Multidisciplinary Investigations at P.O.W. Camp 198, Bridgend, S. Wales: Site of a Mass Escape in March 1945

The largest escape of German Prisoner of War (P.O.W.) in WW2 was in March 1945 from Camp 198, situated in Bridgend, South Wales, UK. Since camp closure the site has become derelict, and has not been scientifically investigated. This paper reports on the search to locate the P.O.W. escape tunnel that was dug from Hut 9. This hut remains in remarkable condition, with numerous P.O.W. graffiti still present. Also preserved is a prisoner-constructed false wall in a shower room behind which excavated material was hidden, though the tunnel entrance itself has been concreted over. Near-surface geophysics and ground-based LiDAR were used to locate the tunnel. Mid-frequency GPR surveys were judged optimal, with magnetometry least useful due to the above-ground metal objects. Archaeological excavations discovered the intact tunnel and bed-board shoring. With Allied P.O.W. escape camp attempts well documented, this investigation provides valuable insight into German escape efforts

Extreme Mass Ratio Inspirals: LISA's unique probe of black hole gravity

In this review article I attempt to summarise past and present-ongoing-work on the problem of the inspiral of a small body in the gravitational field of a much more massive Kerr black hole. Such extreme mass ratio systems, expected to occur in galactic nuclei, will constitute prime sources of gravitational radiation for the future LISA gravitational radiation detector. The article's main goal is to provide a survey of basic celestial mechanics in Kerr spacetime and calculations of gravitational waveforms and backreaction on the small body's orbital motion, based on the traditional `flux-balance' method and the Teukolsky black hole perturbation formalism.Comment: Invited review article, 45 pages, 23 figure

"Kludge" gravitational waveforms for a test-body orbiting a Kerr black hole

One of the most exciting potential sources of gravitational waves for low-frequency, space-based gravitational wave (GW) detectors such as the proposed Laser Interferometer Space Antenna (LISA) is the inspiral of compact objects into massive black holes in the centers of galaxies. The detection of waves from such "extreme mass ratio inspiral" systems (EMRIs) and extraction of information from those waves require template waveforms. The systems' extreme mass ratio means that their waveforms can be determined accurately using black hole perturbation theory. Such calculations are computationally very expensive. There is a pressing need for families of approximate waveforms that may be generated cheaply and quickly but which still capture the main features of true waveforms. In this paper, we introduce a family of such "kludge" waveforms and describe ways to generate them. We assess performance of the introduced approximations by comparing "kludge" waveforms to accurate waveforms obtained by solving the Teukolsky equation in the adiabatic limit (neglecting GW backreaction). We find that the kludge waveforms do extremely well at approximating the true gravitational waveform, having overlaps with the Teukolsky waveforms of 95% or higher over most of the parameter space for which comparisons can currently be made. Indeed, we find these kludges to be of such high quality (despite their ease of calculation) that it is possible they may play some role in the final search of LISA data for EMRIs.Comment: 29 pages, 11 figures, requires subeqnarray; v2 contains minor changes for consistency with published versio

Unveiling buried aeolian landscapes: reconstructing a late Holocene dune environment using 3D ground-penetrating radar

Across the UK, sandy beaches and dunes protect coastal infrastructure from waves and extreme water levels during large-scale storms, while providing important habitats and recreational opportunities. Understanding their long-term evolution is vital in managing their condition in a changing climate. Recently, ground-penetrating radar (GPR) methods have grown in popularity in geomorphological applications, yielding centimetre-scale resolution images of near-surface stratigraphy and structure, thus allowing landscape evolution to be reconstructed. Additionally, abrupt changes in palaeo-environments can be visualized in three dimensions. Although often complemented by core data, GPR allows interpretations to be extended into areas with minimal ground-truth control. Nonetheless, GPR data interpretation can be non-intuitive and ambiguous, and radargrams may not initially resemble the expected subsurface geometry. Interpretation can be made yet more onerous when handling the large 3D data volumes that are facilitated with modern GPR technology. Here we describe the development of novel semi-automated GPR feature-extraction tools, based on ‘edge detection’ and ‘thresholding’ methods, which detect regions of increased GPR reflectivity which can be applied to aid in the reconstruction of a range Quaternary landscapes. Since reflectivity can be related to lithological and/or pore fluid changes, the 3D architecture of the palaeo-landscape can be reconstructed from the features extracted from a geophysical dataset. We present 500 MHz GPR data collected over a buried Holocene coastal dune system in North Wales, UK, now reclaimed for use as an airfield. Core data from the site, reaching a maximum depth 2 m, suggest rapid vertical changes from sand to silty-organic units, and GPR profiles suggest similar lateral complexity. By applying thresholding methods to GPR depth slices, these lateral complexities are effectively and automatically mapped. Furthermore, automatic extraction of the local reflection power yields a strong correlation with the depth variation of organic content, suggesting it is a cause of reflectivity contrast. GPR-interpolated analyses away from core control thus offer a powerful proxy for parameters derived from invasive core logging. The GPR data collected at Llanbedr airfield highlight a complex dune system to a depth of 2.8 m, probably deposited in several phases over ~700 years, similar to elsewhere in North Wales

Where is your office today? A research-led guide to effective hybrid working

This is the final version. Available from the University of Leeds via the link in this recordThis research examines the changes to workplaces and ways of working spurred by the COVID-19 pandemic. We aim to understand the implications of the changes: learn lessons, share good practice, and provide guidance for organisations adopting hybrid working or adapting offices to support their future ways of working. In this interactive report, we share insights from a range of stakeholder and employee interviews, industry workshops, cross-industry surveys of UK office workers, employee diary data and reviews of published guidance and case studies.Economic and Social Research Council (ESRC

Postcolonial Transplants: Cinema, Diaspora and the Body Politic

This essay examines depictions of migrant workers in French and British postcolonial cinema as transplanted interlopers, 'exotic' or transgendered bodies that are perceived as a threat to the integrity of the body politic

OA01-06 LB. HIV-1 plasma RNA and risk of HIV-1 transmission

Background: Non-sterilizing HIV-1 vaccines may provide public health benefits if they significantly reduce plasma HIV-1 RNA, thus potentially reducing infectiousness. Quantification of reduction in plasma HIV-1 RNA needed to decrease HIV-1 transmission is useful for design of efficacy trials of candidate HIV-1 vaccines. We modeled the relationship between plasma HIV-1 RNA and HIV-1 transmission using data from a prospective study of African heterosexual HIV-1 serodiscordant couples. Methods: 3408 HIV-1-infected participants with CD4 counts ≥250 cells/mm3 enrolled in the Partners in Prevention HSV/HIV Transmission Study and their partners were followed for ≤24 months. HIV-1 transmission events were assessed for viral genetic linkage within the enrolled partnership by determining HIV-1 env and gag sequences from partners. The relationship between plasma HIV-1 RNA over time and risk of genetically linked HIV-1 transmission was evaluated with a Cox model with a natural cubic spline. Results: 84 post-enrollment linked HIV-1 transmissions were observed. HIV-1 incidence increased rapidly and non-linearly with higher plasma HIV-1: from 0.53 transmissions per 100 person-years for plasma HIV-1 RNA 1,000,000 copies/mL (p<0.0001). Baseline HIV-1 RNA in men was, on average, 0.4 log10 higher than in women; no significant difference in risk of transmission for a given HIV-1 level was observed between men and women (p = 0.17). Given the distribution of plasma HIV-1 RNA in this population of stable cohabiting couples, our modeling predicts that a 0.74 log10 reduction in average plasma HIV-1 RNA in the population would be required for a 50% reduction in HIV-1 transmission risk. Conclusion: This analysis provides a detailed description of the relationship between plasma HIV-1 RNA and risk of heterosexual HIV-1 transmission. These findings suggest targets for reduction in HIV-1 RNA for use in evaluating non-sterilizing HIV-1 vaccine candidates in HIV-1 infected persons to reduce risk of heterosexual HIV-1 transmission

Where is your Office Today? New insights on Employee Behaviour and Social Networks

This is the second of two reports sharing key findings and suggestions for how to approach the challenge of adapting organisations to hybrid and more flexible ways of working. This report focuses on the impact that different work patterns and workplaces have on employees (wellbeing, job satisfaction, performance, interactions), and what this means for organisations and future workplaces. Findings from analysis of employee diaries, surveys and social network analysis are shared. Differences between groups of workers (e.g. new starters, different generations) under different work patterns (e.g. office vs home vs hybrid) and in different office workspaces (e.g. open plan vs social spaces vs private workspaces) are examined. The research data is presented to help managers take evidence based decisions about their work polices and workplaces. Practical guides are included to help both managers and employees understand how they can apply social network principles to support career development, productivity and knowledge sharing. The report concludes with a reflection on the opportunities that the future workplace presents, and ideas for how to implement viable hybrid working

Developing ovine mammary terminal duct lobular units have a dynamic mucosal and stromal immune microenvironment

Funder: University of Cambridge | Girton College, University of Cambridge (Girton); doi: https://doi.org/10.13039/501100000621Funder: University of Cambridge Herchel-Smith FundFunder: British Veterinary Association Animal Welfare Foundation Norman Hayward Fund ref NHF_2016_03_KHAbstract: The human breast and ovine mammary gland undergo striking levels of postnatal development, leading to formation of terminal duct lobular units (TDLUs). Here we interrogate aspects of sheep TDLU growth as a model of breast development and to increase understanding of ovine mammogenesis. The distributions of epithelial nuclear Ki67 positivity differ significantly between younger and older lambs. Ki67 expression is polarised to the leading edge of the developing TDLUs. Intraepithelial ductal macrophages exhibit periodicity and considerably increased density in lambs approaching puberty. Stromal macrophages are more abundant centrally than peripherally. Intraepithelial T lymphocytes are more numerous in older lambs. Stromal hotspots of Ki67 expression colocalize with immune cell aggregates that exhibit distinct organisation consistent with tertiary lymphoid structures. The lamb mammary gland thus exhibits a dynamic mucosal and stromal immune microenvironment and constitutes a valuable model system that provides new insights into postnatal breast development

Measuring gravitational waves from binary black hole coalescences: I. Signal to noise for inspiral, merger, and ringdown

We estimate the expected signal-to-noise ratios (SNRs) from the three phases (inspiral,merger,ringdown) of coalescing binary black holes (BBHs) for initial and advanced ground-based interferometers (LIGO/VIRGO) and for space-based interferometers (LISA). LIGO/VIRGO can do moderate SNR (a few tens), moderate accuracy studies of BBH coalescences in the mass range of a few to about 2000 solar masses; LISA can do high SNR (of order 10^4) high accuracy studies in the mass range of about 10^5 to 10^8 solar masses. BBHs might well be the first sources detected by LIGO/VIRGO: they are visible to much larger distances (up to 500 Mpc by initial interferometers) than coalescing neutron star binaries (heretofore regarded as the "bread and butter" workhorse source for LIGO/VIRGO, visible to about 30 Mpc by initial interferometers). Low-mass BBHs (up to 50 solar masses for initial LIGO interferometers; 100 for advanced; 10^6 for LISA) are best searched for via their well-understood inspiral waves; higher mass BBHs must be searched for via their poorly understood merger waves and/or their well-understood ringdown waves. A matched filtering search for massive BBHs based on ringdown waves should be capable of finding BBHs in the mass range of about 100 to 700 solar masses out to 200 Mpc (initial LIGO interferometers), and 200 to 3000 solar masses out to about z=1 (advanced interferometers). The required number of templates is of order 6000 or less. Searches based on merger waves could increase the number of detected massive BBHs by a factor of order 10 or more over those found from inspiral and ringdown waves, without detailed knowledge of the waveform shapes, using a "noise monitoring" search algorithm. A full set of merger templates from numerical relativity could further increase the number of detected BBHs by an additional factor of up to 4.Comment: 40 pages, Revtex, psfig.tex, seven figures, submitted to Phys Rev