518 research outputs found
Locally erasable couplers for optical device testing in silicon on insulator
Wafer scale testing is critical to reducing production costs and increasing production yield. Here we report a method that allows testing of individual optical components within a complex optical integrated circuit. The method is based on diffractive grating couplers, fabricated using lattice damage induced by ion implantation of germanium. These gratings can be erased via localised laser annealing, which is shown to reduce the outcoupling efficiency by over 20 dB after the device testing is completed. Laser annealing was achieved by employing a CW laser, operating at visible wavelengths thus reducing equipment costs and allowing annealing through thick oxide claddings. The process used also retains CMOS compatibility
Imprints of the Quantum World in Classical Mechanics
The imprints left by quantum mechanics in classical (Hamiltonian) mechanics
are much more numerous than is usually believed. We show Using no physical
hypotheses) that the Schroedinger equation for a nonrelativistic system of
spinless particles is a classical equation which is equivalent to Hamilton's
equations.Comment: Paper submitted to Foundations of Physic
The 3D Structure of N132D in the LMC: A Late-Stage Young Supernova Remnant
We have used the Wide Field Spectrograph (WiFeS) on the 2.3m telescope at
Siding Spring Observatory to map the [O III] 5007{\AA} dynamics of the young
oxygen-rich supernova remnant N132D in the Large Magellanic Cloud. From the
resultant data cube, we have been able to reconstruct the full 3D structure of
the system of [O III] filaments. The majority of the ejecta form a ring of
~12pc in diameter inclined at an angle of 25 degrees to the line of sight. We
conclude that SNR N132D is approaching the end of the reverse shock phase
before entering the fully thermalized Sedov phase of evolution. We speculate
that the ring of oxygen-rich material comes from ejecta in the equatorial plane
of a bipolar explosion, and that the overall shape of the SNR is strongly
influenced by the pre-supernova mass loss from the progenitor star. We find
tantalizing evidence of a polar jet associated with a very fast oxygen-rich
knot, and clear evidence that the central star has interacted with one or more
dense clouds in the surrounding ISM.Comment: Accepted for Publication in Astrophysics & Space Science, 18pp, 8
figure
Explicit solution of the (quantum) elliptic Calogero-Sutherland model
We derive explicit formulas for the eigenfunctions and eigenvalues of the
elliptic Calogero-Sutherland model as infinite series, to all orders and for
arbitrary particle numbers and coupling parameters. The eigenfunctions obtained
provide an elliptic deformation of the Jack polynomials. We prove in certain
special cases that these series have a finite radius of convergence in the nome
of the elliptic functions, including the two particle (= Lam\'e) case for
non-integer coupling parameters.Comment: v1: 17 pages. The solution is given as series in q but only to low
order. v2: 30 pages. Results significantly extended. v3: 35 pages. Paper
completely revised: the results of v1 and v2 are extended to all order
Theory of Current and Shot Noise Spectroscopy in Single-Molecular Quantum Dots with Phonon Mode
Using the Keldysh nonequilibrium Green function technique, we study the
current and shot noise spectroscopy of a single molecular quantum dot coupled
to a local phonon mode. It is found that in the presence of electron-phonon
coupling, in addition to the resonant peak associated with the single level of
the dot, satellite peaks with the separation set by the frequency of phonon
mode appear in the differential conductance. In the ``single level'' resonant
tunneling region, the differential shot noise power exhibit two split peaks.
However, only single peaks show up in the ``phonon assisted''
resonant-tunneling region. An experimental setup to test these predictions is
also proposed.Comment: 5 pages, 3 eps figures embedde
The effects of cold working on sensitization and intergranular corrosion behavior of AISI 304 stainless steel
The effects of prior cold rolling of up to an 80 pct reduction in thickness on the sensitization-desensitization behavior of Type AISI 304 stainless steel and its susceptibility to intergranular corrosion have been studied by electrochemical potentiokinetic reactivation (EPR) and Strauss-test methods. The results indicate that the prior deformation accelerated the sensitization as compared to the undeformed stainless steel. The deformed Type 304 stainless steel experienced desensitization at higher temperatures and times, and it was found to be enhanced by increased cold deformation. This could be attributed to the increased long-range chromium diffusion, possibly brought on by increasing pipe diffusion and vacancies. The role of the deformation-induced martensite (DIM) and texture, introduced by uniaxial cold rolling, on the sensitization-desensitization kinetics has also been discussed. This study could not reveal any systematic relationship between texture and the degree of sensitization (DOS) obtained. The effect of DIM on DOS seems to be pronounced at 500 °C when the steel retained significant amounts of DIM; however, the retained DIM is insignificant at higher sensitization times and temperatures
L-selectin enhanced T cells improve the efficacy of cancer immunotherapy
The T cell homing molecule, L-selectin (CD62L), is commonly used as a marker of T cell activation, as expression of L-selectin is downregulated following engagement of the T cell receptor. Furthermore, it is used to distinguish “central memory” T cells (TCM) from, “effector memory” T cells (TEM). It has been reported that CD8+ T cells with a CD62L+ TCM phenotype are better able to control tumour growth than CD62L- TEM CD8+ T cells, while L-selectin knockout T cells are poor at controlling tumour growth. Here, we test the hypothesis that T cells expressing a genetically modified form of L-selectin that is not downregulated following T cell activation (L-selectin enhanced T cells) are better able to control tumour growth than wild type T cells. Using mouse models of solid and disseminated tumours, we show that L-selectin enhancement improves the efficacy of CD8+ T cells in controlling tumour growth. Longitudinal tracking of Zirconium-89 (89Zr) labelled T cells using PET-CT showed that transferred T cells localised to tumours within 24 hours. Early T cell recruitment into tumours was not dependent on L-selectin, however, upregulation of the early activation marker CD69 was higher on L-selectin expressing T cells both inside tumours and in secondary lymphoid organs. Reduced growth of tumours by L-selectin enhanced T cells correlated with increased frequency of CD8+ tumour infiltrating T cells 21 days after commencing therapy. Ex vivo analysis showed that clonal expansion of L-selectin enhanced T cells was slower, and that L-selectin was linked to expression of the proliferation marker Ki67. Together these findings indicate that maintaining L-selectin expression on tumour-specific T cells offers an advantage in mouse models of cancer immunotherapy. The beneficial role of L-selectin may be unrelated to its’ well-known role in T cell homing and instead linked to activation, clonal expansion and retention of therapeutic T cells. These findings have implications both for the selection of T cell subsets for adoptive transfer immunotherapy, and for possible modifications of transgenic chimeric antigen receptor (CAR) T cells to broaden the clinical scope of these therapies
Horizontal Branch Stars: The Interplay between Observations and Theory, and Insights into the Formation of the Galaxy
We review HB stars in a broad astrophysical context, including both variable
and non-variable stars. A reassessment of the Oosterhoff dichotomy is
presented, which provides unprecedented detail regarding its origin and
systematics. We show that the Oosterhoff dichotomy and the distribution of
globular clusters (GCs) in the HB morphology-metallicity plane both exclude,
with high statistical significance, the possibility that the Galactic halo may
have formed from the accretion of dwarf galaxies resembling present-day Milky
Way satellites such as Fornax, Sagittarius, and the LMC. A rediscussion of the
second-parameter problem is presented. A technique is proposed to estimate the
HB types of extragalactic GCs on the basis of integrated far-UV photometry. The
relationship between the absolute V magnitude of the HB at the RR Lyrae level
and metallicity, as obtained on the basis of trigonometric parallax
measurements for the star RR Lyrae, is also revisited, giving a distance
modulus to the LMC of (m-M)_0 = 18.44+/-0.11. RR Lyrae period change rates are
studied. Finally, the conductive opacities used in evolutionary calculations of
low-mass stars are investigated. [ABRIDGED]Comment: 56 pages, 22 figures. Invited review, to appear in Astrophysics and
Space Scienc
Single Spin Asymmetry in Polarized Proton-Proton Elastic Scattering at GeV
We report a high precision measurement of the transverse single spin
asymmetry at the center of mass energy GeV in elastic
proton-proton scattering by the STAR experiment at RHIC. The was measured
in the four-momentum transfer squared range \GeVcSq, the region of a significant interference between the
electromagnetic and hadronic scattering amplitudes. The measured values of
and its -dependence are consistent with a vanishing hadronic spin-flip
amplitude, thus providing strong constraints on the ratio of the single
spin-flip to the non-flip amplitudes. Since the hadronic amplitude is dominated
by the Pomeron amplitude at this , we conclude that this measurement
addresses the question about the presence of a hadronic spin flip due to the
Pomeron exchange in polarized proton-proton elastic scattering.Comment: 12 pages, 6 figure
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