Features of childhood acute myeloid leukemia in Iran: A report from double center study

Acute Myeloblastic Leukemia is one of the important malignancies in children. For better managing the prognosis of this disease, there should be enough information about common features of this malignancy. The aim of this study was to evaluate these common features in children with Acute Myeloblastic Leukemia. A total of 104 eligible children less than 15-year-old have been referred from 2007-2011 to two referral centers for childhood malignancies. Basic epidemiological information recorded in checklists for each individual. Analyzes have been done by SPSS version 22. Out of patients, 57 cases were males (54.8). The male/female ratio was 1.2. The mean age of patients was 6.5 ± 4.3 years. The majority subtypes of patients were M3, M4, non-M3, and M2, respectively. The common molecular abnormalities were t (15;17) and inv (16). Of patients, 19.2 had an early relapse. The mean age of relapse in patients was 6.7 ± 3.9 years. Sixty patients (57.7) were alive, and 44 cases (42.3) died during or after therapy. The three years overall survival rate of patients was 42 in this study. According to our data, AML has the same frequency as compared with data from developing countries. But different epidemiological characteristic was a lower rate of three years overall survival in patients. These data may serve the health authorities for more effective environmental and preventive measurements, purposeful allocation of resources for facilitating upto-date diagnostic and treatment modalities, psychological support programs for respective family members and educational purposes. © 2015 Tehran University of Medical Sciences. All rights reserved

A Case Report of Newborn with Thrombocytosis Born to an Opioid-addict Mother

Abstract: Neonatal thrombocytosis is a very rare phenomenon in infants born to addict mothers. It can be due to opioids withdrawal and occurs a few days after delivery. The etiology is unknown and it is eradicated gradually without any complication. The reported neonate was born to a heroin addict mother who has used methadone during pregnancy. The neonate was admitted in 14th day of life in neonatal intensive care unit (NICU) with the diagnosis of withdrawal syndrome and supportive care was administered for him. Thrombocytosis was detected in routine lab tests. There was not any reason for it except his mother’s addiction. The platelet count was 1,168,000 in the first day and decreased gradually during 28 days to 739,000. There was not any complication and no special treatment was administered. This case indicates that thrombocytosis may happen as a part of neonatal abstinence syndrome and is eradicated without any complication. Keywords: Thrombocytosis, Neonatal abstinence syndrome, Opioids, Methadon

Investigation of high-temperature resistance of natural pozzolan-based geopolymers produced with oven and microwave curing

In this study, high-temperature resistances of oven- and microwave-cured pumice-, perlite-, fly ash- and burnt clay-based geopolymer were investigated and, the results were compared with that of the cement mortars. The effect of high-temperature on the matrix microstructure was investigated by SEM and changes in the crystal structure were monitored by XRD analyses. High-temperature experiments were carried out with 3 h exposure to 450, 600, 750 and 900 °C. The results indicated that both oven- and microwave-cured geopolymer mortars are more resistant to high-temperatures at all temperatures than their portland cement counterpart. However, it was also determined that pumice- and perlite-based mortars could not maintain their volumetric stability at elevated temperatures. © 2022 Elsevier LtdTürkiye Bilimsel ve Teknolojik Araştırma Kurumu, TÜBİTAK: 119M950The authors acknowledge the contribution of Ege University Central Research, Test and Analysis Laboratory for SEM analysis and Izmir Katip Celebi University Central Research Laboratory for XRD analysis.This work was supported by the Scientific and Technological Research Council of Turkey (TUBITAK) [Grant No 119M950]

CLINICAL FEATURES AND TREATMENT RESPONSE OF IMMUNE THROMBOCYTOPENIC PURPURA IN INFANTS

To determine the clinical features and treatment outcomes of infant with immune thrombo-cytopenic purpura (ITP). Retrospective analysis of 96 infant ITP patients treated from 1995 to 2005. The data abstracted comprised age, gender, clinical features, and treatment outcomes. The 56 male and 40 female infants had a median age of 3 months. Eighty presented with purpura, sixteen with active mucosal bleeding. The median platelet count was 13000 /l. Seventy-seven infants received intravenous immunoglobulin (IVIG), eighteen steroids and one patient was observed. Ninty-sex (96%) responds to a single course of treatment. Infant with ITP respond favorably to treatment

Investigation of Flexural Strength and Toughness of Fly Ash Based Geopolymer SIFCON

Geopolymers are environmentally friendly construction materials produced by the use of silica and alumina-rich powder materials with high alkaline solutions. Reinforcing the matrix phase with continuous or discontinuous fibers has been applied for many years to increase the tensile strength and energy absorption capacity of composite materials developed for different applications. SIFCON composites are one of them, and they are produced by placing the fibers in the mold and then filling the mold with very fluid matrix phase. However, there is a need for research on the use of geopolymer matrix in SIFCON production. In this study, fly ash-based geopolymer SIFCON composites containing 5% by volume steel fibers were produced and their flexural strength, compressive strength and toughness properties were investigated on both samples that were not exposed to high temperature and exposed to 900°C. In addition, cement-based conventional SIFCON composites with similar flexural strengths with the geopolymer SIFCON were used for comparison. It was determined that the fly ash-based geopolymer SIFCON had higher flexural strength and toughness values than that of the cement-based SIFCON after exposing to high temperature. In addition, for a given flexural strength, geopolymer SIFCON showed a higher compressive strength than that of conventional SIFCON. © 2022, TUBITAK. All rights reserved

A case report of newborn with thrombocytosis born to an opioid-addict mother

Neonatal thrombocytosis is a very rare phenomenon in infants born to addict mothers. It can be due to opioids withdrawal and occurs a few days after delivery. The etiology is unknown and it is eradicated gradually without any complication. The reported neonate was born to a heroin addict mother who has used methadone during pregnancy. The neonate was admitted in 14th day of life in neonatal intensive care unit (NICU) with the diagnosis of withdrawal syndrome and supportive care was administered for him. Thrombocytosis was detected in routine lab tests. There was not any reason for it except his mother's addiction. The platelet count was 1,168,000 in the first day and decreased gradually during 28 days to 739,000. There was not any complication and no special treatment was administered. This case indicates that thrombocytosis may happen as a part of neonatal abstinence syndrome and is eradicated without any complication

Effects of aggregate size and angularity on alkali-silica reaction

WOS: 000233499900013The effects of reactive aggregate size and aggregate angularity on alkali-silica reaction (ASR) were studied. An all-in natural reactive aggregate was used. The coarse aggregate particles were crushed to obtain crushed fine particles. The angularity of the aggregate was determined using ASTM C1252 and EN 933-6 methods. ASTM C1260 accelerated mortar bar test was conducted to compare the ASR expansion caused by various aggregate size fractions. The effect of the size of the particles on ASR expansion was studied by replacing each size fraction of the non-reactive aggregate with the reactive aggregate of the same size. In spite of similarity of the chemical and mineralogical compositions, the crushed aggregate caused higher ASR expansion than the natural aggregate in all size fractions. The summation of the expansions of individual reactive size fractions of both aggregates was found to be higher than that of corresponding control mixtures. (C) 2005 Elsevier Ltd. All rights reserved

Effects of fineness of cement on polynaphthalene sulfonate based superplasticizer-cement interaction

WOS: 000266054500037The effects of fineness of portland cement procured from six different Turkish cement plants, on superplasticizer/cement interaction were investigated. CEM 142.5 type portland cements (PC) were ground into different finenesses ranging from 280 to 550 m(2)/kg Blaine values. The effects of PC fineness on initial fluidity and fluidity loss of superplasticized cement paste were evaluated. It was found that increasing the Blaine fineness of incompatible cement up to a certain level reduced the viscosity of cement pastes but had no marked effect on the yield stress of the paste mixtures. Nevertheless, flow loss and also saturation point at 60 min increased with increasing the cement fineness. In other words, pastes with lower viscosity can be produced by using finer cement and more superplasticizer. (C) 2008 Elsevier Ltd. All rights reserved.Scientific and Technical Research Council of Turkey (TUBITAK)Turkiye Bilimsel ve Teknolojik Arastirma Kurumu (TUBITAK) [MAG-HD-12 (105M083]; BASF chemical companyThe authors would like to thank The Scientific and Technical Research Council of Turkey (TUBITAK) for financial supporting, Project No.: MAG-HD-12 (105M083). The authors also acknowledge Mr. Okan DUYAR from BASF chemical company for material support and testing