Critical speeds and forced response solutions for active magnetic bearing turbomachinery, part 2

The need for better performance of turbomachinery with active magnetic bearings has necessitated a study of such systems for accurate prediction of their vibrational characteristics. A modification of existing transfer matrix methods for rotor analysis is presented to predict the response of rotor systems with active magnetic bearings. The position of the magnetic bearing sensors is taken into account and the effect of changing sensor position on the vibrational characteristics of the rotor system is studied. The modified algorithm is validated using a simpler Jeffcott model described previously. The effect of changing from a rotating unbalance excitation to a constant excitation in a single plane is also studied. A typical eight stage centrifugal compressor rotor is analyzed using the modified transfer matrix code. The results for a two mass Jeffcott model were presented previously. The results obtained by running this model with the transfer matrix method were compared with the results of the Jeffcott analysis for the purposes of verification. Also included are plots of amplitude versus frequency for the eight stage centrifugal compressor rotor. These plots demonstrate the significant influence that sensor location has on the amplitude and critical frequencies of the rotor system

Cycloidal-drive joint design for wearable exoskeletons

This thesis\u27s scope was to construct a highly back drivable and compact joint design that can be used for wearable exoskeletons specifically designed to assist with rehabilitation. A compact cycloidal gear transmission was designed to satisfy the compactness requirement while ensuring the minimum torque is required for backdriving the mechanism. The joint was designed based on the compact cycloidal drive specifications, and the backdrivability test was performed to measure the minimum torque required (1.20 Nm) to backdrive. The joint design incorporates various important features such as rotation lock feature to prevent hyperextension, a housing design that offers the benefit of using the joint for the left and right limb, a motor mount that securely holds a brushless DC motor, and a sensor bracket that securely positions a control sensor over the motor for controlling the motor position and speed. Successful evaluation of the 3D printed prototype validated the integrity of the design

A sense of embodiment is reflected in people's signature size

BACKGROUND: The size of a person's signature may reveal implicit information about how the self is perceived although this has not been closely examined. METHODS/RESULTS: We conducted three experiments to test whether increases in signature size can be induced. Specifically, the aim of these experiments was to test whether changes in signature size reflect a person's current implicit sense of embodiment. Experiment 1 showed that an implicit affect task (positive subliminal evaluative conditioning) led to increases in signature size relative to an affectively neutral task, showing that implicit affective cues alter signature size. Experiments 2 and 3 demonstrated increases in signature size following experiential self-focus on sensory and affective stimuli relative to both conceptual self-focus and external (non-self-focus) in both healthy participants and patients with anorexia nervosa, a disorder associated with self-evaluation and a sense of disembodiment. In all three experiments, increases in signature size were unrelated to changes in self-reported mood and larger than manipulation unrelated variations. CONCLUSIONS: Together, these findings suggest that a person's sense of embodiment is reflected in their signature size

Bacteriological Status Of Meat During Various Stages Of Processing In AFD Packing Plant

Studies on eight carcasses(sheep/goat) for microbial status of meat at different stages of processing viz dressed carcass before after chilling, after boning, cocking, cooking, cooling, slicing, deep freezing, freeze drying, and packing have been carried out. No difference in microbial status has been observed in sheep and goat carcass. The lower (front body) portion of carcass has higher microbial load than the upper portion (hind body). No significant increase in total colony counts was observed on keeping the carcass for 24 hours at 5 degree centigrade. The highest microbial load has been observed on boned meat. The total colony counts (TCC) gets reduced during the process of deep freezing and freeze drying. The precooked, freeze dried meat has TCC up to 266

Extrinsic and intrinsic preanalytical variables affecting liquid biopsy in cancer

Liquid biopsy, through isolation and analysis of disease-specific analytes, has evolved as a promising tool for safe and minimally invasive diagnosis and monitoring of tumors. It also has tremendous utility as a companion diagnostic allowing detection of biomarkers in a range of cancers (lung, breast, colon, ovarian, brain). However, clinical implementation and validation remains a challenge. Among other stages of development, preanalytical variables are critical in influencing the downstream cellular and molecular analysis of different analytes. Although considerable progress has been made to address these challenges, a comprehensive assessment of the impact on diagnostic parameters and consensus on standardized and optimized protocols is still lacking. Here, we summarize and critically evaluate key variables in the preanalytical stage, including study population selection, choice of biofluid, sample handling and collection, processing, and storage. There is an unmet need to develop and implement comprehensive preanalytical guidelines on the optimal practices and methodologies

The Liquid Biopsy Consortium: Challenges and opportunities for early cancer detection and monitoring

The emerging field of liquid biopsy stands at the forefront of novel diagnostic strategies for cancer and other diseases. Liquid biopsy allows minimally invasive molecular characterization of cancers for diagnosis, patient stratification to therapy, and longitudinal monitoring. Liquid biopsy strategies include detection and monitoring of circulating tumor cells, cell-free DNA, and extracellular vesicles. In this review, we address the current understanding and the role of existing liquid-biopsy-based modalities in cancer diagnostics and monitoring. We specifically focus on the technical and clinical challenges associated with liquid biopsy and biomarker development being addressed by the Liquid Biopsy Consortium, established through the National Cancer Institute. The Liquid Biopsy Consortium has developed new methods/assays and validated existing methods/technologies to capture and characterize tumor-derived circulating cargo, as well as addressed existing challenges and provided recommendations for advancing biomarker assays

Wheat Yield Trend and Soil Fertility Status in Long Term Rice-Rice-Wheat Cropping System

A long-term soil fertility experiment under rice-rice-wheat system was performed to evaluate the long term effects of inorganic fertilizer and manure applications on soil properties and grain yield of wheat. The experiment began since 1978 was laid out in randomized complete block design with 9 treatments replicated 3 times. From 1990 onwards, periodic modifications have been made in all the treatments splitting the plots in two equal halves of 4 x 3 m2 leaving one half as original. In the original treatments, recent data revealed that the use of Farm Yard Manure (FYM) @10 t ha-1 gave significantly (P≤0.05) higher yield of 2.3 t ha-1 in wheat, whereas control plot gave the lowest grain yield of 277 kg ha-1. Similarly, in the modified treatments, the use of FYM @10 t ha-1 along with inorganic Nitrogen (N) and Potassium oxide (K2O) @ 50 kg ha-1 produced significantly (P≤0.05) the highest yield of 2.4 t/ha in wheat. The control plot with an indigenous nutrient supply only produced wheat yield of 277 kg ha-1 after 35th year completion of rice-rice-wheat system. A sharp decline in wheat yields was noted in minus N, phosphorus (P), Potassium (K) treatments during recent years. Yields were consistently higher in the N:P2O5:K2O and FYM treatments than in treatments, where one or more nutrients were lacking. The application of P2O5 and K2O caused a partial recovery of yield in P and K deficient plots. There was significant (P≤0.05) effect of use of chemical fertilizers and manure on soil properties. The soil analysis data showed an improvement in soil pH (7.8), soil organic matter (4.1%), total N content (0.16%), available P (503.5 kg P2O5 ha-1) and exchangeable K (137.5 kg K2O ha-1) in FYM applied treatments over all other treatments. The findings showed that the productivity of the wheat can be increased and sustained by improving nutrient through the integrated use of organic and inorganic manures in long term.Journal of Nepal Agricultural Research Council Vol.1 2015 pp.21-2

Transpiration-Cooled Spacecraft-Insulation-Repair Fasteners

Transpiration-cooled fasteners are proposed that operate like an open-loop heat pipe (self-tapping screws, bolts, and spikes) for use in on-orbit repair of thermal- insulation of a space shuttle or other spacecraft. By limiting the temperature rise of such a fastener and of the adjacent repair material and thermal protection system, the transpiration cooling would contribute to the ability of the repair to retain its strength and integrity in the high-heat-flux, oxidizing environment of reentry into the atmosphere of the Earth. A typical fastener according to the proposal would include a hollow refractory-metal, refractory-composite, or ceramic screw or bolt, the central cavity of which would be occupied by a porous refractory- metal or ceramic plug that would act as both a reservoir and a wick for a transpirant liquid. The plug dimensions, the plug material, and the sizes of the pores would be chosen in conjunction with the transpirant liquid so that (1) capillary pumping could be relied upon to transport the liquid to the heated surface, where the liquid would be vaporized, and (2) the amount of liquid would suffice for protecting against the anticipated heat flux and integrated heat load