1,240 research outputs found

    On-orbit Metrology and Calibration Requirements for Space Station Activities Definition Study

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    The Space Station is the focal point for the commercial development of space. The long term routine operation of the Space Station and the conduct of future commercial activities suggests the need for in-space metrology capabilities analogous when possible to those on-Earth. The ability to perform periodic calibrations and measurements with proper traceability is imperative for the routine operation of the Space Station. An initial review, however, indicated a paucity of data related to metrology and calibration requirements for in-space operations. This condition probably exists because of the highly developmental aspect of space activities to date, their short duration, and nonroutine nature. The on-orbit metrology and calibration needs of the Space Station were examined and assessed. In order to achieve this goal, the following tasks were performed: an up-to-date literature review; identification of on-orbit calibration techniques; identification of sensor calibration requirements; identification of calibration equipment requirements; definition of traceability requirements; preparation of technology development plans; and preparation of the final report. Significant information and major highlights pertaining to each task is presented. In addition, some general (generic) conclusions/observations and recommendations that are pertinent to the overall in-space metrology and calibration activities are presented

    Flaw Detection in Aluminum Welds by the Electric Current Perturbation Method

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    The integrity of the Space Shuttle external fuel tank is vital to the success of each shuttle mission. These giant tanks (154 ft long and 28 ft diameter) are manufactured for NASA by Martin Marietta Aerospace, New Orleans, LA. An important part of the quality assurance for each tank is detection of defects in the welds using nondestructive evaluation (NDE) methods. The tank is manufactured from aluminum panels which are welded together, and due to the large physical size of the tank, several thousand feet of weld must be inspected for each tank. Therefore, to be cost effective, the NDE methods used must not only be reliable but also must be rapid

    Density, dielectric and X-ray studies of Smectic A-Smectic A transitions

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    We report here the results of detailed density, dielectric and X-ray studies on three systems exhibiting different types of Smectic A-Smectic A transitions. It is found that although the layer spacing shows marked changes at the transitions, the corresponding density changes are extremely small. In every case studied, the dielectric anisotropy shows a pronounced decrease on going over to the lower temperature smectic A phase. This decrease can be correlated with the structural changes

    Chemical approaches to the re-structuring of proteins

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    Methodologies for protein re-structuring have been developed enabling site specific side chain modification to either coded or non-coded residues. Procedures for the modification of the protein profile by attachment of either pendants or structural motifs have been delineated. Selectivity has been demonstrated on the basis of modulation of the -CH2- spacer, which interposes the functional group and the peptide backbone

    Spiral Evolution in a Confined Geometry

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    Supported nanoscale lead crystallites with a step emerging from a non-centered screw dislocation on the circular top facet were prepared by rapid cooling from just above the melting temperature. STM observations of the top facet show a nonuniform rotation rate and shape of the spiral step as the crystallite relaxes. These features can be accurately modeled using curvature driven dynamics, as in classical models of spiral growth, with boundary conditions fixing the dislocation core and regions of the step lying along the outer facet edge.Comment: 4 pages, 3 figures, to be published in Physical Review Letter

    Assessment of respiratory compliance in infants with cystic fibrosis

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    लाख शब्दावली (अंग्रेजी - हिंदी) Technical terms related to Lac

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    लाख शब्दावली (अंग्रेजी - हिंदी) Technical terms related to La

    An evaluation of the TRIPS computer system

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    The TRIPS system employs a new instruction set architecture (ISA) called Explicit Data Graph Execution (EDGE) that renegotiates the boundary between hardware and software to expose and exploit concurrency. EDGE ISAs use a block-atomic execution model in which blocks are composed of dataflow instructions. The goal of the TRIPS design is to mine concurrency for high performance while tolerating emerging technology scaling challenges, such as increasing wire delays and power consumption. This paper evaluates how well TRIPS meets this goal through a detailed ISA and performance analysis. We compare performance, using cycles counts, to commercial processors. On SPEC CPU2000, the Intel Core 2 outperforms compiled TRIPS code in most cases, although TRIPS matches a Pentium 4. On simple benchmarks, compiled TRIPS code outperforms the Core 2 by 10% and hand-optimized TRIPS code outperforms it by factor of 3. Compared to conventional ISAs, the block-atomic model provides a larger instruction window, increases concurrency at a cost of more instructions executed, and replaces register and memory accesses with more efficient direct instruction-to-instruction communication. Our analysis suggests ISA, microarchitecture, and compiler enhancements for addressing weaknesses in TRIPS and indicates that EDGE architectures have the potential to exploit greater concurrency in future technologies

    Diverse Clinical Isolates of Mycobacterium tuberculosis Develop Macrophage-Induced Rifampin Tolerance.

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    The Mycobacterium tuberculosis lineage 4 strains CDC1551 and H37Rv develop tolerance to multiple antibiotics upon macrophage residence. To determine whether macrophage-induced tolerance is a general feature of clinical M. tuberculosis isolates, we assessed macrophage-induced drug tolerance in strains from lineages 1-3, representing the other predominant M. tuberculosis strains responsible for tuberculosis globally. All 3 lineages developed isoniazid tolerance. While lineage 1, 3, and 4 strains developed rifampin tolerance, lineage 2 Beijing strains did not. Their failure to develop tolerance may be explained by their harboring of a loss-of-function mutation in the Rv1258c efflux pump that is linked to macrophage-induced rifampicin tolerance
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