Prameha and role of Pathya : A Review

Ahara is an inevitable part of life along with air and water. Food is anything that is consumed and nourishes body, including medicine. As mentioned by Acharya Kashyapa consuming food in appropriate quantity, following all the rules and regulation is considered to cure disease; further improper method of consumption of food is said manifest disease. It is also mentioned that the food is the life of the living beings and clear complexion, good voice, life, ability, happiness, nourishment, built, strength, intellect is all dependent on the food one consumes. Therefore, food is considered as one among Trayopasthamba. In Yogaratnakara, it is said that for the treatment of diseases etiology, drug treatment and Pathya (wholesome) are three important factors which should be studied thoroughly before starting the treatment. Judicious planning of treatment by proper understanding of these three factors always yields a successful eradication of disease. Prameha is considered as a type of Santarpanajanya Vikara. Charaka in Nidanasthana gives the detailed explanation of Nidana and other Samprapti Ghataka in detail. Prameha is frequently correlated with diabetes mellitus type 2 based on clinical manifestations. Pathya – Apathya plays supportive role in the management of Yapya Vyadhi especially like that of Prameha. Acharyas indicated the importance of Pathya Ahara by stating that if a patient take wholesome food then there is no need of medicine and if a patient continuously consumes unwholesome food then also there is no need of medicine

ADDING NEW RACKS AND RECABLING WITHOUT NETWORK DISRUPTION AND FACILITATING MIS-CABLING DETECTION

As network fabric deployments continue to grow larger and more immense, there are challenges involving the management cabling arrangements and debugging mis-cabling issues for large-scale full mesh leaf-spine networks. Additionally, the need for the automatic discovery of every component of a large fabric, which can be expanded dynamically, becomes a challenging task. Accordingly, techniques are presented herein that aid in the automatic detection of mis-cabling issues, the automatic discovery of a rack’s location within a large-scale data center, and the automatic detection of the addition of a new rack to a data center, all without disrupting network traffic within a dynamically expanding fabric. Aspects of the presented techniques provide an algorithm that can automatically detect such mis-cabling issues. Further aspects of the presented techniques support a tool that may be used to detect mis-cabling (e.g., in the case of inter-communication failures among the nodes)

A rare case of plasma cell osteomyelitis with atypical presentation

Plasma cell osteomyelitis is an uncommon type of localized chronic osteomyelitis which is characterized by the absence of typical clinical features of infection. It usually affects the metaphysis of long bones and presents as dense thickening of bone without sequestrum formation. We present an atypical case of plasma cell osteomyelitis with a lesion in the diaphysis of long bone and sequestrum formation. A 23 year old male patient came to our OPD with complaint of pain in mid-thigh radiating to the left knee since 2 months. X-ray showed radiolucencies in the medulla of middle third of shaft of femur along with a linear sequestrum suggestive of chronic osteomyelitis. An open biopsy was performed and surgical curettage was done. Histopathological examination was consistent with plasma cell osteomyelitis. Chronic plasma cell osteomyelitis is a rare condition with nonspecific findings and an unclear cause. Histopathology is the definitive tool for obtaining a diagnosis. Knowledge of this condition and proper management can give a better outcome, at the same time avoiding unnecessary investigations and procedures

Prevalence of gestational diabetes mellitus and perinatal outcome: a rural tertiary teaching hospital based study

Background: Gestational diabetes mellitus is the commonest medical disorder in pregnancy. Women with GDM are at increased risk for adverse obstetric and perinatal outcome. Prevalence of GDM is known to vary widely depending on region of the country, dietary habits and socio-economic status. This study was undertaken to evaluate the prevalence of GDM and risk factors associated with it among women delivered in a rural tertiary teaching hospital in Telangana and further assess its impact on feto-maternal outcome.Methods: A retrospective study was conducted at Mediciti Institute of Medical Sciences on GDM cases delivered from May 2015 to April 2017. GDM was diagnosed using 2 step procedure of screening with glucose challenge test followed by confirmation with oral glucose tolerance test using Carpenter and Couston criteria. Demographic data and details about perinatal outcome were obtained from medical records and analyzed.Results: The prevalence was low (1.83%) compared to other studies. Majority of the women did not have risk factors. Preeclampsia is the commonest maternal complication seen (18%). Hypothyroidism is more often associated with GDM (15%). Caesarean section rate was high (62%). Though the NICU admission rate was high (76%), neonatal outcome was found to be satisfactory.Conclusions: The low prevalence of GDM seen highlights the importance of carrying out studies in different population groups of India to know the exact prevalence of GDM in the country. Pregnancies in women with GDM continue to be at increased risk of maternal and perinatal complications

Sperm mitochondrial mutations as a cause of low sperm motility

We report the unique case of a 28-year-old man who, in spite of having a varicocele and a sperm concentration of 5 million/mL, of which 10% were motile and 20% had normal forms (oligoasthenoteratozoospermia [OAT]), was fertile. This was confirmed by paternity testing using 16 autosomal and 6 Y-chromosomal short tandem repeat (STR) loci. An analysis of mitochondrial genes that included cytochrome oxidase I (COI), cytochrome oxidase II (COII), adenosine triphosphate synthase6 (ATPase6), ATPase8, transfer ribonucleic acid (tRNA) serine I, tRNA lysine, and NADH dehydrogenase3 (ND3) revealed, for the first time, 9 missense and 27 silent mutations in the sperm's mitochondrial DNA (mtDNA) but not in the DNA from the blood cells. There was a 2-nucleotide deletion in the mitochondrial COII genes, introducing a stop codon, which might be responsible for low sperm motility

ROLE OF DRIP IRRIGATION IN PLANT HEALTH MANAGEMENT, ITS IMPORTANCE AND MAINTENANCE

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Anthracnose of Capsicum annuum L. (Chilli)

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