DATA PARITY & RETENTION CHECKS IN DIFFERENT DATA CENTERS FOR FINDING DATA LEVEL MISMATCH

Various embodiments of the present invention provide a method and system to automate data parity and retention checks between data centers with parallel data load pipelines. The method comprises, receiving one or more data entities; identifying one or more key metrics to be used; identifies one or more time dimension attribute within which the validation needs to be performed; creating one or more text files based on one or more inputs received; identification of key metrics and time dimension attribute; generates dynamically a Structured Query Language (SQL) for each of the rows from the text files as well as executes the generated scripts separately to capture the values for the corresponding datacenters; and compares the text files based on one or more metric values to get its difference and percentage of difference and updates the captured results

IMPACT OF EDUCATIONAL INTERVENTION ON KNOWLEDGE, ATTITUDE, AND PRACTICES OF URBAN COMMUNITY PHARMACISTS TOWARD ADVERSE DRUG REACTION REPORTING IN A SOUTH INDIAN CITY

ABSTRACTObjective: To assess the knowledge, attitude, and practices (KAP) of community pharmacists toward adverse drug reaction (ADR) reporting and alsoto evaluate the impact of the educational program on community pharmacist's knowledge and perception toward ADR reporting.Methods: A prospective cross-sectional study was carried out by administering a validated questionnaire before and after the educational programon a sample of 26 community pharmacists. The baseline score of pre-training KAP was compared with the post-training KAP. The SPSS statisticalversion 19 was used to compare the difference in the KAP of the pharmacists before and after the educational program. Frequencies and percentagewere used to measure demographic details of the participants.Results: 26 community pharmacists have participated in the study. The mean pre-training KAP score was increased from 4.30±2.02 to mean posttrainingscoreof 7.32±0.94. Afterthe educational program,92.30%(n=24)ofparticipants wereable toidentify potentialriskfactorsresponsibletocauseADRs,and 80.76% (n=21)ofparticipants wereawareof the consequenceof ADRs.Upon educational intervention73.07% (n=19)ofparticipantsdisagreewith thestatementofADR reportingin thecommunity pharmacieslead toadditional workloadandwereconfident about theirknowledgeinADR reportingand monitoring.Conclusion: The study concludes that the educational intervention has increased the KAP of the trained community pharmacists toward ADRreporting.Keywords: Community pharmacists, Adverse drug reaction reporting, Educational intervention, Knowledge, Attitude and practices.Â

Investigating the Detrimental Outcomes of Malicious Activities in the Academic College Libraries

Academic libraries play a key role in encouraging literacy and cultural interest in students, staff and the community. In the present-day world, theft and vandalism has become very common and a severe problem in academic college libraries. This research paper mainly deals with work of the library professionals in investigating the book theft, vandalism, mutilation activities, and planning polices to control these malicious activities. A structured online questionnaire was prepared for the college librarians to the gather data for the research study. The research data was collected from forty library professionals. Insufficient copies of text books are the main cause for vandalism agreed upon by the majority 85% of the respondents. 80% of the library professionals mentioned to have CCTV installation which can reduce malpractices in the libraries As per the research study 100% of respondents agree that by conducting orientation program, checking the requirements of the patrons, providing the necessary resources required by them, by using wire mesh for windows and having a single way for entry and exit will help in combating vandalistic activities in the academic libraries. This study will also help the library professionals as well as the patrons to preserve and guard invaluable academic wealth of libraries for potential generations

Measurement of marine productivity using 15N and 13C tracers: Some methodological aspects

Various experiments involving the measurement of new, regenerated and total productivity using 15N and 13C tracers were carried out in the Bay of Bengal (BOB) and in the Arabian Sea. Results from 15N tracer experiments indicate that nitrate uptake can be underestimated by experiments with incubation time <4 hours. Indirect evidence suggests pico- and nano-phytoplankton, on their dominance over microphytoplankton, can also influence the f-ratios. Difference in energy requirement for assimilation of different nitrogen compounds decides the preferred nitrogen source during the early hours of incubation. Variation in light intensity during incubation also plays a significant role in the assimilation of nitrogen. Results from time course experiments with both 15N and 13C tracers suggest that photoinhibition appears significant in BOB and the Arabian Sea during noon. A significant correlation has been found in the productivity values obtained using 15N and 13C tracers

Nitrogen uptake rates and f-ratios in the Equatorial and Southern Indian Ocean

We report data on nitrate, ammonium and urea uptake rates from the Equatorial and Southern Indian Oceans. Productivity (0.81–2.23 mmol N m–2 d–1) over the Equatorial Indian Ocean was low, but the f-ratio (0.13–0.45) was relatively high. In the Southern Indian Ocean total N-uptake rate varied from 1.7 to 12.3 mmol Nm–2 d–1; it was higher in the Antarctic coast (69S) and lower over most of the Southern Ocean, the lowest being at 58S. The f-ratio also showed significant spatial variation, but was higher compared to values at the Equatorial Indian Ocean. The mean f-ratio in the Southern Indian Ocean was 0.50. The nitrate-specific uptake rates and f-ratios appear to have increased significantly in the recent past relative to earlier estimates. While productivity in the Southern Ocean is comparable to that in the Equatorial Indian Ocean, higher f-ratios in the former underscore its importance in the uptake of CO

Effect of high level iron enrichment on potential nitrogen uptake by marine plankton in the Southern Ocean

Iron fertilization of the Southern Ocean is believed to counter the increasing CO 2 concentration in the atmosphere and the consequent global warming. Though a number of large scale iron enrichment experiments have been done in the recent past in different parts of the world ocean, little effort has been made to understand the effect of iron enrichment on nitrogen uptake rates and f-ratios. Here we assess the effect of iron addition on N-uptake rates and f-ratio in the Indian sector of the Southern Ocean

Methodology for evaluating thermal track buckling in dual gauge tracks with continuous welded rail

In the National Spanish railway network, two types of track gauge with continuous welded rails are currently in use: the Iberian wide gauge (1668 mm) and the standard gauge (1435 mm). In order to improve links and freight traffic between different lines and with the rest of Europe, a dual gauge track with three rails was developed. This solution modifies the classical track configuration, so it is necessary to develop new methodologies and studies to understand its behavior. Among other loads applied on a continuous welded rail track, a considerable rise in temperature induces compressive stresses in the three rails that can lead to lateral track buckling. Moreover, on dual gauge tracks, the addition of the third rail increases the axial compression, which may lead to track instability. For this reason, a three-dimensional continuous welded rail model is developed in this study to be used for dual gauge track buckling analysis on straight tracks subjected to temperature load. The continuous welded rail dual gauge track model consists of beam, solid and spring elements, in which a non-linear behaviour of the ballast is considered. The results obtained may be used to predict the buckling capacity of the continuous welded rail on dual gauge tracks with respect to different parameters such as lateral resist-ance, lateral imperfections, sleeper spacing or torsional stiffness.Villalba Sanchis, I.; Insa Franco, R.; Salvador Zuriaga, P.; Martínez Fernández, P. (2017). Methodology for evaluating thermal track buckling in dual gauge tracks with continuous welded rail. Proceedings of the Institution of Mechanical Engineers, Part F: Journal of Rail and Rapid Transit. 231(3):269-279. doi:10.1177/0954409715626957S269279231

Development and evaluation of a real-time one step Reverse-Transcriptase PCR for quantitation of Chandipura Virus

<p>Abstract</p> <p>Background</p> <p>Chandipura virus (CHPV), a member of family <it>Rhabdoviridae </it>was attributed to an explosive outbreak of acute encephalitis in children in Andhra Pradesh, India in 2003 and a small outbreak among tribal children from Gujarat, Western India in 2004. The case-fatality rate ranged from 55–75%. Considering the rapid progression of the disease and high mortality, a highly sensitive method for quantifying CHPV RNA by real-time one step reverse transcriptase PCR (real-time one step RT-PCR) using TaqMan technology was developed for rapid diagnosis.</p> <p>Methods</p> <p>Primers and probe for P gene were designed and used to standardize real-time one step RT-PCR assay for CHPV RNA quantitation. Standard RNA was prepared by PCR amplification, TA cloning and run off transcription. The optimized real-time one step RT-PCR assay was compared with the diagnostic nested RT-PCR and different virus isolation systems [<it>in vivo </it>(mice) <it>in ovo </it>(eggs), <it>in vitro </it>(Vero E6, PS, RD and Sand fly cell line)] for the detection of CHPV. Sensitivity and specificity of real-time one step RT-PCR assay was evaluated with diagnostic nested RT-PCR, which is considered as a gold standard.</p> <p>Results</p> <p>Real-time one step RT-PCR was optimized using <it>in vitro </it>transcribed (IVT) RNA. Standard curve showed linear relationship for wide range of 10²-10¹⁰(r²= 0.99) with maximum Coefficient of variation (CV = 5.91%) for IVT RNA. The newly developed real-time RT-PCR was at par with nested RT-PCR in sensitivity and superior to cell lines and other living systems (embryonated eggs and infant mice) used for the isolation of the virus. Detection limit of real-time one step RT-PCR and nested RT-PCR was found to be 1.2 × 10⁰PFU/ml. RD cells, sand fly cells, infant mice, and embryonated eggs showed almost equal sensitivity (1.2 × 10²PFU/ml). Vero and PS cell-lines (1.2 × 10³PFU/ml) were least sensitive to CHPV infection. Specificity of the assay was found to be 100% when RNA from other viruses or healthy individual was used.</p> <p>Conclusion</p> <p>On account of the high sensitivity, reproducibility and specificity, the assay can be used for the rapid detection and quantitation of CHPV RNA from clinical samples during epidemics and from endemic areas. The assay may also find application in screening of antiviral compounds, understanding of pathogenesis as well as evaluation of vaccine.</p