Efektivitas Model POGIL untuk Meningkatkan Self Confidence dan Penguasaan Konsep Larutan Penyangga Peserta Didik

This study aims to describe the effectiveness of the POGIL model to increase students' self-confidence and mastery of the buffer solution concept. The research sample was taken using cluster random sampling technique, obtained class XI IPA 3 as the experimental class and XI IPA 4 as the control class. This study used a quasi-experimental method with pretest-posttest control group design. The POGIL model is said to be effective if it shows a significant difference in the value of n-Gain self confidence and students' mastery of concepts between the experimental class and the control class. The results showed that the POGIL model was effective in increasing students' self-confidence and mastery of the buffer solution concept.Keywords: POGIL models, self confidence, mastery of concepts, buffer solution Penelitian ini bertujuan untuk mendeskripsikan efektivitas model POGIL untuk meningkatkan self confidence dan penguasaan konsep larutan penyangga peserta didik. Sampel penelitian diambil menggunakan teknik cluster random sampling, diperoleh kelas XI IPA 3 sebagai kelas eksperimen dan XI IPA 4 sebagai kelas kontrol. Penelitian ini menggunakan metode kuasi eksperimen dengan pretest-postest control grup design. Model POGIL dikatakan efektif apabila menunjukkan perbedaan nilai n-Gain self confidence dan penguasaan konsep peserta didik yang signifikan antara kelas eksperimen dan kelas kontrol. Hasil penelitian menunjukkan bahwa model POGIL efektif dalam meningkatkan self confidence dan penguasaan konsep larutan penyangga peserta didik.Kata kunci: model POGIL, self confidence, penguasaan konsep, larutan penyangg

Rancangan Mini Ekosistem bagi Budi Daya Ikan Nila (Oreochromis niloticus) dan Tanaman Genjer (Limnocharis flava) di dalam Ember yang Dilengkapi dengan Sistem Peringatan Amonia

Environmental conditions and fish stocking density in tilapia cultivation (Oreochromis niloticus) are important factors in determining the success of the cultivation process and supporting optimal fish growth. This study used four treatments, namely A, B, C, and D, for 3, 5, 7, and 9 fish, respectively. The purpose of this study was to determine the effect of raccoon tail plants (Ceratophyllum demersum) and genjer plants (Limnocharis flava) on tilapia mortality, determine the ratio of feed conversion and the effect on ammonia concentrations, determine the effect of ammonia concentrations on the productivity of genjer plants, determine the warning system modeling on ammonia concentrations, as well as calculate mass and energy balance in the cultivation system of tilapia and genjer. The result is that the planting of raccoon tails and genjer in the system significantly affects tilapia mortality. The average value of feed conversion ratio from treatments A, B, C, and D were 1.75; 1.36; 3.51; and 2.87, respectively. The effect is significant and directly proportional to ammonia concentration and genjer productivity. The ammonia warning system modeling is in the form of linear equations, namely y = 0.2085x - 0.0193 with R2 = 0.9692. This system's balance of mass and energy can be divided into three subsystems, namely, fish acclimatization, fish cultivation, and genjer cultivation.   Keywords: ammonia, genjer, modelling, tilapi

Risiko dan Peluang Industri Makanan Rumah Tangga dengan Sistem On-Line dalam Masa Pandemi Covid-19 di DIY

Dalam masa pandemi Covid-19, sistem pemesanan dan pengantaran online pada industri makanan rumah tangga merupakan sebuah alternatif untuk memenuhi kebutuhan pangan konsumen tanpa harus keluar rumah sekaligus sebagai penggerak ekonomi nasional. Namun demikian, isu keamanan pangan, risiko transmisi virus, dan kehalalan makanan masih menjadi tantangan dalam menjalankan bisnis tersebut dengan banyaknya produk industri makanan rumah tangga yang belum beregistrasi dan bersertifikasi halal. Penelitian ini bertujuan mengkaji tentang bagaimana persepsi stakeholder industri makanan rumah tangga dengan sistem online di masa pandemi Covid-19 terkait: 1) Risiko kesehatan dan kehalalan produk 2) Peluang ekonomi bisnis makanan online 3) Praktik pengelolaan bisnis makanan untuk meminimalisasi risiko dan memaksimalkan peluang penjualan makanan secara online. Penelitian ini adalah penelitian kualitatif dengan desain deskriptif yang dilaksanakan melalui wawancara online pada bulan Januari-Februari di DIY. Responden adalah produsen makanan di DIY, menyelenggarakan produksi makanan komersial skala rumah tangga selama pandemi, melaksanakan sistem penjualan makanan secara online, dan tidak memiliki toko offline. Pengumpulan data dilakukan dengan metode purposive sampling. Metode triangulasi dilakukan dengan melakukan wawancara kepada ahli keamanan dan kehalalan pangan dan konsumen industri makanan rumahan dengan total jumlah responden 8 orang. Industri makanan skala rumah tangga dalam masa pandemi Covid-19 memberikan dampak positif pada penguatan ekonomi rumah tangga dan peluang usaha. Risiko keamanan dan kehalalan pangan muncul dari minimnya pengetahuan produsen tentang keamanan dan kehalalan pangan, keterbatasan sumber daya, serta produk yang dihasilkan belum tersertifikasi. Risiko tersebut dapat diminimalkan dengan kolaborasi antara produsen, konsumen dan pemerintah untuk mewujudkan pangan yang aman dan halal

Efisiensi Dan Produktivitas Dalam Mengoptimalkan Bahan Baku Detergen Pencuci Piring Untuk Mendukung UMKM Desa Buaran Bambu, Kecamatan Paku Haji, Kabupaten Tangerang

AbstrakBanyak cara untuk melakukan peningkatan sumber daya manusia pada zaman sekarang, pelaksanaan dapat dilakukan dengan berbagai cara dan metode yaitu dengan memberdayakan masyarakat. Pemberdayaan ini menggunakan pendekatan melalui organisasi-organisasi swadaya masyarakat, seperti Karang Taruna, Dharma Wanita, Ibu-ibu PKK, ataupun kelompok keagamaan. Kami melaksanakan program pemberdayaan ini bersama Ibu-ibu PKK Desa Buaran Bambu, Kecamatan Paku Haji, Kabupaten Tangerang melalui pelatihan dan pendampingan produksi detergen pencuci piring. Tujuan dan target yang ingin dicapai dalam kegiatan ini adalah Ibu-ibu PKK untuk memperbaiki perekonomian desa diperlukan wadah untuk merangkul masyarakat sekitar, dengan merealisasikan Ibu-ibu PKK Desa Buaran Bambu lebih kuat, lebih produktif, kreatif, dan responsif. Untuk mencapai tujuan ini, tim Pengabdian Kepada Masyarakat Program Studi Teknik Industri telah memberikan bimbingan, pelatihan dan praktek kepada Ibu-ibu PKK dalam memproduksi detergen pencuci piring.Keywords: Productivity, Dishwashing Detergent, PK

EKSPLORASI PENGGUNAAN TEKNOLOGI 5G DALAM MENDORONG INOVASI PEMBELAJARAN

Penelitian ini mengeksplorasi potensi Teknologi 5G dalam mendorong inovasi pembelajaran. Dengan fokus pada kecepatan tinggi, responsivitas, dan integrasi teknologi canggih, penelitian ini memberikan wawasan mendalam tentang dampak Teknologi 5G pada pembelajaran. Melalui metode studi literatur, temuan utama mencakup peningkatan aksesibilitas dan responsivitas pembelajaran daring, pemanfaatan augmented reality (AR) dan virtual reality (VR) untuk pengalaman belajar yang lebih immersif, serta dukungan Internet of Things (IoT) untuk pembelajaran yang terpersonalisasi. Namun, tantangan keamanan data, isu etika, dan ketidaksetaraan akses menjadi fokus penting dalam implementasi Teknologi 5G di pendidikan. Penelitian ini menyimpulkan bahwa, dengan mitigasi risiko yang tepat, Teknologi 5G dapat menjadi pilar utama dalam membentuk masa depan pendidikan yang adaptif dan inklusif

DjinniChip: evaluation of a novel molecular rapid diagnostic device for the detection of Chlamydia trachomatis in trachoma-endemic areas.

BACKGROUND: The clinical signs of active trachoma are often present in the absence of ocular Chlamydia trachomatis infection, particularly following mass drug administration. Treatment decisions following impact surveys and in post-control surveillance for communities are currently based on the prevalence of clinical signs, which may result in further unnecessary distribution of mass antibiotic treatment and the increased spread of macrolide resistance alleles in 'off-target' bacterial species. We therefore developed a simple, fast, low cost diagnostic assay (DjinniChip) for diagnosis of ocular C. trachomatis for use by trachoma control programmes. METHODS: The study was conducted in the UK, Germany and Tanzania. For clinical testing in Tanzania, specimens from a sample of 350 children between the ages of 7 to 15 years, which were part of a longitudinal cohort that began in February 2012 were selected. Two ocular swabs were taken from the right eye. The second swab was collected dry, kept cool in the field and archived at - 80 °C before sample lysis for DjinniChip detection and parallel nucleic acid purification and detection/quantification by qPCR assay. RESULTS: DjinniChip was able to reliably detect > 10 copies of C. trachomatis per test and correctly identified 7/10 Quality Control for Molecular Diagnostics C. trachomatis panel samples, failing to detect 3 positive samples with genome equivalent amounts ≤ 10 copies. DjinniChip performed well across a range of typical trachoma field conditions and when used by lay personnel using a series of mock samples. In the laboratory in Tanzania, using clinical samples the sensitivity and specificity of DjinniChip for C. trachomatis was 66% (95% CI 51-78) and 94.8 (95% CI 91-97%) with an overall accuracy of 90.1 (95% CI 86.4-93). CONCLUSIONS: DjinniChip performance is extremely promising, particularly its ability to detect low concentrations of C. trachomatis and its usability in field conditions. The DjinniChip requires further development to reduce inhibition and advance toward a closed system. DjinniChip results did not vary between local laboratory results and typical trachoma field settings, illustrating its potential for use in low-resource areas to prevent unnecessary rounds of MDA and to monitor for C. trachomatis recrudescence

Corrigendum:Multidisciplinary Tinnitus Research: Challenges and Future Directions From the Perspective of Early Stage Researchers (Front. Aging Neurosci., (2021), 13, (647285), 10.3389/fnagi.2021.647285)

In the original article, there was an error. For the sentence “NMDA receptor antagonists (AM-101) have been discontinued in phase III for not meeting endpoints (van de Heyning et al., 2014)” there was a typographical error (phase III should have been phase II). In addition, it was brought to our attention that clinical trials for AM-101 are ongoing. A correction has been made to section 6. Treatment Development, Subsection 6.4. Pharmacology-Based Interventions, paragraph 1. The corrected paragraph is below. A wide variety of therapeutic drugs have been used to relieve tinnitus (Elgoyhen and Langguth, 2010). For acute tinnitus, a dose-dependent reduction in tinnitus intensity was observed with intravenous lidocaine (Trellakis et al., 2006). However, its use is controversial due to its short-lasting response, its potentially life threatening arrhythmogenic side effects, and the low bioavailability of its oral form (Israel et al., 1982; Trellakis et al., 2007; Gil-Gouveia and Goadsby, 2009). A potential goal of pharmacologic tinnitus research could be to identify the mechanism by which lidocaine interferes with tinnitus and mimic this effect using a drug with better tolerance that can be orally administered. For chronic tinnitus, the off-label use of medicines like betahistine (Hall et al., 2018d), anticonvulsants (Hoekstra et al., 2011), and glutamate receptor antagonists have shown little or no effect in clinical trials. Prescription of antidepressants and benzodiazepines is limited to tinnitusassociated comorbidities such as depression, insomnia and anxiety (Langguth et al., 2019). Moreover, three clinical research programs, in the last few years, were discontinued in phase II and III. AMPA antagonist selurampanel (BGG492) has not resulted in a new compound (Cederroth et al., 2018). NMDA receptor antagonists (AM-101) did not meet the primary endpoint of improving minimum masking level in acute tinnitus in a phase II clinical trial but showed improvement for tinnitus loudness, annoyance, sleep difficulties, and tinnitus impact in patients with tinnitus after noise trauma or otitis media (van de Heyning et al., 2014). Many other treatments decreasing tinnitus percept or targeting central auditory processing pathways are at a preclinical phase (Schilder et al., 2019). The modulator of voltage-gated potassium channels (Kv3.1) (AUT00063) was not effective in alleviating tinnitus symptoms (Hall et al., 2019b). The authors apologize for this error and state that this does not change the scientific conclusions of the article in any way. The original article has been updated

Multidisciplinary Tinnitus Research: Challenges and Future Directions from the Perspective of Early Stage Researchers

Tinnitus can be a burdensome condition on both individual and societal levels. Many aspects of this condition remain elusive, including its underlying mechanisms, ultimately hindering the development of a cure. Interdisciplinary approaches are required to overcome long-established research challenges. This review summarizes current knowledge in various tinnitus-relevant research fields including tinnitus generating mechanisms, heterogeneity, epidemiology, assessment, and treatment development, in an effort to highlight the main challenges and provide suggestions for future research to overcome them. Four common themes across different areas were identified as future research direction: (1) Further establishment of multicenter and multidisciplinary collaborations; (2) Systematic reviews and syntheses of existing knowledge; (3) Standardization of research methods including tinnitus assessment, data acquisition, and data analysis protocols; (4) The design of studies with large sample sizes and the creation of large tinnitus-specific databases that would allow in-depth exploration of tinnitus heterogeneity

Multidisciplinary Tinnitus Research: Challenges and Future Directions from the Perspective of Early Stage Researchers

Tinnitus can be a burdensome condition on both individual and societal levels. Many aspects of this condition remain elusive, including its underlying mechanisms, ultimately hindering the development of a cure. Interdisciplinary approaches are required to overcome long-established research challenges. This review summarizes current knowledge in various tinnitus-relevant research fields including tinnitus generating mechanisms, heterogeneity, epidemiology, assessment, and treatment development, in an effort to highlight the main challenges and provide suggestions for future research to overcome them. Four common themes across different areas were identified as future research direction: (1) Further establishment of multicenter and multidisciplinary collaborations; (2) Systematic reviews and syntheses of existing knowledge; (3) Standardization of research methods including tinnitus assessment, data acquisition, and data analysis protocols; (4) The design of studies with large sample sizes and the creation of large tinnitus-specific databases that would allow in-depth exploration of tinnitus heterogeneity