How Sensitive is the CMB to a Single Lens?

We study the imprints of a single lens, that breaks statistical isotropy, on the CMB and calculate the signal to noise ratio (S/N) for its detection. We emphasize the role of non-Gaussianities induced by LCDM weak lensing in this calculation and show that typically the S/N is much smaller than expected. In particular we find that the hypothesis that a void (texture) is responsible for the WMAP cold spot can barely (cannot) be tested via weak lensing of the CMB.Comment: Accepted for publication in JCAP, 24 pages, 5 figure

CMB Imprints of a Pre-Inflationary Climbing Phase

We discuss the implications for cosmic microwave background (CMB) observables, of a class of pre-inflationary dynamics suggested by string models where SUSY is broken due to the presence of D-branes and orientifolds preserving incompatible portions of it. In these models the would-be inflaton is forced to emerge from the initial singularity climbing up a mild exponential potential, until it bounces against a steep exponential potential of "brane SUSY breaking" scenarios, and as a result the ensuing descent gives rise to an inflationary epoch that begins when the system is still well off its eventual attractor. If a pre-inflationary climbing phase of this type had occurred within 6-7 e-folds of the horizon exit for the largest observable wavelengths, displacement off the attractor and initial-state effects would conspire to suppress power in the primordial scalar spectrum, enhancing it in the tensor spectrum and typically superposing oscillations on both. We investigate these imprints on CMB observables over a range of parameters, examine their statistical significance, and provide a semi-analytic rationale for our results. It is tempting to ascribe at least part of the large-angle anomalies in the CMB to pre-inflationary dynamics of this type.Comment: 38 pages, LaTeX, 11 eps figures, references added, matches version to appear in JCA

Gas Accretion and Galactic Chemical Evolution: Theory and Observations

This chapter reviews how galactic inflows influence galaxy metallicity. The goal is to discuss predictions from theoretical models, but particular emphasis is placed on the insights that result from using models to interpret observations. Even as the classical G-dwarf problem endures in the latest round of observational confirmation, a rich and tantalizing new phenomenology of relationships between $M_*$, $Z$, SFR, and gas fraction is emerging both in observations and in theoretical models. A consensus interpretation is emerging in which star-forming galaxies do most of their growing in a quiescent way that balances gas inflows and gas processing, and metal dilution with enrichment. Models that explicitly invoke this idea via equilibrium conditions can be used to infer inflow rates from observations, while models that do not assume equilibrium growth tend to recover it self-consistently. Mergers are an overall subdominant mechanism for delivering fresh gas to galaxies, but they trigger radial flows of previously-accreted gas that flatten radial gas-phase metallicity gradients and temporarily suppress central metallicities. Radial gradients are generically expected to be steep at early times and then flattened by mergers and enriched inflows of recycled gas at late times. However, further theoretical work is required in order to understand how to interpret observations. Likewise, more observational work is needed in order to understand how metallicity gradients evolve to high redshifts.Comment: Invited review to appear in Gas Accretion onto Galaxies, Astrophysics and Space Science Library, eds. A. J. Fox & R. Dav\'e, to be published by Springer. 29 pages, 2 figure

Effects of Changes in Sodium Balance on Prostaglandin Synthesis and Prostaglandin E2 9-Ketoreductase Activity in the Rat Kidney

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