Political Leaders’ Communication: A Twitter Sentiment Analysis during Covid-19 Pandemic

The pandemic made it critical for political leaders to intensify measures in fight against Covid-19 and one such measure was building trust among public through communication. With exponential growth in reach of social media, while state political leaders have progressively used internet for election campaigns, limited studies have explored as to how leaders use this medium to communicate during crisis, what kind of information do they share and what are common issues addressed. This paper, using qualitative research design, analyses Indian political leaders’ communication on Twitter. Sentiment Analysis was carried to identify and extract subjective information in leaders’ communication using 29 Indian political leaders, where in 12.128 tweets were extracted. Subjectivity scores depicted more than half of leaders had shared fact-based information, and Polarity scores indicated that almost 90% of leaders shared positive or neutral information thus leading to an inference that leaders share more of facts based and positive or neutral information rather than statements in form of opinions

Mobile App Based Feature Extraction of a Speech Signal

Mobile phones are very much prevalent in today?s generation. They can be utilized in the diagnosis and treatment of many diseases. The traditional methods which are used for the diagnosis of the vocal cord disorder are usually invasive, expensive and slow. Sometimes, they are also annoying. So the purpose of this paper is to design a non-invasive technique for the feature extraction of speech signal which can later be used for the vocal cord disorder diagnosis which would be cheaper, faster and repeatable. This paper summarizes a study of the mobile app based technique used to extract features of a speech signal with an ultimate aim to discriminate and detect vocal cord disorder. The study is concentrated in the analysis of relevance of a set of features obtained from the analysis of phonated speech, specifically an open vowel as \a\. The features which are extracted for the mobile app are frequency, pitch, amplitude and jitter

DEVELOPMENT AND VALIDATION OF RP-HPLC METHOD FOR SIMULTANEOUS ESTIMATION OF AZILSARTAN MEDOXIMIL AND CHLORTHALIDONE IN BULK FORM AND FORMULATION USING QUALITY BY DESIGN

Objective: Development of an accurate, precise, robust, sensitive, economical and rapid isocratic reversed-phase high-performance liquid chromatography (RP-HPLC) method complying quality by design (QbD) trends for simultaneous estimation of azilsartan medoximil and chlorthalidone in bulk and formulation form and validation of the method as per ICH guidelines.Methods: The simultaneous estimation of the drugs-azilsartan and chlorthalidone was performed using C8 column having dimensions 150×4.6 mm×5 µm, injection volume 10 µl, flow rate 0.8 ml/min., runtime 10 min., column temperature 20 oC, sampler temperature 5 °C and ultraviolet detection using a photodiode array detector at 220 nm as constant. The optimized method was validated as per ICH guidelines.Results: The retention times for chlorthalidone and azilsartan medoxomil were 2.4 min. and 5.1 min. respectively with resolution 17. The method was validated as per the ICH guidelines. The linearity of chlortalidone and azilsartan medoxomil was in the range of 6.3 to 15 µg/ml and 20 to 48 µg/ml respectively. The potency of the formulation was found to be 108.12 % and 98.20 % respectively, which are within acceptable limits as per IP.Conclusion: Method validation results have proven the method to be selective, precise, accurate, and robust, as well as stability indicating. The C8 column used for analysis gave encouraging results with better resolution and less retention time. This method can be successfully applied for the routine analysis involving the determination of content uniformity and dissolution profiling as well as stability study by the industry.Keywords: RP-HPLC, QbD, ICH, Azilsartan medoximil, Chlorthalidone

Cassia auriculata: Aspects of Safety Pharmacology and Drug Interaction

Safety pharmacology studies help in identifying preclinical adverse drug reactions. We carried out routine safety pharmacology with focus on cardiovascular variables and pharmacokinetic herb-drug interaction studies on rats fed with standardized traditional hydro-alcoholic extract and technology-based supercritical extract of Cassia auriculata for 12 weeks. Our studies indicate that both these extracts are pharmacologically safe and did not show any significant adverse reactions at the tested doses. The traditional hydro-alcoholic extract did not show any significant effect on pharmacokinetics; however, the technology-based supercritical extract caused a significant reduction in absorption of metformin. Our results indicate the need to include pharmacokinetic herb-drug interaction studies as evidence for safety especially for technology-based extracts

DESIGN AND ANALYSIS OF QUADRIFILAR HELICAL ANTENNA FOR CUBE-SATS USING C-BAND FREQUENCY RANGE FOR SATELLITE COMMUNICATION

Design and analysis of quadrifilar helical antenna is presented in this paper. The proposed antenna is designed for cube-sats in the low earth and medium earth orbit applications. It is a combination of 4 helical antennas, each separated by 90o, with left-handedness and it is designed for operation at 4.5GHz. The proposed antenna has 11.11% impedance bandwidth. The antenna is designed in 2 steps to analyze its proper radiation pattern and input characteristics. The first step of designing is selection of a ground plane with perfect dimensions, which can operate at desired frequency. While the second step is to analyses the antenna performance for different helix angle using proper ground plane dimensions. The gain versus frequency curve has been obtained for desired frequency and it is showing more than 5 dB gain at resonant frequency 4.5 GHz. Thus, based on desired application proposed antenna has been designed

Bait specificity in Hook and line fishery of River Ganga and associated conservation issues

61-72Recent survey in lower 1,110 km stretch of River Ganga regarding ‘hook and line’ fishery revealed that fishers apply their inherited indigenous knowledge for selection of bait to harvest finfish and shellfish from river water. A total number of 26 different types of baits under 07 categories were recorded. Six varieties of fish species and four types of insects are found to be prevalent for catching carnivorous fishes. Five specially modified indigenous types of bait moulded with fish attractants were also documented. Bait-fish species association in hook and line fishery of river Ganga is discussed. Feeding habits of the target fishes was compared with the type of baits employed. Conservation issues associated with hook and line fishery is highlighted along with possible remedial measures. Different varieties of hook & line fishery which are in operation in river Ganga are briefly described. Indigenous Traditional Knowledge (ITK) associated with hook & line fishery needs to be properly documented and preserved for developing and encouraging ‘sport fishery’ in River Ganga

Bait specificity in Hook and line fishery of River Ganga and associated conservation issues

Recent survey in lower 1,110 km stretch of River Ganga regarding ‘hook and line’ fishery revealed that fishers apply their inherited indigenous knowledge for selection of bait to harvest finfish and shellfish from river water. A total number of 26 different types of baits under 07 categories were recorded. Six varieties of fish species and four types of insects are found to be prevalent for catching carnivorous fishes. Five specially modified indigenous types of bait moulded with fish attractants were also documented. Bait-fish species association in hook and line fishery of river Ganga is discussed. Feeding habits of the target fishes was compared with the type of baits employed. Conservation issues associated with hook and line fishery is highlighted along with possible remedial measures. Different varieties of hook & line fishery which are in operation in river Ganga are briefly described. Indigenous Traditional Knowledge (ITK) associated with hook & line fishery needs to be properly documented and preserved for developing and encouraging ‘sport fishery’ in River Ganga