20 research outputs found

    OSO head and tape studies Final report

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    OSO recording head and tape studie

    Non-coding RNAs and disease: the classical ncRNAs make a comeback

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    Abstract Many human diseases have been attributed to mutation in the protein coding regions of the human genome. The protein coding portion of the human genome, however, is very small compared with the non-coding portion of the genome. As such, there are a disproportionate number of diseases attributed to the coding compared with the non-coding portion of the genome. It is now clear that the non-coding portion of the genome produces many functional non-coding RNAs and these RNAs are slowly being linked to human diseases. Here we discuss examples where mutation in classical non-coding RNAs have been attributed to human disease and identify the future potential for the non-coding portion of the genome in disease biology

    Performance enhancement solutions in wireless communication networks

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    In this dissertation thesis, we study the new relaying protocols for different wireless network systems. We analyze and evaluate an efficiency of the transmission in terms of the outage probability over Rayleigh fading channels by mathematical analyses. The theoretical analyses are verified by performing Monte Carlo simulations. First, we study the cooperative relaying in the Two-Way Decode-and-Forward (DF) and multi-relay DF scheme for a secondary system to obtain spectrum access along with a primary system. In particular, we proposed the Two-Way DF scheme with Energy Harvesting, and the Two-Way DF Non-orthogonal Multiple Access (NOMA) scheme with digital network coding. Besides, we also investigate the wireless systems with multi-relay; the best relay selection is presented to optimize the effect of the proposed scheme. The transmission protocols of the proposed schemes EHAF (Energy Harvesting Amplify and Forward) and EHDF (Energy Harvesting Decode and Forward) are compared together in the same environment and in term of outage probability. Hence, with the obtained results, we conclude that the proposed schemes improve the performance of the wireless cooperative relaying systems, particularly their throughput. Second, we focus on investigating the NOMA technology and proposing the optimal solutions (protocols) to advance the data rate and to ensure the Quality of Service (QoS) for the users in the next generation of wireless communications. In this thesis, we propose a Two-Way DF NOMA scheme (called a TWNOMA protocol) in which an intermediate relay helps two source nodes to communicate with each other. Simulation and analysis results show that the proposed protocol TWNOMA is improving the data rate when comparing with a conventional Two-Way scheme using digital network coding (DNC) (called a TWDNC protocol), Two-Way scheme without using DNC (called a TWNDNC protocol) and Two-Way scheme in amplify-and-forward(AF) relay systems (called a TWANC protocol). Finally, we considered the combination of the NOMA and physical layer security (PLS) in the Underlay Cooperative Cognitive Network (UCCN). The best relay selection strategy is investigated, which uses the NOMA and considers the PLS to enhance the transmission efficiency and secrecy of the new generation wireless networks.V této dizertační práci je provedena studie nových přenosových protokolů pro různé bezdrátové síťové systémy. S využitím matematické analýzy jsme analyzovali a vyhodnotili efektivitu přenosu z hlediska pravděpodobnosti výpadku přes Rayleighův kanál. Teoretické analýzy jsou ověřeny provedenými simulacemi metodou Monte Carlo. Nejprve došlo ke studii kooperativního přenosu ve dvoucestném dekóduj-a-předej (Two-Way Decode-and-Forward–TWDF) a vícecestném DF schématu s větším počtem přenosových uzlů pro sekundární systém, kdy takto byl získán přístup ke spektru spolu s primárním systémem. Konkrétně jsme navrhli dvoucestné DF schéma se získáváním energie a dvoucestné DF neortogonální schéma s mnohonásobným přístupem (Non-orthogonal Multiple Access–NOMA) s digitálním síťovým kódováním. Kromě toho rovněž zkoumáme bezdrátové systémy s větším počtem přenosových uzlů, kde je přítomen výběr nejlepšího přenosového uzlu pro optimalizaci efektivnosti navrženého schématu. Přenosové protokoly navržených schémat EHAF (Energy Harvesting Amplify and Forward) a EHDF(Energy Harvesting Decode and Forward) jsou společně porovnány v identickém prostředí z pohledu pravděpodobnosti výpadku. Následně, na základě získaných výsledků, jsme dospěli k závěru, že navržená schémata vylepšují výkonnost bezdrátových kooperativních systémů, konkrétně jejich propustnost. Dále jsme se zaměřili na zkoumání NOMA technologie a navrhli optimální řešení (protokoly) pro urychlení datového přenosu a zajištění QoS v další generaci bezdrátových komunikací. V této práci jsme navrhli dvoucestné DF NOMA schéma (nazýváno jako TWNOMA protokol), ve kterém mezilehlý přenosový uzel napomáhá dvěma zdrojovým uzlům komunikovat mezi sebou. Výsledky simulace a analýzy ukazují, že navržený protokol TWNOMA vylepšuje dosaženou přenosovou rychlost v porovnání s konvenčním dvoucestným schématem používajícím DNC (TWDNC protokol), dvoucestným schématem bez použití DNC (TWNDNC protokol) a dvoucestným schématem v zesil-a-předej (amplify-and-forward) přenosových systémech (TWANC protokol). Nakonec jsme zvážili využití kombinace NOMA a zabezpečení fyzické vrstvy (Physical Layer Security–PLS) v podpůrné kooperativní kognitivní síti (Underlay Cooperative Cognitive Network–UCCN). Zde je zde zkoumán výběr nejlepšího přenosového uzlu, který užívá NOMA a bere v úvahu PLS pro efektivnější přenos a zabezpečení nové generace bezdrátových sítí.440 - Katedra telekomunikační technikyvyhově

    Notes on Contributors

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    Notes on Contributors

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    Normal table of Xenopus development: a new graphical resource

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    © The Author(s), 2022. This article is distributed under the terms of the Creative Commons Attribution License. The definitive version was published in Zahn, N., James-Zorn, C., Ponferrada, V. G., Adams, D. S., Grzymkowski, J., Buchholz, D. R., Nascone-Yoder, N. M., Horb, M., Moody, S. A., Vize, P. D., & Zorn, A. M. Normal table of Xenopus development: a new graphical resource. Development, 149(14), (2022): dev200356, https://doi.org/10.1242/dev.200356.Normal tables of development are essential for studies of embryogenesis, serving as an important resource for model organisms, including the frog Xenopus laevis. Xenopus has long been used to study developmental and cell biology, and is an increasingly important model for human birth defects and disease, genomics, proteomics and toxicology. Scientists utilize Nieuwkoop and Faber's classic ‘Normal Table of Xenopus laevis (Daudin)’ and accompanying illustrations to enable experimental reproducibility and reuse the illustrations in new publications and teaching. However, it is no longer possible to obtain permission for these copyrighted illustrations. We present 133 new, high-quality illustrations of X. laevis development from fertilization to metamorphosis, with additional views that were not available in the original collection. All the images are available on Xenbase, the Xenopus knowledgebase (http://www.xenbase.org/entry/zahn.do), for download and reuse under an attributable, non-commercial creative commons license. Additionally, we have compiled a ‘Landmarks Table’ of key morphological features and marker gene expression that can be used to distinguish stages quickly and reliably (https://www.xenbase.org/entry/landmarks-table.do). This new open-access resource will facilitate Xenopus research and teaching in the decades to come.This work was supported by grants from the Eunice Kennedy Shriver National Institute of Child Health and Human Development [P41 HD064556 to A.M.Z. and P.D.V. (Xenbase)] and the National Institute of Child Health and Human Development [P40-OD010997 and R24-OD030008 to M.H. (National Xenopus Resource)]. Open Access funding provided by Cincinnati Children's Hospital Medical Center. Deposited in PMC for immediate release

    January 5, 1967

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    https://scholarlycommons.obu.edu/arbn_65-69/1096/thumbnail.jp

    Relaying in the Internet of Things (IoT): A Survey

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    The deployment of relays between Internet of Things (IoT) end devices and gateways can improve link quality. In cellular-based IoT, relays have the potential to reduce base station overload. The energy expended in single-hop long-range communication can be reduced if relays listen to transmissions of end devices and forward these observations to gateways. However, incorporating relays into IoT networks faces some challenges. IoT end devices are designed primarily for uplink communication of small-sized observations toward the network; hence, opportunistically using end devices as relays needs a redesign of both the medium access control (MAC) layer protocol of such end devices and possible addition of new communication interfaces. Additionally, the wake-up time of IoT end devices needs to be synchronized with that of the relays. For cellular-based IoT, the possibility of using infrastructure relays exists, and noncellular IoT networks can leverage the presence of mobile devices for relaying, for example, in remote healthcare. However, the latter presents problems of incentivizing relay participation and managing the mobility of relays. Furthermore, although relays can increase the lifetime of IoT networks, deploying relays implies the need for additional batteries to power them. This can erode the energy efficiency gain that relays offer. Therefore, designing relay-assisted IoT networks that provide acceptable trade-offs is key, and this goes beyond adding an extra transmit RF chain to a relay-enabled IoT end device. There has been increasing research interest in IoT relaying, as demonstrated in the available literature. Works that consider these issues are surveyed in this paper to provide insight into the state of the art, provide design insights for network designers and motivate future research directions

    The Cowl - v.27 - n.8 - Mar 27, 1974

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    The Cowl - student newspaper of Providence College. Volume 27, Number 8 - March 27, 1974. 16 pages. Note: The volume number printed on the banner page of this issue (XXVII) duplicates the volume number for 1964-65 academic year

    Phillips Phonograph : Vol 4. No. 32 April 15, 1882

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    https://digitalmaine.com/phillips_phonograph/1285/thumbnail.jp
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