246 research outputs found

    Studi Difraksi Neutron Pada Fasa Hijau Y2bacuo5

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    STUDI DIFRAKSI NEUTRON PADA FASA HIJAU Y2BaCuO5. Studi difraksi neutron pada fasa hijau Y2BaCuO5 telah dilakukan dengan metode Rietveld. Hasil analisis menunjukkan bahwa fasa hijau Y2BaCuO5 telah mengkristal ke dalam sistem ortorombik dengan grup ruang Pnma, No. 62, parameter kisi : a = 12,184(3) Ã…, b = 5,662(1) Ã…, c = 7,135(2) Ã…, volume sel satuan V = 492,3(2) Ã…3 dan kerapatan D = 6,132 g/cm3 dan terdapat kekosongan pada titik tempat atom Y dan Cu. Vibrasi termal terkuat kedua atom Y1 dan Y2 adalah pada arah sumbu-y berturut-turut dengan parameter suhu U22 = 12(5) dan 11(4) x10-3Ã…2. Pada arah sumbu-x terjadi vibrasi yang lebih kuat bagi atom Ba dengan parameter suhu U11 = 17(1) x10-3Ã…2. Harga parameter suhu terbesar bagi atom Cu adalah U22 = 9(5) x10-3Ã…2. Ini berarti pada arah sumbu-y terjadi vibrasi yang lebih kuat bagi atom Cu. Besar atau kecilnya parameter suhu sebuah atom, terkait dengan ukuran dan bentuk rongga tempat kedudukan atom tersebut di dalam sel satuan. Jadi ukuran dan bentuk rongga yang secara sistematis membatasi vibrasi termal atom-atom di dalam kristal

    Statin Use and Venous Thromboembolism in Cancer: A Large, Active Comparator, Propensity Score Matched Cohort Study

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    Background—Statins have been shown to have a protective effect for venous thromboembolism (VTE) in the general population. This study sought to assess the association between statins and the risk for cancer-associated deep vein thrombosis (DVT) and pulmonary embolism (PE). Methods—Patients with newly diagnosed cancer were followed for up to one year in a healthcare claims database (2010–2013). Three treatment groups included statin users, non-statin cholesterol lowering medication users, and an untreated group with pre-existing indications for statin therapy (hyperlipidemia, diabetes, or heart disease). Propensity score matched groups were compared using competing risks survival models for DVT and PE outcomes reporting the hazard ratios (HR) between the treatment groups. Sensitivity analyses assessed the influence of age and individual medications. Results—The total cohort included 170,459 patients, which, after matching, were similar on baseline characteristics. The overall model showed a statistically significant protective effect for statins compared to no treatment attributed only to leukemia for DVT (HR = 0.77, 95% CI 0.61–0.99) and colorectal cancers for PE (HR = 0.80, 95% CI 0.64–0.99) in stratified analyses. There were generally no differences in outcomes between statins and non-statins and no individual statin use showed results different from the class effect. Conclusions—In this propensity score matched sample of patients with cancer, statins were shown to have a small protective effect in some cancers for DVT or PE compared to no treatment and little difference compared to an active control group. The lack of effect was consistent across statins and was also not found for any of the sensitivity analyses included

    GG-prime and GG-primary GG-ideals on GG-schemes

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    Let GG be a flat finite-type group scheme over a scheme SS, and XX a noetherian SS-scheme on which GG-acts. We define and study GG-prime and GG-primary GG-ideals on XX and study their basic properties. In particular, we prove the existence of minimal GG-primary decomposition and the well-definedness of GG-associated GG-primes. We also prove a generalization of Matijevic-Roberts type theorem. In particular, we prove Matijevic-Roberts type theorem on graded rings for FF-regular and FF-rational properties.Comment: 54pages, added Example 6.16 and the reference [8]. The final versio

    International Journal of Entrepreneurship & Innovation Editors Series

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    We are delighted to introduce another collection of excellent papers for this edition of IJEI. In addition, we present here also the first in our series of editors’ notes to support authors and their publishing ambitions

    STUDI DIFRAKSI NEUTRON PADA FASA HIJAU Y2BaCuO5

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    STUDI DIFRAKSI NEUTRON PADA FASA HIJAU Y2BaCuO5. Studi difraksi neutron pada fasa hijau Y2BaCuO5 telah dilakukan dengan metode Rietveld. Hasil analisis menunjukkan bahwa fasa hijau Y2BaCuO5 telah mengkristal ke dalam sistem ortorombik dengan grup ruang Pnma, No. 62, parameter kisi : a = 12,184(3) Ã…, b = 5,662(1) Ã…, c = 7,135(2) Ã…, volume sel satuan V = 492,3(2) Ã…3 dan kerapatan D = 6,132 g/cm3 dan terdapat kekosongan pada titik tempat atom Y dan Cu. Vibrasi termal terkuat kedua atom Y1 dan Y2 adalah pada arah sumbu-y berturut-turut dengan parameter suhu U22 = 12(5) dan 11(4) x10-3Ã…2. Pada arah sumbu-x terjadi vibrasi yang lebih kuat bagi atom Ba dengan parameter suhu U11 = 17(1) x10-3Ã…2. Harga parameter suhu terbesar bagi atom Cu adalah U22 = 9(5) x10-3Ã…2. Ini berarti pada arah sumbu-y terjadi vibrasi yang lebih kuat bagi atom Cu. Besar atau kecilnya parameter suhu sebuah atom, terkait dengan ukuran dan bentuk rongga tempat kedudukan atom tersebut di dalam sel satuan. Jadi ukuran dan bentuk rongga yang secara sistematis membatasi vibrasi termal atom-atom di dalam kristal

    Neurofilament light chain levels in ventricular cerebrospinal fluid after acute aneurysmal subarachnoid haemorrhage

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    PURPOSE: The contribution of axonal injury to brain damage after aneurysmal subarachnoid haemorrhage (aSAH) is unknown. Neurofilament light chain (NF-L), a component of the axonal cytoskeleton, has been shown to be elevated in the cerebrospinal fluid of patients with many types of axonal injury. We hypothesised that patients with aSAH would have elevated cerebrospinal fluid (CSF) NF-L levels and sought to explore the clinical correlates of CSF NF-L dynamics. METHODS: Serial ventricular CSF (vCSF) samples were collected from 35 patients with aSAH for up to 15 days. vCSF NF-L measurements were determined by enzyme-linked immunosorbent assay. NF-L levels were analysed in relation to acute clinical status, radiological findings and 6-month outcomes. RESULTS: vCSF NF-L concentrations were elevated in all patients with aSAH. Patients with early cerebral ischaemia (ECI), defined as a CT hypodense lesion visible within the first 3 days, had higher acute vCSF NF-L levels than patients without ECI. These elevated NF-L levels were similar in patients with ECI associated with intracranial haemorrhage and ECI associated with surgical/endovascular complications. vCSF NF-L levels did not differ as a function of acute clinical status, clinical vasospasm, delayed cerebral ischaemia or 6-month Glasgow Outcome Scale. CONCLUSIONS: Elevated vCSF NF-L levels may in part reflect increased injury to axons associated with ECI. However, our results suggest that axonal injury after aSAH as reflected by release of NF-L into the CSF may not play a major role in either secondary adverse events or long-term clinical outcome

    ISOLATION OF Cryptococcus neoformans FROM ENVIRONMENTAL SAMPLES COLLECTED IN SOUTHEASTERN NIGERIA

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    SUMMARY Cryptococcosis caused by Cryptococcus neoformans is the second most common fungal opportunistic pathogen and a lifethreatening infection with serious clinical manifestations especially in HIV/AIDS and other immunocompromised patients. In Nigeria, HIV/AIDS infection has reached an alarming level. Despite this, information on the presence of this fungus in clinical and environmental samples is very scanty in Nigeria and many other parts of Africa. We set out to evaluate the presence of Cryptococcus neoformans or C. gattii in pigeon droppings obtained from Southeastern Nigeria. One hundred and seventy-seven samples of pigeon droppings from six sample types were collected. The area covered comprised of ten cities and other locations spanning across five States in Nigeria. Using established techniques, Cryptococcus neoformans was isolated from 39 of the 177 (22.0%) samples overall. No C. gattiiwas isolated. Most of the isolates (32.4%) were recovered from dovecotes (11 of 34) followed closely by samples taken from markets (31.8%; seven of 22) and least from the church (4.0%; one of 25). The highest isolation rate (38.9%) was found in samples from Enugu-Ezike(seven of 23) while the least came from Afikpoand the other locations each with 9.1% isolation rate. This is the first large-scale screening of Cryptococcus neoformans from pigeon droppings in Nigeria. The ecological and epidemiological significance of these findings are discussed

    Risk of intracranial haemorrhage and ischaemic stroke after convexity subarachnoid haemorrhage in cerebral amyloid angiopathy: international individual patient data pooled analysis

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    OBJECTIVE: To investigate the frequency, time-course and predictors of intracerebral haemorrhage (ICH), recurrent convexity subarachnoid haemorrhage (cSAH), and ischemic stroke after cSAH associated with cerebral amyloid angiopathy (CAA). METHODS: We performed a systematic review and international individual patient-data pooled analysis in patients with cSAH associated with probable or possible CAA diagnosed on baseline MRI using the modified Boston criteria. We used Cox proportional hazards models with a frailty term to account for between-cohort differences. RESULTS: We included 190 patients (mean age 74.5 years; 45.3% female) from 13 centers with 385 patient-years of follow-up (median 1.4 years). The risks of each outcome (per patient-year) were: ICH 13.2% (95% CI 9.9-17.4); recurrent cSAH 11.1% (95% CI 7.9-15.2); combined ICH, cSAH, or both 21.4% (95% CI 16.7-26.9), ischemic stroke 5.1% (95% CI 3.1-8) and death 8.3% (95% CI 5.6-11.8). In multivariable models, there is evidence that patients with probable CAA (compared to possible CAA) had a higher risk of ICH (HR 8.45, 95% CI 1.13-75.5, p = 0.02) and cSAH (HR 3.66, 95% CI 0.84-15.9, p = 0.08) but not ischemic stroke (HR 0.56, 95% CI 0.17-1.82, p = 0.33) or mortality (HR 0.54, 95% CI 0.16-1.78, p = 0.31). CONCLUSIONS: Patients with cSAH associated with probable or possible CAA have high risk of future ICH and recurrent cSAH. Convexity SAH associated with probable (vs possible) CAA is associated with increased risk of ICH, and cSAH but not ischemic stroke. Our data provide precise risk estimates for key vascular events after cSAH associated with CAA which can inform management decisions
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