Juno Beach D-Day, 6 June 1944

Public history poster on Canada’s military past about Juno beach D-Day, by students Rances Fonseca Cespedes, Keirsten Kandhai, Fiorelli Lagdamen, Jocelynne Marcoux.https://source.sheridancollege.ca/swfhass_military_posters/1000/thumbnail.jp

Implementación de un sistema de gestión contable y comercial en la nube y su incidencia en los procesos operativos de la empresa Grifo Pam Pam y Mave S.A.C., Distrito de Marca – Huaraz, años 2019 - 2020

El actual estudio se efectuó con el objetivo de determinar la Implementación de un sistema de gestión contable y comercial en la nube y su incidencia en los procesos operativos de la empresa Grifo Pam Pam y Mave S.A.C. distrito de Marca – Huaraz, años 2019 – 2020, metodológicamente, este estudio se da de acuerdo a la técnica de constatación; siendo el diseño de la investigación de forma aplicada, según estando de acuerdo a la orientación, y explicativa, mediante las técnicas de contrastación; siendo el diseño de investigación de forma pre experimental, donde se tiene como población a 7 trabajadores. Sus técnicas que se empleo fue el análisis documental, el cuestionario y la encuesta. Además de ello se aplicó el cuestionario, la entrevista y la ficha de análisis documental como los instrumentos de las operaciones de la empresa. El desarrollo de los datos del pre y post test se demostró que la utilización del sistema Edsuite, incurre en la mejora de la gestión contable y comercial de la empresa Grifo Pam Pam y Mave S.A.C. distrito de Marca – Huaraz, años 2019 - 2020. Logrando que, en el grupo pre test el 71% (5) trabajadores se observa un bajo nivel de gestión contable y el 29% (2) trabajadores se observa un nivel medio, en el grupo post test el 57% (4) trabajadores se tiene un nivel medio y el 43% (3) trabajadores tienen un nivel alto. Al usar la T de Student con nivel de significancia del 5% (0,05) se determinó que la implementación del sistema Edsuite mejora la gestión contable y comercial de la empresa Grifo Pam Pam y Mave S.A.C. distrito de Marca – Huaraz, años 2019 - 2020; de forma se corrobora la hipótesis desarrolladaThe current study was carried out with the objective of determining the implementation of an accounting and commercial management system in the cloud and its impact on the operating processes of the Grifo Pam Pam y Mave S.A.C. Marca district - Huaraz, years 2019-2020, methodologically, this study is given according to the verification technique; being the design of the investigation in an applied way, according to being according to the orientation, and explanatory, by means of the contrasting techniques; The research design is pre-experimental, where the population is 7 workers. His techniques that were used were the documentary analysis, the questionnaire and the survey. In addition to this, the questionnaire, the interview and the document analysis sheet were applied as the instruments of the company's operations. The development of the pre and post test data showed that the use of the EDSUITE system, incurs in the improvement of the accounting and commercial management of the company Grifo Pam Pam y Mave S.A.C. Marca district - Huaraz, years 2019 - 2020. Achieving that, in the pre-test group 71% (5) workers observe a low level of accounting management and 29% (2) workers observe a medium level, in the post-test group 57% (4) workers have a medium level and 43% (3) workers have a high level. When using the Student's t test with a significance level of 5% (0.05), it was determined that the implementation of the EDSUITE system improves the accounting and commercial management of the company Grifo Pam Pam y Mave S.A.C. Marca district - Huaraz, years 2019 - 2020; the hypothesis developed is corroboratedTesi

Aplicación de la ingeniería de métodos para mejorar la productividad del área de producción en la empresa Fusimec S.R.L., 2021

La investigación titulada "Aplicación de métodos de ingeniería para mejorar la productividad de la empresa Inversiones & Proyectos Fusimec S.R.L., 2020", la compañía se especializa en la producción de productos metálicos y piezas estructurales de acero, bronce, hierro y aluminio. Uno de los grandes problemas que tiene la compañía es no tener un control en los tiempos por cada operación de fabricación de ruedas de acero lo que conlleva a la baja productividad, es por ello que el objetivo principal del estudio fue determinar como la ingeniería de métodos mejora la productividad del área de producción en la Empresa Fusimec S.R.L., 2021. La población para este estudio es un volumen de producción de ruedas de acero en un periodo de 30 días, así mismo se tomas tiempos para la prueba previa y posterior que se llevan a cabo para que las hipótesis puedan ser probadas posteriormente. El tipo de investigación es de enfoque cuantitativo y de diseño ha sido cuasi experimental, la cual se efectuó la observación y recolección de datos de los procedimientos a lo largo de los meses agosto septiembre y posterior a la implementación durante el mes de octubre y noviembre; de tal manera que se pudo observar el comportamiento de las variables mediante los instrumentos que se aplicaron en una pre y post prueba. Los resultados fueron procesados a través del SPSS V25 para analizar la contrastación de una aceptación o rechazo de la hipótesis. Según los resultados obtenidos se concluye que Implementación de la ingeniería de métodos mejora significativamente la productividad del área de producción en la Empresa Fusimec S.R.L., 2021, en tanto que con el uso de la estadística queda quedado demostrado que la media de la productividad antes (64.53 %) fue menor a la media después (79.95 %), respaldando la hipótesis

Distribución del gecko introducido <em>Hemidactylus frenatus<em> (Dumeril y Bribon 1836) (Squamata: Gekkonidae) en Colombia

The common house gecko, Hemidactylus frenatus, is a native species from Asia and the Indo-Pacific region. It has been found extensively in areas of the tropics both in the Old as well as the New World. Through the revision of museum specimens, we found 32 H. frenatus that have been erroneously identified with another invasive species, H. angulatus. The first record of H. frenatus in Colombia was reported in 2000 from the Magdalena Medio region, since that date to the present, the species has been founded in different localities into the Caribbean, Andean valleys, Pacific coastal and Orinoquia. The species has predilection for urban and suburban environments, but no records exist on its natural environment. According to our observations, this gecko is now more abundant than its conspecific, H. angulatus, and therefore we assume a strong competition between both species as well as other native and exotic geckos, mainly those that inhabit the San Andrés and Providencia islands. We recommend future studies that examine the degree of pressure and competition of H. frenatus on other native and exotic species of lizards

Distribución del gecko introducido Hemidactylus frenatus (Dumeril y Bribon 1836) (Squamata: Gekkonidae) en Colombia

The common house gecko, Hemidactylus frenatus, is a native species from Asia and the Indo-Pacific region. It has been found extensively in areas of the tropics both in the Old as well as the New World. Through the revision of museum specimens, we found 32 H. frenatus that have been erroneously identified with another invasive species, H. angulatus. The first record of H. frenatus in Colombia was reported in 2000 from the Magdalena Medio region, since that date to the present, the species has been founded in different localities into the Caribbean, Andean valleys, Pacific coastal and Orinoquia. The species has predilection for urban and suburban environments, but no records exist on its natural environment. According to our observations, this gecko is now more abundant than its conspecific, H. angulatus, and therefore we assume a strong competition between both species as well as other native and exotic geckos, mainly those that inhabit the San Andrés and Providencia islands. We recommend future studies that examine the degree of pressure and competition of H. frenatus on other native and exotic species of lizards.El gecko casero Hemidactylus frenatus es originario de Asia y la región Indo-Pacífica pero se ha distribuido en grandes áreas de las zonas tropicales del Viejo y Nuevo mundo. Por medio de la revisión de ejemplares de museos se encontraron 32 H. frenatus, que habían sido erróneamente identificados con otra especie introducida de este género, Hemidactylus angulatus. El primer registro de H. frenatus para Colombia se hizo en el 2000 en la región del Magdalena Medio, desde esa fecha hasta el presente, se encontraron reportes de esta especie en varias localidades del Caribe, los valles interandinos, la costa Pacífica y la Orinoquía. La especie ha mostrado predilección por ambientes urbanos y suburbanos y nunca se ha detectado en ambientes naturales. De acuerdo con las observaciones realizadas en Colombia, este gecko es ahora mucho más abundante que su co-específico H. angulatus, lo que puede indicar una fuerte competencia con éste y otras especies nativas, especialmente en las islas de San Andrés y Providencia. Se recomienda realizar estudios que permitan determinar el grado de presión y competencia que puede estar ejerciendo H. frenatus sobre especies nativas e introducidas de lagartijas

On the path to rabies elimination: The need for risk assessments to improve administration of post-exposure prophylaxis.

Costs of rabies post-exposure prophylaxis (PEP) often remain high in regions where rabies has been controlled in dogs, presenting a challenge for sustaining rabies elimination programmes. We investigated the potential for bite patient risk assessments to improve PEP provision and surveillance in settings approaching elimination of dog-mediated rabies. We conducted a longitudinal study of patients presenting to animal bite treatment centres (ABTCs) on the island province of Bohol in the Philippines to investigate the health status of biting dogs and to quantify current expenditure on PEP. Incidence of bite patients presenting to ABTCs was high (&gt;300/100,000 persons/year) and increasing, resulting in substantial health provider costs. Over $142,000 was spent on PEP in 2013 for a population of 1.3 million. From follow up of 3820 bite patients we found that  &gt;92% were bitten by healthy dogs (alive 14 days after the bite) and just 1.4% were bitten by probable or confirmed rabid dogs. The status of dogs that bit 6% of patients could not be determined. During the course of investigations of bites by suspect dogs, we were able to obtain samples for case confirmation, identify exposed persons who had not sought PEP as well as in-contact dogs at risk of developing rabies. We calculate that expenditure on PEP could at least be halved through more judicious approaches to provision of PEP, based on the histories of biting animals determined through risk assessments with bite patients. We conclude that a One Health approach to surveillance based on Integrated Bite Case Management could improve the sustainability and effectiveness of rabies elimination programmes while also improving patient care by identifying those genuinely in need of lifesaving PEP

The AWED trial (Applying Wolbachia to Eliminate Dengue) to assess the efficacy of Wolbachia-infected mosquito deployments to reduce dengue incidence in Yogyakarta, Indonesia: study protocol for a cluster randomised controlled trial.

BACKGROUND: Dengue and other arboviruses transmitted by Aedes aegypti mosquitoes, including Zika and chikungunya, present an increasing public health challenge in tropical regions. Current vector control strategies have failed to curb disease transmission, but continue to be employed despite the absence of robust evidence for their effectiveness or optimal implementation. The World Mosquito Program has developed a novel approach to arbovirus control using Ae. aegypti stably transfected with Wolbachia bacterium, with a significantly reduced ability to transmit dengue, Zika and chikungunya in laboratory experiments. Modelling predicts this will translate to local elimination of dengue in most epidemiological settings. This study protocol describes the first trial to measure the efficacy of Wolbachia in reducing dengue virus transmission in the field. METHODS/DESIGN: The study is a parallel, two-arm, non-blinded cluster randomised controlled trial conducted in a single site in Yogyakarta, Indonesia. The aim is to determine whether large-scale deployment of Wolbachia-infected Ae. aegypti mosquitoes leads to a measurable reduction in dengue incidence in treated versus untreated areas. The primary endpoint is symptomatic, virologically confirmed dengue virus infection of any severity. The 26 km2 study area was subdivided into 24 contiguous clusters, allocated randomly 1:1 to receive Wolbachia deployments or no intervention. We use a novel epidemiological study design, the cluster-randomised test-negative design trial, in which dengue cases and arbovirus-negative controls are sampled concurrently from among febrile patients presenting to a network of primary care clinics, with case or control status classified retrospectively based on the results of laboratory diagnostic testing. Efficacy is estimated from the odds ratio of Wolbachia exposure distribution (probability of living in a Wolbachia-treated area) among virologically confirmed dengue cases compared to test-negative controls. A secondary per-protocol analysis allows for individual Wolbachia exposure levels to be assessed to account for movements outside the cluster and the heterogeneity in local Wolbachia prevalence among treated clusters. DISCUSSION: The findings from this study will provide the first experimental evidence for the efficacy of Wolbachia in reducing dengue incidence. Together with observational evidence that is accumulating from pragmatic deployments of Wolbachia in other field sites, this will provide valuable data to estimate the effectiveness of this novel approach to arbovirus control, inform future cost-effectiveness estimates, and guide plans for large-scale deployments in other endemic settings. TRIAL REGISTRATION: ClinicalTrials.gov, identifier: NCT03055585 . Registered on 14 February 2017

An Anomalous Type IV Secretion System in Rickettsia Is Evolutionarily Conserved

Bacterial type IV secretion systems (T4SSs) comprise a diverse transporter family functioning in conjugation, competence, and effector molecule (DNA and/or protein) translocation. Thirteen genome sequences from Rickettsia, obligate intracellular symbionts/pathogens of a wide range of eukaryotes, have revealed a reduced T4SS relative to the Agrobacterium tumefaciens archetype (vir). However, the Rickettsia T4SS has not been functionally characterized for its role in symbiosis/virulence, and none of its substrates are known.Superimposition of T4SS structural/functional information over previously identified Rickettsia components implicate a functional Rickettsia T4SS. virB4, virB8 and virB9 are duplicated, yet only one copy of each has the conserved features of similar genes in other T4SSs. An extraordinarily duplicated VirB6 gene encodes five hydrophobic proteins conserved only in a short region known to be involved in DNA transfer in A. tumefaciens. virB1, virB2 and virB7 are newly identified, revealing a Rickettsia T4SS lacking only virB5 relative to the vir archetype. Phylogeny estimation suggests vertical inheritance of all components, despite gene rearrangements into an archipelago of five islets. Similarities of Rickettsia VirB7/VirB9 to ComB7/ComB9 proteins of epsilon-proteobacteria, as well as phylogenetic affinities to the Legionella lvh T4SS, imply the Rickettsiales ancestor acquired a vir-like locus from distantly related bacteria, perhaps while residing in a protozoan host. Modern modifications of these systems likely reflect diversification with various eukaryotic host cells.We present the rvh (Rickettsiales vir homolog) T4SS, an evolutionary conserved transporter with an unknown role in rickettsial biology. This work lays the foundation for future laboratory characterization of this system, and also identifies the Legionella lvh T4SS as a suitable genetic model