PENGARUH STRUKTUR KEPEMILIKAN DAN ARUS KAS TERHADAP FINANCIAL DISTRESS (Studi Empiris pada Perusahaan Manufaktur yang Terdaftar di Bursa Efek Indonesia Tahun 2010-2014)

This study aims to examine the effect of the ownership structures and cash flows on the financial distress. Indicators used to measure ownership structures are ownership concentration, government ownership, and managerial ownership. The cash flows used are cash flow from operating activities, cash flow from investing activities, and cash flow from financing activities. The population are manufacturing companies listed in Indonesia Stock Exchange for period of 2010-2014. Based on the purposive sampling method, there are 162 companies observed that consist of 81 financial distress and 81 non financial distress companies. The criteria used to categorize a financial distress companies was based on Altman Z-score statistical model 1968. Logistic regression by SPSS 21 used to analysis data. The result showed that the ownership concentration, managerial ownership, cash flow operating activities, and cash flow from financing activities have significant effect on financial distress. While government ownership and cash flow from investing activities have no effect on financial distress

Structural studies of PMM/PGM from Pseudomonas aeruginosa

The entire dissertation/thesis text is included in the research.pdf file; the official abstract appears in the short.pdf file (which also appears in the research.pdf); a non-technical general description, or public abstract, appears in the public.pdf file.Title from title screen of research.pdf file (viewed on October 18, 2007)Vita.Includes bibliographical references.Thesis (Ph. D.) University of Missouri-Columbia 2005.Dissertations, Academic -- University of Missouri--Columbia -- Biochemisty (Agriculture)The human pathogen Pseudomonas aeruginosa expresses a variety of cell surface polysaccharides, including alginate, lipopolysaccharide (LPS), and rhamnolipid. P. aeruginosa is the primary cause of chronic lung infections in cystic fibrosis (CF) patients, and these molecules contribute to its virulence. This dual-specificity enzyme phosphomannomutase/phosphoglucomutase (PMM/PGM) is required for the production of these molecules. The structure of PMM/PGM was previously solved in our laboratory, showing that the protein has four domains organized in a "heart shape," with the active site in a deep cleft formed by residues from each domain. Recently, we have determined the structures of PMM/PGM bound to its two substrates, two products, and an intermediate at 2.0 Å resolution or higher. These structures reveal the structural basis for diverse substrate recognition by the enzyme and pinpoint residues important for accomplishing the dynamic reorientation step of the reaction

Confini, soglie e limiti. Leggere Virginia Woolf e Ingeborg Bachmann attraverso Michail Bachtin

La categoria del confine, rielaborata da Bachtin a partire dalle scienze naturali, se da un lato è funzionale per fare luce sulle esperienze biografiche così come sul pensiero del teorico russo, è strumento privilegiato per analizzare le opere di Virginia Woolf e Ingeborg Bachmann, due autrici che, anche se in modi e tempi diversi, hanno contribuito a trasformare il volto della letteratura novecentesca, sviluppando una poetica delle zone liminali e tracciando sentieri letterari unici. Il confine, potente luogo cronotopico, si esprime così in un complesso insieme di immagini letterarie. Se nel capolavoro modernista di Woolf To the Lighthouse confini e soglie, porte e finestre dialogano e l’esperienza della morte si sviluppa in un rito liminale tra il passato e il futuro della famiglia Ramsey, nelle opere di Bachmann, autrice che proviene dal confine, si rintraccia un fecondo universo di elementi liminali tra cui il ponte, il fiume, la partenza, il viaggio nelle prime raccolte di poesie, ma soprattutto la figura di Undine, creatura acquatica che tra terra e mare pronuncia il suo accorato addio

The sustainable reuse of compost from a new type of olive mill pomace in replacing peat for potted olive tree

The attention for the replacement of peat in growing substrates is increasing due to its environmental and economic advantages. The aim of the present work was to evaluate the impact of peat substitution by new type olive mill pomace and its compost on the vegetative activity of potted olive trees. A new type of humid pomace (hP) derived from an innovative two phase extraction system and its derived compost (C-hP) are used as total or partial (50% vol/vol) replacement of peat in olive growing substrate. The main chemical characteristics (moisture, water extractable organic carbon, total nitrogen, C/N ratio and electrical conductivity) of the hP and C-hP were measured. In order to evaluate the effects of the peat substitution on the plants vegetative activity, measurements of mortality, plant height, leaf net photosynthesis and plant growth (through final destructive measurements) were carried out. The use of hP resulted in a significant increase of the salinity of the substrate. The water extractable organic carbon concentration was higher in all substrates where peat was ewplaced and in particular when C-hP was used. The total replacement of peat with hP caused 100% mortality of the plants while C-hP can substitute peat up to 50% without causing a significative reduction of the final plant growth

Asymmetric Total Synthesis of All Rugulovasine Stereoisomers and Preliminary Evaluation of Their Biological Properties

A unified enantioselective synthesis and the biological evaluation of all rugulovasine stereoisomers are reported. The syntheses are centered on the divergent and stereochemical modular combination of each enantiomer of 4-amino Uhle's ketone and a methacrylate derivative to build the unsaturated oxaspirolactone moiety by the Dreiding-Schmidt reaction, followed by Fukuyama alkylation to afford the required N-methyl secondary amine in excellent yield. The modularity of this divergent approach, the diastereoselectivities of the reactions, and the late-stage site-selective methylation permit the rapid asymmetric syntheses of all rugulovasine stereoisomers, including the first total syntheses of optically pure (+)- and (−)-rugulovasine B and their trideuteromethylated derivatives. All enantiopure stereoisomers of rugulovasine were tested for their binding affinities to dopamine, serotonin, and adrenergic neuroreceptors, revealing their preferred selectivity for the serotonin 1 A receptor

Planting Systems for Modern Olive Growing: Strengths and Weaknesses

The objective of fully mechanizing olive harvesting has been pursued since the 1970s to cope with labor shortages and increasing production costs. Only in the last twenty years, after adopting super-intensive planting systems and developing appropriate straddle machines, a solution seems to have been found. The spread of super-intensive plantings, however, raises serious environmental and social concerns, mainly because of the small number of cultivars that are currently used (basically 2), compared to over 100 cultivars today cultivated on a large scale across the world. Olive growing, indeed, insists on over 11 million hectares. Despite its being located mostly in the Mediterranean countries, the numerous olive growing districts are characterized by deep differences in climate and soil and in the frequency and nature of environmental stress. To date, the olive has coped with biotic and abiotic stress thanks to the great cultivar diversity. Pending that new technologies supporting plant breeding will provide a wider number of cultivars suitable for super-intensive systems, in the short term, new growing models must be developed. New olive orchards will need to exploit cultivars currently present in various olive-growing areas and favor increasing productions that are environmentally, socially, and economically sustainable. As in fruit growing, we should focus on “pedestrian olive orchards”, based on trees with small canopies and whose top can be easily reached by people from the ground and by machines (from the side of the top) that can carry out, in a targeted way, pesticide treatments, pruning and harvesting

Application of Encapsulation Technology: In Vitro Screening of Two Ficus carica L. Genotypes under Different NaCl Concentrations

Salinity stress represents an increasing issue for agriculture and has a great negative impact on plant growth and crop production. The selection of genotypes able to tolerate salt stress could be a suitable solution to overcome the problem. In this context, in vitro cultures can represent a tool for identifying the NaCl tolerant genotypes and quickly producing large populations of them. The possibility of exerting selection for tolerance to NaCl by using encapsulation technology was investigated in two genotypes of fig: 'Houmairi' and 'Palazzo'. The effects of five concentrations of NaCl (0, 50, 100, 150 and 200 mM) added to the artificial endosperm were tested on the conversion of synthetic seeds and on the growth of derived shoots/plantlets. Moreover, proline (Pro) and malondialdehyde (MDA), the enzymatic activities of catalase (CAT), guaiacol peroxidase (POD), and EL (Electrolytic Leakage), as well as the chlorophyll content, flavanols, anthocyanins, and Nitrogen Balance Index (NBI) were determined on shoots/plantlet. The obtained results clearly showed that 'Houmairi' and 'Palazzo' could tolerate salt stress, although a strong difference was found depending on each specific physiological pathway. Indeed, 'Houmairi' was revealed to be more tolerant than 'Palazzo', with different response mechanisms to salt stress. The use of encapsulated vitro-derived explants proved to be a useful method to validate the selection of genotypes tolerant to salinity stress. Further investigation in the field must validate and confirm the legitimacy of the approach