262 research outputs found

    Special issue of Organic Agriculture — Organic 3.0

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    It is an honor to be able to present this special issue of Organic Agriculture: Organic 3.0 for the Organic World Congress in India 2017. In this issue, we have collected a number of papers relevant for the theme Organic 3.0. This special issue of Organic Agriculture about Organic 3.0 is published in connection to the science track “Innovative research for Organic 3.0” at the Organic World Congress in Delhi, India, November 2017. In the foreword to the proceedings (Rahmann et al. 2017), the challenges listed correspond well to those described and discussed in these five papers. The fact that the paper by Rahmann et al. (2016) that has been online in Organic Agriculture since December 2016, already after 6 months has been downloaded more than 3,000 times shows the great interest in this subject. Together, these papers give a valuable basis for the further discussion of Organic 3.0 and the future development for the organic sector and beyond. Organic agriculture—whether 2.0 or 3.0—can be one option to solve future problems, and the ideas behind organic agriculture should be integrated as much as possible in many types of agriculture: agroecological, small-holder, conventional, conservation tillage, etc. But organic agriculture should also learn from conventional and other types of agriculture and if necessary take a critical view on, e.g., minimum requirements that result in negative effects on public goods. Governments, NGO’s, farmers, researchers, and other stakeholders should all contribute to developing organic as well as other forms of agriculture. It is our hope that this special issue will be one step in bringing organic and truly sustainable agriculture forward

    Kinna-Uganda: A Review of Uganda\u27s National Cinema

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    Kinna-Uganda (K-U) is a form of cinema that has emerged in Uganda following decades of the totalitarian political regime of Idi Amin, which in turn followed almost a century of colonial rule. The concept of national cinema is evaluated in this thesis as a tool for analysis of K-U. The national cinema concept is compared with four other models -- regional, continental, Pan-African, and transnational -- that can also be used to analyze and deconstruct films and the academic space within which they reside. This study examines Uganda\u27s pre-colonial, colonial, and post-colonial times and their impact on the production of K-U and on Uganda\u27s film industry. This research also presents the dissemination of Africa\u27s cinema in the context of the African Diaspora and provides a guide to K-U and the Ugandan film industry from its inception until early 2010. In analyzing these findings of this study, it has been determined that the concept of national cinema is useful when dissecting K-U. The strength and utility of national cinema as a concept lies in four different factors: it aids in identifying K-U; it helps to explain the origins and characteristics of the local Ugandan film industry; it identifies the common constraints to expansion of the Ugandan film industry and, lastly, it helps in offering a prediction for the future of the Ugandan film industry. However, adhering to a strict definition of national cinema is shown to be less useful than previously in evaluating K-U, as it has propagated through Africa and increasingly involves co-productions between Ugandan and non-Ugandan entities

    Patterns of cetacean sighting distribution in the Pacific Exclusive Economic Zone of Costa Rica based on data collected from 1979-2001

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    Nineteen species of cetaceans (families Balaenopteridae, Kogiidae, Physeteridae, Ziphiidae and Delphinidae) occur in the Costa Rican Pacific Exclusive Economic Zone (EEZ). Based on data recorded from the EEZ by the Southwest Fisheries Service Center, Cascadia Research Collective, and CIMAR between 1979- 2001, we mapped the distribution of 18 cetacean species. Our results suggest that the majority of the cetacean species use primarily oceanic waters, particularly those species within the families Balaenopteridae, Kogiidae, Physeteridae and Ziphiidae. Members of the family Delphinidae showed a wide variety of distribution patterns: seven species are widespread throughout the EEZ, four appear to be exclusively pelagic, and two are primarily coastal. Overall, three cetacean species appear to have populations concentrated in coastal waters: Stenella attenuata graffmani, Tursiops truncatus, and Megaptera novaeangliae. These three may be more susceptible to human activities due to the overlap of their ranges with fishery areas (tuna and artisanal fisheries), and an uncontrolled increase of touristic whale watching activities in several parts of their range. The distribution maps represent the first comprehensive representation of cetacean species that inhabit Costa Rican Pacific waters. They provide essential base-line information that may be used to initiate conservation and management efforts of the habitats where these animals reproduce and forage

    Vaccination of patients with cutaneous melanoma with telomerase-specific peptides

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    Purpose: A phase I study was conducted to investigate the safety, tolerability, and immunological responses to vaccination with a combination of telomerase-derived peptides GV1001 (hTERT: 611-626) and p540 (hTERT: 540-548) using granulocyte-macrophage colony-stimulating factor (GM-CSF) or tuberculin as adjuvant in patients with cutaneous melanoma. Experimental design: Ten patients with melanoma stages UICC IIb-IV were vaccinated 8times intradermally with either 60 or 300nmole of GV1001 and p540 peptide using GM-CSF as adjuvant. A second group of patients received only 300nmole GV1001 in combination with tuberculin PPD23 injections. HLA typing was not used as an inclusion criterion. Peptide-specific immune responses were measured by delayed-type hypersensitivity (DTH) reactions, in vitro T cell proliferation assays, and cytotoxicity (51-Chromium release) assays for a selected number of clones subsequently generated. Results: Vaccination was well tolerated in all patients. Peptide-specific immune response measured by DTH reactions and in vitro response could be induced in a dose-dependent fashion in 7 of 10 patients. Cloned T cells from the vaccinated patients showed proliferative responses against both vaccine peptides GV1001 and p540. Furthermore, T cell clones were able to specifically lyse p540-pulsed T2 target cells and various pulsed and unpulsed tumor cell lines. Conclusion: These results demonstrate that immunity to hTERT can be generated safely and effectively in patients with advanced melanoma and therefore encourage further trial

    Kriterer for sirkulære bygg. Kartlegging av bransjestandard

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    Kriterier for sirkulære bygg - Kartlegging av bransjestandard Det er behov for videre metodeutvikling av sirkularitet i norske bygninger, inkludert målenheter, definisjoner, systemgrenser og kartlegging av bransjestandard. Denne rapporten samler nåværende statistikk og data for å sette «dagens» bransjestandard for sirkularitet i norske bygg. Resultatene viser at den norske byggenæringen er rundt 7% sirkulær i 2023 ifølge FutureBuilts sirkularitetsindeksmetode. Framskrivingene viser at sirkularitet kan være rundt 14-42% innen 2030 og 34-71% innen 2050 når en rekke politiske og strukturelle tiltak og endringer gjennomføres. Det vises også at dersom målet om full sirkularitet skal oppnås må det settes inn enda flere tiltak. Allikevel er det høye usikkerheter i datakvalitet på grunn av mange antagelser, mange datahull, og et lappeteppe av ulike datakilder. Resultatene fra denne studien er et første steg mot å kartlegge sirkularitet i den norske byggenæringen og viser at et mye mer detaljert datagrunnlag om sirkulær statistikk trengs for å redusere usikkerheter. Resultatene viser hvor mye som må til for at Norges byggenæring skal være fullt sirkulær. Disse resultatene er nyttige for blant annet videreutvikling av FutureBuilts sirkularitetsindeks og Grønn Byggallianses miljødashboard. ZEN partnere FutureBuilt, Bærum kommune, Oslo kommune, Statsbygg, Asplan Viak, og Multiconsult har bidratt til denne rapporten. I tillegg har Entra bidratt.publishedVersio

    Inside the clockwork of the ECHO factorial trial: A conceptual model with proposed mediators for prevention of emotional problems in children

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    Having interventions that are not only evidence-based and effective but also cost-effective and efficient is important for the prevention and treatment of child and adolescent emotional problems. A randomized clinical trial (RCT) tests the totalinterventions effect but does not address specific components of the intervention. In this article the hypothesis and a conceptual model of the ECHO study are presented and discussed. The ECHO intervention consists of three different components each containing two levels of intervention. By using a cluster randomized factorial design, children aged 8–12 at 40 schools across Norway will be randomized to eight different experimental conditions investigating the optimal balance between effect, cost-effectiveness, and efficiency. The article presents the design and the different components being tested and discusses how optimalization can be reached through this innovative design. The article also discusses how interventions can be improved by investigating and understanding the mechanisms of change within psychological interventions. For each of the three components in the study we consider the mediators that could be active within the intervention and how the study investigates such mediation. The results will contribute to a better understanding of how psychological interventions work and how we intend to optimize the EMOTION intervention

    Study Protocol of a factorial trial ECHO: Optimizing a group-based school intervention for children with emotional problems

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    Background - Youth mental health problems are a major public health concern. Anxiety and depression are among the most common psychological difficulties. The aim of this study is to evaluate an optimized version of a promising indicated group intervention for emotional problems. The program (EMOTION Coping Kids Managing Anxiety and Depression) targets school children 8–12 years with anxious and depressive symptoms and examines three factors. Factor 1 compares the standard EMOTION intervention delivered in 16 group-based sessions (Group), versus a partially-digital EMOTION intervention (DIGGI) delivered as eight group sessions and eight digital sessions. Both versions use virtual reality technology (VR) to improve behavioral experiments. Factor 2 compares parent participation in a 5-session parent group (high involvement) versus sharing information with parents via a brochure (low involvement). Factor 3 compares the use of a measurement and feedback system (MFS) designed to help group leaders tailor the intervention using feedback from children with no MFS. Methods - Using a cluster-randomized factorial design, 40 schools across Norway will be randomized to eight different experimental conditions based on three, two-level factors. To assess internalizing symptoms in children, children and their parents will be given self-report questionnaires pre-, post-, and one year after intervention. Parents also report on demographics, user satisfaction, personal symptoms and perception of family related factors. Teachers report on child symptoms and school functioning. Group leaders and the head of the municipal services report on implementation issues. The primary outcomes are changes in depressive and anxious symptoms. Some secondary outcomes are changes in self-esteem, quality of life, and user satisfaction. Questions regarding the consequences of the COVID-19 pandemic are included. Treatment fidelity is based on checklists from group leaders, and on user data from the participating children. Discussion - This study is a collaboration between three regional centers for child and adolescent mental health in Norway. It will provide knowledge about: (1) the effect of school-based preventive interventions on anxiety and depression in children; (2) the effect of feedback informed health systems, (3) the effect and cost of digital health interventions for children, and (4) the effect of parental involvement
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