A rare case of primary vaginal carcinoma in prolapsed uterus

Primary carcinoma is rare in gynaecological neoplasia. Vaginal carcinoma in prolapse uterus is extremely rare. We hereby present a case of 55-year-old P3L3 postmenopausal woman with complete uterine prolapse with fungating growth of 6x8 cm with two decubitus ulcers of 1x1 cm. Marginal biopsy showed well-differentiated squamous cell carcinoma of vagina. Investigation was done showed no metastasis. Patient was diagnosed with stage 2 disease. Patient underwent 5 cycles of chemotherapy with 2 cycles of radiotherapy and is being followed up. The importance of biopsy of ulcer in cases of UV prolapse in order to exclude malignancy to avoid incomplete treatment has been illustrated through this case. The need of careful evaluation of vaginal erosions in pelvic organ prolapse has been highlighted. As there is lack of well-defined treatment protocols for vaginal cancer with concurrent prolapse, the case also underlines the importance of a multidisciplinary approach involving gynaecological oncology, urogynaecology, medical oncology, surgical oncology and radiation oncology

An Experience at a Tertiary Level Hospital NRC in Management of Severe Acute Malnutrition in Children Aged between 6-59 Months Adopting World Health Organization Recommendations

Objectives: To study the outcome indicators of a nutritional rehabilitation center and to assess its performance.Design: Retrospective case study.Period: One year period from Jan 2014 to Dec 2014.Methods: Data of 254 children aged between 6-59 months with severe acute malnutrition admitted in nutritional rehabilitation center at department of pediatrics, Gandhi hospital, was analyzed retrospectively. Identification and treatment of severe acute malnutrition was done according to world health organization recommendations.Results: The recovery rate, death rate, defaulter rate, mean (SD) weight gain & mean (SD) duration of stay in the nutritional rehabilitation center were 51.42%, 3.54%, 28.57%, 8g/kg/day, 14.2 days respectively.Conclusions: Nutritional rehabilitation centers are effective in management of severe malnutrition and also in decreasing the case fatality rates

Synthesis, Characterization and Density Functional Study of LiMn1.5Ni 0.5O4 Electrode for Lithium ion Battery

This paper analyses material issues of development of Li-ion batteries to store electrical energy. The performance of the battery is improved by developing the high energy density cathode materials at Nano level. This paper explains the synthesis of most interesting cathode material Lithium Manganese Spinel and its derivatives like transition metal oxide (LiNi0.5Mn1.5O4) using Co-Precipitation chemical method; it is one of the eco-friendly ,effective, economic and easy preparation method. The structural features of LiNi0.5Mn1.5O4 was characterized by XRD – analysis indicated that prepared sample mainly belong to cubic crystal form with Fd3m space group ,with lattice parameter a 8.265 and average crystal size of 31.59 nm and compared the experimental results with computation details from first principle computation methods with Quantum wise Atomistix Tool Kit (ATK),Virtual Nano Lab. First principle computation methods provide important role in emerging and optimizing this electrode material. In this study we present an overview of the computation approach aimed at building LiNi0.5Mn1.5O4 crystal as cathode for Lithium ion battery. We show each significant property can be related to the structural component in the material and can be computed from first principle. By direct comparison with experimental results, we assume to interpret that first principle computation can help to accelerate the design & development of LiNi0.5Mn1.5O4 as cathode material of lithium ion battery for energy storage. When you are citing the document, use the following link http://essuir.sumdu.edu.ua/handle/123456789/3431

Effect of vaginal pH on efficacy of dinoprostone gel for labour induction

Background: Induction of labour is defined as an intervention designed to artificially initiate uterine contractions leading to progressive dilatation and effacement of the cervix and birth of the baby. The aim of the study was to evaluate the influence of vaginal pH on the efficacy of dinoprostone gel for labor induction.Methods: A prospective study conducted on 200 subjects within 1 year in India. The Bishop score and vaginal pH (with pH paper, Sigma Chemical Company, St. Louis, USA) of subjects undergoing induction of labor with dinoprostone gel was assessed prior induction. After 6 hours of induction, PGE2 gel was repeated or labor was augmented. The vaginal pH measured was compared with age, parity, Bishop Score, time to enter into active phase of labor, and the mode of delivery. The significance of association was calculated by Chi-square test.Results: Majority subjects had pH in the range 5-6.Subjects with higher parity were associated with higher vaginal ph. Higher vaginal pH was associated with a higher Bishop score prior to induction, responded to single induction, and had a higher  number of vaginal deliveries than those with lower vaginal pH. There was no significant association found in vaginal pH and the time taken to enter into active phase of labor. Subjects with pregnancy induced hypertension were found to have higher vaginal ph.Conclusions: Parity influences vaginal pH and vaginal pH itself has a significant effect on the Bishop Score prior induction. Hence knowing the vaginal pH prior induction could be a useful tool to assess the labor outcome in induction with PGE2

Synthesis, Characterization and Density Functional Study of LiMn1.5Ni 0.5O4 Electrode for Lithium ion Battery

This paper analyses material issues of development of Li-ion batteries to store electrical energy. The performance of the battery is improved by developing the high energy density cathode materials at Nano level. This paper explains the synthesis of most interesting cathode material Lithium Manganese Spinel and its derivatives like transition metal oxide (LiNi0.5Mn1.5O4) using Co-Precipitation chemical method; it is one of the eco-friendly ,effective, economic and easy preparation method. The structural features of LiNi0.5Mn1.5O4 was characterized by XRD – analysis indicated that prepared sample mainly belong to cubic crystal form with Fd3m space group ,with lattice parameter a 8.265 and average crystal size of 31.59 nm and compared the experimental results with computation details from first principle computation methods with Quantum wise Atomistix Tool Kit (ATK),Virtual Nano Lab. First principle computation methods provide important role in emerging and optimizing this electrode material. In this study we present an overview of the computation approach aimed at building LiNi0.5Mn1.5O4 crystal as cathode for Lithium ion battery. We show each significant property can be related to the structural component in the material and can be computed from first principle. By direct comparison with experimental results, we assume to interpret that first principle computation can help to accelerate the design & development of LiNi0.5Mn1.5O4 as cathode material of lithium ion battery for energy storage. When you are citing the document, use the following link http://essuir.sumdu.edu.ua/handle/123456789/3581

Existence and nonexistence of positive solutions for a n-th order three-point boundary value problem

The purpose of this paper is to establish some results on the existence and nonexistence of positive solutions for a type of nonlinear n-th order three-point boundary value problems. The main tool is a fixed point theorem of the cone expansion and compression of functional type due to Avery, Anderson, and O’Regan. Some examples are presented to illustrate the availability of the main results.Publisher's Versio

Analyzing the short term and long-term complication of hysterectomy: a prospective study

Background: Hysterectomy is the most common surgical procedure done worldwide in women. Although many studies were done regarding short term complications, long term complications are not very well followed up. The objective of the study is to analyze short term and also long-term complications for the different mode of hysterectomy.Methods: It was a time-bound hospital-based prospective study which includes all the women who underwent hysterectomy for benign conditions in the hospital except women with prior psychiatric, bowel, bladder and sexual dysfunctions. All the patients were followed up for one year using a set of questionnaires to study short term and long-term complications.Results: No significant difference in short term post-operative complications concerning the mode of hysterectomy except for UTI was more common in vaginal hysterectomy group and haemorrhage in TAH route. Sexual dysfunction was noted even after 1 year of surgery in all modes of hysterectomy. Mild urinary dysfunction found statistically significant even at 1 year follow up in vaginal hysterectomy mode however there was no bothersome urinary dysfunction persistent after one year.Conclusions: Sexual dysfunction is the most common persistent long-term morbidity following hysterectomy found in the present study