105 research outputs found

    Connection between charge-density-wave order and charge transport in the cuprate superconductors

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    Charge-density-wave (CDW) correlations within the quintessential CuO2_2 planes have been argued to either cause [1] or compete with [2] the superconductivity in the cuprates, and they might furthermore drive the Fermi-surface reconstruction in high magnetic fields implied by quantum oscillation (QO) experiments for YBa2_2Cu3_3O6+δ_{6+{\delta}} (YBCO) [3] and HgBa2_2CuO4+δ_{4+{\delta}} (Hg1201) [4]. Consequently, the observation of bulk CDW order in YBCO was a significant development [5,6,7]. Hg1201 features particularly high structural symmetry and recently has been demonstrated to exhibit Fermi-liquid charge transport in the relevant temperature-doping range of the phase diagram, whereas for YBCO and other cuprates this underlying property of the CuO2_2 planes is partially or fully masked [8-10]. It therefore is imperative to establish if the pristine transport behavior of Hg1201 is compatible with CDW order. Here we investigate Hg1201 (TcT_c = 72 K) via bulk Cu L-edge resonant X-ray scattering. We indeed observe CDW correlations in the absence of a magnetic field, although the correlations and competition with superconductivity are weaker than in YBCO. Interestingly, at the measured hole-doping level, both the short-range CDW and Fermi-liquid transport appear below the same temperature of about 200 K. Our result points to a unifying picture in which the CDW formation is preceded at the higher pseudogap temperature by qq = 0 magnetic order [11,12] and the build-up of significant dynamic antiferromagnetic correlations [13]. Furthermore, the smaller CDW modulation wave vector observed for Hg1201 is consistent with the larger electron pocket implied by both QO [4] and Hall-effect [14] measurements, which suggests that CDW correlations are indeed responsible for the low-temperature QO phenomenon

    Nebuliser therapy in the intensive care unit

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    The relationship between identity, lived experience, sexual practices and the language through which these are conveyed has been widely debated in sexuality literature. For example, ‘coming out’ has famously been conceptualised as a ‘speech act’ (Sedgwick 1990) and as a collective narrative (Plummer 1995), while a growing concern for individuals’ diverse identifications in relations to their sexual and gender practices has produced interesting research focusing on linguistic practices among LGBT-identified individuals (Leap 1995; Kulick 2000; Cameron and Kulick 2006; Farqhar 2000). While an explicit focus on language remains marginal to literature on sexualities (Kulick 2000), issue of language use and translation are seldom explicitly addressed in the growing literature on intersectionality. Yet intersectional perspectives ‘reject the separability of analytical and identity categories’ (McCall 2005:1771), and therefore have an implicit stake in the ‘vernacular’ language of the researched, in the ‘scientific’ language of the researcher and in the relationship of continuity between the two. Drawing on literature within gay and lesbian/queer studies and cross-cultural studies, this chapter revisits debates on sexuality, language and intersectionality. I argue for the importance of giving careful consideration to the language we choose to use as researchers to collectively define the people whose experiences we try to capture. I also propose that language itself can be investigated as a productive way to foreground how individual and collective identifications are discursively constructed, and to unpack the diversity of lived experience. I address intersectional complexity as a methodological issue, where methodology is understood not only as the methods and practicalities of doing research, but more broadly as ‘a coherent set of ideas about the philosophy, methods and data that underlie the research process and the production of knowledge’ (McCall 2005:1774). My points are illustrated with examples drawn from my ethnographic study on ‘lesbian’ identity in urban Russia, interspersed with insights from existing literature. In particular, I aim to show that an explicit focus on language can be a productive way to explore the intersections between the global, the national and the local in cross-cultural research on sexuality, while also addressing issues of positionality and accountability to the communities researched

    Human tooth germ stem cells preserve neuro-protective effects after long-term cryo-preservation

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    The use of mesenchymal stem cells (MSCs) has been shown to be promising in chronic disorders such as diabetes, Alzheimer's dementia, Parkinson's disease, spinal cord injury and brain ischemia. Recent studies revealed that human tooth germs (hTG) contain MSCs which can be easily isolated, expanded and cryo-preserved. In this report, we isolated human tooth germ stem cells (hTGSCs) with MSC characteristics from third molar tooth germs, cryo-preserved them at -80°C for 6 months, and evaluated for their surface antigens, expression of pluri-potency associated genes, differentiation capacity, karyotype, and proliferation rate. These characteristics were compared to their non-frozen counterparts. In addition, neuro-protective effects of cryo-preserved cells on neuro-blastoma SH-SY5Y cells were also assessed after exposure to stress conditions induced by hydrogen-peroxide (oxidative stress) and paclitaxel (microtubule stabilizing mitotic inhibitor). After long term cryo-preservation hTGSCs expressed surface antigens CD29, CD73, CD90, CD105, and CD166, but not CD34, CD45 or CD133, which was typical for non-frozen hTGSCs. Cryo-preserved hTGSCs were able to differentiate into osteo-, adipo- and neuro-genic cells. They also showed normal karyotype after high number of population doublings and unchanged proliferation rate. On the other hand, cryo-preserved cells demonstrated a tendency for lower level of pluri-potency associated gene expression (nanog, oct4, sox2, klf4, c-myc) than non-frozen hTGSCs. hTGSCs conditioned media increased survival of SH-SY5Y cells exposed to oxidative stress or paclitaxel. These findings confirm that hTGSCs preserve their major characteristics and exert neuro-protection after long-term cryopreservation, suggesting that hTGSCs, harvested from young individuals and stored for possible use later as they grow old, might be employed in cellular therapy of age-related degenerative disorders. © Bentham Science Publishers Ltd

    The Feeling of Numbers: emotions in everyday engagements with data and their visualisation

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    This paper highlights the role that emotions play in engagements with data and their visualisation. To date, the relationship between data and emotions has rarely been noted, in part because data studies have not attended to everyday engagements with data. We draw on an empirical study to show a wide range of emotional engagements with diverse aspects of data and their visualisation, and so demonstrate the importance of emotions as vital components of making sense of data. We nuance the argument that regimes of datafication, in which numbers, metrics and statistics dominate, are characterised by a renewed faith in objectivity and rationality, arguing that in datafied times, it is not only numbers but also the feeling of numbers that is important. We build on the sociology of a) emotions and b) the everyday to do this, and in so doing, we contribute to the development of a sociology of data

    Punk is just a state of mind: Exploring what punk means to older punk women

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    What does punk mean to older punk women? And how are such understandings interwoven with experiences of ageing and gender? The complexity in defining punk has been noted and it has been suggested that this complexity in part results from punk’s dislike of being labelled/categorised. Drawing upon interviews with 22 self-identifying older punk women, this article considers how they conceived punk as ‘a state of mind’, exploring the four shared punk values seen to comprise this: DIY, subversion, political consciousness and community. An unpacking of these values in terms of what they might ‘look like’ and how they are put into action by the women highlights the considerable roles ageing and gender play

    Masculinity, sexuality and vulnerability in 'working' with young men in South African contexts: 'you feel like a fool and an idiot...a loser'

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    South Africa has seen a rapid increase in scholarship and programmatic interventions focusing on gender and sexuality, and more recently on boys, men and masculinities. In this paper, we argue that a deterministic discourse on men's sexuality and masculinity in general is inherent in many current understandings of adolescent male sexuality, which tend to assume that young women are vulnerable and powerless and young men are sexually powerful and inevitably also the perpetrators of sexual violence. Framed within a feminist, social constructionist the oretical perspective, the current research looked at how the masculinity and sexuality of South African young men is constructed, challenged or maintained. Focus groups were conducted with young men between the ages of 15 and 20 years from five different schools in two regions of South Africa, the Western and Eastern Cape. Data were analysed using Gilligan's listening guide method. Findings suggest that participants in this study have internalised the notion of themselves as dangerous, but were also exploring other possible ways of being male and being sexual, demonstrating more complex experiences of manhood. We argue for the importance of documenting and highlighting the precariousness, vulnerability and uncertainty of young men in scholarly and programmatic work on masculinities.IBS

    “It’s not a simple thing, co-publishing”: challenges of co-authorship between supervisors and students in South African higher educational contexts

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    Knowledge production in South Africa remains framed by the legacies of apartheid. Developing emerging authors and local knowledges through co-authorship between supervisors and post graduate students is an important strategy aimed at challenging these legacies. This paper draws on in-depth interviews with students and supervisors to explore their experiences of co-authorship. Findings indicate that while insisting that co-authoring has value, several students also note their discomfort with elements of the process. While insisting students’ work be disseminated, and expressing willingness to engage in the mentoring that this requires, supervisors also articulate discomfort with processes offering opportunities for personal career development. Given increasing emphasis on co-authorship we suggest the power inequalities expressed through the supervisor/student relationship be made more transparent. Knowledge production through co-authorship is best served by collaborations between authors who are more equally empowered and who are more critically aware of the challenges such collaborations are likely to present.Web of Scienc

    In the Margins: The Impact of Sexualised Images on the Mental Health of Ageing Women

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    This paper describes key findings of a study exploring how a cohort of 16 rural Australian women aged over 60 years think, feel and respond to the prevalence of sexualised imagery in the media. The qualitative research framework was informed by Feminist Standpoint Theory. Participants in three focus groups responded to semi-structured questions and prompts, interspersed with viewing examples of sexualised images. Five strong thematic categories emerged: concern for the harmful impacts of sexualised images on the vulnerable, the media’s portrayal of sexual content with a focus on physical appearance and youth, descriptions of the impact of viewing sexualised images, moderators of the impact of sexualised images on well-being, and marginalisation of women in the media. Findings from this research indicate that sexualised images in the media do have an impact on older women’s self image and mental health in numerous ways and in a range of situations. Emotional impacts included sadness, anger, concern, envy, desensitisation, marginalisation, and discomfort that their appearance was being judged by others. A strong sense of self apart from appearance, feeling valued by family and community, ignoring or overlooking media content, and being aware that media images are not real and attainable helped buffer the link between sexualised images and well-being. Another important finding is that the impact is variable: women may experience different responses to similar sexualised content depending on a range of social, health and lifestyle factors affecting them at any given time

    "Give me some space" : exploring youth to parent aggression and violence

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    A small scale qualitative project, undertaken by an interdisciplinary domestic violence research group involving academic researchers and research assistants, with colleagues from Independent Domestic Abuse Services (IDAS), investigated youth aggression and violence against parents. Following the literature review, data was generated through several research conversations with young people (n = 2), through semi-structured interviews with mothers (n = 3) and practitioners (n = 5), and through a practitioner focus group (n = 8). Thematic analysis and triangulation of the data from parents, practitioners and young people, elicited interconnected and complex overarching themes. Young people could be both victim and perpetrator. The witnessing or experiencing of domestic aggression and violence raised the concept of ‘bystander children’. The impact of young people experiencing familial violence was underestimated by parents. For practitioners, the effects of working with domestic violence was shown to be significant - both positively and negatively
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