343 research outputs found
KINEMATIC AND KINETIC PATTERNS IN OLYMPIC WEIGHTLIFTING
The purpose of this study was to identify lower extremity kinematic and kinetic patterns during weightlifting movements and to compare them across different external loads. Subjects completed multiple sets of the clean exercise at various percentage loads. Principal component analysis (PCA) was used to extract kinematic and kinetics patterns of the hip, knee, and ankle joint across the loads. These patterns were then compared across joint and percentage load. Results indicate that lower extremity kinematics and kinetics can be characterized through combinations of PCA-derived patterns. Patterns differed predominantly between joints, but not across percentage loads. The results point to joint-specific lower extremity function during Olympic weightlifting and quantified important technical aspects
Crecimiento en función de la densidad de poliquetos Diopatra aciculata
Effects of intraspecific density on growth of the tube-building polychaete Diopatra aciculata (Onuphidae) were examined over a three-month period within a marine worm aquaculture facility. Three polychaete densities (500, 1000 and 2000 worms/m2) were represented within triplicate 0.30 m2 boxes containing late juvenile D. aciculata, sandy sediment and recirculating seawater. Daily food ration per worm was held constant across all density levels. Total length, weight and number of segments were recorded for 20 polychaetes randomly removed from each of nine treatment boxes at weeks 1, 7 and 14. Mean daily growth was higher during weeks 1-7 than during weeks 7-14 for all growth variables at each density level. Polychaetes at the highest density level exhibited lower rates of growth and more broken and/or regenerating posterior segments than those at low density. High D. aciculata density was also associated with reduced dissolved oxygen concentrations and high polychaete mortality (20%). At medium polychaete density (1000/m2), D. aciculata exhibited low levels of apparent stress and high biomass return per unit area, both of which are important considerations in the aquaculture rearing of this species. We suggest that further studies focus on age- and size-related factors contributing to density effects on polychaete growth.Durante un período de más de tres meses se examinaron en instalaciones de acuicultura de gusanos marinos los efectos de la densidad interespecífica en el crecimiento del poliqueto tubícola Diopatra aciculata (Onuphidae). Se utilizaron tres niveles de densidad de poliquetos (aproximadamente 500, 1000 y 2000 gusanos/m2) en cajas experimentales de 0,30 m2 replicadas, conteniendo ejemplares juveniles avanzados de D. aciculata y sedimento arenoso, todo ello con recirculación de agua marina. La ración diaria de alimento por gusano se mantuvo constante en todos los niveles de densidad. Se registró la longitud total, el peso, y el número de segmentos en 20 poliquetos extraídos aleatoriamente para cada tratamiento durante las semanas 1, 7, y 14. Para cada uno de los niveles de densidad estudiados, el crecimiento diario promedio durante el período entre la semana 1 y la 7 fue mayor que durante el período entre la semana 7 y la 14 en todas las variables de crecimiento. Los poliquetos cultivados a mayores densidades poblacionales exhibieron menores tasas de crecimiento y un mayor número de segmentos posteriores fragmentados y/o regenerados que aquellos cultivados a menores densidades de población. Asimismo, la alta densidad de D. aciculata provocó menores concentraciones de oxígeno disuelto y un mayor índice de mortalidad de poliquetos (20% promedio). Al nivel medio de densidad de poliquetos (1000/m2), los ejemplares de D. aciculata presentaron un bajo nivel de estrés aparente y una elevada producción de biomasa por unidad de área, dos factores importantes en la crianza mediante técnicas de acuicultura de esta especie. Para posteriores estudios, se propone concentrarse en los efectos de la densidad en el comportamiento interactivo y en la competencia por el alimento.  
Predictors of Comorbid Eating Disorders and Association with Other Obsessive-Compulsive Spectrum Disorders in Trichotillomania
Trichotillomania (TTM) and eating disorders (ED) share many phenomenological similarities, including ritualized compulsive behaviors. Given this, and that comorbid EDs may represent additional functional burden to hair pullers, we sought to identify factors that predict diagnosis of an ED in a TTM population. Subjects included 555 adult females (age range 18–65) with DSM-IV-TR TTM or chronic hair pullers recruited from multiple sites. 7.2% (N = 40) of our TTM subjects met criteria for an ED in their lifetime. In univariable regression analysis, obsessive-compulsive disorder (OCD), Yale-Brown Obsessive Compulsive Scale (Y-BOCS) worst-ever compulsion and total scores, certain obsessive-compulsive spectrum disorders, anxiety disorder, attention-deficit/hyperactivity disorder (ADHD), and substance disorder all met the pre-specified criteria for inclusion in the multivariable analysis. In the final multivariable model, diagnosis of OCD (OR: 5.68, 95% CI: 2.2–15.0) and diagnosis of an additional body-focused repetitive behavior disorder (BFRB) (OR: 2.69, 95% CI: 1.1–6.8) were both associated with increased risk of ED in TTM. Overall, our results provide further support of the relatedness between ED and TTM. This finding highlights the importance of assessing for comorbid OCD and additional BFRBs in those with TTM. Future research is needed to identify additional predictors of comorbid disorders and to better understand the complex relationships between BFRBs, OCD and EDs
Fc receptor-like 2 (FCRL2) is a novel marker of low-risk CLL and refines prognostication based on IGHV mutation status
Improved Water and Nutrient Management Through HighFrequency Irrigation
High frequency irrigation implies the uniform, frequent application of water to crops. The fequency may range from several irrigations per week to daily irrigation to even several irrigations per day in greenhouse and nursery settings. Most of the high frequency irrigation in the United States is through necessity; i.e., the limited water holding capacity of the soils or a limited water supply make irrigation application of more than a few centimeters impractical.
Irrigation of field crops in sandy soils (such as in the Nebraska Sand Hills) with traveling or outer pivot sprinkler systems is a classic example of high frequency irrigation dictated by a limited water holding capacity. Another widespread use of high frequency irrigation is found in the various low pressure systems such as drip, trickle, bi-well, and bubbler. These systems deliver relatively small amounts of water to the root zone as a consequence of factors such as limited water, shallow soils, limited water holding capacity, and high erosion potential.
The increased frequency of irrigation is not commonly a goal in itself, but several advantages of high frequency irrigation have been identified (Rawlins and Raats, 1975; Howell, et. al., 1976). These include:
1. Improved plant internal water balance,
2. Decreased drainage from the root zone,
3. Decreased runoff from the crop,
4. Decreased importance of soil hydraulic characteristics,
5. Improved salinity control,
6. Increased enhancement of rainfall utilization,
7. Reduction of high temperature stress, and
8. Reduction of nutrient leaching
The results of these advantages are usually increased crop yield or quality, decreased water use, and decreased pollution from drainage and runoff. The yield expected under high frequency irrigation may not be signsficantly increased over well-managed conventional irrigation, but increased efficiency of water, energy, fertilizer, and labor make even modest yield increases important.
Nutrient management is critical with high frequency irrigation. Nitrogen in particular is susceptible to loss from the root zone by leaching, so high frequency irrigation systems require frequent, light nitrogen applications. This is facilitated by distribution of nutrients through the irrigation system. Other chemicals such as soil fumigents for nematode control, systemic insecticides, and herbicides can also be injected into the irrigation system and applied very uniformly to the crop.
This research was directed toward defining the best management practices for irrigation timing and fertilizer applications under high frequency irrigation. The specific objectives were to:
1. quantitatively determine plant nutrient requirements for specific crops grown under high frequency irrigation, under optimum soil-water metric potential, and
2. evaluate the impact of high frequency irrigation on water quality and water and energy consumption
Association Analysis in African Americans of European-Derived Type 2 Diabetes Single Nucleotide Polymorphisms From Whole-Genome Association Studies
OBJECTIVE— Several whole-genome association studies have reported identification of type 2 diabetes susceptibility genes in various European-derived study populations. Little investigation of these loci has been reported in other ethnic groups, specifically African Americans. Striking differences exist between these populations, suggesting they may not share identical genetic risk factors. Our objective was to examine the influence of type 2 diabetes genes identified in whole-genome association studies in a large African American case-control population
Comparing self-reported ethnicity to genetic background measures in the context of the Multi-Ethnic Study of Atherosclerosis (MESA)
<p>Abstract</p> <p>Background</p> <p>Questions remain regarding the utility of self-reported ethnicity (SRE) in genetic and epidemiologic research. It is not clear whether conditioning on SRE provides adequate protection from inflated type I error rates due to population stratification and admixture. We address this question using data obtained from the Multi-Ethnic Study of Atherosclerosis (MESA), which enrolled individuals from 4 self-reported ethnic groups. We compare the agreement between SRE and genetic based measures of ancestry (GBMA), and conduct simulation studies based on observed MESA data to evaluate the performance of each measure under various conditions.</p> <p>Results</p> <p>Four clusters are identified using 96 ancestry informative markers. Three of these clusters are well delineated, but 30% of the self-reported Hispanic-Americans are misclassified. We also found that MESA SRE provides type I error rates that are consistent with the nominal levels. More extensive simulations revealed that this finding is likely due to the multi-ethnic nature of the MESA. Finally, we describe situations where SRE may perform as well as a GBMA in controlling the effect of population stratification and admixture in association tests.</p> <p>Conclusions</p> <p>The performance of SRE as a control variable in genetic association tests is more nuanced than previously thought, and may have more value than it is currently credited with, especially when smaller replication studies are being considered in multi-ethnic samples.</p
Approaching public perceptions of datafication through the lens of inequality: a case study in public service media
In the emerging field of critical data studies, there is increasing acknowledgement that the negative effects of datafication are not experienced equally by all. Research on data and discrimination in particular has highlighted how already socially unequal populations are discriminated against in data-driven systems. Elsewhere, there is growing interest in public perceptions of datafication, amongst academic researchers interested in producing ‘bottom up’ understandings of the new roles of data in society and non-academic stakeholders keen to
establish positive perceptions of data-driven systems. However, research into public perceptions rarely engages with the issue of inequality which is so central in data and discrimination
scholarship. Bringing these two issues together, this paper explores public perceptions of datafication through the lens of inequality, focusing on the relationship between understandings
and feelings within these perceptions. The paper draws on empirical focus group research into how audiences perceive the data practices that signing in to access BBC digital services enable. The paper shows how inequalities relating to age, dis/ability, poverty and their intersections played a role in shaping perceptions and that these social inequalities informed understandings of and feelings about data practices in complex and diverse ways. It concludes with reflections on the significance of these findings for future research and for data-related policy
Intervention planning and modification of the BUMP intervention: a digital intervention for the early detection of raised blood pressure in pregnancy
Background: Hypertensive disorders in pregnancy, particularly pre-eclampsia, pose a substantial health risk for both maternal and foetal outcomes. The BUMP (Blood Pressure Self-Monitoring in Pregnancy) interventions are being tested in a trial. They aim to facilitate the early detection of raised blood pressure through self-monitoring. This article outlines how the self-monitoring interventions in the BUMP trial were developed and modified using the person-based approach to promote engagement and adherence.
Methods: Key behavioural challenges associated with blood pressure self-monitoring in pregnancy were identified through synthesising qualitative pilot data and existing evidence, which informed guiding principles for the development process. Social cognitive theory was identified as an appropriate theoretical framework. A testable logic model was developed to illustrate the hypothesised processes of change associated with the intervention. Iterative qualitative feedback from women and staff informed modifications to the participant materials.
Results: The evidence synthesis suggested women face challenges integrating self-monitoring into their lives and that adherence is challenging at certain time points in pregnancy (for example, starting maternity leave). Intervention modification included strategies to address adherence but also focussed on modifying outcome expectancies, by providing messages explaining pre-eclampsia and outlining the potential benefits of self-monitoring.
Conclusions: With an in-depth understanding of the target population, several methods and approaches to plan and develop interventions specifically relevant to pregnant women were successfully integrated, to address barriers to behaviour change while ensuring they are easy to engage with, persuasive and acceptable
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