (IVF), ovulation induction (OI), and intrauterine insemination (IUI) treatments and the impact of the informed consent process. Design: Prospective survey study. Setting: IVF units in the United States. Patient(s): Six-thousand three-hundred and thirty-three patients who viewed the multimedia platform before IVF or OI-IUI treatment at 13 U.S. IVF centers and 128 providers. Intervention(s): Quantitative survey with 17 questions. Main Outcome Measure(s): Assessment of the impact of a multimedia platform on patient anxiety, comprehension, and satisfaction and provider/nurse feedback related to the informed consent process. Result(s): The survey was completed by 3,097 respondents (66% IVF treatment; 34% OI-IUI treatment) and 44 providers. Overall, 93% felt the media platform was intuitive, and 90% and 95% felt it had appropriate duration and detail, respectively. Most agreed/strongly agreed it better prepared them to consent (88%), increased their comfort in pursuing treatment (77%) and increased their satisfaction with their care (83%). Compared with the OI-IUI group, statistically significantly more participants who viewed the IVF media platform strongly agreed that the comprehension questions reinforced key concepts (47% vs. 40%), educated them about treatment risks (55% vs. 44%), helped them ask providers informed questions (45% vs. 36%), and better prepared them to sign consent forms (46% vs. 37%). Overall, 63% of providers felt that the media platform improved patient learning, made patients more accountable, and standardized information dissemination. Conclusion(s): The EngagedMD media platform improves patient knowledge, satisfaction, and control over medical decision making and better prepares patients to give informed consent. Furthermore, it is well-liked by providers and is easily implemented