10 research outputs found
Современные проблемы развития теории функционально устойчивых сложных систем управления
Employment is believed to function as a ‘turning point’ for released offenders. Several theories state that employment can diminish recidivism, and offer different mechanisms to connect employment and crime, such as job stability and job quality. This study examines the effect of employment and employment characteristics on recidivism among Dutch ex-prisoners. Although recidivism risks are high among this group, longitudinal research on the effect of employment on recidivism risks is scarce. We based our analyses on longitudinal data of the Prison Project (n=842) and found that job stability reduces the risk of recidivism. The results indicate that not the guidance to a job, or a high-quality job, but the guidance to stable employment could help to reduce crime rates among this high-risk offender group
Down before they go in : A study on pre-prison labour market attachment
This study is concerned with describing the employment history of prisoners. Past labour market performance is a major predictor of later performances. Yet, the substantial field of reentry research paid little attention to pre-prison employment patterns and the magnitudes of labour market disadvantage that prisoners already face prior to their imprisonment. Using data on nearly 2000 Dutch prisoners and a representative sample of the Dutch labour force, we find that underemployment is a longstanding feature of prisoners' working lives. Starting with a low educational attainment, their subsequent employment career is characterized by long periods of unemployment, "off-the-books" employment, dismissals and job shifts. This results in a marginalized labour market position prior to imprisonment. The findings emphasize that the labour market (re)integration of ex-prisoners is a pressing social and public policy challenge, and stress the importance of skill attainment and work experience among high-risk groups
Down before they go in : A study on pre-prison labour market attachment
This study is concerned with describing the employment history of prisoners. Past labour market performance is a major predictor of later performances. Yet, the substantial field of reentry research paid little attention to pre-prison employment patterns and the magnitudes of labour market disadvantage that prisoners already face prior to their imprisonment. Using data on nearly 2000 Dutch prisoners and a representative sample of the Dutch labour force, we find that underemployment is a longstanding feature of prisoners' working lives. Starting with a low educational attainment, their subsequent employment career is characterized by long periods of unemployment, "off-the-books" employment, dismissals and job shifts. This results in a marginalized labour market position prior to imprisonment. The findings emphasize that the labour market (re)integration of ex-prisoners is a pressing social and public policy challenge, and stress the importance of skill attainment and work experience among high-risk groups
Terug naar huis? Veranderingen in woonsituaties tijdens detentie en na vrijlating
Criminal Justice: Legitimacy, accountability, and effectivit
Imprisonment length and post-prison employment prospects
This study considers the relationship between imprisonment length and employment outcomes. The data are a unique prospective, longitudinal study of Dutch pretrial detainees (N = 702). All subjects thus experience prison confinement of varying lengths, although the durations are relatively short (mean = 3.8 months; median = 3.1 months). This contrasts with prior research that was limited to the study of American prison sentences spanning an average of 2 years. These data thus fill a gap in the empirical base concerning short-term confinement, which is the norm in the United States (e.g., jail incarceration) and other Western countries. Using a comprehensive array of pre-prison covariates, a propensity score methodology is used to examine the dose-response relationship between imprisonment length and a variety of employment outcomes. The results indicate that, among prison lengths less than 6 months in duration, longer confinement is largely uncorrelated with employment. In contrast, among spells in excess of 6 months, longer imprisonment length seems to worsen employment prospects
The value of maintaining cognition in patients with mild cognitive impairment: The innovation headroom and potential cost-effectiveness of roflumilast
INTRODUCTION: Early health-technology assessment can support discussing scarce resource allocation among stakeholders. We explored the value of maintaining cognition in patients with mild cognitive impairment (MCI) by estimating: (1) the innovation headroom and (2) the potential cost effectiveness of roflumilast treatment in this population. METHODS: The innovation headroom was operationalized by a fictive 100% efficacious treatment effect, and the roflumilast effect on memory word learning test was assumed to be associated with 7% relative risk reduction of dementia onset. Both were compared to Dutch setting usual care using the adapted International Pharmaco-Economic Collaboration on Alzheimer's Disease (IPECAD) open-source model. RESULTS: The total innovation headroom expressed as net health benefit was 4.2 (95% bootstrap interval: 2.9-5.7) quality-adjusted life years (QALYs). The potential cost effectiveness of roflumilast was k€34 per QALY. DISCUSSION: The innovation headroom in MCI is substantial. Although the potential cost effectiveness of roflumilast treatment is uncertain, further research on its effect on dementia onset is likely valuable
Associations between plasma kynurenines and cognitive function in individuals with normal glucose metabolism, prediabetes and type 2 diabetes: the Maastricht Study
Aims/hypothesis
Studies investigating associations between kynurenines and cognitive function have generally been small, restricted to clinical samples or have found inconsistent results, and associations in the general adult population, and in individuals with type 2 diabetes in particular, are not clear. Therefore, the aim of the present study was to investigate cross-sectional associations between plasma kynurenines and cognitive function in a cohort of middle-aged participants with normal glucose metabolism, prediabetes (defined as impaired fasting glucose and/or impaired glucose tolerance) and type 2 diabetes.
Methods
Plasma kynurenines were quantified in 2358 participants aged 61 ± 8 years. Cross-sectional associations of kynurenines with cognitive impairment and cognitive domain scores were investigated using logistic, multiple linear and restricted cubic spline regression analyses adjusted for several confounders.
Results
Effect modification by glucose metabolism status was found for several associations with cognitive impairment, hence analyses were stratified. In individuals with prediabetes, 3-hydroxykynurenine (OR per SD 0.59 [95% CI 0.37, 0.94]) and 3-hydroxyanthranilic acid (0.67 [0.47, 0.96]) were associated with lower odds of cognitive impairment after full adjustment. In individuals with type 2 diabetes, kynurenine (0.80 [0.66, 0.98]), 3-hydroxykynurenine (0.82 [0.68, 0.99]), kynurenic acid (0.81 [0.68, 0.96]), xanthurenic acid (0.73 [0.61, 0.87]) and 3-hydroxyanthranilic acid (0.73 [0.60, 0.87]) were all associated with lower odds of cognitive impairment. Kynurenic acid (β per SD 0.07 [95% CI 0.02, 0.13]) and xanthurenic acid (0.06 [0.01, 0.11]) were also associated with better executive function/attention. No associations were observed in individuals with normal glucose metabolism.
Conclusions/interpretation
Several kynurenines were cross-sectionally associated with lower odds of cognitive impairment and better cognitive functioning in type 2 diabetes, while less widespread associations were seen in prediabetes. Low levels of kynurenines might be involved in the pathway of type 2 diabetes and cognitive decline but this needs further studies
Associations between plasma kynurenines and cognitive function in individuals with normal glucose metabolism, prediabetes and type 2 diabetes:the Maastricht Study
Aims/hypothesis
Studies investigating associations between kynurenines and cognitive function have generally been small, restricted to clinical samples or have found inconsistent results, and associations in the general adult population, and in individuals with type 2 diabetes in particular, are not clear. Therefore, the aim of the present study was to investigate cross-sectional associations between plasma kynurenines and cognitive function in a cohort of middle-aged participants with normal glucose metabolism, prediabetes (defined as impaired fasting glucose and/or impaired glucose tolerance) and type 2 diabetes.
Methods
Plasma kynurenines were quantified in 2358 participants aged 61 ± 8 years. Cross-sectional associations of kynurenines with cognitive impairment and cognitive domain scores were investigated using logistic, multiple linear and restricted cubic spline regression analyses adjusted for several confounders.
Results
Effect modification by glucose metabolism status was found for several associations with cognitive impairment, hence analyses were stratified. In individuals with prediabetes, 3-hydroxykynurenine (OR per SD 0.59 [95% CI 0.37, 0.94]) and 3-hydroxyanthranilic acid (0.67 [0.47, 0.96]) were associated with lower odds of cognitive impairment after full adjustment. In individuals with type 2 diabetes, kynurenine (0.80 [0.66, 0.98]), 3-hydroxykynurenine (0.82 [0.68, 0.99]), kynurenic acid (0.81 [0.68, 0.96]), xanthurenic acid (0.73 [0.61, 0.87]) and 3-hydroxyanthranilic acid (0.73 [0.60, 0.87]) were all associated with lower odds of cognitive impairment. Kynurenic acid (β per SD 0.07 [95% CI 0.02, 0.13]) and xanthurenic acid (0.06 [0.01, 0.11]) were also associated with better executive function/attention. No associations were observed in individuals with normal glucose metabolism.
Conclusions/interpretation
Several kynurenines were cross-sectionally associated with lower odds of cognitive impairment and better cognitive functioning in type 2 diabetes, while less widespread associations were seen in prediabetes. Low levels of kynurenines might be involved in the pathway of type 2 diabetes and cognitive decline but this needs further studies.publishedVersio
Not Just Any Job Will Do: A Study on Employment Characteristics and Recidivism Risks After Release
Ex-prisoners’ recidivism risks are high. Several theories state that employment can reduce these risks but emphasize that the protective role of employment is conditional on job qualities (work intensity, job duration, etc.). Longitudinal research on the role of employment in ex-prisoners’ recidivism patterns is scarce, and most existing work used a simplistic employment measure (i.e., employed vs. unemployed), leaving the topic of job quality underexplored. This study examines the association between employment characteristics and recidivism among Dutch ex-prisoners. Using longitudinal data of the Prison Project (n = 714), we found that not just any job, but particularly stable employment and jobs with a higher occupational level could help reduce crime rates among these high-risk offenders. Many ex-prisoners face a human capital deficit that complicates the guidance to high-quality jobs. It might, however, be possible to help place ex-prisoners in stable employment.Criminal Justice: Legitimacy, accountability, and effectivit