604 research outputs found
Kink-antikink interactions in the double sine-Gordon equation and the problem of resonance frequencies
We studied the kink-antikink collision process for the "double sine-Gordon"
(DSG) equation in 1+1 dimensions at different values of the potential parameter
. For small values of we discuss the problem of resonance frequencies.
We give qualitative explanation of the frequency shift in comparison with the
frequency of the discrete level in the potential well of isolated kink. We show
that in this region of the parameter the effective long-range interaction
between kink and antikink takes place.Comment: 9 pages, LaTeX, 4 figures (eps
PCN197 Treatment Patterns and Baseline Characteristics of a Prospective Cohort of Patients with Advanced NSCLC Treated in Real World Community Oncology Settings
Shock compression and spallation of single crystal tantalum
We present molecular dynamics simulations of shock-induced plasticity and spall damage in single crystal Ta described by a recently developed embedded-atom-method (EAM) potential and a volumedependent qEAM potential. We use impact or Hugoniotstat simulations to investigate the Hugoniots, deformation and spallation. Both EAM and qEAM are accurate in predicting, e.g., the Hugoniots and γ - surfaces. Deformation and spall damage are anisotropic for Ta single crystals. Our preliminary results show that twinning is dominant for [100] and [110] shock loading, and dislocation, for [111]. Spallation initiates with void nucleation at defective sites from remnant compressional deformation or tensile plasticity. Spall strength decreases with increasing shock strength, while its rate dependence remains to be explored
Export production fluctuations in the eastern equatorial Pacific during the Pliocene-Pleistocene: Reconstruction using barite accumulation rates
published_or_final_versio
Coupled Mg/Ca and Clumped Isotope Measurements Indicate Lack of Substantial Mixed Layer Cooling in the Western Pacific Warm Pool During the Last ∼5 Million Years
The Indo-Pacific Warm Pool (IPWP) plays a crucial role in influencing climate dynamics both in the tropics and globally. Yet, there is an ongoing controversy concerning the evolution of surface temperatures in the IPWP since the Pliocene, which is fueled by contradictory proxy evidence. Temperature reconstructions using TEX86 indicate a gradual cooling by ∼2°C from the Pliocene to today while Mg/Ca-based studies using planktonic foraminifera do not report any long-term trends. A bias in Mg/Ca records due to seawater chemistry changes has been suggested as an explanation for this proxy mismatch. Here, we present data from two independent foraminifera-based temperature proxies, Mg/Ca and clumped isotopes (Δ47), measured on the same samples from IODP Site U1488 in the IPWP. We reconstructed mixed layer and subsurface temperatures and find very good agreement among Mg/Ca and Δ47 when applying a minor correction for changing Mg/Ca ratios of seawater. Diagenetic effects could influence Δ47 but the evaluation of foraminifera preservation at Site U1488 suggests that this effect is unlikely to have masked a long-term trend in the data. While remaining uncertainties prevent us from fully ruling out particular hypotheses, our study adds evidence that mixed layer temperatures likely did not cool substantially, while subsurface temperatures cooled more strongly since the Pliocene. The substantial Pleistocene cooling previously observed in TEX86 data is consistent with this finding when interpreting it as a combined surface and subsurface signal.publishedVersio
IODP Expedition 323—Pliocene and Pleistocene Paleoceanographic Changes in the Bering Sea
High-resolution paleoceanography of the Plio-Pleistocene is important in understanding climate forcing mechanisms and the associated environmental changes. This is particularly true in high-latitude marginal seas such as the Bering Sea, which has been very sensitive to changes in global climate during interglacial and glacial or Milankovitch time scales. This is due to significant changes in water circulation, land-ocean interaction, and sea-ice formation. With theaim to reveal the climate and oceanographic history of the Bering Sea over the past 5 Ma, Integrated Ocean Drilling Program (IODP) Expedition 323 cored a total of 5741 meters of sediment (97.4% recovery) at seven sites covering three different areas: Umnak Plateau, Bowers Ridge, and the Bering slope region. Four deep holes range from 600 m to 745 m spanning in age from 1.9 Ma to 5 Ma. The water depths (819 m to 3173 m) allow characterization of past verticalwater mass distribution such as the oxygen minimum zone (OMZ). The results highlight three key points. (1) The first is an understanding of long-term evolution of surface-water mass distribution during the past 5 Ma including past sea-ice distribution and warm and less eutrophic subarctic Pacific water mass entry into the Bering Sea. (2) We characterized relatively stagnant intermediate water mass distribution imprinted as laminated sediment intervals that have beenubiquitously encountered. Today, the OMZ impinges upon the sediments at ~700–1600 m water depths. In the past, the OMZ appears to have occurred mainly during interglacial periods. Changes in low oxygen-tolerant benthic foraminiferal faunas clearly concur with this observation. (3) We also characterized significant changes between glacial episode of terrigenous sedimentary supply and interglacialepisode of diatom flux
NMO in pediatric patients: brain involvement and clinical expression
Abstract
Objective: To analyze the clinical, neuroimaging characteristics and positivity of the acquaporin water channel (NMO-IgG) in pediatric patients with neuromyelitis optica (NMO). This disorder could have a variable clinical expression. To address such variability, the term NMO spectrum has been suggested.
Method: We evaluated six pediatric patients, with a median age of 11 years at the time of the study, with the diagnosis of NMO by the Wingerchuck criteria.
Results: All the cases exhibited bilateral optic neuritis (ON). Four patients had abnormalities on brain MRI from the onset,although only three of them developed symptoms correlated to those lesions during the course of their disorder. NMO-IgG was positive in 80%.
Conclusion: Optic neuropathy is the most impaired feature in NMO patients. Brain MRI lesions are not compatible with multiple sclerosis and positivity of the NMO-IgG are also present in NMO pediatric patients, confirming the heterogeneity in the expression of this disorder.
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RESUMEN
Objetivo: Analizar las características clínicas y de neuroimagen, y la positividad del canal de agua acuaporin (NMO-IgG) en pacientes pediátricos con neuromielitis óptica (NMO). Este trastorno puede tener una expresión clínica variable. El término espectro de NMO ha sido propuesto para poder incluir la variabilidad.
Metodo: Evaluamos seis pacientes pediátricos, con una mediana de edad de 11 años al momento del estudio, con el diagnóstico de NMO de acuerdo a los criterios de Wingerchuck.
Resultados: Todos los casos exhibían neuritis óptica bilateral (ON). Cuatro pacientes tuvieron anormalidades en la RM cerebral desde el inicio, aunque solo tres de ellos desarrollaron síntomas relacionados con las lesiones durante el curso de la enfermedad. NMO-IgG fue positiva en el 80%.
Conclusión: Neuropatía óptica es la característica mayormente observada en los pacientes con NMO. Lesiones cerebrales en la RM cerebral no compatibles con esclerosis multiple y positividad de la NMO-IgG están también presentes en los pacientes pediátricos con NMO; lo cual confirma la heterogeneidad en la expresión clínica de este trastorno
Medida de umidade do solo com sonda de nêutrons nas proximidades da superfície
The problem of neutron probe soil water content measurements close to soil surface is analysed from the spatial variability and also from the slow neutron "loss" to the atmosphere points of view. Results obtained on a dark red latosol of the county of Piracicaba,SP, indicate the possibility of precisely measuring the neutron "sphere of influence" when different media are used on soil surface.O problema da medida da umidade nas proximidades da superfície do solo é abordado do ponto de vista de sua variabitidade espacial e da "perda" de nêutrons lentos para a atmosfera. Dados, obtidos em terra roxa estruturada do município de Piracicaba,SP, mostram a possibilidade de se avaliar, com precisão, a "esfera de influência" da medida, quando se utilizam meios diferentes na superfície do solo
Investigation of correlations between clinical signs and pathological findings in cats and dogs with inflammatory bowel disease
This paper compares the correlation between the clinical signs and the histopathological observations of the entire intestine in cats and dogs with inflammatory bowel disease (IBD). To perform this study, hospital records of 53 dogs and 20 cats of different sex, ages, and breed diagnosed with IBD following the histopathological criteria of the World Small Animal Veterinary Association (WSAVA) were evaluated. The results obtained in this study did show correlations between some clinical signs and the histopathological assessment of dogs and cats with IBD. Therefore, a slight association between diarrhea and lacteal dilation in the small bowel, and diarrhea and desquamation in the large bowel of dogs with IBD was seen, but no other associations were found between the rest of the lesions and symptoms. In contrast, cats only showed a correlation between anorexia with villous stunting and villous epithelial injury, without correspondence among other clinical signs and lesions. The results of this study propose that the evaluation of IBD can be complicated, especially with the use of retrospective records of archived intestinal biopsies and subjective clinical and histopathologic decisions
Data report: composite depth scale and splice revision for IODP Site U1488 (Expedition 363 Western Pacific Warm Pool) using XRF core scanning data and core images
The Western Pacific Warm Pool (WPWP) is a major source of heat and moisture to the atmosphere. Small perturbations in WPWP sea-surface temperatures greatly influence local Hadley and Walker cells, thereby affecting global atmospheric circulation patterns. International Ocean Discovery Program (IODP) Expedition 363 sought to document the regional expression and driving mechanisms of WPWP climate variability during the Neogene on millennial, orbital, and geological timescales. Located in the heart of the WPWP, IODP Site U1488 (02°02.59ʹN, 141°45.29ʹE) was drilled in 2604 m water depth on the southern part of the Eauripik Rise in the Caroline Basin. At Site U1488, a continuous shipboard composite stratigraphic section from 0 to ~331 m core composite depth below seafloor (CCSF) was compiled using high-resolution shipboard physical property data from three holes. This section comprises upper Miocene to recent foraminifer-rich nannofossil ooze and foraminifer-nannofossil ooze, making Site U1488 ideally suited to reconstruct the paleoceanographic history of the central WPWP region. However, the high carbonate content (>90% below ~180 m CCSF) of Site U1488 sediments means that the physical property data sets commonly used for splice construction (gamma ray attenuation bulk density, magnetic susceptibility, and natural gamma radiation) were too low amplitude to provide robust constraints on splice tie points below 120 m CCSF. As a result, P-wave data, which are relatively untested as a correlation tool, became critical for correlating between holes. Here, we verify and extend the Site U1488 shipboard composite splice using high-resolution (2 cm) X-ray fluorescence Ba/Sr core scanning data combined with composite linescan images. Overall, using these data at Site U1488 resulted in revised core offsets that differ by up to 0.84 m relative to the shipboard core offsets and a composite depth scale down to 329.33 m revised CCSF. The revised splice will allow optimization of postexpedition research and ensure that high-resolution studies of Site U1488 are conducted on a continuous stratigraphic section
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